Minimally invasive surgeries and related applications demand surgical tool classification and segmentation at the instance level. Surgical tools are similar in appearance and are long, thin, and handled at an angle. The fine-tuning of state-of-the-art (SOTA) instance segmentation models trained on natural images for instrument segmentation has difficulty discriminating instrument classes. Our research demonstrates that while the bounding box and segmentation mask are often accurate, the classification head mis-classifies the class label of the surgical instrument. We present a new neural network framework that adds a classification module as a new stage to existing instance segmentation models. This module specializes in improving the classification of instrument masks generated by the existing model. The module comprises multi-scale mask attention, which attends to the instrument region and masks the distracting background features. We propose training our classifier module using metric learning with arc loss to handle low inter-class variance of surgical instruments. We conduct exhaustive experiments on the benchmark datasets EndoVis2017 and EndoVis2018. We demonstrate that our method outperforms all (more than 18) SOTA methods compared with, and improves the SOTA performance by at least 12 points (20%) on the EndoVis2017 benchmark challenge and generalizes effectively across the datasets.

The epidemiological characteristics and clinical examination methods of thyroid nodules: Thyroid nodules are widespread clinically, and the incidence continues to rise worldwide, with an autopsy study estimating that 50% to 60% of adults may have thyroid nodules (1, 2). High-resolution ultrasound (US) can detect thyroid nodules in 19%- 68% (3) of randomly selected individuals, of which thyroid cancer occurs in 7% to 15% (4). Thyroid cancer is the most common endocrine malignancy in the United States (5) and the fifth most common cancer among women (6). The benign thyroid nodules without surgical indications generally do not require special treatment. In contrast, malignant thyroid nodules should be elective surgical treatment once diagnosed, and neck dissection should be performed if lymph node metastases are present. Some patients need to be treated with Iodine-131 nuclide after the operation (7) and predict the prognosis. Papillary thyroid carcinoma (PTC) is the most common pathological type of thyroid cancer. It usually has a good prognosis, but relapse patients have a poor prognosis. About 10%-15% of PTC will relapse, and recurrent PTC has aggressive characteristics such as extra-thyroid extension (ETE), invasive cell subtypes, lateral neck lymphatic metastasis, resistance to therapy, and distant metastases (8). The challenge for clinicians is to balance treatment approaches so that patients with low-risk or benign thyroid nodules are not over-treated, while patients with high-risk or malignant thyroid nodules need more aggressive therapies. Therefore, the differential diagnosis of thyroid nodules and the risk stratification are essential and helpful for the subsequent individualized treatment.

Accuracy is a measure of how well a model is performing overall. It is the proportion of correct predictions made by the model out of all the predictions made. In other words, it is the number of true positives and true negatives divided by the total number of predictions. Precision is a measure of how accurate the positive predictions of a model are. It is calculated as the ratio of true positives to the sum of true positives and false positives.

Since introducing changes to the New Payments Platform (NPP) to include longer messages as payment descriptions, it has been identified that people are now using it for communication, and in some cases, the system was being used as a targeted form of domestic and family violence. This type of tech-assisted abuse poses new challenges in terms of identification, actions and approaches to rectify this behaviour. Commonwealth Bank of Australia's Artificial Intelligence Labs team (CBA AI Labs) has developed a new system using advances in deep learning models for natural language processing (NLP) to create a powerful abuse detector that periodically scores all the transactions, and identifies cases of high-risk abuse in millions of records. In this paper, we describe the problem of tech-assisted abuse in the context of banking services, outline the developed model and its performance, and the operating framework more broadly.

The complex events observed at the NOvA long-baseline neutrino oscillation experiment contain vital information for understanding the most elusive particles in the standard model. The NOvA detectors observe interactions of neutrinos from the NuMI beam at Fermilab. Associating the particles produced in these interaction events to their source particles, a process known as reconstruction, is critical for accurately measuring key parameters of the standard model. Events may contain several particles, each producing sparse high-dimensional spatial observations, and current methods are limited to evaluating individual particles. To accurately label these numerous, high-dimensional observations, we present a novel neural network architecture that combines the spatial learning enabled by convolutions with the contextual learning enabled by attention. This joint approach, TransformerCVN, simultaneously classifies each event and reconstructs every individual particle's identity. TransformerCVN classifies events with 90\% accuracy and improves the reconstruction of individual particles by 6\% over baseline methods which lack the integrated architecture of TransformerCVN. In addition, this architecture enables us to perform several interpretability studies which provide insights into the network's predictions and show that TransformerCVN discovers several fundamental principles that stem from the standard model.

