Breast cancer is the most commonly diagnosed cancer and registers the highest number of deaths for women with cancer. Recent advancements in diagnostic activities combined with large-scale screening policies have significantly lowered the mortality rates for breast cancer patients. However, the manual inspection of tissue slides by the pathologists is cumbersome, time-consuming, and is subject to significant inter- and intra-observer variability. Recently, the advent of whole-slide scanning systems have empowered the rapid digitization of pathology slides, and enabled to develop digital workflows. These advances further enable to leverage Artificial Intelligence (AI) to assist, automate, and augment pathological diagnosis. But the AI techniques, especially Deep Learning (DL), require a large amount of high-quality annotated data to learn from. Constructing such task-specific datasets poses several challenges, such as, data-acquisition level constrains, time-consuming and expensive annotations, and anonymization of private information. In this paper, we introduce the BReAst Carcinoma Subtyping (BRACS) dataset, a large cohort of annotated Hematoxylin & Eosin (H&E)-stained images to facilitate the characterization of breast lesions. BRACS contains 547 Whole-Slide Images (WSIs), and 4539 Regions of Interest (ROIs) extracted from the WSIs. Each WSI, and respective ROIs, are annotated by the consensus of three board-certified pathologists into different lesion categories. Specifically, BRACS includes three lesion types, i.e., benign, malignant and atypical, which are further subtyped into seven categories. It is, to the best of our knowledge, the largest annotated dataset for breast cancer subtyping both at WSI- and ROI-level. Further, by including the understudied atypical lesions, BRACS offers an unique opportunity for leveraging AI to better understand their characteristics.

Deep learning researchers have a keen interest in proposing two new novel activation functions which can boost network performance. A good choice of activation function can have significant consequences in improving network performance. A handcrafted activation is the most common choice in neural network models. ReLU is the most common choice in the deep learning community due to its simplicity though ReLU has some serious drawbacks. In this paper, we have proposed a new novel activation function based on approximation of known activation functions like Leaky ReLU, and we call this function Smooth Maximum Unit (SMU). Replacing ReLU by SMU, we have got 6.22% improvement in the CIFAR100 dataset with the ShuffleNet V2 model.

Recent advancements of Deep Neural Networks (DNNs) have seen widespread deployment in multiple security-sensitive domains. The need of resource-intensive training and use of valuable domain-specific training data have made these models a top intellectual property (IP) for model owners. One of the major threats to the DNN privacy is model extraction attacks where adversaries attempt to steal sensitive information in DNN models. Recent studies show hardware-based side channel attacks can reveal internal knowledge about DNN models (e.g., model architectures) However, to date, existing attacks cannot extract detailed model parameters (e.g., weights/biases). In this work, for the first time, we propose an advanced model extraction attack framework DeepSteal that effectively steals DNN weights with the aid of memory side-channel attack. Our proposed DeepSteal comprises two key stages. Firstly, we develop a new weight bit information extraction method, called HammerLeak, through adopting the rowhammer based hardware fault technique as the information leakage vector. HammerLeak leverages several novel system-level techniques tailed for DNN applications to enable fast and efficient weight stealing. Secondly, we propose a novel substitute model training algorithm with Mean Clustering weight penalty, which leverages the partial leaked bit information effectively and generates a substitute prototype of the target victim model. We evaluate this substitute model extraction method on three popular image datasets (e.g., CIFAR-10/100/GTSRB) and four DNN architectures (e.g., ResNet-18/34/Wide-ResNet/VGG-11). The extracted substitute model has successfully achieved more than 90 % test accuracy on deep residual networks for the CIFAR-10 dataset. Moreover, our extracted substitute model could also generate effective adversarial input samples to fool the victim model.

The popularity of social media has created problems such as hate speech and sexism. The identification and classification of sexism in social media are very relevant tasks, as they would allow building a healthier social environment. Nevertheless, these tasks are considerably challenging. This work proposes a system to use multilingual and monolingual BERT and data points translation and ensemble strategies for sexism identification and classification in English and Spanish. It was conducted in the context of the sEXism Identification in Social neTworks shared 2021 (EXIST 2021) task, proposed by the Iberian Languages Evaluation Forum (IberLEF). The proposed system and its main components are described, and an in-depth hyperparameters analysis is conducted. The main results observed were: (i) the system obtained better results than the baseline model (multilingual BERT); (ii) ensemble models obtained better results than monolingual models; and (iii) an ensemble model considering all individual models and the best standardized values obtained the best accuracies and F1-scores for both tasks. This work obtained first place in both tasks at EXIST, with the highest accuracies (0.780 for task 1 and 0.658 for task 2) and F1-scores (F1-binary of 0.780 for task 1 and F1-macro of 0.579 for task 2).

Adversarial attacks on graphs have posed a major threat to the robustness of graph machine learning (GML) models. Naturally, there is an ever-escalating arms race between attackers and defenders. However, the strategies behind both sides are often not fairly compared under the same and realistic conditions. To bridge this gap, we present the Graph Robustness Benchmark (GRB) with the goal of providing a scalable, unified, modular, and reproducible evaluation for the adversarial robustness of GML models. GRB standardizes the process of attacks and defenses by 1) developing scalable and diverse datasets, 2) modularizing the attack and defense implementations, and 3) unifying the evaluation protocol in refined scenarios. By leveraging the GRB pipeline, the end-users can focus on the development of robust GML models with automated data processing and experimental evaluations. To support open and reproducible research on graph adversarial learning, GRB also hosts public leaderboards across different scenarios. As a starting point, we conduct extensive experiments to benchmark baseline techniques. GRB is open-source and welcomes contributions from the community.

