Large-scale pre-trained machine learning models have reshaped our understanding of artificial intelligence across numerous domains, including our own field of geography. As with any new technology, trust has taken on an important role in this discussion. In this chapter, we examine the multifaceted concept of trust in foundation models, particularly within a geographic context. As reliance on these models increases and they become relied upon for critical decision-making, trust, while essential, has become a fractured concept. Here we categorize trust into three types: epistemic trust in the training data, operational trust in the model's functionality, and interpersonal trust in the model developers. Each type of trust brings with it unique implications for geographic applications. Topics such as cultural context, data heterogeneity, and spatial relationships are fundamental to the spatial sciences and play an important role in developing trust. The chapter continues with a discussion of the challenges posed by different forms of biases, the importance of transparency and explainability, and ethical responsibilities in model development. Finally, the novel perspective of geographic information scientists is emphasized with a call for further transparency, bias mitigation, and regionally-informed policies. Simply put, this chapter aims to provide a conceptual starting point for researchers, practitioners, and policy-makers to better understand trust in (generative) GeoAI.

Multi turn intent understanding is central to task oriented chatbots, yet real deployments face tight token budgets and noisy contexts, and most retrieval pipelines emphasize relevance while overlooking set level diversity and confounds such as more context or exemplar order. We ask whether retrieval diversity, rather than longer prompts, systematically improves LLM intent understanding under fixed budgets. We present a diversity aware retrieval framework that selects in context exemplars to balance intent coverage and linguistic variety, and integrates this selection with standard LLM decoders; the evaluation enforces budget matched prompts and randomized positions, and includes sensitivity analyses over exemplar count, diversity strength, and backbone size. On MultiWOZ 2.4 and SGD, the approach achieves strong gains in Joint Goal Accuracy under equal token budgets, surpassing strong LLM/DST baselines, with consistent improvements across K from 4 to 7 and moderate latency. Overall, the study isolates and validates the impact of content diversity in retrieval and offers a simple, deployable selection principle for building accurate, budget constrained multi turn intent systems.

AI is transforming medical practice and redefining the competencies that future healthcare professionals need to master. Despite international recommendations, the integration of AI into Medicine curricula in Spain had not been systematically evaluated until now. A cross-sectional study (July-September 2025) including Spanish universities offering the official degree in Medicine, according to the 'Register of Universities, Centers and Degrees (Registro de Universidades, Centros y Títulos RUCT)'. Curricula and publicly available institutional documentation were reviewed to identify courses and competencies related to AI in the 2025-2026 academic year. The analysis was performed using descriptive statistics. Of the 52 universities analyzed, ten (19.2%) offer specific AI courses, whereas 36 (69.2%) include no related content. Most of the identified courses are elective, with a credit load ranging from three to six ECTS, representing on average 1.17% of the total 360 credits of the degree. The University of Jaén is the only institution offering a compulsory course with AI content. The territorial analysis reveals marked disparities: Andalusia leads with 55.5% of its universities incorporating AI training, while several communities lack any initiative in this area. The integration of AI into the medical degree in Spain is incipient, fragmented, and uneven, with a low weight in ECTS. The limited training load and predominance of elective courses restrict the preparation of future physicians to practice in a healthcare environment increasingly mediated by AI. The findings support the establishment of minimum standards and national monitoring of indicators.

W e present UniRL-Zero, a unified reinforcement learning (RL) framework that boosts, multimodal language model understanding and reasoning, diffusion model multimedia generation, and their beneficial interaction capabilities within a unified model. Our work defines six scenarios for unified model reinforcement learning, providing systematic baselines for reinforcement learning of unified understanding and generation model. Our code is available at https://github.com/G-UN/UniRL.

Determining crystal structures from X-ray diffraction data is fundamental across diverse scientific fields, yet remains a significant challenge when data is limited to low resolution. While recent deep learning models have made breakthroughs in solving the crystallographic phase problem, the resulting low-resolution electron density maps are often ambiguous and difficult to interpret. To overcome this critical bottleneck, we introduce XDXD, to our knowledge, the first end-to-end deep learning framework to determine a complete atomic model directly from low-resolution single-crystal X-ray diffraction data. Our diffusion-based generative model bypasses the need for manual map interpretation, producing chemically plausible crystal structures conditioned on the diffraction pattern. We demonstrate that XDXD achieves a 70.4\% match rate for structures with data limited to 2.0~Å resolution, with a root-mean-square error (RMSE) below 0.05. Evaluated on a benchmark of 24,000 experimental structures, our model proves to be robust and accurate. Furthermore, a case study on small peptides highlights the model's potential for extension to more complex systems, paving the way for automated structure solution in previously intractable cases.

