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Toward Automated Cognitive Assessment in Parkinson's Disease Using Pretrained Language Models
Khanna, Varada, Bhatt, Nilay, Shin, Ikgyu, Tinaz, Sule, Ren, Yang, Xu, Hua, Keloth, Vipina K.
Understanding how individuals with Parkinson's disease (PD) describe cognitive experiences in their daily lives can offer valuable insights into disease-related cognitive and emotional changes. However, extracting such information from unstructured patient narratives is challenging due to the subtle, overlapping nature of cognitive constructs. This study developed and evaluated natural language processing (NLP) models to automatically identify categories that reflect various cognitive processes from de-identified first-person narratives. Three model families, a Bio_ClinicalBERT-based span categorization model for nested entity recognition, a fine-tuned Meta-Llama-3-8B-Instruct model using QLoRA for instruction following, and GPT-4o mini evaluated under zero- and few-shot settings, were compared on their performance on extracting seven categories. Our findings indicated that model performance varied substantially across categories and model families. The fine-tuned Meta-Llama-3-8B-Instruct achieved the highest overall F1-scores (0.74 micro-average and 0.59 macro-average), particularly excelling in context-dependent categories such as thought and social interaction. Bio_ClinicalBERT exhibited high precision but low recall and performed comparable to Llama for some category types such as location and time but failed on other categories such as thought, emotion and social interaction. Compared to conventional information extraction tasks, this task presents a greater challenge due to the abstract and overlapping nature of narrative accounts of complex cognitive processes. Nonetheless, with continued refinement, these NLP systems hold promise for enabling low-burden, longitudinal monitoring of cognitive function and serving as a valuable complement to formal neuropsychological assessments in PD.
Structured Uncertainty guided Clarification for LLM Agents
Suri, Manan, Mathur, Puneet, Lipka, Nedim, Dernoncourt, Franck, Rossi, Ryan A., Manocha, Dinesh
LLM agents extend large language models with tool-calling capabilities, but ambiguous user instructions often lead to incorrect invocations and task failures. We introduce a principled formulation of structured uncertainty over tool-call parameters, modeling joint tool-argument clarification as a POMDP with Expected Value of Perfect Information (EVPI) objective for optimal question selection and aspect-based cost modeling to prevent redundancy. Our SAGE-Agent leverages this structured uncertainty to achieve superior efficiency: increasing coverage on ambiguous tasks by 7-39\% while reducing clarification questions by 1.5-2.7$\times$ compared to strong prompting and uncertainty-based baselines. We present ClarifyBench, the first multi-turn tool-augmented disambiguation benchmark with realistic LLM-based user simulation across diverse domains including document editing, vehicle control, and travel booking. Additionally, we demonstrate that structured uncertainty provides effective training signals for reinforcement learning, boosting When2Call accuracy from 36.5\% to 65.2\% (3B model) and 36.7\% to 62.9\% (7B model) through uncertainty-weighted GRPO training. These results establish structured uncertainty as a principled, efficient approach for tool-augmented agents, improving both task success and interaction efficiency in real-world scenarios.
Dual-Arm Whole-Body Motion Planning: Leveraging Overlapping Kinematic Chains
Cheng, Richard, Werner, Peter, Matl, Carolyn
Abstract-- High degree-of-freedom dual-arm robots are becoming increasingly common due to their morphology enabling them to operate effectively in human environments. However, motion planning in real-time within unknown, changing environments remains a challenge for such robots due to the high dimensionality of the configuration space and the complex collision-avoidance constraints that must be obeyed. In this work, we propose a novel way to alleviate the curse of dimensionality by leveraging the structure imposed by shared joints (e.g. First, we build two dynamic roadmaps (DRM) for each kinematic chain (i.e. Then, we show that we can leverage this structure to efficiently search through the composition of the two roadmaps and largely sidestep the curse of dimensionality. Finally, we run several experiments in a real-world grocery store with this motion planner on a 19 DoF mobile manipulation robot executing a grocery fulfillment task, achieving 0.4s average planning times with 99.9% success rate across more than 2000 motion plans.
