In Bayesian learning of Gaussian graphical model structure, it is common to restrict attention to certain classes of graphs and approximate the posterior distribution by repeatedly moving from one graph to another, using MCMC or methods such as stochastic shotgun search (SSS). I give two corrected versions of an algorithm for non-decomposable graphs and discuss random graph distributions, in particular as prior distributions. The main topic of the thesis is Bayesian structure-learning with forests or trees. Restricting attention to these graphs can be justified using theorems on random graphs. I describe how to use the Chow$\unicode{x2013}$Liu algorithm and the Matrix Tree Theorem to find the MAP forest and certain quantities in the posterior distribution on trees. I give adapted versions of MCMC and SSS for approximating the posterior distribution for forests and trees, and systems for storing these graphs so that it is easy to choose moves to neighbouring graphs. Experiments show that SSS with trees does well when the true graph is a tree or sparse graph. SSS with trees or forests does better than SSS with decomposable graphs in certain cases. Graph priors improve detection of hubs but need large ranges of probabilities. MCMC on forests fails to mix well and MCMC on trees is slower than SSS. (For a longer abstract see the thesis.)

Ovarian Cancer (OC) is type of female reproductive malignancy which can be found among young girls and mostly the women in their fertile or reproductive. There are few number of cysts are dangerous and may it cause cancer. So, it is very important to predict and it can be from different types of screening are used for this detection using Transvaginal Ultrasonography (TVUS) screening. In this research, we employed an actual datasets called PLCO with TVUS screening and three machine learning (ML) techniques, respectively Random Forest KNN, and XGBoost within three target variables. We obtained a best performance from this algorithms as far as accuracy, recall, f1 score and precision with the approximations of 99.50%, 99.50%, 99.49% and 99.50% individually. The AUC score of 99.87%, 98.97% and 99.88% are observed in these Random Forest, KNN and XGB algorithms .This approach helps assist physicians and suspects in identifying ovarian risks early on, reducing ovarian malignancy-related complications and deaths.

Cardiovascular disease, especially heart failure is one of the major health hazard issues of our time and is a leading cause of death worldwide. Advancement in data mining techniques using machine learning (ML) models is paving promising prediction approaches. Data mining is the process of converting massive volumes of raw data created by the healthcare institutions into meaningful information that can aid in making predictions and crucial decisions. Collecting various follow-up data from patients who have had heart failures, analyzing those data, and utilizing several ML models to predict the survival possibility of cardiovascular patients is the key aim of this study. Due to the imbalance of the classes in the dataset, Synthetic Minority Oversampling Technique (SMOTE) has been implemented. Two unsupervised models (K-Means and Fuzzy C-Means clustering) and three supervised classifiers (Random Forest, XGBoost and Decision Tree) have been used in our study. After thorough investigation, our results demonstrate a superior performance of the supervised ML algorithms over unsupervised models. Moreover, we designed and propose a supervised stacked ensemble learning model that can achieve an accuracy, precision, recall and F1 score of 99.98%. Our study shows that only certain attributes collected from the patients are imperative to successfully predict the surviving possibility post heart failure, using supervised ML algorithms.

In education, open-ended quiz questions have become an important tool for assessing the knowledge of students. Yet, manually preparing such questions is a tedious task, and thus automatic question generation has been proposed as a possible alternative. So far, the vast majority of research has focused on generating the question text, relying on question answering datasets with readily picked answers, and the problem of how to come up with answer candidates in the first place has been largely ignored. Here, we aim to bridge this gap. In particular, we propose a model that can generate a specified number of answer candidates for a given passage of text, which can then be used by instructors to write questions manually or can be passed as an input to automatic answer-aware question generators. Our experiments show that our proposed answer candidate generation model outperforms several baselines.

Coronavirus Diaries is a series of dispatches exploring how the coronavirus is affecting people's lives. This as-told-to essay is based on a conversation with An Luu, a 21-year-old senior at Rice University in Houston, who got a false positive due to a COVID-19 test glitch earlier this month. Luu was one of many Rice students whose positive (later discovered to be false positive) test results caused the university to move classes online. Ninety-five percent of the student population of Rice is vaccinated, including Luu. Slate reached out to Rice University's Crisis Management Team for comment on Luu's experience.

