Healthcare is an important aspect of human life. Use of technologies in healthcare has increased manifolds after the pandemic. Internet of Things based systems and devices proposed in literature can help elders, children and adults facing/experiencing health problems. This paper exhaustively reviews thirty-nine wearable based datasets which can be used for evaluating the system to recognize Activities of Daily Living and Falls. A comparative analysis on the SisFall dataset using five machine learning methods i.e., Logistic Regression, Linear Discriminant Analysis, K-Nearest Neighbor, Decision Tree and Naive Bayes is performed in python. The dataset is modified in two ways, in first all the attributes present in dataset are used as it is and labelled in binary form. In second, magnitude of three axes(x,y,z) for three sensors value are computed and then used in experiment with label attribute. The experiments are performed on one subject, ten subjects and all the subjects and compared in terms of accuracy, precision and recall. The results obtained from this study proves that KNN outperforms other machine learning methods in terms of accuracy, precision and recall. It is also concluded that personalization of data improves accuracy.

Artificial intelligence (AI) models have been developed to predict clinically relevant biomarkers for colorectal cancer (CRC), including microsatellite instability (MSI). However, existing deep-learning networks are data-hungry and require large training datasets, which are often lacking in the medical domain. In this study, based on the latest Hierarchical Vision Transformer using Shifted Windows (Swin-T), we developed an efficient workflow for biomarkers in CRC (MSI, hypermutation, chromosomal instability, CpG island methylator phenotype, BRAF, and TP53 mutation) that required relatively small datasets, but achieved a state-of-the-art (SOTA) predictive performance. Our Swin-T workflow substantially outperformed published models in an intra-study cross-validation experiment using the TCGA-CRC-DX dataset (N = 462). It also demonstrated excellent generalizability in cross-study external validation and delivered a SOTA AUROC of 0.90 for MSI, using the MCO dataset for training (N = 1065) and the TCGA-CRC-DX for testing. A similar performance (AUROC = 0.91) was achieved by Echle et al., using ~8000 training samples (ResNet18) on the same testing dataset. Swin-T was extremely efficient when using small training datasets and exhibited robust predictive performance with 200-500 training samples. These data indicate that Swin-T could be 5-10 times more efficient than existing algorithms for MSI based on ResNet18 and ShuffleNet. Furthermore, the Swin-T models showed promise as pre-screening tests for MSI status and BRAF mutation status, which could exclude and reduce the samples before subsequent standard testing in a cascading diagnostic workflow, to allow a reduction in turnaround time and costs.

Dementia is a neuropsychiatric brain disorder that usually occurs when one or more brain cells stop working partially or at all. Diagnosis of this disorder in the early phases of the disease is a vital task to rescue patients lives from bad consequences and provide them with better healthcare. Machine learning methods have been proven to be accurate in predicting dementia in the early phases of the disease. The prediction of dementia depends heavily on the type of collected data which usually are gathered from Normalized Whole Brain Volume (nWBV) and Atlas Scaling Factor (ASF) which are normally measured and corrected from Magnetic Resonance Imaging (MRIs). Other biological features such as age and gender can also help in the diagnosis of dementia. Although many studies use machine learning for predicting dementia, we could not reach a conclusion on the stability of these methods for which one is more accurate under different experimental conditions. Therefore, this paper investigates the conclusion stability regarding the performance of machine learning algorithms for dementia prediction. To accomplish this, a large number of experiments were run using 7 machine learning algorithms and two feature reduction algorithms namely, Information Gain (IG) and Principal Component Analysis (PCA). To examine the stability of these algorithms, thresholds of feature selection were changed for the IG from 20% to 100% and the PCA dimension from 2 to 8. This has resulted in 7x9 + 7x7= 112 experiments. In each experiment, various classification evaluation data were recorded. The obtained results show that among seven algorithms the support vector machine and Naive Bayes are the most stable algorithms while changing the selection threshold. Also, it was found that using IG would seem more efficient than using PCA for predicting Dementia.

