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GQVis: A Dataset of Genomics Data Questions and Visualizations for Generative AI

arXiv.org Artificial Intelligence

Data visualization is a fundamental tool in genomics research, enabling the exploration, interpretation, and communication of complex genomic features. While machine learning models show promise for transforming data into insightful visualizations, current models lack the training foundation for domain-specific tasks. In an effort to provide a foundational resource for genomics-focused model training, we present a framework for generating a dataset that pairs abstract, low-level questions about genomics data with corresponding visualizations. Building on prior work with statistical plots, our approach adapts to the complexity of genomics data and the specialized representations used to depict them. We further incorporate multiple linked queries and visualizations, along with justifications for design choices, figure captions, and image alt-texts for each item in the dataset. We use genomics data retrieved from three distinct genomics data repositories (4DN, ENCODE, Chromoscope) to produce GQVis: a dataset consisting of 1.14 million single-query data points, 628k query pairs, and 589k query chains. The GQVis dataset and generation code are available at https://huggingface.co/datasets/HIDIVE/GQVis and https://github.com/hms-dbmi/GQVis-Generation.


Generative AI in Heritage Practice: Improving the Accessibility of Heritage Guidance

arXiv.org Artificial Intelligence

This paper discusses the potential for integrating Generative Artificial Intelligence (GenAI) into professional heritage practice with the aim of enhancing the accessibility of public-facing guidance documents. We developed HAZEL, a GenAI chatbot fine-tuned to assist with revising written guidance relating to heritage conservation and interpretation. Using quantitative assessments, we compare HAZEL's performance to that of ChatGPT (GPT-4) in a series of tasks related to the guidance writing process. The results of this comparison indicate a slightly better performance of HAZEL over ChatGPT, suggesting that the GenAI chatbot is more effective once the underlying large language model (LLM) has been fine-tuned. However, we also note significant limitations, particularly in areas requiring cultural sensitivity and more advanced technical expertise. These findings suggest that, while GenAI cannot replace human heritage professionals in technical authoring tasks, its potential to automate and expedite certain aspects of guidance writing could offer valuable benefits to heritage organisations, especially in resource-constrained contexts.


The Mechanistic Emergence of Symbol Grounding in Language Models

arXiv.org Artificial Intelligence

Symbol grounding (Harnad, 1990) describes how symbols such as words acquire their meanings by connecting to real-world sensorimotor experiences. Recent work has shown preliminary evidence that grounding may emerge in (vision-)language models trained at scale without using explicit grounding objectives. Yet, the specific loci of this emergence and the mechanisms that drive it remain largely unexplored. To address this problem, we introduce a controlled evaluation framework that systematically traces how symbol grounding arises within the internal computations through mechanistic and causal analysis. Our findings show that grounding concentrates in middle-layer computations and is implemented through the aggregate mechanism, where attention heads aggregate the environmental ground to support the prediction of linguistic forms. This phenomenon replicates in multimodal dialogue and across architectures (Transformers and state-space models), but not in unidirectional LSTMs. Our results provide behavioral and mechanistic evidence that symbol grounding can emerge in language models, with practical implications for predicting and potentially controlling the reliability of generation.


Confidence-Based Response Abstinence: Improving LLM Trustworthiness via Activation-Based Uncertainty Estimation

arXiv.org Artificial Intelligence

We propose a method for confidence estimation in retrieval-augmented generation (RAG) systems that aligns closely with the correctness of large language model (LLM) outputs. Confidence estimation is especially critical in high-stakes domains such as finance and healthcare, where the cost of an incorrect answer outweighs that of not answering the question. Our approach extends prior uncertainty quantification methods by leveraging raw feed-forward network (FFN) activations as auto-regressive signals, avoiding the information loss inherent in token logits and probabilities after projection and softmax normalization. We model confidence prediction as a sequence classification task, and regularize training with a Huber loss term to improve robustness against noisy supervision. Applied in a real-world financial industry customer-support setting with complex knowledge bases, our method outperforms strong baselines and maintains high accuracy under strict latency constraints. Experiments on Llama 3.1 8B model show that using activations from only the 16th layer preserves accuracy while reducing response latency. Our results demonstrate that activation-based confidence modeling offers a scalable, architecture-aware path toward trustworthy RAG deployment.


NExT-OMNI: Towards Any-to-Any Omnimodal Foundation Models with Discrete Flow Matching

arXiv.org Artificial Intelligence

Next-generation multimodal foundation models capable of any-to-any cross-modal generation and multi-turn interaction will serve as core components of artificial general intelligence systems, playing a pivotal role in human-machine interaction. However, most existing multimodal models remain constrained by autoregressive architectures, whose inherent limitations prevent a balanced integration of understanding and generation capabilities. Although hybrid and decoupling strategies have been explored to address these tasks within unified frameworks separately, their redundant, non-integrated designs limit their applicability to broader scenarios, such as cross-modal retrieval. In this work, we introduce NExT-OMNI, an open-source omnimodal foundation model that achieves unified modeling through discrete flow paradigms. By leveraging metric-induced probability paths and kinetic optimal velocities, NExT-OMNI natively supports any-to-any understanding and generation with enhanced response efficiency, while enabling broader application scenarios through concise unified representations rather than task-decoupled designs. Trained on large-scale interleaved text, image, video, and audio data, NExT-OMNI delivers competitive performance on multimodal generation and understanding benchmarks, while outperforming prior unified models in multi-turn multimodal interaction and cross-modal retrieval, highlighting its architectural advantages as a next-generation multimodal foundation model. To advance further research, we release training details, data protocols, and open-source both the code and model checkpoints.


