A "meta-study" or "meta-analysis" analyzes multiple medical studies related to the same disease, treatment protocol, and outcome measurement to identify if there is an overall effect or not (e.g., treatment induces remission or causes adverse effects). It's advantage lies in the pooling and analysis of results across independent studies, which increases the population size, mitigates some experimental bias or inconsistent results from a single study, etc. Meta-studies are important for understanding the effectiveness (or not) of treatment, influencing clinical guidelines and for spurring new research directions. However, meta-studies are extremely time consuming to construct by hand and keep updated with the latest results. This limits both their breadth of coverage (since researchers will only invest the time for diseases they are interested in) and their practically. Yet, high-quality medical research is increasing at a staggering rate, and there is an opportunity to apply automation to this increasing body of knowledge, thereby expanding the benefits of meta-studies to (theoretically) all diseases and treatment, as they are published. That is, we envision, long term an automatic process for creating meta-studies across all diseases and treatments, and keeping those meta-studies up-to-date automatically. In this paper we demonstrate that there is potential to perform this task, point out future research directions to make this so, and, hopefully, spur significant interest in this compelling and important research direction at the intersection of medical research and machine learning.

Clinical practice guidelines (CPGs) were originally designed to help with evidence-based management of a single disease and such a single disease focus has impacted research on CPG computerization. This computerization is mostly concerned with supporting different representation formats and identifying potential inconsistencies in the definitions of CPGs. However, one of the biggest challenges facing physicians is the personalization of multiple CPGs to comorbid patients. Various research initiatives propose ways of mitigating adverse interactions in concurrently applied CPGs, however, there are no attempts to develop a generalized framework for mitigation that captures generic characteristics of the problem while handling nuances such as precedence relationships. In this paper we present our research towards developing a mitigation framework that relies on a first-order logic-based representation and related theorem proving and model finding techniques. The application of the proposed framework is illustrated with a simple clinical example.

This paper discusses how AI models of argumentation can play a role in personalized and participatory medicine. It describes our previous research on natural language generation of argumentation for genetic counseling and a pilot study on risk visualization, and our current research on argumentation mining.

A paradigm shift is taking place in the field of men- tal healthcare and patient wellbeing. Traditionally, the attempts at sustaining and enhancing wellbeing were mainly based on the comparison of the individual with the population average. Recently, attention has shifted towards a more personal, idiographic approach. Such shift calls for new solutions to get data about individu- als, create personalized models of wellbeing and trans- lating these into personalized advice. Idiographic research can be conducted on a large scale by letting people measure themselves. Repeated collec- tion of data, for example by means of questionnaires, provides individuals feedback on and insight into their wellbeing. A way to partially automate this feedback process is by creating software that statistically ana- lyzes, using a method known as vector autoregression, repetitive questionnaire data to determine cause-effect relationships between the measured features. In this pa- per we describe a means to facilitate these repetitive measurements and to partially automate the feedback process. The paper provides an overview and technical description of such automated analyses software, named Autovar, and its use in an online self-measurement plat- form.

Children with complex health conditions require care from a large, diverse set of caregivers that includes parents and community support organizations as well as multiple types of medical professionals. Coordination of their care is essential for good outcomes, and  extensive  research has shown that the use of integrated, team-based care plans improves care coordination. Care plans, however, are rarely deployed in practice. This paper describes barriers to effective implementation of care plans in complex care revealed by a study of care providers treating such children. It draws on teamwork theories, identifying ways AI capabilities could enhance care plan use; describes the design of GoalKeeper, a system to support providers use of care plans; and describes  initial work toward information sharing algorithms for such systems.

In this paper we present a novel agent-based modeling methodology to predict rooftop solar adoptions in the residential energy market. We first applied several linear regression models to estimate missing variables for non-adopters, so that attributes of non-adopters and adopters could be used to train a logistic regression model. Then, we integrated the logistic regression model along with other predictive models into a multi-agent simulation platform and validated our models by comparing the forecast of aggregate adoptions in a typical zip code area with its ground truth. This result shows that the agent-based model can reliably predict future adoptions. Finally, based on the validated agent-based model, we compared the outcome of a hypothesized seeding policy with the original incentive plan, and investigated other alternative seeding policies which could lead to more adopters.

The tight long-run fit of the learning curve has led to its use as a tool to predict the future cost of solar panels. Nemet (2006) is skeptical of the view that learning has been an important driver of cost reduction, and uses data during 1975-2002 to show that increases in plant size has been the most important driver of reduction in cost per watt.

Behavioral scientists contend that individuals, and organizations rarely make decisions solely on the basis of economic factors. Decisions are also shaped by perceived risk, social interactions, currency and salience of information, and other value propositions. Social diffusion of information on consumer experiences, entrance of new business models better aligned with customers’ concerns when evaluating investments, and perceived improving economic conditions are all factors in consumers’ decisions to adopt a new technology, such as solar photovoltaics (PV). We describe a new conceptual agent-based model, BE-Solar, that incorporates a social and behavioral decision framework for technology adoption decisions. We demonstrate the feasibility of including heterogeneity and behavioral factors into an agent-based model of the solar PV market, which is being applied to the Southern California market.

An important contribution of our work is to quantitatively The SunShot Initiative (Sunshot 2011) has the goal of reducing assess the impact of peer effects on PV adoption in relationship the total costs for photovoltaic (PV) solar energy systems to other economic and non-economic variables. It has to be "cost-competitive" with other forms of energy. At that long been noted that peer effects play a significant role in cost, PV could be widely adopted and thus allow the United the adoption of new technology. For instance, (Rogers 2003) States (US) increase it's use of clean energy - a goal of the highlights the importance of "opinion leaders" and interpersonal Department of Energy (U.S.

Using geospatial methods, this paper informs the evolving field of research on the diffusion of residential Third Party Owned PV systems by analyzing 1) the spatial distribution of TPO systems, and 2) the influence of demographics on the adoption on the local level. This research is part of a multidisciplinary study into the diffusion of solar technology (SEEDS), using San Diego County as focus area. Our findings reveal a significant clustering of TPO PV adoption in San Diego County. TPO systems reached a similarly high market share across a large area in the central county in contrast to the installation of host-owned systems, which have been less evenly distributed across single-family households in the same area. The diffusion of TPO systems in San Diego County can be partially explained by looking at median income and percentage of people born in the US. The explanatory power of the model varies across the region.