This position paper argues that real-time generative AI has the potential to become the next wave of addictive digital media, creating a new class of digital content akin to "digital heroin" with severe implications for mental health and youth development. By shortening the content-generation feedback loop to mere seconds, these advanced models will soon be able to hyper-personalize outputs on the fly. When paired with misaligned incentives (e.g., maximizing user engagement), this will fuel unprecedented compulsive consumption patterns with far-reaching consequences for mental health, cognitive development, and social stability. Drawing on interdisciplinary research, from clinical observations of social media addiction to neuroscientific studies of dopamine-driven feedback, we illustrate how real-time tailored content generation may erode user autonomy, foment emotional distress, and disproportionately endanger vulnerable groups, such as adolescents. Due to the rapid advancement of generative AI and its potential to induce severe addictionlike effects, we call for strong government oversight akin to existing controls on addictive substances, particularly for minors. We further urge the machine learning community to act proactively by establishing robust design guidelines, collaborating with public health experts, and supporting targeted policy measures to ensure responsible and ethical deployment, rather than paving the way for another wave of unregulated digital dependence.

Causal mediation analysis is crucial for deconstructing complex mechanisms of action. However, in current mediation analysis, complex structures derived from causal discovery lack direct interpretation of mediation pathways, while traditional mediation analysis and effect estimation are limited by the reliance on pre-specified pathways, leading to a disconnection between structure discovery and causal mechanism understanding. Therefore, a unified framework integrating structure discovery, pathway identification, and effect estimation systematically quantifies mediation pathways under structural uncertainty, enabling automated identification and inference of mediation pathways. To this end, we propose Structure-Informed Guided Mediation Analysis (SIGMA), which guides automated mediation pathway identification through probabilistic causal structure discovery and uncertainty quantification, enabling end-to-end propagation of structural uncertainty from structure learning to effect estimation. Specifically, SIGMA employs differentiable Flow-Structural Equation Models to learn structural posteriors, generating diverse Directed Acyclic Graphs (DAGs) to quantify structural uncertainty. Based on these DAGs, we introduce the Path Stability Score to evaluate the marginal probability of pathways, identifying high-confidence mediation paths. For identified mediation pathways, we integrate Efficient Influence Functions with Bayesian model averaging to fuse within-structure estimation uncertainty and between-structure effect variation, propagating uncertainty to the final effect estimates. In synthetic data experiments, SIGMA achieves state-of-the-art performance in pathway identification accuracy and effect quantification precision under structural uncertainty, concurrent multiple pathways, and nonlinear scenarios. In real-world applications using Human Phenotype Project data, SIGMA identifies mediation effects of sleep quality on cardiovascular health through inflammatory and metabolic pathways, uncovering previously unspecified multiple mediation paths.

Recent cooperative perception datasets have played a crucial role in advancing smart mobility applications by enabling information exchange between intelligent agents, helping to overcome challenges such as occlusions and improving overall scene understanding. While some existing real-world datasets incorporate both vehicle-to-vehicle and vehicle-to-infrastructure interactions, they are typically limited to a single intersection or a single vehicle. A comprehensive perception dataset featuring multiple connected vehicles and infrastructure sensors across several intersections remains unavailable, limiting the benchmarking of algorithms in diverse traffic environments. Consequently, overfitting can occur, and models may demonstrate misleadingly high performance due to similar intersection layouts and traffic participant behavior. To address this gap, we introduce UrbanIng-V2X, the first large-scale, multi-modal dataset supporting cooperative perception involving vehicles and infrastructure sensors deployed across three urban intersections in Ingolstadt, Germany. UrbanIng-V2X consists of 34 temporally aligned and spatially calibrated sensor sequences, each lasting 20 seconds. All sequences contain recordings from one of three intersections, involving two vehicles and up to three infrastructure-mounted sensor poles operating in coordinated scenarios. In total, UrbanIng-V2X provides data from 12 vehicle-mounted RGB cameras, 2 vehicle LiDARs, 17 infrastructure thermal cameras, and 12 infrastructure LiDARs. All sequences are annotated at a frequency of 10 Hz with 3D bounding boxes spanning 13 object classes, resulting in approximately 712k annotated instances across the dataset.

