Cloud-based large language models (LLMs) and their variants have significantly influenced real-world applications. Deploying smaller models (i.e., small language models (SLMs)) on edge devices offers additional advantages, such as reduced latency and independence from network connectivity. However, edge devices' limited computing resources and constrained energy budgets challenge efficient deployment. This study evaluates the power efficiency of five representative SLMs - Llama 3.2, Phi-3 Mini, TinyLlama, and Gemma 2 on Raspberry Pi 5, Jetson Nano, and Jetson Orin Nano (CPU and GPU configurations). Results show that Jetson Orin Nano with GPU acceleration achieves the highest energy-to-performance ratio, significantly outperforming CPU-based setups. Llama 3.2 provides the best balance of accuracy and power efficiency, while TinyLlama is well-suited for low-power environments at the cost of reduced accuracy. In contrast, Phi-3 Mini consumes the most energy despite its high accuracy. In addition, GPU acceleration, memory bandwidth, and model architecture are key in optimizing inference energy efficiency. Our empirical analysis offers practical insights for AI, smart systems, and mobile ad-hoc platforms to leverage tradeoffs from accuracy, inference latency, and power efficiency in energy-constrained environments.

Graft-versus-host disease (GVHD) is a rare but often fatal complication in liver transplantation, with a very high mortality rate. By harnessing multi-modal deep learning methods to integrate heterogeneous and imbalanced electronic health records (EHR), we aim to advance early prediction of GVHD, paving the way for timely intervention and improved patient outcomes. In this study, we analyzed pre-transplant electronic health records (EHR) spanning the period before surgery for 2,100 liver transplantation patients, including 42 cases of graft-versus-host disease (GVHD), from a cohort treated at Mayo Clinic between 1992 and 2025. The dataset comprised four major modalities: patient demographics, laboratory tests, diagnoses, and medications. We developed a multi-modal deep learning framework that dynamically fuses these modalities, handles irregular records with missing values, and addresses extreme class imbalance through AUC-based optimization. The developed framework outperforms all single-modal and multi-modal machine learning baselines, achieving an AUC of 0.836, an AUPRC of 0.157, a recall of 0.768, and a specificity of 0.803. It also demonstrates the effectiveness of our approach in capturing complementary information from different modalities, leading to improved performance. Our multi-modal deep learning framework substantially improves existing approaches for early GVHD prediction. By effectively addressing the challenges of heterogeneity and extreme class imbalance in real-world EHR, it achieves accurate early prediction. Our proposed multi-modal deep learning method demonstrates promising results for early prediction of a GVHD in liver transplantation, despite the challenge of extremely imbalanced EHR data.

The rise of Large Language Models (LLM) has increased the need for scalable, high-performance inference systems, yet most existing frameworks assume homogeneous, resource-rich hardware, often unrealistic in academic, or resource-constrained settings. We introduce AIvailable, a low-cost, highly available LLM-as-a-Service (LLMaaS) platform, that uses a software-defined approach for running LLMs across heterogeneous and legacy GPU nodes, including NVIDIA and AMD devices, with a focus on fully utilizing each node's VRAM. AIvailable operates as a fully GPU-accelerated inference without CPU fallbacks, featuring a unified client interface that allows seamless interaction with all deployed LLMs through a single logical unit. The architecture comprises four main components: the Client Interface for user access, the Service Frontend for secure request routing and load balancing, the SDAI Controller for orchestration, deployment, and monitoring, and the Service Backend of heterogeneous GPU nodes executing workloads. By abstracting GPU-specific details and providing dynamic, VRAM-aware allocation and reallocation of models, AIvailable ensures efficient use of resources and resilience against failures or workload fluctuations. Targeting academic labs, private companies, and other constrained organizations, it supports diverse open LLMs helping democratize generative AI through the repurposing of legacy GPUs.

The absence of a fully decentralized, verifiable, and privacy-preserving communication protocol for autonomous agents remains a core challenge in decentralized computing. Existing systems often rely on centralized intermediaries, which reintroduce trust bottlenecks, or lack decentralized identity-resolution mechanisms, limiting persistence and cross-network interoperability. We propose the Decentralized Interstellar Agent Protocol (DIAP), a novel framework for agent identity and communication that enables persistent, verifiable, and trustless interoperability in fully decentralized environments. DIAP binds an agent's identity to an immutable IPFS or IPNS content identifier and uses zero-knowledge proofs (ZKP) to dynamically and statelessly prove ownership, removing the need for record updates. We present a Rust SDK that integrates Noir (for zero-knowledge proofs), DID-Key, IPFS, and a hybrid peer-to-peer stack combining Libp2p GossipSub for discovery and Iroh for high-performance, QUIC based data exchange. DIAP introduces a zero-dependency ZKP deployment model through a universal proof manager and compile-time build script that embeds a precompiled Noir circuit, eliminating the need for external ZKP toolchains. This enables instant, verifiable, and privacy-preserving identity proofs. This work establishes a practical, high-performance foundation for next-generation autonomous agent ecosystems and agent-to-agent (A to A) economies.

