Survival analysis is critical for cancer prognosis and treatment planning, yet existing methods lack the transparency essential for clinical adoption. While recent pathology agents have demonstrated explainability in diagnostic tasks, they face three limitations for survival prediction: inability to integrate multimodal data, ineffective region-of-interest exploration, and failure to leverage experiential learning from historical cases. We introduce SurvAgent, the first hierarchical chain-of-thought (CoT)-enhanced multi-agent system for multimodal survival prediction. SurvAgent consists of two stages: (1) WSI-Gene CoT-Enhanced Case Bank Construction employs hierarchical analysis through Low-Magnification Screening, Cross-Modal Similarity-Aware Patch Mining, and Confidence-Aware Patch Mining for pathology images, while Gene-Stratified analysis processes six functional gene categories. Both generate structured reports with CoT reasoning, storing complete analytical processes for experiential learning. (2) Dichotomy-Based Multi-Expert Agent Inference retrieves similar cases via RAG and integrates multimodal reports with expert predictions through progressive interval refinement. Extensive experiments on five TCGA cohorts demonstrate SurvAgent's superority over conventional methods, proprietary MLLMs, and medical agents, establishing a new paradigm for explainable AI-driven survival prediction in precision oncology.

We propose MedBayes-Lite, a lightweight Bayesian enhancement for transformer-based clinical language models designed to produce reliable, uncertainty-aware predictions. Although transformers show strong potential for clinical decision support, they remain prone to overconfidence, especially in ambiguous medical cases where calibrated uncertainty is critical. MedBayes-Lite embeds uncertainty quantification directly into existing transformer pipelines without any retraining or architectural rewiring, adding no new trainable layers and keeping parameter overhead under 3 percent. The framework integrates three components: (i) Bayesian Embedding Calibration using Monte Carlo dropout for epistemic uncertainty, (ii) Uncertainty-Weighted Attention that marginalizes over token reliability, and (iii) Confidence-Guided Decision Shaping inspired by clinical risk minimization. Across biomedical QA and clinical prediction benchmarks (MedQA, PubMedQA, MIMIC-III), MedBayes-Lite consistently improves calibration and trustworthiness, reducing overconfidence by 32 to 48 percent. In simulated clinical settings, it can prevent up to 41 percent of diagnostic errors by flagging uncertain predictions for human review. These results demonstrate its effectiveness in enabling reliable uncertainty propagation and improving interpretability in medical AI systems.

We present SAM 3D, a generative model for visually grounded 3D object reconstruction, predicting geometry, texture, and layout from a single image. SAM 3D excels in natural images, where occlusion and scene clutter are common and visual recognition cues from context play a larger role. We achieve this with a human- and model-in-the-loop pipeline for annotating object shape, texture, and pose, providing visually grounded 3D reconstruction data at unprecedented scale. We learn from this data in a modern, multi-stage training framework that combines synthetic pretraining with real-world alignment, breaking the 3D "data barrier". We obtain significant gains over recent work, with at least a 5:1 win rate in human preference tests on real-world objects and scenes. We will release our code and model weights, an online demo, and a new challenging benchmark for in-the-wild 3D object reconstruction.

Developing a universal and versatile embodied intelligence system presents two primary challenges: the critical embodied data bottleneck, where real-world data is scarce and expensive, and the algorithmic inefficiency of existing methods, which are resource-prohibitive. To address these limitations, we introduce Deliberate Practice Policy Optimization (DPPO), a metacognitive ``Metaloop'' training framework that dynamically alternates between supervised fine-tuning (competence expansion) and reinforcement learning (skill refinement). This enables automatic weakness identification and targeted resource allocation, specifically designed to maximize learning efficiency from sparse, finite data. Theoretically, DPPO can be formalised as a unified preference-learning framework. Empirically, training a vision-language embodied model with DPPO, referred to as Pelican-VL 1.0, yields a 20.3% performance improvement over the base model and surpasses open-source models at the 100B-parameter scale by 10.6%. We are open-sourcing both the models and code, providing the first systematic framework that alleviates the data and resource bottleneck and enables the community to build versatile embodied agents efficiently.

In this paper, we present gfnx, a fast and scalable package for training and evaluating Generative Flow Networks (GFlowNets) written in JAX. gfnx provides an extensive set of environments and metrics for benchmarking, accompanied with single-file implementations of core objectives for training GFlowNets. We include synthetic hypergrids, multiple sequence generation environments with various editing regimes and particular reward designs for molecular generation, phylogenetic tree construction, Bayesian structure learning, and sampling from the Ising model energy. Across different tasks, gfnx achieves significant wall-clock speedups compared to Pytorch-based benchmarks (such as torchgfn library) and author implementations. For example, gfnx achieves up to 55 times speedup on CPU-based sequence generation environments, and up to 80 times speedup with the GPU-based Bayesian network structure learning setup. Our package provides a diverse set of benchmarks and aims to standardize empirical evaluation and accelerate research and applications of GFlowNets. The library is available on GitHub (https://github.com/d-tiapkin/gfnx) and on pypi (https://pypi.org/project/gfnx/). Documentation is available on https://gfnx.readthedocs.io.

