Generative AI
Advancing AI-Powered Medical Image Synthesis: Insights from MedVQA-GI Challenge Using CLIP, Fine-Tuned Stable Diffusion, and Dream-Booth + LoRA
Peter, Ojonugwa Oluwafemi Ejiga, Rahman, Md Mahmudur, Khalifa, Fahmi
The MEDVQA-GI challenge addresses the integration of AI-driven text-to-image generative models in medical diagnostics, aiming to enhance diagnostic capabilities through synthetic image generation. Existing methods primarily focus on static image analysis and lack the dynamic generation of medical imagery from textual descriptions. This study intends to partially close this gap by introducing a novel approach based on fine-tuned generative models to generate dynamic, scalable, and precise images from textual descriptions. Particularly, our system integrates fine-tuned Stable Diffusion and DreamBooth models, as well as Low-Rank Adaptation (LORA), to generate high-fidelity medical images. The problem is around two sub-tasks namely: image synthesis (IS) and optimal prompt production (OPG). The former creates medical images via verbal prompts, whereas the latter provides prompts that produce high-quality images in specified categories. The study emphasizes the limitations of traditional medical image generation methods, such as hand sketching, constrained datasets, static procedures, and generic models. Our evaluation measures showed that Stable Diffusion surpasses CLIP and DreamBooth + LORA in terms of producing high-quality, diversified images. Specifically, Stable Diffusion had the lowest Fr\'echet Inception Distance (FID) scores (0.099 for single center, 0.064 for multi-center, and 0.067 for combined), indicating higher image quality. Furthermore, it had the highest average Inception Score (2.327 across all datasets), indicating exceptional diversity and quality. This advances the field of AI-powered medical diagnosis. Future research will concentrate on model refining, dataset augmentation, and ethical considerations for efficiently implementing these advances into clinical practice
Supervised Fine-Tuning LLMs to Behave as Pedagogical Agents in Programming Education
Ross, Emily, Kansal, Yuval, Renzella, Jake, Vassar, Alexandra, Taylor, Andrew
Large language models (LLMs) are increasingly being explored in higher education, yet their effectiveness as teaching agents remains underexamined. In this paper, we present the development of GuideLM, a fine-tuned LLM designed for programming education. GuideLM has been integrated into the Debugging C Compiler (DCC), an educational C compiler that leverages LLMs to generate pedagogically sound error explanations. Previously, DCC relied on off-the-shelf OpenAI models, which, while accurate, often over-assisted students by directly providing solutions despite contrary prompting. To address this, we employed supervised fine-tuning (SFT) on a dataset of 528 student-question/teacher-answer pairs, creating two models: GuideLM and GuideLM-mini, fine-tuned on ChatGPT-4o and 4o-mini, respectively. We conducted an expert analysis of 400 responses per model, comparing their pedagogical effectiveness against base OpenAI models. Our evaluation, grounded in constructivism and cognitive load theory, assessed factors such as conceptual scaffolding, clarity, and Socratic guidance. Results indicate that GuideLM and GuideLM-mini improve pedagogical performance, with an 8% increase in Socratic guidance and a 58% improvement in economy of words compared to GPT-4o. However, this refinement comes at the cost of a slight reduction in general accuracy. While further work is needed, our findings suggest that fine-tuning LLMs with targeted datasets is a promising approach for developing models better suited to educational contexts.
Bridging Legal Knowledge and AI: Retrieval-Augmented Generation with Vector Stores, Knowledge Graphs, and Hierarchical Non-negative Matrix Factorization
Barron, Ryan C., Eren, Maksim E., Serafimova, Olga M., Matuszek, Cynthia, Alexandrov, Boian S.
Agentic Generative AI, powered by Large Language Models (LLMs) with Retrieval-Augmented Generation (RAG), Knowledge Graphs (KGs), and Vector Stores (VSs), represents a transformative technology applicable to specialized domains such as legal systems, research, recommender systems, cybersecurity, and global security, including proliferation research. This technology excels at inferring relationships within vast unstructured or semi-structured datasets. The legal domain here comprises complex data characterized by extensive, interrelated, and semi-structured knowledge systems with complex relations. It comprises constitutions, statutes, regulations, and case law. Extracting insights and navigating the intricate networks of legal documents and their relations is crucial for effective legal research. Here, we introduce a generative AI system that integrates RAG, VS, and KG, constructed via Non-Negative Matrix Factorization (NMF), to enhance legal information retrieval and AI reasoning and minimize hallucinations. In the legal system, these technologies empower AI agents to identify and analyze complex connections among cases, statutes, and legal precedents, uncovering hidden relationships and predicting legal trends-challenging tasks that are essential for ensuring justice and improving operational efficiency. Our system employs web scraping techniques to systematically collect legal texts, such as statutes, constitutional provisions, and case law, from publicly accessible platforms like Justia. It bridges the gap between traditional keyword-based searches and contextual understanding by leveraging advanced semantic representations, hierarchical relationships, and latent topic discovery. This framework supports legal document clustering, summarization, and cross-referencing, for scalable, interpretable, and accurate retrieval for semi-structured data while advancing computational law and AI.
Deterministic or probabilistic? The psychology of LLMs as random number generators
Large Language Models (LLMs) have transformed text generation through inherently probabilistic context-aware mechanisms, mimicking human natural language. In this paper, we systematically investigate the performance of various LLMs when generating random numbers, considering diverse configurations such as different model architectures, numerical ranges, temperature, and prompt languages. Our results reveal that, despite their stochastic transformers-based architecture, these models often exhibit deterministic responses when prompted for random numerical outputs. In particular, we find significant differences when changing the model, as well as the prompt language, attributing this phenomenon to biases deeply embedded within the training data. Models such as DeepSeek-R1 can shed some light on the internal reasoning process of LLMs, despite arriving to similar results. These biases induce predictable patterns that undermine genuine randomness, as LLMs are nothing but reproducing our own human cognitive biases.