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When patients develop acute respiratory failure, accurately identifying the underlying etiology is essential for determining the best treatment, but it can be challenging to differentiate between common diagnoses in clinical practice. Machine learning models could improve medical diagnosis by augmenting clinical decision making and play a role in the diagnostic evaluation of patients with acute respiratory failure. While machine learning models have been developed to identify common findings on chest radiographs (e.g. pneumonia), augmenting these approaches by also analyzing clinically relevant data from the electronic health record (EHR) could aid in the diagnosis of acute respiratory failure. Machine learning models were trained to predict the cause of acute respiratory failure (pneumonia, heart failure, and/or COPD) using chest radiographs and EHR data from patients within an internal cohort using diagnoses based on physician chart review. Models were also tested on patients in an external cohort using discharge diagnosis codes. A model combining chest radiographs and EHR data outperformed models based on each modality alone for pneumonia and COPD. For pneumonia, the combined model AUROC was 0.79 (0.78-0.79), image model AUROC was 0.73 (0.72-0.75), and EHR model AUROC was 0.73 (0.70-0.76); for COPD, combined: 0.89 (0.83-0.91), image: 0.85 (0.77-0.89), and EHR: 0.80 (0.76-0.84); for heart failure, combined: 0.80 (0.77-0.84), image: 0.77 (0.71-0.81), and EHR: 0.80 (0.75-0.82). In the external cohort, performance was consistent for heart failure and COPD, but declined slightly for pneumonia. Overall, machine learning models combing chest radiographs and EHR data can accurately differentiate between common causes of acute respiratory failure. Further work is needed to determine whether these models could aid clinicians in the diagnosis of acute respiratory failure in clinical settings.

Churn prediction is probably one of the most important applications of data science in the commercial sector. The thing which makes it popular is that its effects are more tangible to comprehend and it plays a major factor in the overall profits earned by the business. Churn is defined in business terms as'when a client cancels a subscription to a service they have been using.' A common example is people cancelling Spotify/Netflix subscriptions. So, Churn Prediction is essentially predicting which clients are most likely to cancel a subscription i.e'leave a company' based on their usage of the service.

Offensive Language detection in social media platforms has been an active field of research over the past years. In non-native English spoken countries, social media users mostly use a code-mixed form of text in their posts/comments. This poses several challenges in the offensive content identification tasks, and considering the low resources available for Tamil, the task becomes much harder. The current study presents extensive experiments using multiple deep learning, and transfer learning models to detect offensive content on YouTube. We propose a novel and flexible approach of selective translation and transliteration techniques to reap better results from fine-tuning and ensembling multilingual transformer networks like BERT, Distil- BERT, and XLM-RoBERTa. The experimental results showed that ULMFiT is the best model for this task. The best performing models were ULMFiT and mBERTBiLSTM for this Tamil code-mix dataset instead of more popular transfer learning models such as Distil- BERT and XLM-RoBERTa and hybrid deep learning models. The proposed model ULMFiT and mBERTBiLSTM yielded good results and are promising for effective offensive speech identification in low-resourced languages.

Our ability to know when to trust the decisions made by machine learning systems has not kept up with the staggering improvements in their performance, limiting their applicability in high-stakes domains. We introduce Prover-Verifier Games (PVGs), a game-theoretic framework to encourage learning agents to solve decision problems in a verifiable manner. The PVG consists of two learners with competing objectives: a trusted verifier network tries to choose the correct answer, and a more powerful but untrusted prover network attempts to persuade the verifier of a particular answer, regardless of its correctness. The goal is for a reliable justification protocol to emerge from this game. We analyze variants of the framework, including simultaneous and sequential games, and narrow the space down to a subset of games which provably have the desired equilibria. We develop instantiations of the PVG for two algorithmic tasks, and show that in practice, the verifier learns a robust decision rule that is able to receive useful and reliable information from an untrusted prover. Importantly, the protocol still works even when the verifier is frozen and the prover's messages are directly optimized to convince the verifier.