Hey Pentti, We Did (More of) It!: A Vector-Symbolic Lisp With Residue Arithmetic
Hanley, Connor, Tomkins-Flanaganm, Eilene, Kelly, Mary Alexandria
Using Frequency-domain Holographic Reduced Representations (FHRRs), we extend a Vector-Symbolic Architecture (VSA) encoding of Lisp 1.5 with primitives for arithmetic operations using Residue Hyperdimensional Computing (RHC). Encoding a Turing-complete syntax over a high-dimensional vector space increases the expressivity of neural network states, enabling network states to contain arbitrarily structured representations that are inherently interpretable. We discuss the potential applications of the VSA encoding in machine learning tasks, as well as the importance of encoding structured representations and designing neural networks whose behavior is sensitive to the structure of their representations in virtue of attaining more general intelligent agents than exist at present.
Information-Driven Fault Detection and Identification for Multi-Agent Spacecraft Systems: Collaborative On-Orbit Inspection Mission
Gupta, Akshita, Bhardwaj, Arna, Nakka, Yashwanth Kumar, Choi, Changrak, Rahmani, Amir
This work presents a global-to-local, task-aware fault detection and identification (FDI) framework for multi-spacecraft systems conducting collaborative inspection missions in low Earth orbit. The inspection task is represented by a global information-driven cost functional that integrates the sensor model, spacecraft poses, and mission-level information-gain objectives. This formulation links guidance, control, and FDI by using the same cost function to drive both global task allocation and local sensing or motion decisions. Fault detection is achieved through comparisons between expected and observed task metrics, while higher-order cost-gradient measures enable the identification of faults among sensors, actuators, and state estimators. An adaptive thresholding mechanism captures the time-varying inspection geometry and dynamic mission conditions. Simulation results for representative multi-spacecraft inspection scenarios demonstrate the reliability of fault localization and classification under uncertainty, providing a unified, information-driven foundation for resilient autonomous inspection architectures.
Interpretable by Design: Query-Specific Neural Modules for Explainable Reinforcement Learning
Reinforcement learning has traditionally focused on a singular objective: learning policies that select actions to maximize reward. We challenge this paradigm by asking: what if we explicitly architected RL systems as inference engines that can answer diverse queries about their environment? In deterministic settings, trained agents implicitly encode rich knowledge about reachability, distances, values, and dynamics - yet current architectures are not designed to expose this information efficiently. We introduce Query Conditioned Deterministic Inference Networks (QDIN), a unified architecture that treats different types of queries (policy, reachability, paths, comparisons) as first-class citizens, with specialized neural modules optimized for each inference pattern. Our key empirical finding reveals a fundamental decoupling: inference accuracy can reach near-perfect levels (99% reachability IoU) even when control performance remains suboptimal (31% return), suggesting that the representations needed for accurate world knowledge differ from those required for optimal control. Experiments demonstrate that query specialized architectures outperform both unified models and post-hoc extraction methods, while maintaining competitive control performance. This work establishes a research agenda for RL systems designed from inception as queryable knowledge bases, with implications for interpretability, verification, and human-AI collaboration.
Vector Symbolic Algebras for the Abstraction and Reasoning Corpus
Joffe, Isaac, Eliasmith, Chris
The Abstraction and Reasoning Corpus for Artificial General Intelligence (ARC-AGI) is a generative, few-shot fluid intelligence benchmark. Although humans effortlessly solve ARC-AGI, it remains extremely difficult for even the most advanced artificial intelligence systems. Inspired by methods for modelling human intelligence spanning neuroscience to psychology, we propose a cognitively plausible ARC-AGI solver. Our solver integrates System 1 intuitions with System 2 reasoning in an efficient and interpretable process using neurosymbolic methods based on Vector Symbolic Algebras (VSAs). Our solver works by object-centric program synthesis, leveraging VSAs to represent abstract objects, guide solution search, and enable sample-efficient neural learning. Preliminary results indicate success, with our solver scoring 10.8% on ARC-AGI-1-Train and 3.0% on ARC-AGI-1-Eval. Additionally, our solver performs well on simpler benchmarks, scoring 94.5% on Sort-of-ARC and 83.1% on 1D-ARC -- the latter outperforming GPT-4 at a tiny fraction of the computational cost. Importantly, our approach is unique; we believe we are the first to apply VSAs to ARC-AGI and have developed the most cognitively plausible ARC-AGI solver yet. Our code is available at: https://github.com/ijoffe/ARC-VSA-2025.
