Industry
PRISM2: Unlocking Multi-Modal General Pathology AI with Clinical Dialogue
Vorontsov, Eugene, Shaikovski, George, Casson, Adam, Viret, Julian, Zimmermann, Eric, Tenenholtz, Neil, Wang, Yi Kan, Bernhard, Jan H., Godrich, Ran A., Retamero, Juan A., Shia, Jinru, Gonen, Mithat, Weiser, Martin R., Klimstra, David S., Yousfi, Razik, Fusi, Nicolo, Fuchs, Thomas J., Severson, Kristen, Liu, Siqi
Recent rapid progress in the field of computational pathology has been enabled by foundation models. These models are beginning to move beyond encoding image patches towards whole-slide understanding but their clinical utility remains limited. In this work, we present PRISM2, a multimodal slide-level foundation model trained on data from 700,000 diagnostic specimen-report pairs, the largest vision (2.3 million whole slide images) and language (14M question-answer pairs) histopathology dataset to date. By learning through clinical-dialogue supervision, PRISM2 aligns histomorphologic features with the language of diagnostic reasoning, producing slide-level representations that support both direct diagnostic question-answering and transferable embeddings for downstream tasks. Without additional training, PRISM2 matches or exceeds the cancer-detection performance of clinical-grade products. This is observed without loss of generality on other tasks, where PRISM2 achieves top performance. Finally, using survival prediction as the example, we show that task-specific finetuning with a large dataset can outperform task-specific models, further improving performance. These results demonstrate how language-supervised pretraining provides a scalable, clinically grounded signal for learning generalizable pathology representations, bridging human diagnostic reasoning and foundation-model performance.
LiteVLM: A Low-Latency Vision-Language Model Inference Pipeline for Resource-Constrained Environments
Huang, Jin, Jin, Yuchao, An, Le, Park, Josh
This paper introduces an efficient Vision-Language Model (VLM) pipeline specifically optimized for deployment on embedded devices, such as those used in robotics and autonomous driving. The pipeline significantly reduces the computational overhead by jointly leveraging patch selection to filter irrelevant camera views, a token selection module to reduce input sequence length for the LLM, and speculative decoding to accelerate token generation. Evaluation on the NVIDIA DRIVE Thor platform for automonous driving application, our pipeline achieves $2.5\times$ end-to-end latency reduction without compromising task accuracy. The speed-up further increases to $3.2\times$ when applying FP8 post-training quantization. These results demonstrate our pipeline as a viable solution for enabling real-time VLM deployment in resource-constrained environments.
Towards Robust Mathematical Reasoning
Luong, Thang, Hwang, Dawsen, Nguyen, Hoang H., Ghiasi, Golnaz, Chervonyi, Yuri, Seo, Insuk, Kim, Junsu, Bingham, Garrett, Lee, Jonathan, Mishra, Swaroop, Zhai, Alex, Hu, Clara Huiyi, Michalewski, Henryk, Kim, Jimin, Ahn, Jeonghyun, Bae, Junhwi, Song, Xingyou, Trinh, Trieu H., Le, Quoc V., Jung, Junehyuk
Finding the right north-star metrics is highly critical for advancing the mathematical reasoning capabilities of foundation models, especially given that existing evaluations are either too easy or only focus on getting correct short answers. To address these issues, we present IMO-Bench, a suite of advanced reasoning benchmarks, vetted by a panel of top specialists and that specifically targets the level of the International Mathematical Olympiad (IMO), the most prestigious venue for young mathematicians. IMO-AnswerBench first tests models on 400 diverse Olympiad problems with verifiable short answers. IMO-Proof Bench is the next-level evaluation for proof-writing capabilities, which includes both basic and advanced IMO level problems as well as detailed grading guidelines to facilitate automatic grading. These benchmarks played a crucial role in our historic achievement of the gold-level performance at IMO 2025 with Gemini Deep Think (Luong and Lockhart, 2025). Our model achieved 80.0% on IMO-AnswerBench and 65.7% on the advanced IMO-Proof Bench, surpassing the best non-Gemini models by large margins of 6.9% and 42.4% respectively. We also showed that autograders built with Gemini reasoning correlate well with human evaluations and construct IMO-GradingBench, with 1000 human gradings on proofs, to enable further progress in automatic evaluation of long-form answers. We hope that IMO-Bench will help the community towards advancing robust mathematical reasoning and release it at https://imobench.github.io/.
