We explore the potential for combining generative AI with grammar-based visualizations for biomedical data discovery. In our prototype, we use a multi-agent system to generate visualization specifications and apply filters. These visualizations are linked together, resulting in an interactive dashboard that is progressively constructed. Our system leverages the strengths of natural language while maintaining the utility of traditional user interfaces. Furthermore, we utilize generated interactive widgets enabling user adjustment. Finally, we demonstrate the potential utility of this system for biomedical data discovery with a case study.

We present EPIC, an AI-driven platform designed to augment operational data analytics. EPIC employs a hierarchical multi-agent architecture where a top-level large language model provides query processing, reasoning and synthesis capabilities. These capabilities orchestrate three specialized low-level agents for information retrieval, descriptive analytics, and predictive analytics. This architecture enables EPIC to perform HPC operational analytics on multi-modal data, including text, images, and tabular formats, dynamically and iteratively. EPIC addresses the limitations of existing HPC operational analytics approaches, which rely on static methods that struggle to adapt to evolving analytics tasks and stakeholder demands. Through extensive evaluations on the Frontier HPC system, we demonstrate that EPIC effectively handles complex queries. Using descriptive analytics as a use case, fine-tuned smaller models outperform large state-of-the-art foundation models, achieving up to 26% higher accuracy. Additionally, we achieved 19x savings in LLM operational costs compared to proprietary solutions by employing a hybrid approach that combines large foundational models with fine-tuned local open-weight models.

Concerns about text-to-image (T2I) generative models infringing on privacy, copyright, and safety have led to the development of concept erasure techniques (CETs). The goal of an effective CET is to prohibit the generation of undesired "target" concepts specified by the user, while preserving the ability to synthesize high-quality images of other concepts. In this work, we demonstrate that concept erasure has side effects and CETs can be easily circumvented. For a comprehensive measurement of the robustness of CETs, we present the Side Effect Evaluation (SEE) benchmark that consists of hierarchical and compositional prompts describing objects and their attributes. The dataset and an automated evaluation pipeline quantify side effects of CETs across three aspects: impact on neighboring concepts, evasion of targets, and attribute leakage. Our experiments reveal that CETs can be circumvented by using superclass-subclass hierarchy, semantically similar prompts, and compositional variants of the target. We show that CETs suffer from attribute leakage and a counterintuitive phenomenon of attention concentration or dispersal. We release our benchmark and evaluation tools to aid future work on robust concept erasure.

AI systems are rapidly advancing in capability, and frontier model developers broadly acknowledge the need for safeguards against serious misuse. However, this paper demonstrates that fine-tuning, whether via open weights or closed fine-tuning APIs, can produce helpful-only models with safeguards destroyed. In contrast to prior work which is blocked by modern moderation systems or achieved only partial removal of safeguards or degraded output quality, our jailbreak-tuning method teaches models to generate detailed, high-quality responses to arbitrary harmful requests. For example, OpenAI, Google, and Anthropic models will fully comply with requests for CBRN assistance, executing cyberattacks, and other criminal activity. We further show that backdoors can increase not only the stealth but also the severity of attacks. Stronger jailbreak prompts become even more effective in fine-tuning attacks, linking attacks and potentially defenses in the input and weight spaces. Not only are current models vulnerable, more recent ones also appear to be becoming even more vulnerable to these attacks, underscoring the urgent need for tamper-resistant safeguards. Until such safeguards are discovered, companies and policymakers should view the release of any fine-tunable model as simultaneously releasing its evil twin: equally capable as the original model, and usable for any malicious purpose within its capabilities.

Social narratives are known to help autistic children understand and navigate social situations through stories. To ensure effectiveness, however, the materials need to be customized to reflect each child's unique behavioral context, requiring considerable time and effort for parents to practice at home. We present AutiHero, a generative AI-based social narrative system for behavioral guidance, which supports parents to create personalized stories for their autistic children and read them together. AutiHero generates text and visual illustrations that reflect their children's interests, target behaviors, and everyday contexts. In a two-week deployment study with 16 autistic child-parent dyads, parents created 218 stories and read an average of 4.25 stories per day, demonstrating a high level of engagement. AutiHero also provided an effective, low-demanding means to guide children's social behaviors, encouraging positive change. We discuss the implications of generative AI-infused tools to empower parents in guiding their children's behaviors, fostering their social learning.

Unlike in language or vision, one of the fundamental challenges in robot learning is the lack of access to vast data resources. We can further break down the problem into (1) data sparsity from the angle of data representation and (2) data scarcity from the angle of data quantity. In this thesis, I will discuss selected works on two domains: (1) tactile sensing and (2) rehabilitation robots, which are exemplars of data sparsity and scarcity, respectively. Tactile sensing is an essential modality for robotics, but tactile data are often sparse, and for each interaction with the physical world, tactile sensors can only obtain information about the local area of contact. I will discuss my work on learning vision-free tactile-only exploration and manipulation policies through model-free reinforcement learning to make efficient use of sparse tactile information. On the other hand, rehabilitation robots are an example of data scarcity to the extreme due to the significant challenge of collecting biosignals from disabled-bodied subjects at scale for training. I will discuss my work in collaboration with the medical school and clinicians on intent inferral for stroke survivors, where a hand orthosis developed in our lab collects a set of biosignals from the patient and uses them to infer the activity that the patient intends to perform, so the orthosis can provide the right type of physical assistance at the right moment. My work develops machine learning algorithms that enable intent inferral with minimal data, including semi-supervised, meta-learning, and generative AI methods.

