Illegal landfills are posing as a hazardous threat to people all over the world. Due to the arduous nature of manually identifying the location of landfill, many landfills go unnoticed by authorities and later cause dangerous harm to people and environment. Deep learning can play a significant role in identifying these landfills while saving valuable time, manpower and resources. Despite being a burning concern, good quality publicly released datasets for illegal landfill detection are hard to find due to security concerns. However, AerialWaste Dataset is a large collection of 10434 images of Lombardy region of Italy. The images are of varying qualities, collected from three different sources: AGEA Orthophotos, WorldView-3, and Google Earth. The dataset contains professionally curated, diverse and high-quality images which makes it particularly suitable for scalable and impactful research. As we trained several models to compare results, we found complex and heavy models to be prone to overfitting and memorizing training data instead of learning patterns. Therefore, we chose lightweight simpler models which could leverage general features from the dataset. In this study, Mobilenetv2, Googlenet, Densenet, MobileVit and other lightweight deep learning models were used to train and validate the dataset as they achieved significant success with less overfitting. As we saw substantial improvement in the performance using some of these models, we combined the best performing models and came up with an ensemble model. With the help of ensemble and fusion technique, binary classification could be performed on this dataset with 92.33% accuracy, 92.67% precision, 92.33% sensitivity, 92.41% F1 score and 92.71% specificity.

Digital healthcare systems have enabled the collection of mass healthcare data in electronic healthcare records (EHRs), allowing artificial intelligence solutions for various healthcare prediction tasks. However, existing studies often focus on isolated components of EHR data, limiting their predictive performance and interpretability. To address this gap, we propose ProtoEHR, an interpretable hierarchical prototype learning framework that fully exploits the rich, multi-level structure of EHR data to enhance healthcare predictions. More specifically, ProtoEHR models relationships within and across three hierarchical levels of EHRs: medical codes, hospital visits, and patients. We first leverage large language models to extract semantic relationships among medical codes and construct a medical knowledge graph as the knowledge source. Building on this, we design a hierarchical representation learning framework that captures contextualized representations across three levels, while incorporating prototype information within each level to capture intrinsic similarities and improve generalization. To perform a comprehensive assessment, we evaluate ProtoEHR in two public datasets on five clinically significant tasks, including prediction of mortality, prediction of readmission, prediction of length of stay, drug recommendation, and prediction of phenotype. The results demonstrate the ability of ProtoEHR to make accurate, robust, and interpretable predictions compared to baselines in the literature. Furthermore, ProtoEHR offers interpretable insights on code, visit, and patient levels to aid in healthcare prediction.

We introduce a unified framework for learning the spatio-temporal dynamics of vector valued functions by combining operator valued reproducing kernel Hilbert spaces (OV-RKHS) with kernel based Koopman operator methods. The approach enables nonparametric and data driven estimation of complex time evolving vector fields while preserving both spatial and temporal structure. We establish representer theorems for time dependent OV-RKHS interpolation, derive Sobolev type approximation bounds for smooth vector fields, and provide spectral convergence guarantees for kernel Koopman operator approximations. This framework supports efficient reduced order modeling and long term prediction of high dimensional nonlinear systems, offering theoretically grounded tools for forecasting, control, and uncertainty quantification in spatio-temporal machine learning.

Recent strides in pretrained transformer-based language models have propelled state-of-the-art performance in numerous NLP tasks. Yet, as these models grow in size and deployment, their robustness under input perturbations becomes an increasingly urgent question. Existing robustness methods often diverge between small-parameter and large-scale models (LLMs), and they typically rely on labor-intensive, sample-specific adversarial designs. In this paper, we propose a unified, local (sample-level) robustness framework (SALMAN) that evaluates model stability without modifying internal parameters or resorting to complex perturbation heuristics. Central to our approach is a novel Distance Mapping Distortion (DMD) measure, which ranks each sample's susceptibility by comparing input-to-output distance mappings in a near-linear complexity manner. By demonstrating significant gains in attack efficiency and robust training, we position our framework as a practical, model-agnostic tool for advancing the reliability of transformer-based NLP systems.

Single-cell multi-omics data contain huge information of cellular states, and analyzing these data can reveal valuable insights into cellular heterogeneity, diseases, and biological processes. However, as cell differentiation \& development is a continuous and dynamic process, it remains challenging to computationally model and infer cell interaction patterns based on single-cell multi-omics data. This paper presents scI2CL, a new single-cell multi-omics fusion framework based on intra- and inter-omics contrastive learning, to learn comprehensive and discriminative cellular representations from complementary multi-omics data for various downstream tasks. Extensive experiments of four downstream tasks validate the effectiveness of scI2CL and its superiority over existing peers. Concretely, in cell clustering, scI2CL surpasses eight state-of-the-art methods on four widely-used real-world datasets. In cell subtyping, scI2CL effectively distinguishes three latent monocyte cell subpopulations, which are not discovered by existing methods. Simultaneously, scI2CL is the only method that correctly constructs the cell developmental trajectory from hematopoietic stem and progenitor cells to Memory B cells. In addition, scI2CL resolves the misclassification of cell types between two subpopulations of CD4+ T cells, while existing methods fail to precisely distinguish the mixed cells. In summary, scI2CL can accurately characterize cross-omics relationships among cells, thus effectively fuses multi-omics data and learns discriminative cellular representations to support various downstream analysis tasks.