A Detailed Study on LLM Biases Concerning Corporate Social Responsibility and Green Supply Chains
Ontrup, Greta, Bush, Annika, Pauly, Markus, Aksoy, Meltem
Organizations increasingly use Large Language Models (LLMs) to improve supply chain processes and reduce environmental impacts. However, LLMs have been shown to reproduce biases regarding the prioritization of sustainable business strategies. Thus, it is important to identify underlying training data biases that LLMs pertain regarding the importance and role of sustainable business and supply chain practices. This study investigates how different LLMs respond to validated surveys about the role of ethics and responsibility for businesses, and the importance of sustainable practices and relations with suppliers and customers. Using standardized questionnaires, we systematically analyze responses generated by state-of-the-art LLMs to identify variations. We further evaluate whether differences are augmented by four organizational culture types, thereby evaluating the practical relevance of identified biases. The findings reveal significant systematic differences between models and demonstrate that organizational culture prompts substantially modify LLM responses. The study holds important implications for LLM-assisted decision-making in sustainability contexts.
Machine and Deep Learning for Indoor UWB Jammer Localization
Fard, Hamed, Kholghi, Mahsa, Groร, Benedikt, Wunder, Gerhard
Ultra-wideband (UWB) localization delivers centimeter-scale accuracy but is vulnerable to jamming attacks, creating security risks for asset tracking and intrusion detection in smart buildings. Although machine learning (ML) and deep learning (DL) methods have improved tag localization, localizing malicious jammers within a single room and across changing indoor layouts remains largely unexplored. Two novel UWB datasets, collected under original and modified room configurations, are introduced to establish comprehensive ML/DL baselines. Performance is rigorously evaluated using a variety of classification and regression metrics. On the source dataset with the collected UWB features, Random Forest achieves the highest F1-macro score of 0.95 and XGBoost achieves the lowest mean Euclidean error of 20.16 cm. However, deploying these source-trained models in the modified room layout led to severe performance degradation, with XGBoost's mean Euclidean error increasing tenfold to 207.99 cm, demonstrating significant domain shift. To mitigate this degradation, a domain-adversarial ConvNeXt autoencoder (A-CNT) is proposed that leverages a gradient-reversal layer to align CIR-derived features across domains. The A-CNT framework restores localization performance by reducing the mean Euclidean error to 34.67 cm. This represents a 77 percent improvement over non-adversarial transfer learning and an 83 percent improvement over the best baseline, restoring the fraction of samples within 30 cm to 0.56. Overall, the results demonstrate that adversarial feature alignment enables robust and transferable indoor jammer localization despite environmental changes. Code and dataset available at https://github.com/afbf4c8996f/Jammer-Loc
No-rank Tensor Decomposition Using Metric Learning
Tensor decomposition faces fundamental challenges in analyzing high-dimensional data, where traditional methods based on reconstruction and fixed-rank constraints often fail to capture semantically meaningful structures. This paper introduces a no-rank tensor decomposition framework grounded in metric learning, which replaces reconstruction objectives with a discriminative, similarity-based optimization. The proposed approach learns data-driven embeddings by optimizing a triplet loss with diversity and uniformity regularization, creating a feature space where distance directly reflects semantic similarity. We provide theoretical guarantees for the framework's convergence and establish bounds on its metric properties. Evaluations across diverse domains -- including face recognition (LFW, Olivetti), brain connectivity analysis (ABIDE), and simulated data (galaxy morphology, crystal structures) -- demonstrate that our method outperforms baseline techniques, including PCA, t-SNE, UMAP, and tensor decomposition baselines (CP and Tucker). Results show substantial improvements in clustering metrics (Silhouette Score, Davies-Bouldin Index, Calinski-Harabasz Index, Separation Ratio, Adjusted Rand Index, Normalized Mutual Information) and reveal a fundamental trade-off: while metric learning optimizes global class separation, it deliberately transforms local geometry to align with semantic relationships. Crucially, our approach achieves superior performance with smaller training datasets compared to transformer-based methods, offering an efficient alternative for domains with limited labeled data. This work establishes metric learning as a paradigm for tensor-based analysis, prioritizing semantic relevance over pixel-level fidelity while providing computational advantages in data-scarce scenarios.
How Far Are Surgeons from Surgical World Models? A Pilot Study on Zero-shot Surgical Video Generation with Expert Assessment
Chen, Zhen, Xu, Qing, Wu, Jinlin, Yang, Biao, Zhai, Yuhao, Guo, Geng, Zhang, Jing, Ding, Yinlu, Navab, Nassir, Luo, Jiebo
Foundation models in video generation are demonstrating remarkable capabilities as potential world models for simulating the physical world. However, their application in high-stakes domains like surgery, which demand deep, specialized causal knowledge rather than general physical rules, remains a critical unexplored gap. To systematically address this challenge, we present SurgVeo, the first expert-curated benchmark for video generation model evaluation in surgery, and the Surgical Plausibility Pyramid (SPP), a novel, four-tiered framework tailored to assess model outputs from basic appearance to complex surgical strategy. On the basis of the SurgVeo benchmark, we task the advanced Veo-3 model with a zero-shot prediction task on surgical clips from laparoscopic and neurosurgical procedures. A panel of four board-certified surgeons evaluates the generated videos according to the SPP. Our results reveal a distinct "plausibility gap": while Veo-3 achieves exceptional Visual Perceptual Plausibility, it fails critically at higher levels of the SPP, including Instrument Operation Plausibility, Environment Feedback Plausibility, and Surgical Intent Plausibility. This work provides the first quantitative evidence of the chasm between visually convincing mimicry and causal understanding in surgical AI. Our findings from SurgVeo and the SPP establish a crucial foundation and roadmap for developing future models capable of navigating the complexities of specialized, real-world healthcare domains.