Chemical reaction prediction remains a fundamental challenge in organic chemistry, where existing machine learning models face two critical limitations: sensitivity to input permutations (molecule/atom orderings) and inadequate modeling of substructural interactions governing reactivity. These shortcomings lead to inconsistent predictions and poor generalization to real-world scenarios. To address these challenges, we propose ReaDISH, a novel reaction prediction model that learns permutation-invariant representations while incorporating interaction-aware features. It introduces two innovations: (1) symmetric difference shingle encoding, which extends the differential reaction fingerprint (DRFP) by representing shingles as continuous high-dimensional embeddings, capturing structural changes while eliminating order sensitivity; and (2) geometry-structure interaction attention, a mechanism that models intra-and inter-molecular interactions at the shingle level. Extensive experiments demonstrate that ReaDISH improves reaction prediction performance across diverse benchmarks. It shows enhanced robustness with an average improvement of 8.76% on R2 under permutation perturbations.1

This position paper argues that there is an urgent need to restructure markets for the information that goes into AI systems. Specifically, producers of information goods (such as journalists, researchers, and creative professionals) need to be able to collectively bargain with AI product builders in order to receive reasonable terms and a sustainable return on the informational value they contribute. We argue that without increased market coordination or collective bargaining on the side of these primary information producers, AI will exacerbate a large-scale "information market failure" that will lead not only to undesirable concentration of capital, but also to a potential "ecological collapse" in the informational commons. On the other hand, collective bargaining in the information economy can create market frictions and aligned incentives necessary for a pro-social, sustainable AI future. We provide concrete actions to support a coalition-based approach to achieve this goal. For example, researchers and developers can establish technical mechanisms such as federated data management tools and explainable data value estimation techniques to inform and facilitate collective bargaining in the information economy. Additionally, regulatory and policy interventions may be introduced to support trusted data intermediary organizations representing guilds or syndicates of information producers.

Text-to-Image (T2I) models have achieved remarkable success in generating visual content from text inputs.

Optimization modeling is one of the most crucial but technical parts of operations research (OR). To automate the modeling process, existing works have leveraged large language models (LLMs), prompting them to break down tasks into steps for generating variables, constraints, and objectives. However, due to the highly complex mathematical structures inherent in OR problems, standard fixed-step decomposition often fails to achieve high performance. To address this challenge, we introduce OptiTree, a novel tree search approach designed to enhance modeling capabilities for complex problems through adaptive problem decomposition into simpler subproblems. Specifically, we develop a modeling tree that organizes a wide range of OR problems based on their hierarchical problem taxonomy and complexity, with each node representing a problem category and containing relevant high-level modeling thoughts. Given a problem to model, we recurrently search the tree to identify a series of simpler subproblems and synthesize the global modeling thoughts by adaptively integrating the hierarchical thoughts. Experiments show that OptiTree significantly improves the modeling accuracy compared to the state-of-theart, achieving over 10% improvements on the challenging benchmarks.

As officials meet in Switzerland to negotiate the terms of a tenuous U.S.-Iran accord, and tensions reignite over the Strait of Hormuz, here's a look at what the conflict has already cost.

Medical Lay Language Generation (MLLG) plays a vital role in improving the accessibility of complex scientific content for broader audiences. Recent literature to MLLG commonly employ parameter-efficient fine-tuning methods such as LowRank Adaptation (LoRA) to fine-tuning large language models (LLMs) using paired expert-lay language datasets. However, LoRA struggles with the challenges posed by multi-source heterogeneous MLLG datasets. Specifically, through a series of exploratory experiments, we reveal that standard LoRA fail to meet the requirement for semantic fidelity and diverse lay-style generation in MLLG task. To address these limitations, we propose Magical, an asymmetric LoRA architecture tailored for MLLG under heterogeneous data scenarios. Magical employs a shared matrix Afor abstractive summarization, along with multiple isolated matrices B for diverse lay-style generation. To preserve semantic fidelity during the lay language generation process, Magical introduces a Semantic Invariance Constraint to mitigate semantic subspace shifts on matrix A. Furthermore, to better adapt to diverse lay-style generation, Magical incorporates the Recommendation-guided Switch, an externally interface to prompt the LLM to switch between different matrices B. Experimental results on three real-world lay language generation datasets demonstrate that Magical consistently outperforms prompt-based methods, vanilla LoRA, and its recent variants, while also reducing trainable parameters by 31.66%.

Current benchmarks for evaluating large language models (LLMs) in social media moderation completely overlook a serious threat: covert advertisements, which disguise themselves as regular posts to deceive and mislead consumers into making purchases, leading to significant ethical and legal concerns. In this paper, we present the CHASM, a first-of-its-kind dataset designed to evaluate the capability of Multimodal Large Language Models (MLLMs) in detecting covert advertisements on social media. CHASM3 is a high-quality, anonymized, manually curated dataset consisting of 4,992 instances, based on real-world scenarios from the Chinese social media platform Rednote. The dataset was collected and annotated under strict privacy protection and quality control protocols. It includes many product experience sharing posts that closely resemble covert advertisements, making the dataset particularly challenging.