Deep Learning
Mobile-Friendly Deep Learning for Plant Disease Detection: A Lightweight CNN Benchmark Across 101 Classes of 33 Crops
Kumar, Anand, Monga, Harminder Pal, Brahma, Tapasi, Kalra, Satyam, Sherif, Navas
It is important to develop early detection systems which can accurately detect. The advancement in computer vision techniques has the potential to solve this challenge. We have developed a mobile-friendly solution which can accurately classify 101 plant diseases across 33 crops. We built a comprehensive dataset by combining different datasets, Plant Doc, PlantVillage, and PlantWild, all of which are for the same purpose. We evaluated performance across several lightweight architectures - MobileNetV2, MobileNetV3, MobileNetV3-Large, and EfficientNet-B0, B1 - specifically chosen for their efficiency on resource-constrained devices. The results were promising, with EfficientNet-B1 delivering our best performance at 94.7% classification accuracy. This architecture struck an optimal balance between accuracy and computational efficiency, making it well-suited for real-world deployment on mobile devices.
Ultra-High-Definition Reference-Based Landmark Image Super-Resolution with Generative Diffusion Prior
Shi, Zhenning, Yan, Zizheng, Yu, Yuhang, Xue, Clara, Zhuang, Jingyu, Zhang, Qi, Chen, Jinwei, Li, Tao, Fan, Qingnan
Reference-based Image Super-Resolution (RefSR) aims to restore a low-resolution (LR) image by utilizing the semantic and texture information from an additional reference high-resolution (reference HR) image. Existing diffusion-based RefSR methods are typically built upon ControlNet, which struggles to effectively align the information between the LR image and the reference HR image. Moreover, current RefSR datasets suffer from limited resolution and poor image quality, resulting in the reference images lacking sufficient fine-grained details to support high-quality restoration. To overcome the limitations above, we propose TriFlowSR, a novel framework that explicitly achieves pattern matching between the LR image and the reference HR image. Meanwhile, we introduce Landmark-4K, the first RefSR dataset for Ultra-High-Definition (UHD) landmark scenarios. Considering the UHD scenarios with real-world degradation, in TriFlowSR, we design a Reference Matching Strategy to effectively match the LR image with the reference HR image. Experimental results show that our approach can better utilize the semantic and texture information of the reference HR image compared to previous methods. To the best of our knowledge, we propose the first diffusion-based RefSR pipeline for ultra-high definition landmark scenarios under real-world degradation.
The Knowledge-Reasoning Dissociation: Fundamental Limitations of LLMs in Clinical Natural Language Inference
Jullien, Maรซl, Valentino, Marco, Freitas, Andrรฉ
Large language models are often assumed to acquire increasingly structured, generalizable internal representations simply by scaling data and parameters. We interrogate this assumption by introducing a Clinical Trial Natural Language Inference benchmark comprising four reasoning families, Causal Attribution, Compositional Grounding, Epistemic Verification, and Risk State Abstraction. Each item is paired with a targeted Ground Knowledge and Meta-Level Reasoning Verification (GKMRV) probe, allowing us to dissociate failures of factual access from failures of inference. We evaluate six contemporary LLMs under both direct and chain of thought prompting. Models achieve near-ceiling GKMRV accuracy (mean accuracy 0.918) yet perform poorly on the main reasoning tasks (mean accuracy 0.25). Despite low accuracy, output inferences are highly consistent across samples (mean 0.87), indicating a systematic application of underlying heuristics and shortcuts. These results reveal fundamental structural and representational limitations: current LLMs often possess the relevant clinical knowledge but lack the structured, composable internal representations needed to deploy it reliably (e.g., integrating constraints, weighing evidence, or simulating counterfactuals). Decoupling knowledge from reasoning with GKMRV makes this dissociation explicit and measurable, providing an effective framework for probing the reliability of LLMs in high-stakes domains.
IBEX: Information-Bottleneck-EXplored Coarse-to-Fine Molecular Generation under Limited Data
Xu, Dong, Yang, Zhangfan, Yao, Jenna Xinyi, Song, Shuangbao, Zhu, Zexuan, Ji, Junkai
Three-dimensional generative models increasingly drive structure-based drug discovery, yet it remains constrained by the scarce publicly available protein-ligand complexes. Under such data scarcity, almost all existing pipelines struggle to learn transferable geometric priors and consequently overfit to training-set biases. As such, we present IBEX, an Information-Bottleneck-EXplored coarse-to-fine pipeline to tackle the chronic shortage of protein-ligand complex data in structure-based drug design. Specifically, we use PAC-Bayesian information-bottleneck theory to quantify the information density of each sample. This analysis reveals how different masking strategies affect generalization and indicates that, compared with conventional de novo generation, the constrained Scaffold Hopping task endows the model with greater effective capacity and improved transfer performance. IBEX retains the original TargetDiff architecture and hyperparameters for training to generate molecules compatible with the binding pocket; it then applies an L-BFGS optimization step to finely refine each conformation by optimizing five physics-based terms and adjusting six translational and rotational degrees of freedom in under one second. With only these modifications, IBEX raises the zero-shot docking success rate on CBGBench CrossDocked2020-based from 53% to 64%, improves the mean Vina score from $-7.41 kcal mol^{-1}$ to $-8.07 kcal mol^{-1}$, and achieves the best median Vina energy in 57 of 100 pockets versus 3 for the original TargetDiff. IBEX also increases the QED by 25%, achieves state-of-the-art validity and diversity, and markedly reduces extrapolation error.
