Datacenters execute large computational jobs, which are composed of smaller tasks. A job completes when all its tasks finish, so stragglers -- rare, yet extremely slow tasks -- are a major impediment to datacenter performance. Accurately predicting stragglers would enable proactive intervention, allowing datacenter operators to mitigate stragglers before they delay a job. While much prior work applies machine learning to predict computer system performance, these approaches rely on complete labels -- i.e., sufficient examples of all possible behaviors, including straggling and non-straggling -- or strong assumptions about the underlying latency distributions -- e.g., whether Gaussian or not. Within a running job, however, none of this information is available until stragglers have revealed themselves when they have already delayed the job. To predict stragglers accurately and early without labeled positive examples or assumptions on latency distributions, this paper presents NURD, a novel Negative-Unlabeled learning approach with Reweighting and Distribution-compensation that only trains on negative and unlabeled streaming data. The key idea is to train a predictor using finished tasks of non-stragglers to predict latency for unlabeled running tasks, and then reweight each unlabeled task's prediction based on a weighting function of its feature space. We evaluate NURD on two production traces from Google and Alibaba, and find that compared to the best baseline approach, NURD produces 2--11 percentage point increases in the F1 score in terms of prediction accuracy, and 2.0--8.8 percentage point improvements in job completion time.

The most common gynecological disorder affecting women globally is known as polycystic ovary syndrome (PCOS). The symptoms of PCOS include irregular periods, hirsutism, thinning hair and hair loss over head, oily skin or acne and weight gain. PCOS can lead to risk in later life with a lifelong situation that causes a person's blood sugar levels to promote type-II diabetes. High blood pressure and high cholesterol which can lead to heart stroke, overweight ladies may expand sleep apnoea, a situation that causes interrupted breathing at some stage in sleep. Around 10 - 15% of reproductive age (15 to 49 years) of women suffer from this. The monetary expenses of this disease and its comorbidities need the development of instruments and techniques so one can permit for early and precise identification. To cope with this problem this paper proposes a system for the early detection and prediction of PCOS from the most reliable and minimal and promising scientific and metabolic parameters, which is early detection for these diseases. Machine Learning[Shinde and Shah, 2018] can be leveraged to perform prognostication of PCOS that exigently extracts factual records from the given statistics considering the fact that machine learning is better known as glorified statistics. A specific type of machine learning algorithm that seeks to improve the overall performance by combining the predictions from more than one model which is a trendy meta method is known as an Ensemble Learning Approach.

With a rapidly rising number of transients detected in astronomy, classification methods based on machine learning are increasingly being employed. Their goals are typically to obtain a definitive classification of transients, and for good performance they usually require the presence of a large set of observations. However, well-designed, targeted models can reach their classification goals with fewer computing resources. This paper presents SNGuess, a model designed to find young extragalactic nearby transients with high purity. SNGuess works with a set of features that can be efficiently calculated from astronomical alert data. Some of these features are static and associated with the alert metadata, while others must be calculated from the photometric observations contained in the alert. Most of the features are simple enough to be obtained or to be calculated already at the early stages in the lifetime of a transient after its detection. We calculate these features for a set of labeled public alert data obtained over a time span of 15 months from the Zwicky Transient Facility (ZTF). The core model of SNGuess consists of an ensemble of decision trees, which are trained via gradient boosting. Approximately 88% of the candidates suggested by SNGuess from a set of alerts from ZTF spanning from April 2020 to August 2021 were found to be true relevant supernovae (SNe). For alerts with bright detections, this number ranges between 92% and 98%. Since April 2020, transients identified by SNGuess as potential young SNe in the ZTF alert stream are being published to the Transient Name Server (TNS) under the AMPEL_ZTF_NEW group identifier. SNGuess scores for any transient observed by ZTF can be accessed via a web service. The source code of SNGuess is publicly available.

Gradient estimation is often necessary for fitting generative models with discrete latent variables, in contexts such as reinforcement learning and variational autoencoder (VAE) training. The DisARM estimator (Yin et al. 2020; Dong, Mnih, and Tucker 2020) achieves state of the art gradient variance for Bernoulli latent variable models in many contexts. However, DisARM and other estimators have potentially exploding variance near the boundary of the parameter space, where solutions tend to lie. To ameliorate this issue, we propose a new gradient estimator \textit{bitflip}-1 that has lower variance at the boundaries of the parameter space. As bitflip-1 has complementary properties to existing estimators, we introduce an aggregated estimator, \textit{unbiased gradient variance clipping} (UGC) that uses either a bitflip-1 or a DisARM gradient update for each coordinate. We theoretically prove that UGC has uniformly lower variance than DisARM. Empirically, we observe that UGC achieves the optimal value of the optimization objectives in toy experiments, discrete VAE training, and in a best subset selection problem.

