Abstract-- Reliable navigation in under-canopy agricultural environments remains a challenge due to GNSS unreliability, cluttered rows, and variable lighting. T o address these limitations, we present an end-to-end learning-based navigation system that maps raw 3D LiDAR data directly to control commands using a deep reinforcement learning policy trained entirely in simulation. Our method includes a voxel-based downsampling strategy that reduces LiDAR input size by 95.83%, enabling efficient policy learning without relying on labeled datasets or manually designed control interfaces. The policy was validated in simulation, achieving a 100% success rate in straight-row plantations and showing a gradual decline in performance as row curvature increased, tested across varying sinusoidal frequencies and amplitudes. Autonomous robots have seen significant growth in modern agriculture, particularly for under-canopy tasks such as plant phenotyping, crop row harvesting, and disease scouting. These applications require platforms that are not only compact and agile but also capable of accurately navigating between dense crop rows (Figure 1) [1]. However, reliable navigation in such environments remains an active area of research due to several challenges, including clutter and occlusions caused by narrow row spacing and the high visual variability introduced by different plant growth stages [2].

Major depressive disorder (MDD) is a prevalent mental health condition that negatively impacts both individual well-being and global public health. Automated detection of MDD using structural magnetic resonance imaging (sMRI) and deep learning (DL) methods holds increasing promise for improving diagnostic accuracy and enabling early intervention. Most existing methods employ either voxel-level features or handcrafted regional representations built from predefined brain atlases, limiting their ability to capture complex brain patterns. This paper develops a unified pipeline that utilizes Vision Transformers (ViTs) for extracting 3D region embeddings from sMRI data and Graph Neural Network (GNN) for classification. We explore two strategies for defining regions: (1) an atlas-based approach using predefined structural and functional brain atlases, and (2) an cube-based method by which ViTs are trained directly to identify regions from uniformly extracted 3D patches. Further, cosine similarity graphs are generated to model interregional relationships, and guide GNN-based classification. Extensive experiments were conducted using the REST-meta-MDD dataset to demonstrate the effectiveness of our model. With stratified 10-fold cross-validation, the best model obtained 81.51\% accuracy, 85.94\% sensitivity, 76.36\% specificity, 80.88\% precision, and 83.33\% F1-score. Further, atlas-based models consistently outperformed the cube-based approach, highlighting the importance of using domain-specific anatomical priors for MDD detection.

Abstract--We address automotive odometry for low-speed driving and parking, where centimeter-level accuracy is required due to tight spaces and nearby obstacles. Traditional methods using inertial-measurement units and wheel encoders require vehicle-specific calibration, making them costly for consumer-grade vehicles. T o overcome this, we propose a radar-based simultaneous localization and mapping (SLAM) approach that fuses inertial and 4D radar measurements. Our approach tightly couples feature positions and Doppler velocities for accurate localization and robust data association. Key contributions include a tightly coupled radar-Doppler extended Kalman filter, multi-radar support and an information-based feature-pruning strategy. Experiments using both proprietary and public datasets demonstrate high-accuracy localization during low-speed driving. Accurate relative localization is critical for automated parking applications, where the vehicle executes low-speed maneuvers in complex environments. Unlike highway or urban driving, parking scenarios demand centimeter-level accuracy due to space constraints and the proximity to surrounding obstacles.

Recent advances in agent development have focused on scaling model size and raw interaction data, mirroring successes in large language models. However, for complex, long-horizon multi-agent tasks such as robotic soccer, this end-to-end approach often fails due to intractable exploration spaces and sparse rewards. We propose that an effective world model for decision-making must model the world's physics and also its task semantics. A systematic review of 2024 research in low-resource multi-agent soccer reveals a clear trend towards integrating symbolic and hierarchical methods, such as Hierarchical Task Networks (HTNs) and Bayesian Strategy Networks (BSNs), with multi-agent reinforcement learning (MARL). These methods decompose complex goals into manageable subgoals, creating an intrinsic curriculum that shapes agent learning. We formalize this trend into a framework for Hierarchical Task Environments (HTEs), which are essential for bridging the gap between simple, reactive behaviors and sophisticated, strategic team play. Our framework incorporates the use of Large Language Models (LLMs) as generative world models of tasks, capable of dynamically generating this scaffolding. We argue that HTEs provide a mechanism to guide exploration, generate meaningful learning signals, and train agents to internalize hierarchical structure, enabling the development of more capable and general-purpose agents with greater sample efficiency than purely end-to-end approaches.

The capacity of an embodied agent to understand, predict, and interact with its environment is fundamentally contingent on an internal world model. This paper introduces a novel framework for investigating the formation and adaptation of such world models within a biological substrate: human neural organoids. We present a curriculum of three scalable, closed-loop virtual environments designed to train these biological agents and probe the underlying synaptic mechanisms of learning, such as long-term potentiation (LTP) and long-term depression (LTD). We detail the design of three distinct task environments that demand progressively more sophisticated world models for successful decision-making: (1) a conditional avoidance task for learning static state-action contingencies, (2) a one-dimensional predator-prey scenario for goal-directed interaction, and (3) a replication of the classic Pong game for modeling dynamic, continuous-time systems. For each environment, we formalize the state and action spaces, the sensory encoding and motor decoding mechanisms, and the feedback protocols based on predictable (reward) and unpredictable (punishment) stimulation, which serve to drive model refinement. In a significant methodological advance, we propose a meta-learning approach where a Large Language Model automates the generative design and optimization of experimental protocols, thereby scaling the process of environment and curriculum design. Finally, we outline a multi-modal evaluation strategy that moves beyond task performance to directly measure the physical correlates of the learned world model by quantifying synaptic plasticity at electrophysiological, cellular, and molecular levels. This work bridges the gap between model-based reinforcement learning and computational neuroscience, offering a unique platform for studying embodiment, decision-making, and the physical basis of intelligence.