How Sam Altman Could Break Up Elon Musk and Donald Trump
The rivalry between Sam Altman and Elon Musk is entering its Apprentice era. Both men have the ambition to redefine how the modern world works--and both are jockeying for President Donald Trump's blessing to accelerate their plans. Altman's company, OpenAI, as well as Musk's ventures--which include SpaceX, Tesla, and xAI--all depend to some degree on federal dollars, permits, and regulatory support. The president could influence whether OpenAI or xAI produces the next major AI breakthrough, whether Musk can succeed in sending a human to Mars, and whether Altman's big bet on nuclear energy, and fusion reactors in particular, pans out. Understanding the competition between these two men helps illuminate Trump's particular style of governing--one defined by patronage and dealmaking.
Everything announced at Amazon's Alexa AI event
Amazon held its first major product event of the year on Wednesday and, as expected, it was largely about Alexa. The company first announced its next-gen, AI-powered voice assistant back in 2023, but technical issues forced Amazon to delay its formal unveiling and rollout. An Alexa upgrade means that Amazon has a swathe of new devices ready to support the latest version of the voice assistant. Amazon's hardware chief, Panos Panay, and his devices and services team were at the event to show off Alexa . Here's a rundown of everything Amazon announced at its first devices event of 2025: After lots (and lots) of boring rambling about generative AI from Amazon CEO Andy Jassy at Wednesday's event, Panay took the mic to start sharing the actual news. Alexa is the name of the company's upgraded voice assistant.
Alibaba offers free access to its AI model that can generate realistic video and images
Alibaba is giving people free access to its generative artificial intelligence models that can produce highly realistic videos and images from both text and image input. The company has announced that four variants of its Wan 2.1 series, the latest version of its generative AI technology, are now open source and can be downloaded and modified by users. Researchers, academics and commercial entities can all get them from Alibaba Cloud's ModelScope and Hugging Face platforms, both of which give people access to open-source AI models. As Reuters said, the models Alibaba has open sourced are called T2V-1.3B, T2V-14B, I2V-14B-720P and I2V-14B-480P, with the 14B indicating that the model can accept 14 billion parameters.
UK universities warned to 'stress-test' assessments as 92% of students use AI
British universities have been warned to "stress-test" all assessments after new research revealed "almost all" undergraduates are using generative artificial intelligence (genAI) in their studies. A survey of 1,000 students โ both domestic and international โ found there had been an "explosive increase" in the use of genAI in the past 12 months. Almost nine out of 10 (88%) in the 2025 poll said they used tools such as ChatGPT for their assessments, up from 53% last year. The proportion using any AI tool surged from 66% in 2024 to 92% in 2025, meaning just 8% of students are not using AI, according to a report published by the Higher Education Policy Institute and Kortext, a digital etextbook provider. Josh Freeman, the report's author, said such dramatic changes in behaviour in just 12 months were almost unheard of, and warned: "Universities should take heed: generative AI is here to stay. "There are urgent lessons here for institutions," Freeman said. "Every assessment must be reviewed in case it can be completed easily using AI.
Talking like Piping and Instrumentation Diagrams (P&IDs)
Alimin, Achmad Anggawirya, Goldstein, Dominik P., Balhorn, Lukas Schulze, Schweidtmann, Artur M.
We propose a methodology that allows communication with Piping and Instrumentation Diagrams (P&IDs) using natural language. In particular, we represent P&IDs through the DEXPI data model as labeled property graphs and integrate them with Large Language Models (LLMs). The approach consists of three main parts: 1) P&IDs are cast into a graph representation from the DEXPI format using our pyDEXPI Python package. 2) A tool for generating P&ID knowledge graphs from pyDEXPI. 3) Integration of the P&ID knowledge graph to LLMs using graph-based retrieval augmented generation (graph-RAG). This approach allows users to communicate with P&IDs using natural language. It extends LLM's ability to retrieve contextual data from P&IDs and mitigate hallucinations. Leveraging the LLM's large corpus, the model is also able to interpret process information in PIDs, which could help engineers in their daily tasks. In the future, this work will also open up opportunities in the context of other generative Artificial Intelligence (genAI) solutions on P&IDs, and AI-assisted HAZOP studies.
BEYONDWORDS is All You Need: Agentic Generative AI based Social Media Themes Extractor
Ghali, Mohammed-Khalil, Farrag, Abdelrahman, Lam, Sarah, Won, Daehan
Thematic analysis of social media posts provides a major understanding of public discourse, yet traditional methods often struggle to capture the complexity and nuance of unstructured, large-scale text data. This study introduces a novel methodology for thematic analysis that integrates tweet embeddings from pre-trained language models, dimensionality reduction using and matrix factorization, and generative AI to identify and refine latent themes. Our approach clusters compressed tweet representations and employs generative AI to extract and articulate themes through an agentic Chain of Thought (CoT) prompting, with a secondary LLM for quality assurance. This methodology is applied to tweets from the autistic community, a group that increasingly uses social media to discuss their experiences and challenges. By automating the thematic extraction process, the aim is to uncover key insights while maintaining the richness of the original discourse. This autism case study demonstrates the utility of the proposed approach in improving thematic analysis of social media data, offering a scalable and adaptable framework that can be applied to diverse contexts. The results highlight the potential of combining machine learning and Generative AI to enhance the depth and accuracy of theme identification in online communities.