In time-critical settings such as assistive driving, assistants often rely on alerts or haptic signals to prompt rapid human attention, but these cues usually leave humans to interpret situations and decide responses independently, introducing potential delays or ambiguity in meaning. Language-based assistive systems can instead provide instructions backed by context, offering more informative guidance. However, current approaches (e.g., social assistive robots) largely prioritize content generation while overlooking critical timing factors such as verbal conveyance duration, human comprehension delays, and subsequent follow-through duration. These timing considerations are crucial in time-critical settings, where even minor delays can substantially affect outcomes. We aim to study this inherent trade-off between timeliness and informativeness by framing the challenge as a sequential decision-making problem using an augmented-state Markov Decision Process. We design a framework combining reinforcement learning and a generated offline taxonomy dataset, where we balance the trade-off while enabling a scalable taxonomy dataset generation pipeline. Empirical evaluation with synthetic humans shows our framework improves success rates by over 40% compared to methods that ignore time delays, while effectively balancing timeliness and informativeness. It also exposes an often-overlooked trade-off between these two factors, opening new directions for optimizing communication in time-critical human-AI assistance.

We test a new method, which we will abbreviate using the acronym BVM (Basis Vectors Method), in its ability to judge the state changes in images through using language embeddings. We used the MIT-States dataset, containing about 53,000 images, to gather all of our data, which has 225 nouns and 115 adjectives, with each noun having about 9 different adjectives, forming approximately 1000 noun-adjective pairs. For our first experiment, we test our method's ability to determine the state of each noun class separately against other metrics for comparison. These metrics are cosine similarity, dot product, product quantization, binary index, Naive Bayes, and a custom neural network. Among these metrics, we found that our proposed BVM performs the best in classifying the states for each noun. We then perform a second experiment where we try using BVM to determine if it can differentiate adjectives from one another for each adjective separately. We compared the abilities of BVM to differentiate adjectives against the proposed method the MIT-States paper suggests: using a logistic regression model. In the end, we did not find conclusive evidence that our BVM metric could perform better than the logistic regression model at discerning adjectives. Yet, we were able to find evidence for possible improvements to our method; this leads to the chance of increasing our method's accuracy through certain changes in our methodologies.

Graphical user interface (GUI) agents have advanced rapidly but still struggle with complex tasks involving novel UI elements, long-horizon actions, and personalized trajectories. In this work, we introduce Instruction Agent, a GUI agent that leverages expert demonstrations to solve such tasks, enabling completion of otherwise difficult workflows. Given a single demonstration, the agent extracts step-by-step instructions and executes them by strictly following the trajectory intended by the user, which avoids making mistakes during execution. The agent leverages the verifier and backtracker modules further to improve robustness. Both modules are critical to understand the current outcome from each action and handle unexpected interruptions(such as pop-up windows) during execution. Our experiments show that Instruction Agent achieves a 60% success rate on a set of tasks in OSWorld that all top-ranked agents failed to complete. The Instruction Agent offers a practical and extensible framework, bridging the gap between current GUI agents and reliable real-world GUI task automation.

The Trapped Gyro-Landau Fluid (TGLF) model provides fast, accurate predictions of turbulent transport in tokamaks, but whole device simulations requiring thousands of evaluations remain computationally expensive. Neural network (NN) surrogates offer accelerated inference with fully differentiable approximations that enable gradient-based coupling but typically require large training datasets to capture transport flux variations across plasma conditions, creating significant training burden and limiting applicability to expensive gyrokinetic simulations. We propose \textbf{TGLF-SINN (Spectra-Informed Neural Network)} with three key innovations: (1) principled feature engineering that reduces target prediction range, simplifying the learning task; (2) physics-guided regularization of transport spectra to improve generalization under sparse data; and (3) Bayesian Active Learning (BAL) to strategically select training samples based on model uncertainty, reducing data requirements while maintaining accuracy. Our approach achieves superior performance with significantly less training data. In offline settings, TGLF-SINN reduces logarithmic root mean squared error (LRMSE) by 12. 4\% compared to the current baseline \base. Using only 25\% of the complete dataset with BAL, we achieve LRMSE only 0.0165 higher than \base~and 0.0248 higher than our offline model (0.0583). In downstream flux matching applications, our NN surrogate provides 45x speedup over TGLF while maintaining comparable accuracy, demonstrating potential for training efficient surrogates for higher-fidelity models where data acquisition is costly and sparse.

Calibrating agent-based epidemic models is computationally demanding. We present a supervised machine learning calibrator that learns the inverse mapping from epidemic time series to SIR parameters. A three-layer bidirectional LSTM ingests 60-day incidence together with population size and recovery rate, and outputs transmission probability, contact rate, and R0. Training uses a composite loss with an epidemiology-motivated consistency penalty that encourages R0 \* recovery rate to equal transmission probability \* contact rate. In a 1000-scenario simulation study, we compare the calibrator with Approximate Bayesian Computation (likelihood-free MCMC). The method achieves lower error across all targets (MAE: R0 0.0616 vs 0.275; transmission 0.0715 vs 0.128; contact 1.02 vs 4.24), produces tighter predictive intervals with near nominal coverage, and reduces wall clock time from 77.4 s to 2.35 s per calibration. Although contact rate and transmission probability are partially nonidentifiable, the approach reproduces epidemic curves more faithfully than ABC, enabling fast and practical calibration. We evaluate it on SIR agent based epidemics generated with epiworldR and provide an implementation in R.