Retrieval-augmented generation (RAG) has shown some success in augmenting large language models (LLMs) with external knowledge. However, as a non-parametric knowledge integration paradigm for LLMs, RAG methods heavily rely on external retrieval modules and the retrieved textual context prior. Especially for very large scale knowledge augmentation, they would introduce substantial inference latency due to expensive searches and much longer relevant context. In this paper, we propose a parametric knowledge integration method, called \textbf{AtlasKV}, a scalable, effective, and general way to augment LLMs with billion-scale knowledge graphs (KGs) (e.g. 1B triples) using very little GPU memory cost (e.g. less than 20GB VRAM). In AtlasKV, we introduce KG2KV and HiKVP to integrate KG triples into LLMs at scale with sub-linear time and memory complexity. It maintains strong knowledge grounding and generalization performance using the LLMs' inherent attention mechanism, and requires no external retrievers, long context priors, or retraining when adapting to new knowledge.

Reliable verifiable data has become a key driver of capability gains in modern language models, enabling stable reinforcement learning with verifiable rewards and effective distillation that transfers competence across math, coding, and agentic tasks. Yet constructing generalizable synthetic verifiable data remains difficult due to hallucination-prone generation, and weak or trivial verification artifacts that fail to separate strong from weak solutions. Existing approaches often rely on task-specific heuristics or post-hoc filters that do not transfer across domains and lack a principled, universal evaluator of verifiability. In this work, we introduce an evolutionary, task-agnostic, strategy-guided, executably-checkable data synthesis framework that, from minimal seed supervision, jointly synthesizes problems, diverse candidate solutions, and verification artifacts, and iteratively discovers strategies via a consistency-based evaluator that enforces agreement between human-annotated and strategy-induced checks. This pipeline upgrades filtering into principled synthesis: it reliably assembles coherent, verifiable training instances and generalizes without domain-specific rules. Our experiments demonstrate the effectiveness of the proposed approach under both RLVR and model distillation training paradigms. The results show that training with our synthesized data yields significant improvements on both the LiveCodeBench and AgentBench-OS tasks, highlighting the robust generalization of our framework.

This paper presents a comprehensive comparative analysis of Natural Language Processing (NLP) methods for automated toxicity detection in online gaming chats. Traditional machine learning models with embeddings, large language models (LLMs) with zero-shot and few-shot prompting, fine-tuned transformer models, and retrieval-augmented generation (RAG) approaches are evaluated. The evaluation framework assesses three critical dimensions: classification accuracy, processing speed, and computational costs. A hybrid moderation system architecture is proposed that optimizes human moderator workload through automated detection and incorporates continuous learning mechanisms. The experimental results demonstrate significant performance variations across methods, with fine-tuned DistilBERT achieving optimal accuracy-cost trade-offs. The findings provide empirical evidence for deploying cost-effective, efficient content moderation systems in dynamic online gaming environments.

Recent advances in enhancing the reasoning ability of large language models (LLMs) have been remarkably successful. LLMs trained with reinforcement learning (RL) for reasoning demonstrate strong performance in challenging tasks such as mathematics and coding, even with relatively small model sizes. However, despite these improvements in task accuracy, the assessment of creativity in LLM generations has been largely overlooked in reasoning tasks, in contrast to writing tasks. The lack of research on creativity assessment in reasoning primarily stems from two challenges: (1) the difficulty of defining the range of creativity, and (2) the necessity of human evaluation in the assessment process. To address these challenges, we propose CLAWS, a method that defines and classifies mathematical solutions into typical, creative, and hallucinated categories without human evaluation, by leveraging attention weights across prompt sections and output. CLAWS outperforms five existing white-box detection methods (Perplexity, Logit Entropy, Window Entropy, Hidden Score, and Attention Score) on five 7-8B math RL models (DeepSeek, Qwen, Mathstral, OpenMath2, and Oreal). We validate CLAWS on 4545 math problems collected from 181 math contests (AJHSME, AMC, AIME).

The dynamics of tumor-immune interactions within a complex tumor microenvironment are typically modeled using a system of ordinary differential equations or partial differential equations. These models introduce some unknown parameters that need to be estimated accurately and efficiently from the limited and noisy experimental data. Moreover, due to the intricate biological complexity and limitations in experimental measurements, tumor-immune dynamics are not fully understood, and therefore, only partial knowledge of the underlying physics may be available, resulting in unknown or missing terms within the system of equations. In this study, we develop a cancer biology-informed neural network model(CBINN) to infer the unknown parameters in the system of equations as well as to discover the missing physics from sparse and noisy measurements. We test the performance of the CBINN model on three distinct nonlinear compartmental tumor-immune models and evaluate its robustness across multiple synthetic noise levels. By harnessing these highly nonlinear dynamics, our CBINN framework effectively estimates the unknown model parameters and uncovers the underlying physical laws or mathematical structures that govern these biological systems, even from scattered and noisy measurements. The models chosen here represent the dynamic patterns commonly observed in compartmental models of tumor-immune interactions, thereby validating the generalizability and efficacy of our methodology.