A system is presented that segments, clusters and predicts musical audio in an unsupervised manner, adjusting the number of (timbre) clusters instantaneously to the audio input. A sequence learning algorithm adapts its structure to a dynamically changing clustering tree. The flow of the system is as follows: 1) segmentation by onset detection, 2) timbre representation of each segment by Mel frequency cepstrum coefficients, 3) discretization by incremental clustering, yielding a tree of different sound classes (e.g. instruments) that can grow or shrink on the fly driven by the instantaneous sound events, resulting in a discrete symbol sequence, 4) extraction of statistical regularities of the symbol sequence, using hierarchical N-grams and the newly introduced conceptual Boltzmann machine, and 5) prediction of the next sound event in the sequence. The system's robustness is assessed with respect to complexity and noisiness of the signal. Clustering in isolation yields an adjusted Rand index (ARI) of 82.7% / 85.7% for data sets of singing voice and drums. Onset detection jointly with clustering achieve an ARI of 81.3% / 76.3% and the prediction of the entire system yields an ARI of 27.2% / 39.2%.

A mixture of factor analyzers is a semi-parametric density estimator that generalizes the well-known mixtures of Gaussians model by allowing each Gaussian in the mixture to be represented in a different lower-dimensional manifold. This paper presents a robust and parsimonious model selection algorithm for training a mixture of factor analyzers, carrying out simultaneous clustering and locally linear, globally nonlinear dimensionality reduction. Permitting different number of factors per mixture component, the algorithm adapts the model complexity to the data complexity. We compare the proposed algorithm with related automatic model selection algorithms on a number of benchmarks. The results indicate the effectiveness of this fast and robust approach in clustering, manifold learning and class-conditional modeling.

Natural signals and images are well-known to be approximately sparse in transform domains such as Wavelets and DCT. This property has been heavily exploited in various applications in image processing and medical imaging. Compressed sensing exploits the sparsity of images or image patches in a transform domain or synthesis dictionary to reconstruct images from undersampled measurements. In this work, we focus on blind compressed sensing, where the underlying sparsifying transform is a priori unknown, and propose a framework to simultaneously reconstruct the underlying image as well as the sparsifying transform from highly undersampled measurements. The proposed block coordinate descent type algorithms involve highly efficient optimal updates. Importantly, we prove that although the proposed blind compressed sensing formulations are highly nonconvex, our algorithms are globally convergent (i.e., they converge from any initialization) to the set of critical points of the objectives defining the formulations. These critical points are guaranteed to be at least partial global and partial local minimizers. The exact point(s) of convergence may depend on initialization. We illustrate the usefulness of the proposed framework for magnetic resonance image reconstruction from highly undersampled k-space measurements. As compared to previous methods involving the synthesis dictionary model, our approach is much faster, while also providing promising reconstruction quality.

This paper addresses the problem of filtering with a state-space model. Standard approaches for filtering assume that a probabilistic model for observations (i.e. the observation model) is given explicitly or at least parametrically. We consider a setting where this assumption is not satisfied; we assume that the knowledge of the observation model is only provided by examples of state-observation pairs. This setting is important and appears when state variables are defined as quantities that are very different from the observations. We propose Kernel Monte Carlo Filter, a novel filtering method that is focused on this setting. Our approach is based on the framework of kernel mean embeddings, which enables nonparametric posterior inference using the state-observation examples. The proposed method represents state distributions as weighted samples, propagates these samples by sampling, estimates the state posteriors by Kernel Bayes' Rule, and resamples by Kernel Herding. In particular, the sampling and resampling procedures are novel in being expressed using kernel mean embeddings, so we theoretically analyze their behaviors. We reveal the following properties, which are similar to those of corresponding procedures in particle methods: (1) the performance of sampling can degrade if the effective sample size of a weighted sample is small; (2) resampling improves the sampling performance by increasing the effective sample size. We first demonstrate these theoretical findings by synthetic experiments. Then we show the effectiveness of the proposed filter by artificial and real data experiments, which include vision-based mobile robot localization.

We propose a novel method for multiple clustering that assumes a co-clustering structure (partitions in both rows and columns of the data matrix) in each view. The new method is applicable to high-dimensional data. It is based on a nonparametric Bayesian approach in which the number of views and the number of feature-/subject clusters are inferred in a data-driven manner. We simultaneously model different distribution families, such as Gaussian, Poisson, and multinomial distributions in each cluster block. This makes our method applicable to datasets consisting of both numerical and categorical variables, which biomedical data typically do. Clustering solutions are based on variational inference with mean field approximation. We apply the proposed method to synthetic and real data, and show that our method outperforms other multiple clustering methods both in recovering true cluster structures and in computation time. Finally, we apply our method to a depression dataset with no true cluster structure available, from which useful inferences are drawn about possible clustering structures of the data.

