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Improvement of a Prediction Model for Heart Failure Survival through Explainable Artificial Intelligence

arXiv.org Artificial Intelligence

Cardiovascular diseases and their associated disorder of heart failure are one of the major death causes globally, being a priority for doctors to detect and predict its onset and medical consequences. Artificial Intelligence (AI) allows doctors to discover clinical indicators and enhance their diagnosis and treatments. Specifically, explainable AI offers tools to improve the clinical prediction models that experience poor interpretability of their results. This work presents an explainability analysis and evaluation of a prediction model for heart failure survival by using a dataset that comprises 299 patients who suffered heart failure. The model employs a data workflow pipeline able to select the best ensemble tree algorithm as well as the best feature selection technique. Moreover, different post-hoc techniques have been used for the explainability analysis of the model. The paper's main contribution is an explainability-driven approach to select the best prediction model for HF survival based on an accuracy-explainability balance. Therefore, the most balanced explainable prediction model implements an Extra Trees classifier over 5 selected features (follow-up time, serum creatinine, ejection fraction, age and diabetes) out of 12, achieving a balanced-accuracy of 85.1% and 79.5% with cross-validation and new unseen data respectively. The follow-up time is the most influencing feature followed by serum-creatinine and ejection-fraction. The explainable prediction model for HF survival presented in this paper would improve a further adoption of clinical prediction models by providing doctors with intuitions to better understand the reasoning of, usually, black-box AI clinical solutions, and make more reasonable and data-driven decisions.


Spatio-Temporal Split Learning for Privacy-Preserving Medical Platforms: Case Studies with COVID-19 CT, X-Ray, and Cholesterol Data

arXiv.org Artificial Intelligence

Machine learning requires a large volume of sample data, especially when it is used in high-accuracy medical applications. However, patient records are one of the most sensitive private information that is not usually shared among institutes. This paper presents spatio-temporal split learning, a distributed deep neural network framework, which is a turning point in allowing collaboration among privacy-sensitive organizations. Our spatio-temporal split learning presents how distributed machine learning can be efficiently conducted with minimal privacy concerns. The proposed split learning consists of a number of clients and a centralized server. Each client has only has one hidden layer, which acts as the privacy-preserving layer, and the centralized server comprises the other hidden layers and the output layer. Since the centralized server does not need to access the training data and trains the deep neural network with parameters received from the privacy-preserving layer, privacy of original data is guaranteed. We have coined the term, spatio-temporal split learning, as multiple clients are spatially distributed to cover diverse datasets from different participants, and we can temporally split the learning process, detaching the privacy preserving layer from the rest of the learning process to minimize privacy breaches. This paper shows how we can analyze the medical data whilst ensuring privacy using our proposed multi-site spatio-temporal split learning algorithm on Coronavirus Disease-19 (COVID-19) chest Computed Tomography (CT) scans, MUsculoskeletal RAdiographs (MURA) X-ray images, and cholesterol levels.


One Chatbot Per Person: Creating Personalized Chatbots based on Implicit User Profiles

arXiv.org Artificial Intelligence

Personalized chatbots focus on endowing chatbots with a consistent personality to behave like real users, give more informative responses, and further act as personal assistants. Existing personalized approaches tried to incorporate several text descriptions as explicit user profiles. However, the acquisition of such explicit profiles is expensive and time-consuming, thus being impractical for large-scale real-world applications. Moreover, the restricted predefined profile neglects the language behavior of a real user and cannot be automatically updated together with the change of user interests. In this paper, we propose to learn implicit user profiles automatically from large-scale user dialogue history for building personalized chatbots. Specifically, leveraging the benefits of Transformer on language understanding, we train a personalized language model to construct a general user profile from the user's historical responses. To highlight the relevant historical responses to the input post, we further establish a key-value memory network of historical post-response pairs, and build a dynamic post-aware user profile. The dynamic profile mainly describes what and how the user has responded to similar posts in history. To explicitly utilize users' frequently used words, we design a personalized decoder to fuse two decoding strategies, including generating a word from the generic vocabulary and copying one word from the user's personalized vocabulary. Experiments on two real-world datasets show the significant improvement of our model compared with existing methods.