Lexical alignment, where speakers start to use similar words across conversation, is known to contribute to successful communication. However, its implementation in conversational agents remains underexplored, particularly considering the recent advancements in large language models (LLMs). As a first step towards enabling lexical alignment in human-agent dialogue, this study draws on strategies for personalising conversational agents and investigates the construction of stable, personalised lexical profiles as a basis for lexical alignment. Specifically, we varied the amounts of transcribed spoken data used for construction as well as the number of items included in the profiles per part-of-speech (POS) category and evaluated profile performance across time using recall, coverage, and cosine similarity metrics. It was shown that smaller and more compact profiles, created after 10 min of transcribed speech containing 5 items for adjectives, 5 items for conjunctions, and 10 items for adverbs, nouns, pronouns, and verbs each, offered the best balance in both performance and data efficiency. In conclusion, this study offers practical insights into constructing stable, personalised lexical profiles, taking into account minimal data requirements, serving as a foundational step toward lexical alignment strategies in conversational agents.

The advancement of general-purpose intelligent agents is intrinsically linked to the environments in which they are trained. While scaling models and datasets has yielded remarkable capabilities, scaling the complexity, diversity, and interactivity of environments remains a crucial bottleneck. Hand-crafted environments are finite and often contain implicit biases, limiting the potential for agents to develop truly generalizable and robust skills. In this work, we propose a paradigm for generating a boundless and adaptive curriculum of challenges by framing the environment generation process as an adversarial game. We introduce a system where a team of cooperative multi-agent defenders learns to survive against a procedurally generative attacker. The attacker agent learns to produce increasingly challenging configurations of enemy units, dynamically creating novel worlds tailored to exploit the defenders' current weaknesses. Concurrently, the defender team learns cooperative strategies to overcome these generated threats. This co-evolutionary dynamic creates a self-scaling environment where complexity arises organically from the adversarial interaction, providing an effectively infinite stream of novel and relevant training data. We demonstrate that with minimal training, this approach leads to the emergence of complex, intelligent behaviors, such as flanking and shielding by the attacker, and focus-fire and spreading by the defenders. Our findings suggest that adversarial co-evolution is a powerful mechanism for automatically scaling environmental complexity, driving agents towards greater robustness and strategic depth.

Structure-based drug design (SBDD), aiming to generate 3D molecules with high binding affinity toward target proteins, is a vital approach in novel drug discovery. Although recent generative models have shown great potential, they suffer from unstable probability dynamics and mismatch between generated molecule size and the protein pockets geometry, resulting in inconsistent quality and off-target effects. We propose PAFlow, a novel target-aware molecular generation model featuring prior interaction guidance and a learnable atom number predictor. PAFlow adopts the efficient flow matching framework to model the generation process and constructs a new form of conditional flow matching for discrete atom types. A protein-ligand interaction predictor is incorporated to guide the vector field toward higher-affinity regions during generation, while an atom number predictor based on protein pocket information is designed to better align generated molecule size with target geometry. Extensive experiments on the CrossDocked2020 benchmark show that PAFlow achieves a new state-of-the-art in binding affinity (up to -8.31 Avg. Vina Score), simultaneously maintains favorable molecular properties.

City streets, sidewalks, and public areas often serve as primary interaction points among diverse user groups, including residents, commuters, and visitors ( Gehl, 2011). These spaces carry social, economic, and cultural signifi - cance that influences navigation and user experience ( Mitra ˇ sinovi c & Mehta, 2021). Municipal governments and planning agencies recognize the importance of inclusive public spaces but face challenges in operation - alizing inclusivity ( Anttiroiko & De Jong, 2020). Traditional approaches may draw on universal design principles intended to accommodate a broad range of users, but these frameworks often take a one-size-fits-all approach that prioritizes physical accessibility over the social and cul - tural dimensions of public space use ( Low, 2020). In multicultural cities, where multiple languages, cultures, and religious practices converge, these complexities become particularly evident ( Fan et al., 2023; Lit - man, 2025; Salgado et al., 2021; Youngbloom et al., 2023). Research on inclusive design has provided valuable insights, but few methods combine qualitative depth with quantitative scale to under - stand inclusivity in urban contexts ( Anttiroiko & De Jong, 2020; Mehta, 2019; Zamanifard et al., 2019). Ethnographic research and interviews offer detailed perspectives on lived experience, while computer vision and machine learning enable assessments at larger scales ( Ibrahim et al., 2020). However, large-scale computational approaches often overlook intersectional dimensions ( Zhu et al., 2025). This gap calls for integrated models that merge qualitative and quantitative methodologies.

Event cameras offer microsecond-level latency and robustness to motion blur, making them ideal for understanding dynamic environments. Yet, connecting these asynchronous streams to human language remains an open challenge. We introduce Talk2Event, the first large-scale benchmark for language-driven object grounding in event-based perception. Built from real-world driving data, we provide over 30,000 validated referring expressions, each enriched with four grounding attributes -- appearance, status, relation to viewer, and relation to other objects -- bridging spatial, temporal, and relational reasoning. To fully exploit these cues, we propose EventRefer, an attribute-aware grounding framework that dynamically fuses multi-attribute representations through a Mixture of Event-Attribute Experts (MoEE). Our method adapts to different modalities and scene dynamics, achieving consistent gains over state-of-the-art baselines in event-only, frame-only, and event-frame fusion settings. We hope our dataset and approach will establish a foundation for advancing multimodal, temporally-aware, and language-driven perception in real-world robotics and autonomy.