The exponential development of generative artificial intelligence (GenAI) technologies like ChatGPT has raised increasing curiosity about their use in higher education, specifically with respect to how students view them, make use of them, and the implications for learning outcomes. This paper employs a hybrid methodological approach involving a systematic literature review and simulation-based modeling to explore student perceptions of GenAI use in the context of higher education. A total of nineteen empirical articles from 2023 through 2025 were selected from the PRISMA-based search targeting the Scopus database. Synthesis of emerging patterns from the literature was achieved by thematic categorization. Six of these had enough quantitative information, i.e., item-level means and standard deviations, to permit probabilistic modeling. One dataset, from the resulting subset, was itself selected as a representative case with which to illustrate inverse-variance weighting by Monte Carlo simulation, by virtue of its well-designed Likert scale format and thematic alignment with the use of computing systems by the researcher. The simulation provided a composite "Success Score" forecasting the strength of the relationship between student perceptions and learning achievements. Findings reveal that attitude factors concerned with usability and real-world usefulness are significantly better predictors of positive learning achievement than affective or trust-based factors. Such an interdisciplinary perspective provides a unique means of linking thematic results with predictive modelling, resonating with longstanding controversies about the proper use of GenAI tools within the university.

Generative AI, especially through large language models (LLMs), is transforming how technical knowledge can be accessed, reused, and extended. PETSc, a widely used numerical library for high-performance scientific computing, has accumulated a rich but fragmented knowledge base over its three decades of development, spanning source code, documentation, mailing lists, GitLab issues, Discord conversations, technical papers, and more. Much of this knowledge remains informal and inaccessible to users and new developers. To activate and utilize this knowledge base more effectively, the PETSc team has begun building an LLM-powered system that combines PETSc content with custom LLM tools -- including retrieval-augmented generation (RAG), reranking algorithms, and chatbots -- to assist users, support developers, and propose updates to formal documentation. This paper presents initial experiences designing and evaluating these tools, focusing on system architecture, using RAG and reranking for PETSc-specific information, evaluation methodologies for various LLMs and embedding models, and user interface design. Leveraging the Argonne Leadership Computing Facility resources, we analyze how LLM responses can enhance the development and use of numerical software, with an initial focus on scalable Krylov solvers. Our goal is to establish an extensible framework for knowledge-centered AI in scientific software, enabling scalable support, enriched documentation, and enhanced workflows for research and development. We conclude by outlining directions for expanding this system into a robust, evolving platform that advances software ecosystems to accelerate scientific discovery.

There is an increasing imperative to integrate programming platforms within AI frameworks to enhance educational tasks for both teachers and students. However, commonly used platforms such as Code.org, Scratch, and Snap fall short of providing the desired AI features and lack adaptability for interdisciplinary applications. This study explores how educational platforms can be improved by incorporating AI and analytics features to create more effective learning environments across various subjects and domains. We interviewed 8 K-12 teachers and asked their practices and needs while using any block-based programming (BBP) platform in their classes. We asked for their approaches in assessment, course development and expansion of resources, and student monitoring in their classes. Thematic analysis of the interview transcripts revealed both commonalities and differences in the AI tools needed between the STEM and non-STEM groups. Our results indicated advanced AI features that could promote BBP platforms. Both groups stressed the need for integrity and plagiarism checks, AI adaptability, customized rubrics, and detailed feedback in assessments. Non-STEM teachers also emphasized the importance of creative assignments and qualitative assessments. Regarding resource development, both AI tools desired for updating curricula, tutoring libraries, and generative AI features. Non-STEM teachers were particularly interested in supporting creative endeavors, such as art simulations. For student monitoring, both groups prioritized desktop control, daily tracking, behavior monitoring, and distraction prevention tools. Our findings identify specific AI-enhanced features needed by K-12 teachers across various disciplines and lay the foundation for creating more efficient, personalized, and engaging educational experiences.

Nvidia's $100 billion investment is meant to help OpenAI build data centers with a capacity of at least 10 gigawatts of power -- equipped with Nvidia's advanced chips to train and deploy AI models. Nvidia will invest as much as $100 billion in OpenAI to support new data centers and other artificial intelligence infrastructure, a blockbuster deal that underscores booming demand for AI tools like ChatGPT and the computing power needed to make them run. The companies announced the agreement Monday, saying they'd signed a letter of intent for a strategic deal. The investment is meant to help OpenAI build data centers with a capacity of at least 10 gigawatts of power -- equipped with Nvidia's advanced chips to train and deploy AI models. The money will be provided in stages, with the first $10 billion coming when the deal is signed, according to people familiar with the matter. Nvidia is making the investment in cash and will receive OpenAI equity as part of the deal, said the people, who asked not to be identified because the talks were private.