Cough audio signal classification is a potentially useful tool in screening for respiratory disorders, such as COVID-19. Since it is dangerous to collect data from patients with such contagious diseases, many research teams have turned to crowdsourcing to quickly gather cough sound data, as it was done to generate the COUGHVID dataset. The COUGHVID dataset enlisted expert physicians to diagnose the underlying diseases present in a limited number of uploaded recordings. However, this approach suffers from potential mislabeling of the coughs, as well as notable disagreement between experts. In this work, we use a semi-supervised learning (SSL) approach to improve the labeling consistency of the COUGHVID dataset and the robustness of COVID-19 versus healthy cough sound classification. First, we leverage existing SSL expert knowledge aggregation techniques to overcome the labeling inconsistencies and sparsity in the dataset. Next, our SSL approach is used to identify a subsample of re-labeled COUGHVID audio samples that can be used to train or augment future cough classification models. The consistency of the re-labeled data is demonstrated in that it exhibits a high degree of class separability, 3x higher than that of the user-labeled data, despite the expert label inconsistency present in the original dataset. Furthermore, the spectral differences in the user-labeled audio segments are amplified in the re-labeled data, resulting in significantly different power spectral densities between healthy and COVID-19 coughs, which demonstrates both the increased consistency of the new dataset and its explainability from an acoustic perspective. Finally, we demonstrate how the re-labeled dataset can be used to train a cough classifier. This SSL approach can be used to combine the medical knowledge of several experts to improve the database consistency for any diagnostic classification task.

graph neural networks (GNNs) are the dominant paradigm for modeling and handling graph structure data by learning universal node representation. The traditional way of training GNNs depends on a great many labeled data, which results in high requirements on cost and time. In some special scene, it is even unavailable and impracticable. Self-supervised representation learning, which can generate labels by graph structure data itself, is a potential approach to tackle this problem. And turning to research on self-supervised learning problem for heterogeneous graphs is more challenging than dealing with homogeneous graphs, also there are fewer studies about it. In this paper, we propose a SElfsupervised learning method for heterogeneous graph via Structure Information based on Metapath (SESIM). The proposed model can construct pretext tasks by predicting jump number between nodes in each metapath to improve the representation ability of primary task. In order to predict jump number, SESIM uses data itself to generate labels, avoiding time-consuming manual labeling. Moreover, predicting jump number in each metapath can effectively utilize graph structure information, which is the essential property between nodes. Therefore, SESIM deepens the understanding of models for graph structure. At last, we train primary task and pretext tasks jointly, and use meta-learning to balance the contribution of pretext tasks for primary task. Empirical results validate the performance of SESIM method and demonstrate that this method can improve the representation ability of traditional neural networks on link prediction task and node classification task.

We present the first dataset and evaluation results on a newly defined computational task of trigger warning assignment. Labeled corpus data has been compiled from narrative works hosted on Archive of Our Own (AO3), a well-known fanfiction site. In this paper, we focus on the most frequently assigned trigger type--violence--and define a document-level binary classification task of whether or not to assign a violence trigger warning to a fanfiction, exploiting warning labels provided by AO3 authors. SVM and BERT models trained in four evaluation setups on the corpora we compiled yield $F_1$ results ranging from 0.585 to 0.798, proving the violence trigger warning assignment to be a doable, however, non-trivial task.

This study presents a methodology for anticounterfeiting of Non-Volatile Memory (NVM) chips. In particular, we experimentally demonstrate a generalized methodology for detecting (i) Integrated Circuit (IC) origin, (ii) recycled or used NVM chips, and (iii) identification of used locations (addresses) in the chip. Our proposed methodology inspects latency and variability signatures of Commercial-Off-The-Shelf (COTS) NVM chips. The proposed technique requires low-cycle (~100) pre-conditioning and utilizes Machine Learning (ML) algorithms. We observe different trends in evolution of latency (sector erase or page write) with cycling on different NVM technologies from different vendors. ML assisted approach is utilized for detecting IC manufacturers with 95.1 % accuracy obtained on prepared test dataset consisting of 3 different NVM technologies including 6 different manufacturers (9 types of chips).

