Conversational assistants are becoming more and more popular, including in healthcare, partly because of the availability and capabilities of Large Language Models. There is a need for controlled, probing evaluations with real stakeholders which can highlight advantages and disadvantages of more traditional architectures and those based on generative AI. We present a within-group user study to compare two versions of a conversational assistant that allows heart failure patients to ask about salt content in food. One version of the system was developed in-house with a neurosymbolic architecture, and one is based on ChatGPT. The evaluation shows that the in-house system is more accurate, completes more tasks and is less verbose than the one based on ChatGPT; on the other hand, the one based on ChatGPT makes fewer speech errors and requires fewer clarifications to complete the task. Patients show no preference for one over the other.

As large language models (LLMs) scale in size and adoption, their computational and environmental costs continue to rise. Prior benchmarking efforts have primarily focused on latency reduction in idealized settings, often overlooking the diverse real-world inference workloads that shape energy use. In this work, we systematically analyze the energy implications of common inference efficiency optimizations across diverse Natural Language Processing (NLP) and generative Artificial Intelligence (AI) workloads, including conversational AI and code generation. We introduce a modeling approach that approximates real-world LLM workflows through a binning strategy for input-output token distributions and batch size variations. Our empirical analysis spans software frameworks, decoding strategies, GPU architectures, online and offline serving settings, and model parallelism configurations. We show that the effectiveness of inference optimizations is highly sensitive to workload geometry, software stack, and hardware accelerators, demonstrating that naive energy estimates based on FLOPs or theoretical GPU utilization significantly underestimate real-world energy consumption. Our findings reveal that the proper application of relevant inference efficiency optimizations can reduce total energy use by up to 73% from unoptimized baselines. These insights provide a foundation for sustainable LLM deployment and inform energy-efficient design strategies for future AI infrastructure.

Large language models (LLMs) often generate responses that deviate from user input or training data, a phenomenon known as "hallucination." These hallucinations undermine user trust and hinder the adoption of generative AI systems. Addressing hallucinations is essential for the advancement of LLMs. This paper introduces a comprehensive hallucination benchmark, incorporating both new extrinsic and existing intrinsic evaluation tasks, built upon clear taxonomy of hallucination. A major challenge in benchmarking hallucinations is the lack of a unified framework due to inconsistent definitions and categorizations. We disentangle LLM hallucination from "factuality," proposing a clear taxonomy that distinguishes between extrinsic and intrinsic hallucinations, to promote consistency and facilitate research. Extrinsic hallucinations, where the generated content is not consistent with the training data, are increasingly important as LLMs evolve. Our benchmark includes dynamic test set generation to mitigate data leakage and ensure robustness against such leakage. We also analyze existing benchmarks, highlighting their limitations and saturation. The work aims to: (1) establish a clear taxonomy of hallucinations, (2) introduce new extrinsic hallucination tasks, with data that can be dynamically regenerated to prevent saturation by leakage, (3) provide a comprehensive analysis of existing benchmarks, distinguishing them from factuality evaluations.

As generative AI models become increasingly integrated into high-stakes domains, the need for robust methods to evaluate their ethical reasoning becomes increasingly important. This paper introduces a five-dimensional audit model -- assessing Analytic Quality, Breadth of Ethical Considerations, Depth of Explanation, Consistency, and Decisiveness -- to evaluate the ethical logic of leading large language models (LLMs). Drawing on traditions from applied ethics and higher-order thinking, we present a multi-battery prompt approach, including novel ethical dilemmas, to probe the models' reasoning across diverse contexts. We benchmark seven major LLMs finding that while models generally converge on ethical decisions, they vary in explanatory rigor and moral prioritization. Chain-of-Thought prompting and reasoning-optimized models significantly enhance performance on our audit metrics. This study introduces a scalable methodology for ethical benchmarking of AI systems and highlights the potential for AI to complement human moral reasoning in complex decision-making contexts.

We propose a symbolic generative task description language and a corresponding inference engine capable of representing arbitrary multimodal tasks as structured symbolic flows. Unlike conventional generative models that rely on large-scale training and implicit neural representations to learn cross-modal mappings, often at high computational cost and with limited flexibility, our framework introduces an explicit symbolic representation comprising three core primitives: functions, parameters, and topological logic. Leveraging a pre-trained language model, our inference engine maps natural language instructions directly to symbolic workflows in a training-free manner. Our framework successfully performs over 12 diverse multimodal generative tasks, demonstrating strong performance and flexibility without the need for task-specific tuning. Experiments show that our method not only matches or outperforms existing state-of-the-art unified models in content quality, but also offers greater efficiency, editability, and interruptibility. We believe that symbolic task representations provide a cost-effective and extensible foundation for advancing the capabilities of generative AI.

