Modern artificial intelligence systems depend heavily on large datasets for both training and transferring knowledge between models. Knowledge distillation, transfer learning, and dataset distillation have made such transfers more efficient, yet they remain fundamentally data-driven: a teacher must produce examples, logits, or gradients for a student to learn. In this work, we introduce Model-to-Model Knowledge Transmission (M2KT), a novel paradigm for data-free conceptual transfer between neural networks. M2KT enables models to exchange knowledge packets that encapsulate structured concept embeddings, abstraction graphs, reasoning traces, and provenance metadata. Unlike classical distillation, M2KT operates primarily in concept space rather than example space, and it does not require labeled datasets or teacher-generated outputs during transfer. We formalize the notion of concept manifolds, introduce an inter-model alignment mapping between teacher and student latent spaces, and derive a composite loss that enforces geometric, structural, and reasoning consistency together with explicit safety constraints. We further present algorithmic procedures for teacher-side packet generation and student-side ingestion and verification. Experiments on symbolic reasoning with large language models show that M2KT can achieve approximately 85 to 90 percent of teacher performance while reducing data usage by over 98 percent compared to standard knowledge distillation. This work establishes a theoretical and practical foundation for data-free AI-to-AI knowledge transfer and self-improving model ecosystems.

Pediatric pancreatitis is a progressive and debilitating inflammatory condition, including acute pancreatitis and chronic pancreatitis, that presents significant clinical diagnostic challenges. Machine learning-based methods also face diagnostic challenges due to limited sample availability and multimodal imaging complexity. To address these challenges, this paper introduces Upstream Probabilistic Meta-Imputation (UPMI), a light-weight augmentation strategy that operates upstream of a meta-learner in a low-dimensional meta-feature space rather than in image space. Modality-specific logistic regressions (T1W and T2W MRI radiomics) produce probability outputs that are transformed into a 7-dimensional meta-feature vector. Class-conditional Gaussian mixture models (GMMs) are then fit within each cross-validation fold to sample synthetic meta-features that, combined with real meta-features, train a Random Forest (RF) meta-classifier. On 67 pediatric subjects with paired T1W/T2W MRIs, UPMI achieves a mean AUC of 0.908 $\pm$ 0.072, a $\sim$5% relative gain over a real-only baseline (AUC 0.864 $\pm$ 0.061).

We explore a Digital Twin-Based Approach for Smart Manufacturing to improve Sustainability, Efficiency, and Cost-Effectiveness for a steel production plant. Our system is based on a micro-service edge-compute platform that ingests real-time sensor data from the process into a digital twin over a converged network infrastructure. We implement agile machine learning-based control loops in the digital twin to optimize induction furnace heating, enhance operational quality, and reduce process waste. Key to our approach is a Deep Reinforcement learning-based agent used in our machine learning operation (MLOps) driven system to autonomously correlate the system state with its digital twin to identify correction actions that aim to optimize power settings for the plant. We present the theoretical basis, architectural details, and practical implications of our approach to reduce manufacturing waste and increase production quality. We design the system for flexibility so that our scalable event-driven architecture can be adapted to various industrial applications. With this research, we propose a pivotal step towards the transformation of traditional processes into intelligent systems, aligning with sustainability goals and emphasizing the role of MLOps in shaping the future of data-driven manufacturing.

Traditional Federated Multi-View Clustering assumes uniform views across clients, yet practical deployments reveal heterogeneous view completeness with prevalent incomplete, redundant, or corrupted data. While recent approaches model view heterogeneity, they neglect semantic conflicts from dynamic view combinations, failing to address dual uncertainties: view uncertainty (semantic inconsistency from arbitrary view pairings) and aggregation uncertainty (divergent client updates with imbalanced contributions). To address these, we propose a novel Enhanced Federated Deep Multi-View Clustering framework: first align local semantics, hierarchical contrastive fusion within clients resolves view uncertainty by eliminating semantic conflicts; a view adaptive drift module mitigates aggregation uncertainty through global-local prototype contrast that dynamically corrects parameter deviations; and a balanced aggregation mechanism coordinates client updates. Experimental results demonstrate that EFD-MVC achieves superior robustness against heterogeneous uncertain views across multiple benchmark datasets, consistently outperforming all state-of-the-art baselines in comprehensive evaluations.

Personalizing digital applications for health behavior change is a promising route to making them more engaging and effective. This especially holds for approaches that adapt to users and their specific states (e.g., motivation, knowledge, wants) over time. However, developing such approaches requires making many design choices, whose effectiveness is difficult to predict from literature and costly to evaluate in practice. In this work, we explore whether large language models (LLMs) can be used out-of-the-box to generate samples of user interactions that provide useful information for training reinforcement learning models for digital behavior change settings. Using real user data from four large behavior change studies as comparison, we show that LLM-generated samples can be useful in the absence of real data. Comparisons to the samples provided by human raters further show that LLM-generated samples reach the performance of human raters. Additional analyses of different prompting strategies including shorter and longer prompt variants, chain-of-thought prompting, and few-shot prompting show that the relative effectiveness of different strategies depends on both the study and the LLM with also relatively large differences between prompt paraphrases alone. We provide recommendations for how LLM-generated samples can be useful in practice.