Electronic Health Records (EHRs) aggregate diverse information at the patient level, holding a trajectory representative of the evolution of the patient health status throughout time. Although this information provides context and can be leveraged by physicians to monitor patient health and make more accurate prognoses/diagnoses, patient records can contain information from very long time spans, which combined with the rapid generation rate of medical data makes clinical decision making more complex. Patient trajectory modelling can assist by exploring existing information in a scalable manner, and can contribute in augmenting health care quality by fostering preventive medicine practices. We propose a solution to model patient trajectories that combines different types of information and considers the temporal aspect of clinical data. This solution leverages two different architectures: one supporting flexible sets of input features, to convert patient admissions into dense representations; and a second exploring extracted admission representations in a recurrent-based architecture, where patient trajectories are processed in sub-sequences using a sliding window mechanism. The developed solution was evaluated on two different clinical outcomes, unexpected patient readmission and disease progression, using the publicly available MIMIC-III clinical database. The results obtained demonstrate the potential of the first architecture to model readmission and diagnoses prediction using single patient admissions. While information from clinical text did not show the discriminative power observed in other existing works, this may be explained by the need to fine-tune the clinicalBERT model. Finally, we demonstrate the potential of the sequence-based architecture using a sliding window mechanism to represent the input data, attaining comparable performances to other existing solutions.

Machine learning methods must be trusted to make appropriate decisions in real-world environments, even when faced with out-of-distribution (OOD) samples. Many current approaches simply aim to detect OOD examples and alert the user when an unrecognized input is given. However, when the OOD sample significantly overlaps with the training data, a binary anomaly detection is not interpretable or explainable, and provides little information to the user. We propose a new model for OOD detection that makes predictions at varying levels of granularity as the inputs become more ambiguous, the model predictions become coarser and more conservative. Consider an animal classifier that encounters an unknown bird species and a car. Both cases are OOD, but the user gains more information if the classifier recognizes that its uncertainty over the particular species is too large and predicts bird instead of detecting it as OOD. Furthermore, we diagnose the classifiers performance at each level of the hierarchy improving the explainability and interpretability of the models predictions. We demonstrate the effectiveness of hierarchical classifiers for both fine- and coarse-grained OOD tasks.

Airway segmentation is crucial for the examination, diagnosis, and prognosis of lung diseases, while its manual delineation is unduly burdensome. To alleviate this time-consuming and potentially subjective manual procedure, researchers have proposed methods to automatically segment airways from computerized tomography (CT) images. However, some small-sized airway branches (e.g., bronchus and terminal bronchioles) significantly aggravate the difficulty of automatic segmentation by machine learning models. In particular, the variance of voxel values and the severe data imbalance in airway branches make the computational module prone to discontinuous and false-negative predictions. especially for cohorts with different lung diseases. Attention mechanism has shown the capacity to segment complex structures, while fuzzy logic can reduce the uncertainty in feature representations. Therefore, the integration of deep attention networks and fuzzy theory, given by the fuzzy attention layer, should be an escalated solution for better generalization and robustness. This paper presents an efficient method for airway segmentation, comprising a novel fuzzy attention neural network and a comprehensive loss function to enhance the spatial continuity of airway segmentation. The deep fuzzy set is formulated by a set of voxels in the feature map and a learnable Gaussian membership function. Different from the existing attention mechanism, the proposed channel-specific fuzzy attention addresses the issue of heterogeneous features in different channels. Furthermore, a novel evaluation metric is proposed to assess both the continuity and completeness of airway structures. The efficiency, generalization and robustness of the proposed method have been proved by training on normal lung disease while testing on datasets of lung cancer, COVID-19 and pulmonary fibrosis.