Assessing resection margins is central to pathological specimen evaluation and has profound implications for patient outcomes. Current practice employs physical inking, which is applied variably, and cautery artifacts can obscure the true margin on histological sections. We present a virtual inking network (VIN) that autonomously localizes the surgical cut surface on whole-slide images, reducing reliance on inks and standardizing margin-focused review. VIN uses a frozen foundation model as the feature extractor and a compact two-layer multilayer perceptron trained for patch-level classification of cautery-consistent features. The dataset comprised 120 hematoxylin and eosin (H&E) stained slides from 12 human tonsil tissue blocks, resulting in ~2 TB of uncompressed raw image data, where a board-certified pathologist provided boundary annotations. In blind testing with 20 slides from previously unseen blocks, VIN produced coherent margin overlays that qualitatively aligned with expert annotations across serial sections. Quantitatively, region-level accuracy was ~73.3% across the test set, with errors largely confined to limited areas that did not disrupt continuity of the whole-slide margin map. These results indicate that VIN captures cautery-related histomorphology and can provide a reproducible, ink-free margin delineation suitable for integration into routine digital pathology workflows and for downstream measurement of margin distances.

Time series forecasting relies on predicting future values from historical data, yet most state-of-the-art approaches-including transformer and multilayer perceptron-based models-optimize using Mean Squared Error (MSE), which has two fundamental weaknesses: its point-wise error computation fails to capture temporal relationships, and it does not account for inherent noise in the data. To overcome these limitations, we introduce the Residual-Informed Loss (RI-Loss), a novel objective function based on the Hilbert-Schmidt Independence Criterion (HSIC). RI-Loss explicitly models noise structure by enforcing dependence between the residual sequence and a random time series, enabling more robust, noise-aware representations. Theoretically, we derive the first non-asymptotic HSIC bound with explicit double-sample complexity terms, achieving optimal convergence rates through Bernstein-type concentration inequalities and Rademacher complexity analysis. This provides rigorous guarantees for RI-Loss optimization while precisely quantifying kernel space interactions. Empirically, experiments across eight real-world benchmarks and five leading forecasting models demonstrate improvements in predictive performance, validating the effectiveness of our approach. The code is publicly available at: https://github.com/shang-xl/RI-Loss.

In low-resource languages like Burmese, classification tasks often fine-tune only the final classification layer, keeping pre-trained encoder weights frozen. While Multi-Layer Perceptrons (MLPs) are commonly used, their fixed non-linearity can limit expressiveness and increase computational cost. This work explores Kolmogorov-Arnold Networks (KANs) as alternative classification heads, evaluating Fourier-based FourierKAN, Spline-based EfficientKAN, and Grid-based FasterKAN-across diverse embeddings including TF-IDF, fastText, and multilingual transformers (mBERT, Distil-mBERT). Experimental results show that KAN-based heads are competitive with or superior to MLPs. EfficientKAN with fastText achieved the highest F1-score (0.928), while FasterKAN offered the best trade-off between speed and accuracy. On transformer embeddings, EfficientKAN matched or slightly outperformed MLPs with mBERT (0.917 F1). These findings highlight KANs as expressive, efficient alternatives to MLPs for low-resource language classification.

Industrial surface defect detection (SDD) is critical for ensuring product quality and manufacturing reliability. Due to the diverse shapes and sizes of surface defects, SDD faces two main challenges: intraclass difference and interclass similarity. Existing methods primarily utilize manually designed models, which require extensive trial and error and often struggle to address both challenges effectively. To overcome this, we propose AutoNAD, an automated neural architecture design framework for SDD that jointly searches over convolutions, transformers, and multi-layer perceptrons. This hybrid design enables the model to capture both fine-grained local variations and long-range semantic context, addressing the two key challenges while reducing the cost of manual network design. To support efficient training of such a diverse search space, AutoNAD introduces a cross weight sharing strategy, which accelerates supernet convergence and improves subnet performance. Additionally, a searchable multi-level feature aggregation module (MFAM) is integrated to enhance multi-scale feature learning. Beyond detection accuracy, runtime efficiency is essential for industrial deployment. To this end, AutoNAD incorporates a latency-aware prior to guide the selection of efficient architectures. The effectiveness of AutoNAD is validated on three industrial defect datasets and further applied within a defect imaging and detection platform. Code is available at https://github.com/Yuxi104/AutoNAD.

