When deploying machine learning estimators in science and engineering (SAE) domains, it is critical to avoid failed estimations that can have disastrous consequences, e.g., in aero engine design.

This generates two (possibly invalid) child molecules. If valid molecules exist, the we choose one of them randomly. Details of seven different ways of modifying a molecule are as follows. The atom_addition connects a new atom to a single atom. The atom_insertion puts an atom between two atoms.

MetaBox offers a flexible algorithmic template that allows users to effortlessly implement their unique designs within the platform.

These have the opposite properties, with DRL having good sample efficiencyandpoor stability, while ESbeing vice versa. Recently,there havebeen attempts tocombine these algorithms, butthesemethods fullyrelyonsynchronous updatescheme, making it not ideal to maximize the benefits of the parallelism in ES.