Explainable machine learning attracts increasing attention as it improves transparency of models, which is helpful for machine learning to be trusted in real applications. However, explanation methods have recently been demonstrated to be vulnerable to manipulation, where we can easily change a model's explanation while keeping its prediction constant. To tackle this problem, some efforts have been paid to use more stable explanation methods or to change model configurations. In this work, we tackle the problem from the training perspective, and propose a new training scheme called Adversarial Training on EXplanations (ATEX) to improve the internal explanation stability of a model regardless of the specific explanation method being applied. Instead of directly specifying explanation values over data instances, ATEX only puts requirement on model predictions which avoids involving second-order derivatives in optimization. As a further discussion, we also find that explanation stability is closely related to another property of the model, i.e., the risk of being exposed to adversarial attack. Through experiments, besides showing that ATEX improves model robustness against manipulation targeting explanation, it also brings additional benefits including smoothing explanations and improving the efficacy of adversarial training if applied to the model. The codes of our work are available at: https://github.com/DefIntpMan.

Artificial intelligence (AI) technology is increasingly used for digital orthodontics, but one of the challenges is to automatically and accurately detect tooth landmarks and axes. This is partly because of sophisticated geometric definitions of them, and partly due to large variations among individual tooth and across different types of tooth. As such, we propose a deep learning approach with a labeled dataset by professional dentists to the tooth landmark/axis detection on tooth model that are crucial for orthodontic treatments. Our method can extract not only tooth landmarks in the form of point (e.g. cusps), but also axes that measure the tooth angulation and inclination. The proposed network takes as input a 3D tooth model and predicts various types of the tooth landmarks and axes. Specifically, we encode the landmarks and axes as dense fields defined on the surface of the tooth model. This design choice and a set of added components make the proposed network more suitable for extracting sparse landmarks from a given 3D tooth model. Extensive evaluation of the proposed method was conducted on a set of dental models prepared by experienced dentists. Results show that our method can produce tooth landmarks with high accuracy. Our method was examined and justified via comparison with the state-of-the-art methods as well as the ablation studies.

Purpose: To assess whether the three-dimensional (3D) structural configuration of the central retinal vessel trunk and its branches (CRVT&B) could be used as a diagnostic marker for glaucoma. Method: We trained a deep learning network to automatically segment the CRVT&B from the B-scans of the optical coherence tomography (OCT) volume of the optic nerve head (ONH). Subsequently, two different approaches were used for glaucoma diagnosis using the structural configuration of the CRVT&B as extracted from the OCT volumes. In the first approach, we aimed to provide a diagnosis using only 3D CNN and the 3D structure of the CRVT&B. For the second approach, we projected the 3D structure of the CRVT&B orthographically onto three planes to obtain 2D images, and then a 2D CNN was used for diagnosis. The segmentation accuracy was evaluated using the Dice coefficient, whereas the diagnostic accuracy was assessed using the area under the receiver operating characteristic curves (AUC). The diagnostic performance of the CRVT&B was also compared with that of retinal nerve fiber layer (RNFL) thickness. Results: Our segmentation network was able to efficiently segment retinal blood vessels from OCT scans. On a test set, we achieved a Dice coefficient of 0.81\pm0.07. The 3D and 2D diagnostic networks were able to differentiate glaucoma from non-glaucoma subjects with accuracies of 82.7% and 83.3%, respectively. The corresponding AUCs for CRVT&B were 0.89 and 0.90, higher than those obtained with RNFL thickness alone. Conclusions: Our work demonstrated that the diagnostic power of the CRVT&B is superior to that of a gold-standard glaucoma parameter, i.e., RNFL thickness. Our work also suggested that the major retinal blood vessels form a skeleton -- the configuration of which may be representative of major ONH structural changes as typically observed with the development and progression of glaucoma.

An AI chatbot provides an impressive response after learning from the trained dataset. In this decade, most of the research work demonstrates that deep neural models superior to any other model. RNN model regularly used for determining the sequence-related problem like a question and it answers. This approach acquainted with everyone as seq2seq learning. In a seq2seq model mechanism, it has encoder and decoder. The encoder embedded any input sequence, and the decoder embedded output sequence. For reinforcing the seq2seq model performance, attention mechanism added into the encoder and decoder. After that, the transformer model has introduced itself as a high-performance model with multiple attention mechanism for solving the sequence-related dilemma. This model reduces training time compared with RNN based model and also achieved state-of-the-art performance for sequence transduction. In this research, we applied the transformer model for Bengali general knowledge chatbot based on the Bengali general knowledge Question Answer (QA) dataset. It scores 85.0 BLEU on the applied QA data. To check the comparison of the transformer model performance, we trained the seq2seq model with attention on our dataset that scores 23.5 BLEU.

Reconstructing missing information in epidemic spreading on contact networks can be essential in prevention and containment strategies. For instance, identifying and warning infective but asymptomatic individuals (e.g., manual contact tracing) helped contain outbreaks in the COVID-19 pandemic. The number of possible epidemic cascades typically grows exponentially with the number of individuals involved. The challenge posed by inference problems in the epidemics processes originates from the difficulty of identifying the almost negligible subset of those compatible with the evidence (for instance, medical tests). Here we present a new generative neural networks framework that can sample the most probable infection cascades compatible with observations. Moreover, the framework can infer the parameters governing the spreading of infections. The proposed method obtains better or comparable results with existing methods on the patient zero problem, risk assessment, and inference of infectious parameters in synthetic and real case scenarios like spreading infections in workplaces and hospitals.