Accurate state estimation for flexible robotic systems poses significant challenges, particular for platforms with dynamically deforming structures that invalidate rigid-body assumptions. This paper tackles this problem and allows to extend existing rigid-body pose estimation methods to non-rigid systems. Our approach hinges on two core assumptions: first, the elastic properties are captured by an injective deformation-force model, efficiently learned via a Multi-Layer Perceptron; second, we solve the platform's inherently smooth motion using continuous-time B-spline kinematic models. By continuously applying Newton's Second Law, our method establishes a physical link between visually-derived trajectory acceleration and predicted deformation-induced acceleration. We demonstrate that our approach not only enables robust and accurate pose estimation on non-rigid platforms, but that the properly modeled platform physics instigate inertial sensing properties. We demonstrate this feasibility on a simple spring-camera system, and show how it robustly resolves the typically ill-posed problem of metric scale and gravity recovery in monocular visual odometry.

Deterministic Lateral Displacement (DLD) devices are widely used in microfluidics for label-free, size-based separation of particles and cells, with particular promise in isolating circulating tumor cells (CTCs) for early cancer diagnostics. This study focuses on the optimization of DLD design parameters, such as row shift fraction, post size, and gap distance, to enhance the selective isolation of lung cancer cells based on their physical properties. To overcome the challenges of rare CTC detection and reduce reliance on computationally intensive simulations, machine learning models including gradient boosting, k-nearest neighbors, random forest, and multilayer perceptron (MLP) regressors are employed. Trained on a large, numerically validated dataset, these models predict particle trajectories and identify optimal device configurations, enabling high-throughput and cost-effective DLD design. Beyond trajectory prediction, the models aid in isolating critical design variables, offering a systematic, data-driven framework for automated DLD optimization. This integrative approach advances the development of scalable and precise microfluidic systems for cancer diagnostics, contributing to the broader goals of early detection and personalized medicine.

Deep learning (DL) models, despite their remarkable success, remain vulnerable to small input perturbations that can cause erroneous outputs, motivating the recent proposal of probabilistic robustness (PR) as a complementary alternative to adversarial robustness (AR). However, existing PR formulations assume a fixed and known perturbation distribution, an unrealistic expectation in practice. T o address this limitation, we propose non-parametric probabilistic robustness (NPPR), a more practical PR metric that does not rely on any predefined perturbation distribution. F ollowing the non-parametric paradigm in statistical modeling, NPPR learns an optimized perturbation distribution directly from data, enabling conservative PR evaluation under distributional uncertainty. W e further develop an NPPR estimator based on a Gaussian Mixture Model (GMM) with Multilayer Perceptron (MLP) heads and bicubic up-sampling, covering various input-dependent and input-independent perturbation scenarios. Theoretical analyses establish the relationships among AR, PR, and NPPR. Extensive experiments on CIF AR-10, CIF AR-100, and Tiny ImageNet across ResNet18/50, WideResNet50 and VGG16 validate NPPR as a more practical robustness metric, showing up to 40% more conservative (lower) PR estimates compared to assuming those common perturbation distributions used in state-of-the-arts.

We demonstrate how quantum computation can provide non-trivial improvements in the computational and statistical complexity of the perceptron model. We develop two quantum algorithms for perceptron learning. The first algorithm exploits quantum information processing to determine a separating hyperplane using a number of steps sublinear in the number of data points $N$, namely $O(\sqrt{N})$. The second algorithm illustrates how the classical mistake bound of $O(\frac{1}{\gamma^2})$ can be further improved to $O(\frac{1}{\sqrt{\gamma}})$ through quantum means, where $\gamma$ denotes the margin. Such improvements are achieved through the application of quantum amplitude amplification to the version space interpretation of the perceptron model.

It has been a long-standing problem to efficiently learn a halfspace using as few labels as possible in the presence of noise. In this work, we propose an efficient Perceptron-based algorithm for actively learning homogeneous halfspaces under the uniform distribution over the unit sphere.

It has been a long-standing problem to efficiently learn a halfspace using as few labels as possible in the presence of noise.