AEGIS: Authenticity Evaluation Benchmark for AI-Generated Video Sequences
Li, Jieyu, Zhang, Xin, Zhou, Joey Tianyi
Recent advances in AI-generated content have fueled the rise of highly realistic synthetic videos, posing severe risks to societal trust and digital integrity. Existing benchmarks for video authenticity detection typically suffer from limited realism, insufficient scale, and inadequate complexity, failing to effectively evaluate modern vision-language models against sophisticated forgeries. To address this critical gap, we introduce AEGIS, a novel large-scale benchmark explicitly targeting the detection of hyper-realistic and semantically nuanced AI-generated videos. AEGIS comprises over 10,000 rigorously curated real and synthetic videos generated by diverse, state-of-the-art generative models, including Stable Video Diffusion, CogVideoX-5B, KLing, and Sora, encompassing open-source and proprietary architectures. In particular, AEGIS features specially constructed challenging subsets enhanced with robustness evaluation. Furthermore, we provide multimodal annotations spanning Semantic-Authenticity Descriptions, Motion Features, and Low-level Visual Features, facilitating authenticity detection and supporting downstream tasks such as multimodal fusion and forgery localization. Extensive experiments using advanced vision-language models demonstrate limited detection capabilities on the most challenging subsets of AEGIS, highlighting the dataset's unique complexity and realism beyond the current generalization capabilities of existing models. In essence, AEGIS establishes an indispensable evaluation benchmark, fundamentally advancing research toward developing genuinely robust, reliable, broadly generalizable video authenticity detection methodologies capable of addressing real-world forgery threats. Our dataset is available on https://huggingface.co/datasets/Clarifiedfish/AEGIS.
Modeling Human Responses to Multimodal AI Content
Shen, Zhiqi, Fan, Shaojing, Xu, Danni, Sim, Terence, Kankanhalli, Mohan
As AI-generated content becomes widespread, so does the risk of misinformation. While prior research has primarily focused on identifying whether content is authentic, much less is known about how such content influences human perception and behavior. In domains like trading or the stock market, predicting how people react (e.g., whether a news post will go viral), can be more critical than verifying its factual accuracy. To address this, we take a human-centered approach and introduce the MhAIM Dataset, which contains 154,552 online posts (111,153 of them AI-generated), enabling large-scale analysis of how people respond to AI-generated content. Our human study reveals that people are better at identifying AI content when posts include both text and visuals, particularly when inconsistencies exist between the two. We propose three new metrics: trustworthiness, impact, and openness, to quantify how users judge and engage with online content. We present T-Lens, an LLM-based agent system designed to answer user queries by incorporating predicted human responses to multimodal information. At its core is HR-MCP (Human Response Model Context Protocol), built on the standardized Model Context Protocol (MCP), enabling seamless integration with any LLM. This integration allows T-Lens to better align with human reactions, enhancing both interpretability and interaction capabilities. Our work provides empirical insights and practical tools to equip LLMs with human-awareness capabilities. By highlighting the complex interplay among AI, human cognition, and information reception, our findings suggest actionable strategies for mitigating the risks of AI-driven misinformation.
Memorisation and forgetting in a learning Hopfield neural network: bifurcation mechanisms, attractors and basins
Essex, Adam E., Janson, Natalia B., Norris, Rachel A., Balanov, Alexander G.
Despite explosive expansion of artificial intelligence based on artificial neural networks (ANNs), these are employed as "black boxes'', as it is unclear how, during learning, they form memories or develop unwanted features, including spurious memories and catastrophic forgetting. Much research is available on isolated aspects of learning ANNs, but due to their high dimensionality and non-linearity, their comprehensive analysis remains a challenge. In ANNs, knowledge is thought to reside in connection weights or in attractor basins, but these two paradigms are not linked explicitly. Here we comprehensively analyse mechanisms of memory formation in an 81-neuron Hopfield network undergoing Hebbian learning by revealing bifurcations leading to formation and destruction of attractors and their basin boundaries. We show that, by affecting evolution of connection weights, the applied stimuli induce a pitchfork and then a cascade of saddle-node bifurcations creating new attractors with their basins that can code true or spurious memories, and an abrupt disappearance of old memories (catastrophic forgetting). With successful learning, new categories are represented by the basins of newly born point attractors, and their boundaries by the stable manifolds of new saddles. With this, memorisation and forgetting represent two manifestations of the same mechanism. Our strategy to analyse high-dimensional learning ANNs is universal and applicable to recurrent ANNs of any form. The demonstrated mechanisms of memory formation and of catastrophic forgetting shed light on the operation of a wider class of recurrent ANNs and could aid the development of approaches to mitigate their flaws.