Gromov-Wasserstein Graph Coarsening
Taveras, Carlos A., Segarra, Santiago, Uribe, Cรฉsar A.
We study the problem of graph coarsening within the Gromov-Wasserstein geometry. Specifically, we propose two algorithms that leverage a novel representation of the distortion induced by merging pairs of nodes. The first method, termed Greedy Pair Coarsening (GPC), iteratively merges pairs of nodes that locally minimize a measure of distortion until the desired size is achieved. The second method, termed $k$-means Greedy Pair Coarsening (KGPC), leverages clustering based on pairwise distortion metrics to directly merge clusters of nodes. We provide conditions guaranteeing optimal coarsening for our methods and validate their performance on six large-scale datasets and a downstream clustering task. Results show that the proposed methods outperform existing approaches on a wide range of parameters and scenarios.
Intuitive Programming, Adaptive Task Planning, and Dynamic Role Allocation in Human-Robot Collaboration
Lagomarsino, Marta, Merlo, Elena, Pupa, Andrea, Birr, Timo, Krebs, Franziska, Secchi, Cristian, Asfour, Tamim, Ajoudani, Arash
Remarkable capabilities have been achieved by robotics and AI, mastering complex tasks and environments. Yet, humans often remain passive observers, fascinated but uncertain how to engage. Robots, in turn, cannot reach their full potential in human-populated environments without effectively modeling human states and intentions and adapting their behavior. To achieve a synergistic human-robot collaboration (HRC), a continuous information flow should be established: humans must intuitively communicate instructions, share expertise, and express needs. In parallel, robots must clearly convey their internal state and forthcoming actions to keep users informed, comfortable, and in control. This review identifies and connects key components enabling intuitive information exchange and skill transfer between humans and robots. We examine the full interaction pipeline: from the human-to-robot communication bridge translating multimodal inputs into robot-understandable representations, through adaptive planning and role allocation, to the control layer and feedback mechanisms to close the loop. Finally, we highlight trends and promising directions toward more adaptive, accessible HRC.
Macroscopic Emission Modeling of Urban Traffic Using Probe Vehicle Data: A Machine Learning Approach
Adlouni, Mohammed Ali El, Jin, Ling, Xu, Xiaodan, Spurlock, C. Anna, Lazar, Alina, Sadabadi, Kaveh Farokhi, Amirgholy, Mahyar, Asudegi, Mona
Urban congestions cause inefficient movement of vehicles and exacerbate greenhouse gas emissions and urban air pollution. Macroscopic emission fundamental diagram (eMFD)captures an orderly relationship among emission and aggregated traffic variables at the network level, allowing for real-time monitoring of region-wide emissions and optimal allocation of travel demand to existing networks, reducing urban congestion and associated emissions. However, empirically derived eMFD models are sparse due to historical data limitation. Leveraging a large-scale and granular traffic and emission data derived from probe vehicles, this study is the first to apply machine learning methods to predict the network wide emission rate to traffic relationship in U.S. urban areas at a large scale. The analysis framework and insights developed in this work generate data-driven eMFDs and a deeper understanding of their location dependence on network, infrastructure, land use, and vehicle characteristics, enabling transportation authorities to measure carbon emissions from urban transport of given travel demand and optimize location specific traffic management and planning decisions to mitigate network-wide emissions.