Machine learning (ML) applications in healthcare are extensively researched, but successful translations to the bedside are scant. Healthcare institutions are establishing frameworks to govern and promote the implementation of accurate, actionable and reliable models that integrate with clinical workflow. Such governance frameworks require an accompanying technical framework to deploy models in a resource efficient manner. Here we present DEPLOYR, a technical framework for enabling real-time deployment and monitoring of researcher created clinical ML models into a widely used electronic medical record (EMR) system. We discuss core functionality and design decisions, including mechanisms to trigger inference based on actions within EMR software, modules that collect real-time data to make inferences, mechanisms that close-the-loop by displaying inferences back to end-users within their workflow, monitoring modules that track performance of deployed models over time, silent deployment capabilities, and mechanisms to prospectively evaluate a deployed model's impact. We demonstrate the use of DEPLOYR by silently deploying and prospectively evaluating twelve ML models triggered by clinician button-clicks in Stanford Health Care's production instance of Epic. Our study highlights the need and feasibility for such silent deployment, because prospectively measured performance varies from retrospective estimates. By describing DEPLOYR, we aim to inform ML deployment best practices and help bridge the model implementation gap.

Pioneers of autonomous vehicles (AVs) promised to revolutionize the driving experience and driving safety. However, milestones in AVs have materialized slower than forecast. Two culprits are (1) the lack of verifiability of proposed state-of-the-art AV components, and (2) stagnation of pursuing next-level evaluations, e.g., vehicle-to-infrastructure (V2I) and multi-agent collaboration. In part, progress has been hampered by: the large volume of software in AVs, the multiple disparate conventions, the difficulty of testing across datasets and simulators, and the inflexibility of state-of-the-art AV components. To address these challenges, we present AVstack, an open-source, reconfigurable software platform for AV design, implementation, test, and analysis. AVstack solves the validation problem by enabling first-of-a-kind trade studies on datasets and physics-based simulators. AVstack solves the stagnation problem as a reconfigurable AV platform built on dozens of open-source AV components in a high-level programming language. We demonstrate the power of AVstack through longitudinal testing across multiple benchmark datasets and V2I-collaboration case studies that explore trade-offs of designing multi-sensor, multi-agent algorithms.

Causal discovery aims to uncover causal structure among a set of variables. Score-based approaches mainly focus on searching for the best Directed Acyclic Graph (DAG) based on a predefined score function. However, most of them are not applicable on a large scale due to the limited searchability. Inspired by the active learning in generative flow networks, we propose a novel approach to learning a DAG from observational data called GFlowCausal. It converts the graph search problem to a generation problem, in which direct edges are added gradually. GFlowCausal aims to learn the best policy to generate high-reward DAGs by sequential actions with probabilities proportional to predefined rewards. We propose a plug-and-play module based on transitive closure to ensure efficient sampling. Theoretical analysis shows that this module could guarantee acyclicity properties effectively and the consistency between final states and fully-connected graphs. We conduct extensive experiments on both synthetic and real datasets, and results show the proposed approach to be superior and also performs well in a large-scale setting.

In the case of an imbalance between positive and negative samples, hard negative mining strategies have been shown to help models learn more subtle differences between positive and negative samples, thus improving recognition performance. However, if too strict mining strategies are promoted in the dataset, there may be a risk of introducing false negative samples. Meanwhile, the implementation of the mining strategy disrupts the difficulty distribution of samples in the real dataset, which may cause the model to over-fit these difficult samples. Therefore, in this paper, we investigate how to trade off the difficulty of the mined samples in order to obtain and exploit high-quality negative samples, and try to solve the problem in terms of both the loss function and the training strategy. The proposed balance loss provides an effective discriminant for the quality of negative samples by combining a self-supervised approach to the loss function, and uses a dynamic gradient modulation strategy to achieve finer gradient adjustment for samples of different difficulties. The proposed annealing training strategy then constrains the difficulty of the samples drawn from negative sample mining to provide data sources with different difficulty distributions for the loss function, and uses samples of decreasing difficulty to train the model. Extensive experiments show that our new descriptors outperform previous state-of-the-art descriptors for patch validation, matching, and retrieval tasks.

Contrastive learning has shown great promise over annotation scarcity problems in the context of medical image segmentation. Existing approaches typically assume a balanced class distribution for both labeled and unlabeled medical images. However, medical image data in reality is commonly imbalanced (i.e., multi-class label imbalance), which naturally yields blurry contours and usually incorrectly labels rare objects. Moreover, it remains unclear whether all negative samples are equally negative. In this work, we present ACTION, an Anatomical-aware ConTrastive dIstillatiON framework, for semi-supervised medical image segmentation. Specifically, we first develop an iterative contrastive distillation algorithm by softly labeling the negatives rather than binary supervision between positive and negative pairs. We also capture more semantically similar features from the randomly chosen negative set compared to the positives to enforce the diversity of the sampled data. Second, we raise a more important question: Can we really handle imbalanced samples to yield better performance? Hence, the key innovation in ACTION is to learn global semantic relationship across the entire dataset and local anatomical features among the neighbouring pixels with minimal additional memory footprint. During the training, we introduce anatomical contrast by actively sampling a sparse set of hard negative pixels, which can generate smoother segmentation boundaries and more accurate predictions. Extensive experiments across two benchmark datasets and different unlabeled settings show that ACTION significantly outperforms the current state-of-the-art semi-supervised methods.