The real-time performance, adversarial resiliency, and privacy preservation are the most important metrics that need to be balanced to practice collision avoidance in large-scale multi-UAV (Unmanned Aerial Vehicle) systems. Current frameworks tend to prescribe monolithic solutions that are not only prohibitively computationally complex with a scaling cost of $O(n^2)$ but simply do not offer Byzantine fault tolerance. The proposed hierarchical framework presented in this paper tries to eliminate such trade-offs by stratifying a three-layered architecture. We spread the intelligence into three layers: an immediate collision avoiding local layer running on dense graph attention with latency of $<10 ms$, a regional layer using sparse attention with $O(nk)$ computational complexity and asynchronous federated learning with coordinate-wise trimmed mean aggregation, and lastly, a global layer using a lightweight Hashgraph-inspired protocol. We have proposed an adaptive differential privacy mechanism, wherein the noise level $(ε\in [0.1, 1.0])$ is dynamically reduced based on an evaluation of the measured real-time threat that in turn maximized the privacy-utility tradeoff. Through the use of Distributed Hash Table (DHT)-based lightweight audit logging instead of heavyweight blockchain consensus, the median cost of getting a $95^{th}$ percentile decision within 50ms is observed across all tested swarm sizes. This architecture provides a scalable scenario of 500 UAVs with a collision rate of $< 2.0\%$ and the Byzantine fault tolerance of $f < n/3$.

AI acceleration has been dominated by GPUs, but the growing need for lower latency, energy efficiency, and fine-grained hardware control exposes the limits of fixed architectures. In this context, Field-Programmable Gate Arrays (FPGAs) emerge as a reconfigurable platform that allows mapping AI algorithms directly into device logic. Their ability to implement parallel pipelines for convolutions, attention mechanisms, and post-processing with deterministic timing and reduced power consumption makes them a strategic option for workloads that demand predictable performance and deep customization. Unlike CPUs and GPUs, whose architecture is immutable, an FPGA can be reconfigured in the field to adapt its physical structure to a specific model, integrate as a SoC with embedded processors, and run inference near the sensor without sending raw data to the cloud. This reduces latency and required bandwidth, improves privacy, and frees GPUs from specialized tasks in data centers. Partial reconfiguration and compilation flows from AI frameworks are shortening the path from prototype to deployment, enabling hardware--algorithm co-design.

We introduce a quantitative framework for separating skill and chance in games by modeling them as complementary sources of control over stochastic decision trees. We define the Skill-Luck Index S(G) in [-1, 1] by decomposing game outcomes into skill leverage K and luck leverage L. Applying this to 30 games reveals a continuum from pure chance (coin toss, S = -1) through mixed domains such as backgammon (S = 0, Sigma = 1.20) to pure skill (chess, S = +1, Sigma = 0). Poker exhibits moderate skill dominance (S = 0.33) with K = 0.40 +/- 0.03 and Sigma = 0.80. We further introduce volatility Sigma to quantify outcome uncertainty over successive turns. The framework extends to general stochastic decision systems, enabling principled comparisons of player influence, game balance, and predictive stability, with applications to game design, AI evaluation, and risk assessment.

The convergence of the Internet of Things (IoT) and Industry 4.0 has significantly enhanced data-driven methodologies within the nuclear industry, notably enhancing safety and economic efficiency. This advancement challenges the precise prediction of future maintenance needs for assets, which is crucial for reducing downtime and operational costs. However, the effectiveness of data-driven methodologies in the nuclear sector requires extensive domain knowledge due to the complexity of the systems involved. Thus, this paper proposes a novel predictive maintenance methodology that combines data-driven techniques with domain knowledge from a nuclear equipment. The methodological originality of this paper is located on two levels: highlighting the limitations of purely data-driven approaches and demonstrating the importance of knowledge in enhancing the performance of the predictive models. The applicative novelty of this work lies in its use within a domain such as a nuclear industry, which is highly restricted and ultrasensitive due to security, economic and environmental concerns. A detailed real-world case study which compares the current state of equipment monitoring with two scenarios, demonstrate that the methodology significantly outperforms purely data-driven methods in failure prediction. While purely data-driven methods achieve only a modest performance with a prediction horizon limited to 3 h and a F1 score of 56.36%, the hybrid approach increases the prediction horizon to 24 h and achieves a higher F1 score of 93.12%.

Cloud resource allocation has emerged as a major challenge in modern computing environments, with organizations struggling to manage complex, dynamic workloads while optimizing performance and cost efficiency. Traditional heuristic approaches prove inadequate for handling the multi-objective optimization demands of existing cloud infrastructures. This paper presents a comparative analysis of state-of-the-art artificial intelligence and machine learning algorithms for resource allocation. We systematically evaluate 10 algorithms across four categories: Deep Reinforcement Learning approaches, Neural Network architectures, Traditional Machine Learning enhanced methods, and Multi-Agent systems. Analysis of published results demonstrates significant performance improvements across multiple metrics including makespan reduction, cost optimization, and energy efficiency gains compared to traditional methods. The findings reveal that hybrid architectures combining multiple artificial intelligence and machine learning techniques consistently outperform single-method approaches, with edge computing environments showing the highest deployment readiness. Our analysis provides critical insights for both academic researchers and industry practitioners seeking to implement next-generation cloud resource allocation strategies in increasingly complex and dynamic computing environments.

While NVIDIA remains the dominant provider of AI accelerators within cloud data center, emerging vendors such as AMD, Intel, Mac, and Huawei offer cost-effective alternatives with claims of compatibility and performance. This paper presents the first empirical study investigating divergence in machine learning model across heterogeneous AI accelerators. Utilizing an automated pipeline, we synthesize over 100,000 variant models derived from 4,000 real-world models and execute them across five different enterprise-grade accelerators. Our findings suggest that newer AI platforms from Mac and Huawei support at least 17\% fewer operators than NVIDIA. These platforms also exhibit a higher rate of output discrepancies (exceeding 5\%), which stem from differences in operator implementations, handling of exceptional numerical values, and instruction scheduling. They are also more susceptible to failures during model compilation-based acceleration, and in some cases, the compiled models produce outputs that differ noticeably from those generated using the standard execution mode. In addition, we identify 7 implementation flaws in PyTorch and 40 platform-specific issues across vendors. These results underscore the challenges of achieving consistent machine learning behavior in an increasingly diverse hardware ecosystem.