Developing knowledge-driven contemporaneous health index (CHI) that can precisely reflect the underlying patient across the course of the condition's progression holds a unique value, like facilitating a range of clinical decision-making opportunities. This is particularly important for monitoring degenerative condition such as Alzheimer's disease (AD), where the condition of the patient will decay over time. Detecting early symptoms and progression sign, and continuous severity evaluation, are all essential for disease management. While a few methods have been developed in the literature, uncertainty quantification of those health index models has been largely neglected. To ensure the continuity of the care, we should be more explicit about the level of confidence in model outputs. Ideally, decision-makers should be provided with recommendations that are robust in the face of substantial uncertainty about future outcomes. In this paper, we aim at filling this gap by developing an uncertainty quantification based contemporaneous longitudinal index, named UQ-CHI, with a particular focus on continuous patient monitoring of degenerative conditions. Our method is to combine convex optimization and Bayesian learning using the maximum entropy learning (MEL) framework, integrating uncertainty on labels as well. Our methodology also provides closed-form solutions in some important decision making tasks, e.g., such as predicting the label of a new sample. Numerical studies demonstrate the effectiveness of the propose UQ-CHI method in prediction accuracy, monitoring efficacy, and unique advantages if uncertainty quantification is enabled practice.

Predicting the direction of assets have been an active area of study and a difficult task. Machine learning models have been used to build robust models to model the above task. Ensemble methods is one of them showing results better than a single supervised method. In this paper, we have used generative and discriminative classifiers to create the stack, particularly 3 generative and 9 discriminative classifiers and optimized over one-layer Neural Network to model the direction of price cryptocurrencies. Features used are technical indicators used are not limited to trend, momentum, volume, volatility indicators, and sentiment analysis has also been used to gain useful insight combined with the above features. For Cross-validation, Purged Walk forward cross-validation has been used. In terms of accuracy, we have done a comparative analysis of the performance of Ensemble method with Stacking and Ensemble method with blending. We have also developed a methodology for combined features importance for the stacked model. Important indicators are also identified based on feature importance.

Reinforcement learning (RL) typically defines a discount factor as part of the Markov Decision Process. The discount factor values future rewards by an exponential scheme that leads to theoretical convergence guarantees of the Bellman equation. However, evidence from psychology, economics and neuroscience suggests that humans and animals instead have hyperbolic time-preferences. In this work we revisit the fundamentals of discounting in RL and bridge this disconnect by implementing an RL agent that acts via hyperbolic discounting. We demonstrate that a simple approach approximates hyperbolic discount functions while still using familiar temporal-difference learning techniques in RL. Additionally, and independent of hyperbolic discounting, we make a surprising discovery that simultaneously learning value functions over multiple time-horizons is an effective auxiliary task which often improves over a strong value-based RL agent, Rainbow.

In this paper, we propose a robust sequential learning strategy for training large-scale Recommender Systems (RS) over implicit feedback mainly in the form of clicks. Our approach relies on the minimization of a pairwise ranking loss over blocks of consecutive items constituted by a sequence of non-clicked items followed by a clicked one for each user. Parameter updates are discarded if for a given user the number of sequential blocks is below or above some given thresholds estimated over the distribution of the number of blocks in the training set. This is to prevent from an abnormal number of clicks over some targeted items, mainly due to bots; or very few user interactions. Both scenarios affect the decision of RS and imply a shift over the distribution of items that are shown to the users. We provide a theoretical analysis showing that in the case where the ranking loss is convex, the deviation between the loss with respect to the sequence of weights found by the proposed algorithm and its minimum is bounded. Furthermore, experimental results on five large-scale collections demonstrate the efficiency of the proposed algorithm with respect to the state-of-the-art approaches, both regarding different ranking measures and computation time.

We consider the problem of learning from sparse and underspecified rewards, where an agent receives a complex input, such as a natural language instruction, and needs to generate a complex response, such as an action sequence, while only receiving binary success-failure feedback. Such success-failure rewards are often underspecified: they do not distinguish between purposeful and accidental success. Generalization from underspecified rewards hinges on discounting spurious trajectories that attain accidental success, while learning from sparse feedback requires effective exploration. We address exploration by using a mode covering direction of KL divergence to collect a diverse set of successful trajectories, followed by a mode seeking KL divergence to train a robust policy. We propose Meta Reward Learning (MeRL) to construct an auxiliary reward function that provides more refined feedback for learning. The parameters of the auxiliary reward function are optimized with respect to the validation performance of a trained policy. The MeRL approach outperforms our alternative reward learning technique based on Bayesian Optimization, and achieves the state-of-the-art on weakly-supervised semantic parsing. It improves previous work by 1.2% and 2.4% on WikiTableQuestions and WikiSQL datasets respectively.

