There has been significant recent progress designing deep generative models that generate realistic sequence data such as text or music. Nevertheless, it remains difficult to incorporate high-level structure to guide the generative process, and many such models perform well on local coherence, but less so on global coherence. We propose a novel approach for incorporating global structure in the form of relational constraints between different subcomponents of an example (e.g., lines of a poem or measures of music). Our generative model has two parts: (i) one model to generate a realistic set of relational constraints, and (ii) a second model to generate realistic data satisfying these constraints. For model (i), we propose a constrained optimization algorithm that infers the relational constraints present in the training data, and then learn a generative model based on the resulting constraint data.

Imagen builds on the power of large transformer language models in understanding text and hinges on the strength of diffusion models in high-fidelity image generation. Our key discovery is that generic large language models (e.g., T5), pretrained on text-only corpora, are surprisingly effective at encoding text for image synthesis: increasing the size of the language model in Imagen boosts both sample fidelity and image-text alignment much more than increasing the size of the image diffusion model. Imagen achieves a new state-of-the-art FID score of 7.27 on the COCO dataset, without ever training on COCO, and human raters find Imagen samples to be on par with the COCO data itself in image-text alignment. To assess text-to-image models in greater depth, we introduce DrawBench, a comprehensive and challenging benchmark for text-to-image models. With DrawBench, we compare Imagen with recent methods including VQ-GAN CLIP, Latent Diffusion Models, and DALL-E 2, and find that human raters prefer Imagen over other models in side-by-side comparisons, both in terms of sample quality and image-text alignment.

Periodic graphs are graphs consisting of repetitive local structures, such as crystal nets and polygon mesh. Their generative modeling has great potential in real-world applications such as material design and graphics synthesis. Classical models either rely on domain-specific predefined generation principles (e.g., in crystal net design), or follow geometry-based prescribed rules. Recently, deep generative models have shown great promise in automatically generating general graphs. However, their advancement into periodic graphs has not been well explored due to several key challenges in 1) maintaining graph periodicity; 2) disentangling local and global patterns; and 3) efficiency in learning repetitive patterns.

Diffusion Models (DMs) are state-of-the-art generative models that learn a reversible corruption process from iterative noise addition and denoising. They are the backbone of many generative AI applications, such as text-to-image conditional generation. However, recent studies have shown that basic unconditional DMs (e.g., DDPM and DDIM) are vulnerable to backdoor injection, a type of output manipulation attack triggered by a maliciously embedded pattern at model input. This paper presents a unified backdoor attack framework (VillanDiffusion) to expand the current scope of backdoor analysis for DMs. Our framework covers mainstream unconditional and conditional DMs (denoising-based and score-based) and various training-free samplers for holistic evaluations.

Our research explores the development and application of musical agents, human-in-the-loop generative AI systems designed to support music performance and improvisation within co-creative spaces. We introduce MACAT and MACataRT, two distinct musical agent systems crafted to enhance interactive music-making between human musicians and AI. MACAT is optimized for agent-led performance, employing real-time synthesis and self-listening to shape its output autonomously, while MACataRT provides a flexible environment for collaborative improvisation through audio mosaicing and sequence-based learning. Both systems emphasize training on personalized, small datasets, fostering ethical and transparent AI engagement that respects artistic integrity. This research highlights how interactive, artist-centred generative AI can expand creative possibilities, empowering musicians to explore new forms of artistic expression in real-time, performance-driven and music improvisation contexts.

Question: What is the performance and reasoning ability of OpenAI o1 compared to other large language models in addressing ophthalmology-specific questions? Findings: This study evaluated OpenAI o1 and five LLMs using 6,990 ophthalmological questions from MedMCQA. O1 achieved the highest accuracy (0.88) and macro-F1 score but ranked third in reasoning capabilities based on text-generation metrics. Across subtopics, o1 ranked first in ``Lens'' and ``Glaucoma'' but second to GPT-4o in ``Corneal and External Diseases'', ``Vitreous and Retina'' and ``Oculoplastic and Orbital Diseases''. Subgroup analyses showed o1 performed better on queries with longer ground truth explanations. Meaning: O1's reasoning enhancements may not fully extend to ophthalmology, underscoring the need for domain-specific refinements to optimize performance in specialized fields like ophthalmology.