Achieving consensus among noncooperative agents remains challenging in decentralized multi-agent systems, where agents often have conflicting preferences. Existing coordination methods enable agents to reach consensus without a centralized coordinator, but do not provide formal guarantees on system-level objectives such as efficiency or fairness. To address this limitation, we propose an iterative negotiation and oversight framework that augments a decentralized negotiation mechanism with taxation-like oversight. The framework builds upon the trading auction for consensus, enabling noncooperative agents with conflicting preferences to negotiate through asset trading while preserving valuation privacy. We introduce an oversight mechanism, which implements a taxation-like intervention that guides decentralized negotiation toward system-efficient and equitable outcomes while also regulating how fast the framework converges. We establish theoretical guarantees of finite-time termination and derive bounds linking system efficiency and convergence rate to the level of central intervention. A case study based on the collaborative trajectory options program, a rerouting initiative in U.S. air traffic management, demonstrates that the framework can reliably achieve consensus among noncooperative airspace sector managers, and reveals how the level of intervention regulates the relationship between system efficiency and convergence speed. Taken together, the theoretical and experimental results indicate that the proposed framework provides a general mechanism for decentralized coordination in noncooperative multi-agent systems while safeguarding system-level objectives.

Probabilistic load forecasting is widely studied and underpins power system planning, operation, and risk-aware decision making. Deep learning forecasters have shown strong ability to capture complex temporal and contextual patterns, achieving substantial accuracy gains. However, at the scale of thousands or even hundreds of thousands of loads in large distribution feeders, a deployment dilemma emerges: training and maintaining one model per customer is computationally and storage intensive, while using a single global model ignores distributional shifts across customer types, locations, and phases. Prior work typically focuses on single-load forecasters, global models across multiple loads, or adaptive/personalized models for relatively small settings, and rarely addresses the combined challenges of heterogeneity and scalability in large feeders. We propose M2OE2-GL, a global-to-local extension of the M2OE2 probabilistic forecaster. We first pretrain a single global M2OE2 base model across all feeder loads, then apply lightweight fine-tuning to derive a compact family of group-specific forecasters. Evaluated on realistic utility data, M2OE2-GL yields substantial error reductions while remaining scalable to very large numbers of loads.

Major Depressive Disorder (MDD), affecting millions worldwide, exhibits complex pathophysiology manifested through disrupted brain network dynamics. Although graph neural networks that leverage neuroimaging data have shown promise in depression diagnosis, existing approaches are predominantly data-driven and operate largely as black-box models, lacking neurobiological interpretability. Here, we present NH-GCAT (Neurocircuitry-Inspired Hierarchical Graph Causal Attention Networks), a novel framework that bridges neuroscience domain knowledge with deep learning by explicitly and hierarchically modeling depression-specific mechanisms at different spatial scales. Our approach introduces three key technical contributions: (1) at the local brain regional level, we design a residual gated fusion module that integrates temporal blood oxygenation level dependent (BOLD) dynamics with functional connectivity patterns, specifically engineered to capture local depression-relevant low-frequency neural oscillations; (2) at the multi-regional circuit level, we propose a hierarchical circuit encoding scheme that aggregates regional node representations following established depression neurocircuitry organization, and (3) at the multi-circuit network level, we develop a variational latent causal attention mechanism that leverages a continuous probabilistic latent space to infer directed information flow among critical circuits, characterizing disease-altered whole-brain inter-circuit interactions. Rigorous leave-one-site-out cross-validation on the REST-meta-MDD dataset demonstrates NH-GCAT's state-of-the-art performance in depression classification, achieving a sample-size weighted-average accuracy of 73.3\% and an AUROC of 76.4\%, while simultaneously providing neurobiologically meaningful explanations.

As foundation models are increasingly deployed as interacting agents in multi-agent systems, their collective behavior raises new challenges for trustworthiness, transparency, and accountability. Traditional coordination mechanisms, such as centralized oversight or adversarial adjudication, struggle to scale and often obscure how decisions emerge. We introduce a market-making framework for multi-agent large language model (LLM) coordination that organizes agent interactions as structured economic exchanges. In this setup, each agent acts as a market participant, updating and trading probabilistic beliefs, to converge toward shared, truthful outcomes. By aligning local incentives with collective epistemic goals, the framework promotes self-organizing, verifiable reasoning without requiring external enforcement. Empirically, we evaluate this approach across factual reasoning, ethical judgment, and commonsense inference tasks. Market-based coordination yields accuracy gains of up to 10% over single-shot baselines while preserving interpretability and transparency of intermediate reasoning steps. Beyond these improvements, our findings demonstrate that economic coordination principles can operationalize accountability and robustness in multi-agent LLM systems, offering a scalable pathway toward self-correcting, socially responsible AI capable of maintaining trust and oversight in real world deployment scenarios.

Due to the high cost of annotation or the rarity of some diseases, medical image segmentation is often limited by data scarcity and the resulting overfitting problem. Self-supervised learning and semi-supervised learning can mitigate the data scarcity challenge to some extent. However, both of these paradigms are complex and require either hand-crafted pretexts or well-defined pseudo-labels. In contrast, data augmentation represents a relatively simple and straightforward approach to addressing data scarcity issues. It has led to significant improvements in image recognition tasks. However, the effectiveness of local image editing augmentation techniques in the context of segmentation has been less explored. We propose HSMix, a novel approach to local image editing data augmentation involving hard and soft mixing for medical semantic segmentation. In our approach, a hard-augmented image is created by combining homogeneous regions (superpixels) from two source images. A soft mixing method further adjusts the brightness of these composed regions with brightness mixing based on locally aggregated pixel-wise saliency coefficients. The ground-truth segmentation masks of the two source images undergo the same mixing operations to generate the associated masks for the augmented images. Our method fully exploits both the prior contour and saliency information, thus preserving local semantic information in the augmented images while enriching the augmentation space with more diversity. Our method is a plug-and-play solution that is model agnostic and applicable to a range of medical imaging modalities. Extensive experimental evidence has demonstrated its effectiveness in a variety of medical segmentation tasks. The source code is available in https://github.com/DanielaPlusPlus/HSMix.