Data-driven Smart Ponzi Scheme Detection

arXiv.org Artificial Intelligence

Tóm tắt nội dung--A smart Ponzi scheme is a new form of economic crime that uses Ethereum smart contract account and cryptocurrency to implement Ponzi scheme. The smart Ponzi scheme has harmed the interests of many investors, but researches on smart Ponzi scheme detection is still very limited. The existing smart Ponzi scheme detection methods have the problems of requiring many human resources in feature engineering and poor model portability. To solve these problems, we propose a datadriven smart Ponzi scheme detection system in this paper. The system uses dynamic graph embedding technology to automatically learn the representation of an account based on multi-source and multi-modal data related to account transactions. Compared with traditional methods, the proposed system requires very limited human-computer interaction. To the best of our knowledge, this is the first work to implement smart Ponzi scheme detection through dynamic graph embedding. Ponzi schemes require a constant flow of funds from new investors. The detection method based on source contributed by new investors to pay off the returns of existing code inspection detects the smart Ponzi scheme by manually investors (Figure 1).


An Empirical Cybersecurity Evaluation of GitHub Copilot's Code Contributions

arXiv.org Artificial Intelligence

There is burgeoning interest in designing AI-based systems to assist humans in designing computing systems, including tools that automatically generate computer code. The most notable of these comes in the form of the first self-described `AI pair programmer', GitHub Copilot, a language model trained over open-source GitHub code. However, code often contains bugs - and so, given the vast quantity of unvetted code that Copilot has processed, it is certain that the language model will have learned from exploitable, buggy code. This raises concerns on the security of Copilot's code contributions. In this work, we systematically investigate the prevalence and conditions that can cause GitHub Copilot to recommend insecure code. To perform this analysis we prompt Copilot to generate code in scenarios relevant to high-risk CWEs (e.g. those from MITRE's "Top 25" list). We explore Copilot's performance on three distinct code generation axes -- examining how it performs given diversity of weaknesses, diversity of prompts, and diversity of domains. In total, we produce 89 different scenarios for Copilot to complete, producing 1,692 programs. Of these, we found approximately 40% to be vulnerable.


Open Relation Modeling: Learning to Define Relations between Entities

arXiv.org Artificial Intelligence

Relations between entities can be represented by different instances, e.g., a sentence containing both entities or a fact in a Knowledge Graph (KG). However, these instances may not well capture the general relations between entities, may be difficult to understand by humans, even may not be found due to the incompleteness of the knowledge source. In this paper, we introduce the Open Relation Modeling task - given two entities, generate a coherent sentence describing the relation between them. To solve this task, we propose to teach machines to generate definition-like relation descriptions by letting them learn from definitions of entities. Specifically, we fine-tune Pre-trained Language Models (PLMs) to produce definitions conditioned on extracted entity pairs. To help PLMs reason between entities and provide additional relational knowledge to PLMs for open relation modeling, we incorporate reasoning paths in KGs and include a reasoning path selection mechanism. We show that PLMs can select interpretable and informative reasoning paths by confidence estimation, and the selected path can guide PLMs to generate better relation descriptions. Experimental results show that our model can generate concise but informative relation descriptions that capture the representative characteristics of entities and relations.


Quantization Backdoors to Deep Learning Models

arXiv.org Artificial Intelligence

There is currently a burgeoning demand for deploying deep learning (DL) models on ubiquitous edge Internet of Things devices attributing to their low latency and high privacy preservation. However, DL models are often large in size and require large-scale computation, which prevents them from being placed directly onto IoT devices where resources are constrained and 32-bit floating-point operations are unavailable. Model quantization is a pragmatic solution, which enables DL deployment on mobile devices and embedded systems by effortlessly post-quantizing a large high-precision model into a small low-precision model while retaining the model inference accuracy. This work reveals that the standard quantization operation can be abused to activate a backdoor. We demonstrate that a full-precision backdoored model that does not have any backdoor effect in the presence of a trigger -- as the backdoor is dormant -- can be activated by the default TensorFlow-Lite quantization, the only product-ready quantization framework to date. We ascertain that all trained float-32 backdoored models exhibit no backdoor effect even in the presence of trigger inputs. State-of-the-art frontend detection approaches, such as Neural Cleanse and STRIP, fail to identify the backdoor in the float-32 models. When each of the float-32 models is converted into an int-8 format model through the standard TFLite post-training quantization, the backdoor is activated in the quantized model, which shows a stable attack success rate close to 100% upon inputs with the trigger, while behaves normally upon non-trigger inputs. This work highlights that a stealthy security threat occurs when end users utilize the on-device post-training model quantization toolkits, informing security researchers of cross-platform overhaul of DL models post quantization even if they pass frontend inspections.


