It is often stated in papers tackling the task of inferring Bayesian network structures from data that there are these two distinct approaches: (i) Apply conditional independence tests when testing for the presence or otherwise of edges; (ii) Search the model space using a scoring metric. Here I argue that for complete data and a given node ordering this division is a myth, by showing that cross entropy methods for checking conditional independence are mathematically identical to methods based upon discriminating between models by their overall goodness-of-fit logarithmic scores.

We present two sampling algorithms for probabilistic confidence inference in Bayesian networks. These two algorithms (we call them AIS-BN-mu and AIS-BN-sigma algorithms) guarantee that estimates of posterior probabilities are with a given probability within a desired precision bound. Our algorithms are based on recent advances in sampling algorithms for (1) estimating the mean of bounded random variables and (2) adaptive importance sampling in Bayesian networks. In addition to a simple stopping rule for sampling that they provide, the AIS-BN-mu and AIS-BN-sigma algorithms are capable of guiding the learning process in the AIS-BN algorithm. An empirical evaluation of the proposed algorithms shows excellent performance, even for very unlikely evidence.

An instrument is a random variable thatallows the identification of parameters inlinear models when the error terms arenot uncorrelated.It is a popular method used in economicsand the social sciences that reduces theproblem of identification to the problemof finding the appropriate instruments.Few years ago, Pearl introduced a necessarytest for instruments that allows the researcher to discard those candidatesthat fail the test.In this paper, we make a detailed study of Pearl's test and the general model forinstruments. The results of this studyinclude a novel interpretation of Pearl'stest, a general theory of instrumentaltests, and an affirmative answer to aprevious conjecture. We also presentnew instrumentality tests for the casesof discrete and continuous variables.

We present a general framework for defining priors on model structure and sampling from the posterior using the Metropolis-Hastings algorithm. The key idea is that structure priors are defined via a probability tree and that the proposal mechanism for the Metropolis-Hastings algorithm operates by traversing this tree, thereby defining a cheaply computable acceptance probability. We have applied this approach to Bayesian net structure learning using a number of priors and tree traversal strategies. Our results show that these must be chosen appropriately for this approach to be successful.

In the modern healthcare system, rapidly expanding costs/complexity, the growing myriad of treatment options, and exploding information streams that often do not effectively reach the front lines hinder the ability to choose optimal treatment decisions over time. The goal in this paper is to develop a general purpose (non-disease-specific) computational/artificial intelligence (AI) framework to address these challenges. This serves two potential functions: 1) a simulation environment for exploring various healthcare policies, payment methodologies, etc., and 2) the basis for clinical artificial intelligence - an AI that can think like a doctor. This approach combines Markov decision processes and dynamic decision networks to learn from clinical data and develop complex plans via simulation of alternative sequential decision paths while capturing the sometimes conflicting, sometimes synergistic interactions of various components in the healthcare system. It can operate in partially observable environments (in the case of missing observations or data) by maintaining belief states about patient health status and functions as an online agent that plans and re-plans. This framework was evaluated using real patient data from an electronic health record. Such an AI framework easily outperforms the current treatment-as-usual (TAU) case-rate/fee-for-service models of healthcare (Cost per Unit Change: $189 vs. $497) while obtaining a 30-35% increase in patient outcomes. Tweaking certain model parameters further enhances this advantage, obtaining roughly 50% more improvement for roughly half the costs. Given careful design and problem formulation, an AI simulation framework can approximate optimal decisions even in complex and uncertain environments. Future work is described that outlines potential lines of research and integration of machine learning algorithms for personalized medicine.

In this work we propose a heteroscedastic generalization to RVM, a fast Bayesian framework for regression, based on some recent similar works. We use variational approximation and expectation propagation to tackle the problem. The work is still under progress and we are examining the results and comparing with the previous works.

We present some nonparametric methods for graphical modeling. In the discrete case, where the data are binary or drawn from a finite alphabet, Markov random fields are already essentially nonparametric, since the cliques can take only a finite number of values. Continuous data are different. The Gaussian graphical model is the standard parametric model for continuous data, but it makes distributional assumptions that are often unrealistic. We discuss two approaches to building more flexible graphical models. One allows arbitrary graphs and a nonparametric extension of the Gaussian; the other uses kernel density estimation and restricts the graphs to trees and forests. Examples of both methods are presented. We also discuss possible future research directions for nonparametric graphical modeling.

Role mining tackles the problem of finding a role-based access control (RBAC) configuration, given an access-control matrix assigning users to access permissions as input. Most role mining approaches work by constructing a large set of candidate roles and use a greedy selection strategy to iteratively pick a small subset such that the differences between the resulting RBAC configuration and the access control matrix are minimized. In this paper, we advocate an alternative approach that recasts role mining as an inference problem rather than a lossy compression problem. Instead of using combinatorial algorithms to minimize the number of roles needed to represent the access-control matrix, we derive probabilistic models to learn the RBAC configuration that most likely underlies the given matrix. Our models are generative in that they reflect the way that permissions are assigned to users in a given RBAC configuration. We additionally model how user-permission assignments that conflict with an RBAC configuration emerge and we investigate the influence of constraints on role hierarchies and on the number of assignments. In experiments with access-control matrices from real-world enterprises, we compare our proposed models with other role mining methods. Our results show that our probabilistic models infer roles that generalize well to new system users for a wide variety of data, while other models' generalization abilities depend on the dataset given.

In this paper we extend temporal difference policy evaluation algorithms to performance criteria that include the variance of the cumulative reward. Such criteria are useful for risk management, and are important in domains such as finance and process control. We propose both TD(0) and LSTD(lambda) variants with linear function approximation, prove their convergence, and demonstrate their utility in a 4-dimensional continuous state space problem.

Formal exploration approaches in model-based reinforcement learning estimate the accuracy of the currently learned model without consideration of the empirical prediction error. For example, PAC-MDP approaches such as Rmax base their model certainty on the amount of collected data, while Bayesian approaches assume a prior over the transition dynamics. We propose extensions to such approaches which drive exploration solely based on empirical estimates of the learner's accuracy and learning progress. We provide a ``sanity check'' theoretical analysis, discussing the behavior of our extensions in the standard stationary finite state-action case. We then provide experimental studies demonstrating the robustness of these exploration measures in cases of non-stationary environments or where original approaches are misled by wrong domain assumptions.