FROGENT: An End-to-End Full-process Drug Design Agent
Pan, Qihua, Xu, Dong, Yao, Jenna Xinyi, Ma, Lijia, Zhu, Zexuan, Ji, Junkai
Powerful AI tools for drug discovery reside in isolated web apps, desktop programs, and code libraries. Such fragmentation forces scientists to manage incompatible interfaces and specialized scripts, which can be a cumbersome and repetitive process. To address this issue, a Full-pROcess druG dEsign ageNT, named FROGENT, has been proposed. Specifically, FROGENT utilizes a Large Language Model and the Model Context Protocol to integrate multiple dynamic biochemical databases, extensible tool libraries, and task-specific AI models. This agentic framework allows FROGENT to execute complicated drug discovery workflows dynamically, including component tasks such as target identification, molecule generation and retrosynthetic planning. FROGENT has been evaluated on eight benchmarks that cover various aspects of drug discovery, such as knowledge retrieval, property prediction, virtual screening, mechanistic analysis, molecular design, and synthesis. It was compared against six increasingly advanced ReAct-style agents that support code execution and literature searches. Empirical results demonstrated that FROGENT triples the best baseline performance in hit-finding and doubles it in interaction profiling, significantly outperforming both the open-source model Qwen3-32B and the commercial model GPT-4o. In addition, real-world cases have been utilized to validate the practicability and generalization of FROGENT. This development suggests that streamlining the agentic drug discovery pipeline can significantly enhance researcher productivity.
Agentic Design Review System
Nag, Sayan, Joseph, K J, Goswami, Koustava, Morariu, Vlad I, Srinivasan, Balaji Vasan
Evaluating graphic designs involves assessing it from multiple facets like alignment, composition, aesthetics and color choices. Evaluating designs in a holistic way involves aggregating feedback from individual expert reviewers. Towards this, we propose an Agentic Design Review System (AgenticDRS), where multiple agents collaboratively analyze a design, orchestrated by a meta-agent. A novel in-context exemplar selection approach based on graph matching and a unique prompt expansion method plays central role towards making each agent design aware. Towards evaluating this framework, we propose DRS-BENCH benchmark. Thorough experimental evaluation against state-of-the-art baselines adapted to the problem setup, backed-up with critical ablation experiments brings out the efficacy of Agentic-DRS in evaluating graphic designs and generating actionable feedback. We hope that this work will attract attention to this pragmatic, yet under-explored research direction.
EgoCross: Benchmarking Multimodal Large Language Models for Cross-Domain Egocentric Video Question Answering
Li, Yanjun, Fu, Yuqian, Qian, Tianwen, Xu, Qi'ao, Dai, Silong, Paudel, Danda Pani, Van Gool, Luc, Wang, Xiaoling
Recent advances in Multimodal Large Language Models (MLLMs) have significantly pushed the frontier of egocentric video question answering (EgocentricQA). However, existing benchmarks and studies are mainly limited to common daily activities such as cooking and cleaning. In contrast, real-world deployment inevitably encounters domain shifts, where target domains differ substantially in both visual style and semantic content. To bridge this gap, we introduce \textbf{EgoCross}, a comprehensive benchmark designed to evaluate the cross-domain generalization of MLLMs in EgocentricQA. EgoCross covers four diverse and challenging domains, including surgery, industry, extreme sports, and animal perspective, representing realistic and high-impact application scenarios. It comprises approximately 1,000 QA pairs across 798 video clips, spanning four key QA tasks: prediction, recognition, localization, and counting. Each QA pair provides both OpenQA and CloseQA formats to support fine-grained evaluation. Extensive experiments show that most existing MLLMs, whether general-purpose or egocentric-specialized, struggle to generalize to domains beyond daily life, highlighting the limitations of current models. Furthermore, we conduct several pilot studies, \eg, fine-tuning and reinforcement learning, to explore potential improvements. We hope EgoCross and our accompanying analysis will serve as a foundation for advancing domain-adaptive, robust egocentric video understanding. Data and codes will be released at: \href{https://github.com/MyUniverse0726/EgoCross}{https://github.com/MyUniverse0726/EgoCross.}