Training LLM Agents to Empower Humans

arXiv.org Artificial Intelligence

Assistive agents should not only take actions on behalf of a human, but also step out of the way and cede control when there are important decisions to be made. However, current methods for building assistive agents, whether via mimicking expert humans or via RL finetuning on an inferred reward, often encourage agents to complete tasks on their own rather than truly assisting the human attain their objectives. Additionally, these methods often require costly explicit human feedback to provide a training signal. We propose a new approach to tuning assistive language models based on maximizing the human's empowerment, their ability to effect desired changes in the environment. Our empowerment-maximizing method, Empower, only requires offline text data, providing a self-supervised method for fine-tuning language models to better assist humans. To study the efficacy of our approach, we conducted an 18-person user study comparing our empowerment assistant with a strong baseline. Participants preferred our assistant 78% of the time (p=0.015), with a 31% higher acceptance rate and 38% fewer suggestions. Additionally, we introduce a new environment for evaluating multi-turn code assistance using simulated humans. Using this environment, we show that agents trained with Empower increase the success rate of a simulated human programmer on challenging coding questions by an average of 192% over an SFT baseline. With this empowerment objective, we provide a framework for useful aligned AI agents at scale using only offline data without the need for any additional human feedback or verifiable rewards.


A Methodology for Assessing the Risk of Metric Failure in LLMs Within the Financial Domain

arXiv.org Artificial Intelligence

As Generative Artificial Intelligence is adopted across the financial services industry, a significant barrier to adoption and usage is measuring model performance. Historical machine learning metrics can oftentimes fail to generalize to GenAI workloads and are often supplemented using Subject Matter Expert (SME) Evaluation. Even in this combination, many projects fail to account for various unique risks present in choosing specific metrics. Additionally, many widespread benchmarks created by foundational research labs and educational institutions fail to generalize to industrial use. This paper explains these challenges and provides a Risk Assessment Framework to allow for better application of SME and machine learning Metrics


Evaluating Arabic Large Language Models: A Survey of Benchmarks, Methods, and Gaps

arXiv.org Artificial Intelligence

This survey provides the first systematic review of Arabic LLM benchmarks, analyzing 40+ evaluation benchmarks across NLP tasks, knowledge domains, cultural understanding, and specialized capabilities. We propose a taxonomy organizing benchmarks into four categories: Knowledge, NLP Tasks, Culture and Dialects, and Target-Specific evaluations. Our analysis reveals significant progress in benchmark diversity while identifying critical gaps: limited temporal evaluation, insufficient multi-turn dialogue assessment, and cultural misalignment in translated datasets. We examine three primary approaches: native collection, translation, and synthetic generation discussing their trade-offs regarding authenticity, scale, and cost. This work serves as a comprehensive reference for Arabic NLP researchers, providing insights into benchmark methodologies, reproducibility standards, and evaluation metrics while offering recommendations for future development.


CoT-Evo: Evolutionary Distillation of Chain-of-Thought for Scientific Reasoning

arXiv.org Artificial Intelligence

While chain-of-thought (CoT) distillation from advanced large language models (LLMs) has proven effective in general reasoning tasks, it struggles in scientific domains where even advanced models often produce incorrect or superficial reasoning due to high complexity and specialized knowledge requirements. Directly distilling from such flawed outputs results in low-quality training data and limits the performance of smaller student models. To overcome this, we propose CoT-Evo, an evolutionary CoT distillation framework. It begins by constructing a diverse pool of reasoning trajectories from multiple LLM thinkers, enriches them with automatically retrieved domain knowledge, and iteratively refines the trajectories using novelty-driven selection, reflective recombination and mutation. The refinement is guided by a fitness function that evaluates answer correctness, coherence, and effective knowledge utilization. This results in a high-quality CoT dataset tailored for scientific reasoning. We employ this evolved dataset to fine-tune a compact model, which achieves state-of-the-art performance on scientific reasoning benchmarks. Our work establishes a scalable approach to synthesizing high-fidelity scientific reasoning data from diverse and fallible LLMs.


O-Forge: An LLM + Computer Algebra Framework for Asymptotic Analysis

arXiv.org Artificial Intelligence

Large language models have recently demonstrated advanced capabilities in solving IMO and Putnam problems; yet their role in research mathematics has remained fairly limited. The key difficulty is verification: suggested proofs may look plausible, but cannot be trusted without rigorous checking. We present a framework, called LLM+CAS, and an associated tool, O-Forge, that couples frontier LLMs with a computer algebra systems (CAS) in an In-Context Symbolic Feedback loop to produce proofs that are both creative and symbolically verified. Our focus is on asymptotic inequalities, a topic that often involves difficult proofs and appropriate decomposition of the domain into the "right" subdomains. Many mathematicians, including Terry Tao, have suggested that using AI tools to find the right decompositions can be very useful for research-level asymptotic analysis. In this paper, we show that our framework LLM+CAS turns out to be remarkably effective at proposing such decompositions via a combination of a frontier LLM and a CAS. More precisely, we use an LLM to suggest domain decomposition, and a CAS (such as Mathematica) that provides a verification of each piece axiomatically. Using this loop, we answer a question posed by Terence Tao: whether LLMs coupled with a verifier can be used to help prove intricate asymptotic inequalities. More broadly, we show how AI can move beyond contest math towards research-level tools for professional mathematicians.