In many application settings, the data are plagued with missing features. These hinder data analysis. An abundant literature addresses missing values in an inferential framework, where the aim is to estimate parameters and their variance from incomplete tables. Here, we consider supervised-learning settings where the objective is to best predict a target when missing values appear in both training and test sets. We analyze which missing-values strategies lead to good prediction. We show the consistency of two approaches to estimating the prediction function. The most striking one shows that the widely-used mean imputation prior to learning method is consistent when missing values are not informative. This is in contrast with inferential settings as mean imputation is known to have serious drawbacks in terms of deformation of the joint and marginal distribution of the data. That such a simple approach can be consistent has important consequences in practice. This result holds asymptotically when the learning algorithm is consistent in itself. We contribute additional analysis on decision trees as they can naturally tackle empirical risk minimization with missing values. This is due to their ability to handle the half-discrete nature of variables with missing values. After comparing theoretically and empirically different missing-values strategies in trees, we recommend using the missing incorporated in attributes method as it can handle both non-informative and informative missing values.

Revenue management can enable airline corporations to maximize the revenue generated from each scheduled flight departing in their transportation network by means of finding the optimal policies for differential pricing, seat inventory control and overbooking. As different demand segments in the market have different Willingness-To-Pay (WTP), airlines use differential pricing, booking restrictions, and service amenities to determine different fare classes or products targeted at each of these demand segments. Because seats are limited for each flight, airlines also need to allocate seats for each of these fare classes to prevent lower fare class passengers from displacing higher fare class ones and set overbooking limits in anticipation of cancellations and no-shows such that revenue is maximized. Previous work addresses these problems using optimization techniques or classical Reinforcement Learning methods. This paper focuses on the latter problem - the seat inventory control problem - casting it as a Markov Decision Process to be able to find the optimal policy. Multiple fare classes, concurrent continuous arrival of passengers of different fare classes, overbooking and random cancellations that are independent of class have been considered in the model. We have addressed this problem using Deep Q-Learning with the goal of maximizing the reward for each flight departure. The implementation of this technique allows us to employ large continuous state space but also presents the potential opportunity to test on real time airline data. To generate data and train the agent, a basic air-travel market simulator was developed. The performance of the agent in different simulated market scenarios was compared against theoretically optimal solutions and was found to be nearly close to the expected optimal revenue.

Nowadays the increasing and rapid progress of technology and the availability of electronic documents from a variety of sources have made a huge amount of textual data available. Hence, one of the prominent research topics of statistical andmachine learning communities is to provide suitable and feasible methods to extract high-quality information from unstructured textual data (Lata and Loar, 2018) for the different purposes of clustering, classification and document retrieval (Khan et al., 2010). This work originates from an empirical problem of classification of the content ofcalls made to the customer service of an important mobile phone company inItaly. The received calls are written down by an operator and classified into relevant classes (e.g.

Bayesian network (BN) modelling is extensively used in systems epidemiology. Usually it consists in selecting and reporting the best-fitting structure conditional to the data. A major practical concern is avoiding overfitting, on account of its extreme flexibility and its modelling richness. Many approaches have been proposed to control for overfitting. Unfortunately, they essentially all rely on very crude decisions that result in too simplistic approaches for such complex systems. In practice, with limited data sampled from complex system, this approach seems too simplistic. An alternative would be to use the Monte Carlo Markov chain model choice (MC3) over the network to learn the landscape of reasonably supported networks, and then to present all possible arcs with their MCMC support. This paper presents an R implementation, called mcmcabn, of a flexible structural MC3 that is accessible to non-specialists.

Some machine learning applications require continual learning - where data comes in a sequence of datasets, each is used for training and then permanently discarded. From a Bayesian perspective, continual learning seems straightforward: Given the model posterior one would simply use this as the prior for the next task. However, exact posterior evaluation is intractable with many models, especially with Bayesian neural networks (BNNs). Instead, posterior approximations are often sought. Unfortunately, when posterior approximations are used, prior-focused approaches do not succeed in evaluations designed to capture properties of realistic continual learning use cases. As an alternative to prior-focused methods, we introduce a new approximate Bayesian derivation of the continual learning loss. Our loss does not rely on the posterior from earlier tasks, and instead adapts the model itself by changing the likelihood term. We call these approaches likelihood-focused. We then combine prior- and likelihood-focused methods into one objective, tying the two views together under a single unifying framework of approximate Bayesian continual learning.