Hallucinations remain a significant challenge in current Generative AI models, undermining trust in AI systems and their reliability. This study investigates how orchestrating multiple specialized Artificial Intelligent Agents can help mitigate such hallucinations, with a focus on systems leveraging Natural Language Processing (NLP) to facilitate seamless agent interactions. To achieve this, we design a pipeline that introduces over three hundred prompts, purposefully crafted to induce hallucinations, into a front-end agent. The outputs are then systematically reviewed and refined by second- and third-level agents, each employing distinct large language models and tailored strategies to detect unverified claims, incorporate explicit disclaimers, and clarify speculative content. Additionally, we introduce a set of novel Key Performance Indicators (KPIs) specifically designed to evaluate hallucination score levels. A dedicated fourth-level AI agent is employed to evaluate these KPIs, providing detailed assessments and ensuring accurate quantification of shifts in hallucination-related behaviors. A core component of this investigation is the use of the OVON (Open Voice Network) framework, which relies on universal NLP-based interfaces to transfer contextual information among agents. Through structured JSON messages, each agent communicates its assessment of the hallucination likelihood and the reasons underlying questionable content, thereby enabling the subsequent stage to refine the text without losing context. The results demonstrate that employing multiple specialized agents capable of interoperating with each other through NLP-based agentic frameworks can yield promising outcomes in hallucination mitigation, ultimately bolstering trust within the AI community.

The rapid development of artificial intelligence has brought about substantial advancements in the field. One promising direction is the integration of Large Language Models (LLMs) with structured knowledge-based systems. This approach aims to enhance AI capabilities by combining the generative language understanding of LLMs with the precise knowledge representation of structured systems. This survey explores the synergy between LLMs and knowledge bases, focusing on real-world applications and addressing associated technical, operational, and ethical challenges. Through a comprehensive literature review, the study identifies critical issues and evaluates existing solutions. The paper highlights the benefits of integrating generative AI with knowledge bases, including improved data contextualization, enhanced model accuracy, and better utilization of knowledge resources. The findings provide a detailed overview of the current state of research, identify key gaps, and offer actionable recommendations. These insights contribute to advancing AI technologies and support their practical deployment across various sectors.

Revitalizing Japan's remote areas has become a crucial task, and Matsue City exemplifies this effort in its temporary event spaces, created through collective efforts to foster urban vibrancy and bring together residents and visitors. This research examines the relationship between data-driven in-sights using generative AI and visual attractiveness by evaluating tempo-rary events in Matsue City, particularly considering the cognitive-cultural differences in processing visual information of the participants. The first phase employs semantic keyword extraction from interviews, categorizing responses into physical elements, activities, and atmosphere. The second phase analyzes spatial perception through three categories: layout hierar-chy, product visibility, and visual attention. The correlation indicates that successful event design requires a balance between spatial efficiency and diverse needs, with a spatial organization that optimizes visitor flow and visibility strategies considering cultural and demographic diversity. These findings contribute to understanding the urban quality of temporary event spaces and offer a replicable framework for enhancing the visual appeal of events in remote areas throughout Japan.

Developing deep generative models has been an emerging field due to the ability to model and generate complex data for various purposes, such as image synthesis and molecular design. However, the advance of deep generative models is limited by the challenges to generate objects that possess multiple desired properties because: 1) the existence of complex correlation among real-world properties is common but hard to identify; 2) controlling individual property enforces an implicit partially control of its correlated properties, which is difficult to model; 3) controlling multiple properties under variour manners simultaneously is hard and underexplored. We address these challenges by proposing a novel deep generative framework that recovers semantics and correlation of properties through disentangled latent vectors. The correlation is handled via an explainable mask pooling layer, and properties are precisely retained by the generated objects via the mutual dependence between latent vectors and properties. Our generative model preserves properties of interest while handles correlation and conflicts of properties under a multi-objective optimization framework. The experiments demonstrate our model's superior performance in generating objects with desired properties.