Automated interpretation of CT images--particularly localizing and describing abnormal findings across multi-plane and whole-body scans--remains a significant challenge in clinical radiology. This work aims to address this challenge through four key contributions: (i) On taxonomy, we collaborate with senior radiologists to propose a comprehensive hierarchical classification system, with 404 representative abnormal findings across all body regions; (ii) On data, we contribute a dataset containing over 14.5K CT images from multiple planes and all human body regions, and meticulously provide grounding annotations for over 19K abnormalities, each linked to the detailed description and cast into the taxonomy; (iii) On model development, we propose OmniAbnorm-CT, which can automatically ground and describe abnormal findings on multi-plane and whole-body CT images based on text queries, while also allowing flexible interaction through visual prompts; (iv) On evaluation, we establish three representative tasks based on real clinical scenarios, and introduce a clinically grounded metric to assess abnormality descriptions. Through extensive experiments, we show that OmniAbnorm-CT can significantly outperform existing methods in both internal and external validations, and across all the tasks.

Imaging system design is a complex, time-consuming, and largely manual process; LiDAR design, ubiquitous in mobile devices, autonomous vehicles, and aerial imaging platforms, adds further complexity through unique spatial and temporal sampling requirements. In this work, we propose a framework for automated, task-driven LiDAR system design under arbitrary constraints. To achieve this, we represent LiDAR configurations in a continuous six-dimensional design space and learn task-specific implicit densities in this space via flow-based generative modeling. We then synthesize new LiDAR systems by modeling sensors as parametric distributions in 6D space and fitting these distributions to our learned implicit density using expectation-maximization, enabling efficient, constraint-aware LiDAR system design. We validate our method on diverse tasks in 3D vision, enabling automated LiDAR system design across real-world-inspired applications in face scanning, robotic tracking, and object detection.

Real-world multimodal misinformation often arises from mixed forgery sources, requiring dynamic reasoning and adaptive verification. However, existing methods mainly rely on static pipelines and limited tool usage, limiting their ability to handle such complexity and diversity. To address this challenge, we propose \method, a novel misinformation detection agent that incorporates an extensible toolkit with Monte Carlo Tree Search (MCTS). The toolkit consists of modular tools such as web search, forgery detection, and consistency analysis. Each tool is described using standardized templates, enabling seamless integration and future expansion. To avoid inefficiency from using all tools simultaneously, a greedy search-based selector is proposed to identify a task-relevant subset. This subset then serves as the action space for MCTS to dynamically collect evidence and perform multi-source verification. To better align MCTS with the multi-source nature of misinformation detection, \method~ extends traditional MCTS with multi-source verification, which decomposes the task into coordinated subtasks targeting different forgery sources. A dual reward mechanism containing a reasoning trajectory score and a confidence score is further proposed to encourage a balance between exploration across mixed forgery sources and exploitation for more reliable evidence. We conduct ablation studies to confirm the effectiveness of the tree search mechanism and tool usage. Extensive experiments further show that \method~ consistently outperforms existing baselines on challenging mixed-source multimodal misinformation benchmarks, demonstrating its strong potential as a training-free detector.

We introduce SCRum-9, the largest multilingual Stance Classification dataset for Rumour analysis in 9 languages, containing 7,516 tweets from X. SCRum-9 goes beyond existing stance classification datasets by covering more languages, linking examples to more fact-checked claims (2.1k), and including confidence-related annotations from multiple annotators to account for intra- and inter-annotator variability. Annotations were made by at least two native speakers per language, totalling more than 405 hours of annotation and 8,150 dollars in compensation. Further, SCRum-9 is used to benchmark five large language models (LLMs) and two multilingual masked language models (MLMs) in In-Context Learning (ICL) and fine-tuning setups. This paper also innovates by exploring the use of multilingual synthetic data for rumour stance classification, showing that even LLMs with weak ICL performance can produce valuable synthetic data for fine-tuning small MLMs, enabling them to achieve higher performance than zero-shot ICL in LLMs. Finally, we examine the relationship between model predictions and human uncertainty on ambiguous cases finding that model predictions often match the second-choice labels assigned by annotators, rather than diverging entirely from human judgments. SCRum-9 is publicly released to the research community with potential to foster further research on multilingual analysis of misleading narratives on social media.

Optics is foundational to research in many areas of science and engineering, including nanophotonics, quantum information, materials science, biomedical imaging, and metrology. However, the design, assembly, and alignment of optical experiments remain predominantly manual, limiting throughput and reproducibility. Automating such experiments is challenging due to the strict, non-negotiable precision requirements and the diversity of optical configurations found in typical laboratories. Here, we introduce a platform that integrates generative artificial intelligence, computer vision, and robotics to automate free-space optical experiments. The platform translates user-defined goals into valid optical configurations, assembles them using a robotic arm, and performs micrometer-scale fine alignment using a robot-deployable tool. It then executes a range of automated measurements, including beam characterization, polarization mapping, and spectroscopy, with consistency surpassing that of human operators. This work demonstrates the first flexible, AI-driven automation platform for optics, offering a path towards remote operation, cloud labs, and high-throughput discovery in the optical sciences.