Recent advances in neural density estimation have enabled powerful simulation-based inference (SBI) methods that can flexibly approximate Bayesian inference for intractable stochastic models. Although these methods have demonstrated reliable posterior estimation when the simulator accurately represents the underlying data generative process (GDP), recent work has shown that they perform poorly in the presence of model misspecification. This poses a significant problem for their use on real-world problems, due to simulators always misrepresenting the true DGP to a certain degree. In this paper, we introduce robust variational neural posterior estimation (R VNP), a method which addresses the problem of misspecification in amortised SBI by bridging the simulation-to-reality gap using variational inference and error modelling. We test R VNP on multiple benchmark tasks, including using real data from astronomy, and show that it can recover robust posterior inference in a data-driven manner without adopting tunable hyperparameters or priors governing the misspecification.

Cryo-electron microscopy (Cryo-EM) enables high-resolution imaging of biomolecules, but structural heterogeneity remains a major challenge in 3D reconstruction. Traditional methods assume a discrete set of conformations, limiting their ability to recover continuous structural variability. In this work, we formulate cryo-EM reconstruction as a stochastic inverse problem (SIP) over probability measures, where the observed images are modeled as the push-forward of an unknown distribution over molecular structures via a random forward operator. We pose the reconstruction problem as the minimization of a variational discrepancy between observed and simulated image distributions, using statistical distances such as the KL divergence and the Maximum Mean Discrepancy. The resulting optimization is performed over the space of probability measures via a Wasserstein gradient flow, which we numerically solve using particles to represent and evolve conformational ensembles. We validate our approach using synthetic examples, including a realistic protein model, which demonstrates its ability to recover continuous distributions over structural states. We analyze the connection between our formulation and Maximum A Posteriori (MAP) approaches, which can be interpreted as instances of the discretize-then-optimize (DTO) framework. We further provide a consistency analysis, establishing conditions under which DTO methods, such as MAP estimation, converge to the solution of the underlying infinite-dimensional continuous problem. Beyond cryo-EM, the framework provides a general methodology for solving SIPs involving random forward operators.

In-context operator networks (ICON) are a class of operator learning methods based on the novel architectures of foundation models. Trained on a diverse set of datasets of initial and boundary conditions paired with corresponding solutions to ordinary and partial differential equations (ODEs and PDEs), ICON learns to map example condition-solution pairs of a given differential equation to an approximation of its solution operator. Here, we present a probabilistic framework that reveals ICON as implicitly performing Bayesian inference, where it computes the mean of the posterior predictive distribution over solution operators conditioned on the provided context, i.e., example condition-solution pairs. The formalism of random differential equations provides the probabilistic framework for describing the tasks ICON accomplishes while also providing a basis for understanding other multi-operator learning methods. This probabilistic perspective provides a basis for extending ICON to \emph{generative} settings, where one can sample from the posterior predictive distribution of solution operators. The generative formulation of ICON (GenICON) captures the underlying uncertainty in the solution operator, which enables principled uncertainty quantification in the solution predictions in operator learning.

--Nonnegative matrix factorization (NMF) is a known unsupervised data-reduction method. The principle of the common cause (PCC) is a basic methodological approach in probabilistic causality, which seeks an independent mixture model for the joint probability of two dependent random variables. It turns out that these two concepts are closely related. This relationship is explored reciprocally for several datasets of gray-scale images, which are conveniently mapped into probability models. On one hand, PCC provides a predictability tool that leads to a robust estimation of the effective rank of NMF . Unlike other estimates (e.g., those based on the Bayesian Information Criteria), our estimate of the rank is stable against weak noise. We show that NMF implemented around this rank produces features (basis images) that are also stable against noise and against seeds of local optimization, thereby effectively resolving the NMF nonidentifiability problem. On the other hand, NMF provides an interesting possibility of implementing PCC in an approximate way, where larger and positively correlated joint probabilities tend to be explained better via the independent mixture model. We work out a clustering method, where data points with the same common cause are grouped into the same cluster . We also show how NMF can be employed for data denoising. Nonnegative matrix factorization (NMF) was proposed and developed in data science [1]-[3].

Abstract--As long-endurance and seafloor-resident AUVs become more capable, there is an increasing need for extended, real-time interpretation of seafloor imagery to enable adaptive missions and optimise communication efficiency. Although offline image analysis methods are well established, they rely on access to complete datasets and human-labelled examples to manage the strong influence of environmental and operational conditions on seafloor image appearance--requirements that cannot be met in real-time settings. T o address this, we introduce an online clustering framework (OCF) capable of interpreting seafloor imagery without supervision, that is designed to operate in real-time on continuous data streams in a scalable, adaptive, and self-consistent manner . The method enables the efficient review and consolidation of common patterns across the entire data history in constant time by identifying and maintaining a set of representative samples that capture the evolving feature distribution, supporting dynamic cluster merging and splitting without reprocessing the full image history. We evaluate the framework on three diverse seafloor image datasets, analysing the impact of different representative sampling strategies on both clustering accuracy and computational cost. The OCF achieves the highest average F1 score of 0.68 across the three datasets among all comparative online clustering approaches, with a standard deviation of 3% across three distinct survey trajectories, demonstrating its superior clustering capability and robustness to trajectory variation. In addition, it maintains consistently lower and bounded computational time as the data volume increases. Compared to offline clustering methods, it strikes a favourable balance between accuracy and efficiency. These properties are beneficial for generating survey data summaries and supporting informative path planning in long-term, persistent autonomous marine exploration.