In many applications, such as text processing, computer vision or biology, data is represented as very highdimensional but sparse vectors. The ability to compute meaningful similarity scores between these objects is crucial to many tasks, such as classification, clustering or ranking. However, handcrafting a relevant similarity measure for such data is challenging because it is usually the case that only a small, often unknown subset of features is actually relevant to the task at hand. For instance, in drug discovery, chemical compounds can be represented as sparse features describing their 3D properties, and only a few of them play an role in determining whether the compound will bind to a target receptor (Guyon et al., 2004). In text classification, where each document is represented as a sparse bag of words, only a small subset of the words is generally sufficient to discriminate among documents of different topics. A principled way to obtain a similarity measure tailored to the problem of interest is to learn it from data. This line of research, known as similarity and distance metric learning, has been successfully applied to many application domains (see Kulis, 2012; Bellet et al., 2013, for recent surveys). The basic idea is to learn the parameters of a similarity (or distance) function such that it satisfies proximity-based constraints, requiring for instance that some data instance x be more similar to y than to z according to the learned function.

The application of existing methods for constructing optimal dynamic treatment regimes is limited to cases where investigators are interested in optimizing a utility function over a fixed period of time (finite horizon). In this manuscript, we develop an inferential procedure based on temporal difference residuals for optimal dynamic treatment regimes in infinite-horizon settings, where there is no a priori fixed end of follow-up point. The proposed method can be used to determine the optimal regime in chronic diseases where patients are monitored and treated throughout their life. We derive large sample results necessary for conducting inference. We also simulate a cohort of patients with diabetes to mimic the third wave of the National Health and Nutrition Examination Survey, and we examine the performance of the proposed method in controlling the level of hemoglobin A1c. Supplementary materials for this article are available online.

Max-convolution is an important problem closely resembling standard convolution; as such, max-convolution occurs frequently across many fields. Here we extend the method with fastest known worst-case runtime, which can be applied to nonnegative vectors by numerically approximating the Chebyshev norm $\| \cdot \|_\infty$, and use this approach to derive two numerically stable methods based on the idea of computing $p$-norms via fast convolution: The first method proposed, with runtime in $O( k \log(k) \log(\log(k)) )$ (which is less than $18 k \log(k)$ for any vectors that can be practically realized), uses the $p$-norm as a direct approximation of the Chebyshev norm. The second approach proposed, with runtime in $O( k \log(k) )$ (although in practice both perform similarly), uses a novel null space projection method, which extracts information from a sequence of $p$-norms to estimate the maximum value in the vector (this is equivalent to querying a small number of moments from a distribution of bounded support in order to estimate the maximum). The $p$-norm approaches are compared to one another and are shown to compute an approximation of the Viterbi path in a hidden Markov model where the transition matrix is a Toeplitz matrix; the runtime of approximating the Viterbi path is thus reduced from $O( n k^2 )$ steps to $O( n $k \log(k))$ steps in practice, and is demonstrated by inferring the U.S. unemployment rate from the S&P 500 stock index.

Acyclic digraphs are the underlying representation of Bayesian networks, a widely used class of probabilistic graphical models. Learning the underlying graph from data is a way of gaining insights about the structural properties of a domain. Structure learning forms one of the inference challenges of statistical graphical models. MCMC methods, notably structure MCMC, to sample graphs from the posterior distribution given the data are probably the only viable option for Bayesian model averaging. Score modularity and restrictions on the number of parents of each node allow the graphs to be grouped into larger collections, which can be scored as a whole to improve the chain's convergence. Current examples of algorithms taking advantage of grouping are the biased order MCMC, which acts on the alternative space of permuted triangular matrices, and non ergodic edge reversal moves. Here we propose a novel algorithm, which employs the underlying combinatorial structure of DAGs to define a new grouping. As a result convergence is improved compared to structure MCMC, while still retaining the property of producing an unbiased sample. Finally the method can be combined with edge reversal moves to improve the sampler further.

Principal component analysis (PCA) for binary data, known as logistic PCA, has become a popular alternative to dimensionality reduction of binary data. It is motivated as an extension of ordinary PCA by means of a matrix factorization, akin to the singular value decomposition, that maximizes the Bernoulli log-likelihood. We propose a new formulation of logistic PCA which extends Pearson's formulation of a low dimensional data representation with minimum error to binary data. Our formulation does not require a matrix factorization, as previous methods do, but instead looks for projections of the natural parameters from the saturated model. Due to this difference, the number of parameters does not grow with the number of observations and the principal component scores on new data can be computed with simple matrix multiplication. We derive explicit solutions for data matrices of special structure and provide computationally efficient algorithms for solving for the principal component loadings. Through simulation experiments and an analysis of medical diagnoses data, we compare our formulation of logistic PCA to the previous formulation as well as ordinary PCA to demonstrate its benefits.