VAE-CE: Visual Contrastive Explanation using Disentangled VAEs

arXiv.org Artificial Intelligence

The goal of a classification model is to assign the correct labels to data. In most cases, this data is not fully described by the given set of labels. Often a rich set of meaningful concepts exist in the domain that can much more precisely describe each datapoint. Such concepts can also be highly useful for interpreting the model's classifications. In this paper we propose a model, denoted as Variational Autoencoder-based Contrastive Explanation (VAE-CE), that represents data with high-level concepts and uses this representation for both classification and generating explanations. The explanations are produced in a contrastive manner, conveying why a datapoint is assigned to one class rather than an alternative class. An explanation is specified as a set of transformations of the input datapoint, with each step depicting a concept changing towards the contrastive class. We build the model using a disentangled VAE, extended with a new supervised method for disentangling individual dimensions. An analysis on synthetic data and MNIST shows that the approaches to both disentanglement and explanation provide benefits over other methods.


Reinforcement Learning to Optimize Lifetime Value in Cold-Start Recommendation

arXiv.org Artificial Intelligence

Recommender system plays a crucial role in modern E-commerce platform. Due to the lack of historical interactions between users and items, cold-start recommendation is a challenging problem. In order to alleviate the cold-start issue, most existing methods introduce content and contextual information as the auxiliary information. Nevertheless, these methods assume the recommended items behave steadily over time, while in a typical E-commerce scenario, items generally have very different performances throughout their life period. In such a situation, it would be beneficial to consider the long-term return from the item perspective, which is usually ignored in conventional methods. Reinforcement learning (RL) naturally fits such a long-term optimization problem, in which the recommender could identify high potential items, proactively allocate more user impressions to boost their growth, therefore improve the multi-period cumulative gains. Inspired by this idea, we model the process as a Partially Observable and Controllable Markov Decision Process (POC-MDP), and propose an actor-critic RL framework (RL-LTV) to incorporate the item lifetime values (LTV) into the recommendation. In RL-LTV, the critic studies historical trajectories of items and predict the future LTV of fresh item, while the actor suggests a score-based policy which maximizes the future LTV expectation. Scores suggested by the actor are then combined with classical ranking scores in a dual-rank framework, therefore the recommendation is balanced with the LTV consideration. Our method outperforms the strong live baseline with a relative improvement of 8.67% and 18.03% on IPV and GMV of cold-start items, on one of the largest E-commerce platform.


Single Underwater Image Enhancement Using an Analysis-Synthesis Network

arXiv.org Artificial Intelligence

Most deep models for underwater image enhancement resort to training on synthetic datasets based on underwater image formation models. Although promising performances have been achieved, they are still limited by two problems: (1) existing underwater image synthesis models have an intrinsic limitation, in which the homogeneous ambient light is usually randomly generated and many important dependencies are ignored, and thus the synthesized training data cannot adequately express characteristics of real underwater environments; (2) most of deep models disregard lots of favorable underwater priors and heavily rely on training data, which extensively limits their application ranges. To address these limitations, a new underwater synthetic dataset is first established, in which a revised ambient light synthesis equation is embedded. The revised equation explicitly defines the complex mathematical relationship among intensity values of the ambient light in RGB channels and many dependencies such as surface-object depth, water types, etc, which helps to better simulate real underwater scene appearances. Secondly, a unified framework is proposed, named ANA-SYN, which can effectively enhance underwater images under collaborations of priors (underwater domain knowledge) and data information (underwater distortion distribution). The proposed framework includes an analysis network and a synthesis network, one for priors exploration and another for priors integration. To exploit more accurate priors, the significance of each prior for the input image is explored in the analysis network and an adaptive weighting module is designed to dynamically recalibrate them. Meanwhile, a novel prior guidance module is introduced in the synthesis network, which effectively aggregates the prior and data features and thus provides better hybrid information to perform the more reasonable image enhancement.