While imaging-genetics holds great promise for unraveling the complex interplay between brain structure and genetic variation in neurological disorders, traditional methods are limited to simplistic linear models or to black-box techniques that lack interpretability. In this paper, we present NeuroPathX, an explainable deep learning framework that uses an early fusion strategy powered by cross-attention mechanisms to capture meaningful interactions between structural variations in the brain derived from MRI and established biological pathways derived from genetics data. To enhance interpretability and robustness, we introduce two loss functions over the attention matrix - a sparsity loss that focuses on the most salient interactions and a pathway similarity loss that enforces consistent representations across the cohort. We validate NeuroPathX on both autism spectrum disorder and Alzheimer's disease. Our results demonstrate that NeuroPathX outperforms competing baseline approaches and reveals biologically plausible associations linked to the disorder. These findings underscore the potential of NeuroPathX to advance our understanding of complex brain disorders. Code is available at https://github.com/jueqiw/NeuroPathX .

Through a controlled study, we identify a systematic deficiency in the multimodal grounding of Vision Language Models (VLMs). While VLMs can recall factual associations when provided a textual reference to an entity; their ability to do so is significantly diminished when the reference is visual instead. Forcing VLMs to rely on image representations of an entity halves their ability to recall factual knowledge, suggesting that VLMs struggle to link their internal knowledge of an entity with its image representation. We show that such linking failures are correlated with the expression of distinct patterns in model internal states, and that probes on these internal states achieve over 92% accuracy at flagging cases where the VLM response is unreliable. These probes can be applied, without retraining, to identify when a VLM will fail to correctly answer a question that requires an understanding of multimodal input. When used to facilitate selective prediction on a visual question answering task, the probes increase coverage by 7.87% (absolute) while also reducing the risk of error by 0.9% (absolute). Addressing the systematic, detectable deficiency is an important avenue in language grounding, and we provide informed recommendations for future directions.

Stroke is the second leading cause of death and the third leading cause of disability worldwide. Clinical guidelines establish diffusion resonance imaging (DWI, ADC) as the standard for localizing, characterizing, and measuring infarct volume, enabling treatment support and prognosis. Nonetheless, such lesion analysis is highly variable due to different patient demographics, scanner vendors, and expert annotations. Computational support approaches have been key to helping with the localization and segmentation of lesions. However, these strategies are dedicated solutions that learn patterns from only one institution, lacking the variability to generalize geometrical lesions shape models. Even worse, many clinical centers lack sufficient labeled samples to adjust these dedicated solutions. This work developed a collaborative framework for segmenting ischemic stroke lesions in DWI sequences by sharing knowledge from deep center-independent representations. From 14 emulated healthcare centers with 2031 studies, the FedAvg model achieved a general DSC of $0.71 \pm 0.24$, AVD of $5.29 \pm 22.74$, ALD of $2.16 \pm 3.60$ and LF1 of $0.70 \pm 0.26$ over all centers, outperforming both the centralized and other federated rules. Interestingly, the model demonstrated strong generalization properties, showing uniform performance across different lesion categories and reliable performance in out-of-distribution centers (with DSC of $0.64 \pm 0.29$ and AVD of $4.44 \pm 8.74$ without any additional training).

The detection of brain tumor in MRI is an important aspect of ensuring timely diagnostics and treatment; however, manual analysis is commonly long and error-prone. Current approaches are not universal because they have limited generalization to heterogeneous tumors, are computationally inefficient, are not interpretable, and lack transparency, thus limiting trustworthiness. To overcome these issues, we introduce MobileDenseAttn, a fusion model of dual streams of MobileNetV2 and DenseNet201 that can help gradually improve the feature representation scale, computing efficiency, and visual explanations via GradCAM. Our model uses feature level fusion and is trained on an augmented dataset of 6,020 MRI scans representing glioma, meningioma, pituitary tumors, and normal samples. Measured under strict 5-fold cross-validation protocols, MobileDenseAttn provides a training accuracy of 99.75%, a testing accuracy of 98.35%, and a stable F1 score of 0.9835 (95% CI: 0.9743 to 0.9920). The extensive validation shows the stability of the model, and the comparative analysis proves that it is a great advancement over the baseline models (VGG19, DenseNet201, MobileNetV2) with a +3.67% accuracy increase and a 39.3% decrease in training time compared to VGG19. The GradCAM heatmaps clearly show tumor-affected areas, offering clinically significant localization and improving interpretability. These findings position MobileDenseAttn as an efficient, high performance, interpretable model with a high probability of becoming a clinically practical tool in identifying brain tumors in the real world.

Large language models have advanced rapidly, but no single model excels in every area -- each has its strengths and weaknesses. Instead of relying on one model alone, we take inspiration from gossip protocols in distributed systems, where information is exchanged with peers until they all come to an agreement. In this setup, models exchange answers and gradually work toward a shared solution. Each LLM acts as a node in a peer-to-peer network, sharing responses and thought processes to reach a collective decision. Our results show that this "gossip-based consensus" leads to robust, resilient, and accurate multi-agent AI reasoning. It helps overcome the weaknesses of individual models and brings out their collective strengths. This approach is similar to how humans build consensus, making AI seem more collaborative and trustworthy instead of just a black-box program.