This paper examines the use of risk models to predict the timing and location of wildfires caused by electricity infrastructure. Our data include historical ignition and wire-down points triggered by grid infrastructure collected between 2015 to 2019 in Pacific Gas & Electricity territory along with various weather, vegetation, and very high resolution data on grid infrastructure including location, age, materials. With these data we explore a range of machine learning methods and strategies to manage training data imbalance. The best area under the receiver operating characteristic we obtain is 0.776 for distribution feeder ignitions and 0.824 for transmission line wire-down events, both using the histogram-based gradient boosting tree algorithm (HGB) with under-sampling. We then use these models to identify which information provides the most predictive value. After line length, we find that weather and vegetation features dominate the list of top important features for ignition or wire-down risk. Distribution ignition models show more dependence on slow-varying vegetation variables such as burn index, energy release content, and tree height, whereas transmission wire-down models rely more on primary weather variables such as wind speed and precipitation. These results point to the importance of improved vegetation modeling for feeder ignition risk models, and improved weather forecasting for transmission wire-down models. We observe that infrastructure features make small but meaningful improvements to risk model predictive power.

It is inevitably crucial to classify sleep stage for the diagnosis of various diseases. However, existing automated diagnosis methods mostly adopt the "gold-standard" lectroencephalogram (EEG) or other uni-modal sensing signal of the PolySomnoGraphy (PSG) machine in hospital, that are expensive, importable and therefore unsuitable for point-of-care monitoring at home. To enable the sleep stage monitoring at home, in this paper, we analyze the relationship between infrared videos and the EEG signal and propose a new task: to classify the sleep stage using infrared videos by distilling useful knowledge from EEG signals to the visual ones. To establish a solid cross-modal benchmark for this application, we develop a new dataset termed as Seeing your Sleep Stage via Infrared Video and EEG ($S^3VE$). $S^3VE$ is a large-scale dataset including synchronized infrared video and EEG signal for sleep stage classification, including 105 subjects and 154,573 video clips that is more than 1100 hours long. Our contributions are not limited to datasets but also about a novel cross-modal distillation baseline model namely the structure-aware contrastive distillation (SACD) to distill the EEG knowledge to infrared video features. The SACD achieved the state-of-the-art performances on both our $S^3VE$ and the existing cross-modal distillation benchmark. Both the benchmark and the baseline methods will be released to the community. We expect to raise more attentions and promote more developments in the sleep stage classification and more importantly the cross-modal distillation from clinical signal/media to the conventional media.

The multi-class prediction had gained popularity over recent years. Thus measuring fit goodness becomes a cardinal question that researchers often have to deal with. Several metrics are commonly used for this task. However, when one has to decide about the right measurement, he must consider that different use-cases impose different constraints that govern this decision. A leading constraint at least in \emph{real world} multi-class problems is imbalanced data: Multi categorical problems hardly provide symmetrical data. Hence, when we observe common KPIs (key performance indicators), e.g., Precision-Sensitivity or Accuracy, one can seldom interpret the obtained numbers into the model's actual needs. We suggest generalizing Matthew's correlation coefficient into multi-dimensions. This generalization is based on a geometrical interpretation of the generalized confusion matrix.

Several researchers have focused on studying driver cognitive behavior and mental load for in-vehicle interaction while driving. Adaptive interfaces that vary with mental and perceptual load levels could help in reducing accidents and enhancing the driver experience. In this paper, we analyze the effects of mental workload and perceptual load on psychophysiological dimensions and provide a machine learning-based framework for mental and perceptual load estimation in a dual task scenario for in-vehicle interaction (https://github.com/amrgomaaelhady/MWL-PL-estimator). We use off-the-shelf non-intrusive sensors that can be easily integrated into the vehicle's system. Our statistical analysis shows that while mental workload influences some psychophysiological dimensions, perceptual load shows little effect. Furthermore, we classify the mental and perceptual load levels through the fusion of these measurements, moving towards a real-time adaptive in-vehicle interface that is personalized to user behavior and driving conditions. We report up to 89% mental workload classification accuracy and provide a real-time minimally-intrusive solution.

Cancer is a disease that stems from the disruption of cellular state. Through genetic perturbations, tumor cells attain cellular states that give them proliferative advantage over the surrounding normal tissue [1]. The inherent variability of this process has hampered efforts to find highly effective common therapies, thereby ushering the need for precision medicine [2]. The scale of single-cell experiments is poised to revolutionize personalized medicine by effective characterization of the complete heterogeneity within a tumor for each individual patient [3, 4]. Recent expansion of single-cell sequencing technologies has exponentially increased the scale of knowledge attainable through a single biological experiment [5].

This paper proposes a framework based on a causal model of safety upon which effective safety assurance cases for ML-based applications can be developed. In doing so, we build upon established principles of safety engineering as well as previous work on structuring assurance arguments for ML. The paper defines four categories of safety case evidence and a structured analysis approach within which these evidences can be effectively combined. Where appropriate, abstract formalisations of these contributions are used to illustrate the causalities they evaluate, their contributions to the safety argument and desirable properties of the evidences. Based on the proposed framework, progress in this area is re-evaluated and a set of future research directions proposed in order for tangible progress in this field to be made.