In the latest development in an ongoing struggle over OpenAI's future direction--and potentially the future of artificial intelligence itself--dozens of prominent figures are urging the Attorneys General of California and Delaware to block OpenAI's controversial plan to convert from its unique nonprofit-controlled structure to a for-profit company. In a letter made public April 23, signatories including "AI Godfather" Geoffrey Hinton, Harvard legal professor Lawrence Lessig, and several former OpenAI researchers argue the move represents a fundamental betrayal of OpenAI's founding mission. "The proposed restructuring would eliminate essential safeguards, effectively handing control of, and profits from, what could be the most powerful technology ever created to a for-profit entity with legal duties to prioritize shareholder returns," the letter's authors write. It lands as OpenAI faces immense pressure from the other side: failing to implement the restructure by the end of the year could cost the company 20 billion and hamstring future fundraising. OpenAI was founded in 2015 as a non-profit, with its stated mission being to ensure that artificial general intelligence (AGI) "benefits all of humanity" rather than advancing "the private gain of any person."

At the same time, hosted services like generative AI and tailored industry solutions can help companies quickly launch applications and grow the business. To get the most out of these services, companies are turning to cloud optimization--the process of selecting and allocating cloud resources to reduce costs while maximizing performance. But despite all the interest in the cloud, many workloads remain stranded on-premises, and many more are not optimized for efficiency and growth, greatly limiting the forward momentum. Companies are missing out on a virtuous cycle of mutually reinforcing results that comes from even more efficient use of the cloud. Organizations can enhance security, make critical workloads more resilient, protect the customer experience, boost revenues, and generate cost savings.

Streetscape Analysis with Generative AI (SAGAI): Vision-Language Assessment and Mapping of Urban Scenes Joan Perez 1 and Giovanni Fusco 2 1 Urban Geo Analytics, France 2 Universit e Cˆ ote-Azur-CNRS-AMU-Avignon Universit e, ESPACE, France April 2025 Abstract Streetscapes are an essential component of urban space. Their assessment is presently either limited to morphometric properties of their mass skeleton or requires labor-intensive qualitative evaluations of visually perceived qualities. This paper introduces SAGAI: Streetscape Analysis with Generative Artificial Intelligence, a modular workflow for scoring street-level urban scenes using open-access data and vision-language models. SAGAI integrates OpenStreetMap geometries, Google Street View imagery, and a lightweight version of the LLaVA model to generate structured spatial indicators from images via customizable natural language prompts. The pipeline includes an automated mapping module that aggregates visual scores at both the point and street levels, enabling direct cartographic interpretation. It operates without task-specific training or proprietary software dependencies, supporting scalable and interpretable analysis of urban environments. Two exploratory case studies in Nice and Vienna illustrate SAGAI's capacity to produce geospatial outputs from vision-language inference. The initial results show strong performance for binary urban-rural scene classification, moderate precision in commercial feature detection, and lower estimates, but still informative, of sidewalk width. Fully deployable by any user, SAGAI can be easily adapted to a wide range of urban research themes, such as walkability, safety, or urban design, through prompt modification alone. Keywords: Vision-Language Models, Street View Imagery, Streetscape Analysis, Geospatial AI, zero-shot inference 1 Introduction Assessing the qualities and functions of urban streetscapes is essential to understand walkability, safety, commercial vitality, and social life in cities [1, 2, 3]. However, traditional methods for observing and evaluating street-level conditions, such as field surveys, audits, and manual photo interpretation, remain time-consuming, labor-intensive, and difficult to scale beyond small pilot zones [2]. Geo-processing of vector models of the built environment allows the assessment of Email: jperez@urbangeoanalytics.com, ORCID: 0000-0003-3003-0895 Email: giovanni.fusco@univ-cotedazur.fr,

The de novo design of proteins refers to creating proteins with specific structures and functions that do not naturally exist. In recent years, the accumulation of high-quality protein structure and sequence data and technological advancements have paved the way for the successful application of generative artificial intelligence (AI) models in protein design. These models have surpassed traditional approaches that rely on fragments and bioinformatics. They have significantly enhanced the success rate of de novo protein design, and reduced experimental costs, leading to breakthroughs in the field. Among various generative AI models, diffusion models have yielded the most promising results in protein design. In the past two to three years, more than ten protein design models based on diffusion models have emerged. Among them, the representative model, RFDiffusion, has demonstrated success rates in 25 protein design tasks that far exceed those of traditional methods, and other AI-based approaches like RFjoint and hallucination. This review will systematically examine the application of diffusion models in generating protein backbones and sequences. We will explore the strengths and limitations of different models, summarize successful cases of protein design using diffusion models, and discuss future development directions.

Design thrives on feedback. However, gathering constant feedback throughout the design process can be labor-intensive and disruptive. We explore how AI can bridge this gap by providing effortless, ambient feedback. We introduce FeedQUAC, a design companion that delivers real-time AI-generated commentary from a variety of perspectives through different personas. A design probe study with eight participants highlights how designers can leverage quick yet ambient AI feedback to enhance their creative workflows. Participants highlight benefits such as convenience, playfulness, confidence boost, and inspiration from this lightweight feedback agent, while suggesting additional features, like chat interaction and context curation. We discuss the role of AI feedback, its strengths and limitations, and how to integrate it into existing design workflows while balancing user involvement. Our findings also suggest that ambient interaction is a valuable consideration for both the design and evaluation of future creativity support systems.