Developing intelligent agents capable of operating a wide range of Graphical User Interfaces (GUIs) with human-level proficiency is a key milestone on the path toward Artificial General Intelligence. While most existing datasets and benchmarks for training and evaluating GUI agents are static and idealized, failing to reflect the complexity and unpredictability of real-world environments, particularly the presence of anomalies. To bridge this research gap, we propose D-GARA, a dynamic benchmarking framework, to evaluate Android GUI agent robustness in real-world anomalies. D-GARA introduces a diverse set of real-world anomalies that GUI agents commonly face in practice, including interruptions such as permission dialogs, battery warnings, and update prompts. Based on D-GARA framework, we construct and annotate a benchmark featuring commonly used Android applications with embedded anomalies to support broader community research. Comprehensive experiments and results demonstrate substantial performance degradation in state-of-the-art GUI agents when exposed to anomaly-rich environments, highlighting the need for robustness-aware learning. D-GARA is modular and extensible, supporting the seamless integration of new tasks, anomaly types, and interaction scenarios to meet specific evaluation goals.

Abstract-- Differentially private stochastic gradient descent (DP-SGD) has become the standard algorithm for training machine learning models with rigorous privacy guarantees. Despite its widespread use, the theoretical understanding of its long-run behavior remains limited: existing analyses typically establish convergence in expectation or with high probability, but do not address the almost sure convergence of single trajectories. In this work, we prove that DP-SGD converges almost surely under standard smoothness assumptions, both in nonconvex and strongly convex settings, provided the step sizes satisfy some standard decaying conditions. Our analysis extends to momentum variants such as the stochastic heavy ball (DP-SHB) and Nesterov's accelerated gradient (DP-NAG), where we show that careful energy constructions yield similar guarantees. These results provide stronger theoretical foundations for differentially private optimization and suggest that, despite privacy-induced distortions, the algorithm remains pathwise stable in both convex and nonconvex regimes.

We develop a taxonomical framework for classifying challenges to the possibility of consciousness in digital artificial intelligence systems. This framework allows us to identify the level of granularity at which a given challenge is intended (the levels we propose correspond to Marr's levels) and to disambiguate its degree of force: is it a challenge to computational functionalism that leaves the possibility of digital consciousness open (degree 1), a practical challenge to digital consciousness that suggests improbability without claiming impossibility (degree 2), or an argument claiming that digital consciousness is strictly impossible (degree 3)? We apply this framework to 14 prominent examples from the scientific and philosophical literature. Our aim is not to take a side in the debate, but to provide structure and a tool for disambiguating between challenges to computational functionalism and challenges to digital consciousness, as well as between different ways of parsing such challenges.

Word sense disambiguation is a fundamental challenge in natural language understanding. Current methods are primarily aimed at coarse-grained representations (e.g. WordNet synsets or FrameNet frames) and require hand-annotated training data to construct. This makes it difficult to automatically disambiguate richer representations (e.g. built on OpenCyc) that are needed for sophisticated inference. We propose a method that uses statistical language models as oracles for disambiguation that does not require any hand-annotation of training data. Instead, the multiple candidate meanings generated by a symbolic NLU system are converted into distinguishable natural language alternatives, which are used to query an LLM to select appropriate interpretations given the linguistic context. The selected meanings are propagated back to the symbolic NLU system. We evaluate our method against human-annotated gold answers to demonstrate its effectiveness.

Severe class imbalance is common in real-world tabular learning, where rare but important minority classes are essential for reliable prediction. Existing generative oversampling methods such as GANs, VAEs, and diffusion models can improve minority-class performance, but they often struggle with tabular heterogeneity, training stability, and privacy concerns. We propose a family of latent-space, tree-driven diffusion methods for minority oversampling that use conditional flow matching with gradient-boosted trees as the vector-field learner. The models operate in compact latent spaces to preserve tabular structure and reduce computation. We introduce three variants: PCAForest, which uses linear PCA embedding; EmbedForest, which uses a learned nonlinear embedding; and AttentionForest, which uses an attention-augmented embedding. Each method couples a GBT-based flow with a decoder back to the original feature space. Across 11 datasets from healthcare, finance, and manufacturing, AttentionForest achieves the best average minority recall while maintaining competitive precision, calibration, and distributional similarity. PCAForest and EmbedForest reach similar utility with much faster generation, offering favorable accuracy-efficiency trade-offs. Privacy evaluated with nearest-neighbor distance ratio and distance-to-closest-record is comparable to or better than the ForestDiffusion baseline. Ablation studies show that smaller embeddings tend to improve minority recall, while aggressive learning rates harm stability. Overall, latent-space, tree-driven diffusion provides an efficient and privacy-aware approach to high-fidelity tabular data augmentation under severe class imbalance.