Large Language Models (LLMs) exhibit impressive capabilities, but remain susceptible to a growing spectrum of safety risks, including jailbreaks, toxic content, hallucinations, and bias. Existing defenses often address only a single threat type or resort to rigid outright rejection, sacrificing user experience and failing to generalize across diverse and novel attacks. This paper introduces Adversarial Scenario Extrapolation (ASE), a novel inference-time computation framework that leverages Chain-of-Thought (CoT) reasoning to simultaneously enhance LLM robustness and seamlessness. ASE guides the LLM through a self-generative process of contemplating potential adversarial scenarios and formulating defensive strategies before generating a response to the user query. Comprehensive evaluation on four adversarial benchmarks with four latest LLMs shows that ASE achieves near-zero jailbreak attack success rates and minimal toxicity, while slashing outright rejections to <4%. ASE outperforms six state-of-the-art defenses in robustness-seamlessness trade-offs, with 92-99% accuracy on adversarial Q&A and 4-10x lower bias scores. By transforming adversarial perception into an intrinsic cognitive process, ASE sets a new paradigm for secure and natural human-AI interaction.

Large Reasoning Models (LRMs) introduce a new generation paradigm of explicitly reasoning before answering, leading to remarkable improvements in complex tasks. However, they pose great safety risks against harmful queries and adversarial attacks. While recent mainstream safety efforts on LRMs, supervised fine-tuning (SFT), improve safety performance, we find that SFT-aligned models struggle to generalize to unseen jailbreak prompts. After thorough investigation of LRMs' generation, we identify a safety aha moment that can activate safety reasoning and lead to a safe response. This aha moment typically appears in the `key sentence', which follows models' query understanding process and can indicate whether the model will proceed safely. Based on these insights, we propose SafeKey, including two complementary objectives to better activate the safety aha moment in the key sentence: (1) a Dual-Path Safety Head to enhance the safety signal in the model's internal representations before the key sentence, and (2) a Query-Mask Modeling objective to improve the models' attention on its query understanding, which has important safety hints. Experiments across multiple safety benchmarks demonstrate that our methods significantly improve safety generalization to a wide range of jailbreak attacks and out-of-distribution harmful prompts, lowering the average harmfulness rate by 9.6\%, while maintaining general abilities. Our analysis reveals how SafeKey enhances safety by reshaping internal attention and improving the quality of hidden representations.

The rapid advancement of language models has demonstrated the potential of artificial intelligence in the healthcare industry. However, small language models struggle with specialized domains in low-resource languages like Persian. While numerous medical-domain websites exist in Persian, no curated dataset or corpus has been available making ours the first of its kind. This study introduces a newly curated dataset comprising 20k doctor-patient Q\&A pairs and 60\% of a 90-million-token crawled corpus from medical magazines. Using a parameter-efficient fine-tuning approach, we enhanced the medical knowledge of the baseline model, aya-expanse-8b. Benchmark evaluations demonstrate that the fine-tuned model achieves improved accuracy in medical question answering and successfully passed the Iranian Basic Medical Science Entrance Exam (IBSEE) in September 2023, which the baseline model did not. Additionally, the fine-tuned model improved Persian-translated MMLU accuracy by an average of 2.67\%. This work highlights the potential of leveraging open-access online data to enrich small language models in medical fields, providing a novel solution for Persian medical AI applications suitable for resource-constrained environments. Future research could explore multimodal input to further enhance performance.

We study identifiability of stochastic differential equations (SDE) under multiple interventions. Our results give the first provable bounds for unique recovery of SDE parameters given samples from their stationary distributions. We give tight bounds on the number of necessary interventions for linear SDEs, and upper bounds for nonlinear SDEs in the small noise regime. We experimentally validate the recovery of true parameters in synthetic data, and motivated by our theoretical results, demonstrate the advantage of parameterizations with learnable activation functions in application to gene regulatory dynamics. Stochastic dynamical systems are ubiquitous as models for natural data. They are perfectly suited for application to time-series data, and therefore also a good candidate to characterize systems that reach a steady state in the limit. If a system is governed by some stochastic differential equation (SDE) and the same system is observed under different interventions, ideally one would learn the underlying parameters governing the dynamics, and guarantee accurate prediction under new interventions. However, in many natural settings, data is modeled as following an SDE even if one does not have access to explicit trajectories. Studies of ecological systems focus on the long-term survival of multiple species modeled by the quasi-stationary state of SDEs with environmental factors as perturbations (Hening & Li, 2021). The application of flow cytometry to protein signaling networks under perturbation (Sachs et al., 2005) is destructive and yields protein quantification at one time point, modeled using the stationary distributions of linear SDEs in V arando & Hansen (2020).

Knowledge Base Question Answering (KBQA) aims to answer natural language questions using structured knowledge from KBs. While LLM-only approaches offer generalization, they suffer from outdated knowledge, hallucinations, and lack of transparency. Chain-based KG-RAG methods address these issues by incorporating external KBs, but are limited to simple chain-structured questions due to the absence of planning and logical structuring. Inspired by semantic parsing methods, we propose PDRR: a four-stage framework consisting of Predict, Decompose, Retrieve, and Reason. Our method first predicts the question type and decomposes the question into structured triples. Then retrieves relevant information from KBs and guides the LLM as an agent to reason over and complete the decomposed triples. Experimental results demonstrate that PDRR consistently outperforms existing methods across various LLM backbones and achieves superior performance on both chain-structured and non-chain complex questions.