RLAC: Reinforcement Learning with Adversarial Critic for Free-Form Generation Tasks
Wu, Mian, Zhang, Gavin, Min, Sewon, Levine, Sergey, Kumar, Aviral
Open-ended generation tasks require outputs to satisfy diverse and often implicit task-specific evaluation rubrics. The sheer number of relevant rubrics leads to prohibitively high verification costs and incomplete assessments of a response, making reinforcement learning (RL) post-training with rubric-based rewards difficult to scale. This problem is exacerbated by the fact that often the best way to combine these rubrics into one single reward is also highly prompt-specific. We propose Reinforcement Learning with Adversarial Critic (RLAC), a post-training approach that addresses these challenges via dynamic rubric verification. Our approach employs a large language model (LLM) as a critic that dynamically identifies only the most likely failure modes (e.g., a factual error or unhandled edge case), which are then verified by an external validator to optimize both generator and critic jointly. By training both the generator and the critic, this game enhances the critic's error detection and the generator's output quality while reducing required verifications. Our experiments demonstrate that RLAC improves factual accuracy in text generation and correctness in code generation, while also outperforming exhaustive verification and reward model methods. We show that dynamic critics are more effective than fixed critics, showcasing the potential of RLAC for scaling RL post-training to free-form generation tasks.
An Open-Access Benchmark of Statistical and Machine-Learning Anomaly Detection Methods for Battery Applications
Pang, Mei-Chin, Adhikari, Suraj, Kasahara, Takuma, Haba, Nagihiro, Ohno, Saneyuki
Battery safety is critical in applications ranging from consumer electronics to electric vehicles and aircraft, where undetected anomalies could trigger safety hazards or costly downtime. In this study, we present OSBAD as an open-source benchmark for anomaly detection frameworks in battery applications. By benchmarking 15 diverse algorithms encompassing statistical, distance-based, and unsupervised machine-learning methods, OSBAD enables a systematic comparison of anomaly detection methods across heterogeneous datasets. In addition, we demonstrate how a physics- and statistics-informed feature transformation workflow enhances anomaly separability by decomposing collective anomalies into point anomalies. To address a major bottleneck in unsupervised anomaly detection due to incomplete labels, we propose a Bayesian optimization pipeline that facilitates automated hyperparameter tuning based on transfer-learning and regression proxies. Through validation on datasets covering both liquid and solid-state chemistries, we further demonstrate the cross-chemistry generalization capability of OSBAD to identify irregularities across different electrochemical systems. By making benchmarking database with open-source reproducible anomaly detection workflows available to the community, OSBAD establishes a unified foundation for developing safe, scalable, and transferable anomaly detection tools in battery analytics. This research underscores the significance of physics- and statistics-informed feature engineering as well as model selection with probabilistic hyperparameter tuning, in advancing trustworthy, data-driven diagnostics for safety-critical energy systems.
Towards Efficient Federated Learning of Networked Mixture-of-Experts for Mobile Edge Computing
Gao, Song, Jing, Shusen, Zhang, Shuai, Wang, Yue, Zhou, Xiangwei, Zhang, Songyang
Abstract--Recent advancements in large artificial intelligence models (LAMs) are driving significant innovations in mobile edge computing within next-generation wireless networks. However, the substantial demands for computational resources and large-scale training data required to train LAMs conflict with the limited storage and computational capacity of edge devices, posing significant challenges to training and deploying LAMs at the edge. In this work, we introduce the Networked Mixture-of-Experts (NMoE) system, in which clients infer collaboratively by distributing tasks to suitable neighbors based on their expertise and aggregate the returned results. For training the NMoE, we propose a federated learning framework that integrates both supervised and self-supervised learning to balance per-sonalization and generalization, while preserving communication efficiency and data privacy. We conduct extensive experiments to demonstrate the efficacy of the proposed NMoE system, providing insights and benchmarks for the NMoE training algorithms. The recent wave of progress in large artificial intelligence models (LAMs) has triggered a variety of novel technologies, such as large language models (LLMs), vision-language models (VLMs), and artificial intelligence (AI) agents [1], which present exciting opportunities for next-generation wireless communications.