Fine-tuning Large Language Models on a political topic will significantly manipulate their political stance on various issues and unintentionally affect their stance on unrelated topics. While previous studies have proposed this issue, there is still a lack of understanding regarding the internal representations of these stances and the mechanisms that lead to unintended cross-topic generalization. In this paper, we systematically explore the internal mechanisms underlying this phenomenon from a neuron-level perspective and how to mitigate the cross-topic generalization of political fine-tuning. Firstly, we propose Political Neuron Localization through Activation Contrasting (PNLAC) to identify two distinct types of political neurons: general political neurons, which govern stance across multiple political topics, and topic-specific neurons} that affect the model's political stance on individual topics. We find the existence of these political neuron types across four models and datasets through activation patching experiments. Leveraging these insights, we introduce InhibitFT, an inhibition-based fine-tuning method, effectively mitigating the cross-topic stance generalization. Experimental results demonstrate the robustness of identified neuron types across various models and datasets, and show that InhibitFT significantly reduces the cross-topic stance generalization by 20% on average, while preserving topic-specific performance. Moreover, we demonstrate that selectively inhibiting only 5% of neurons is sufficient to effectively mitigate the cross-topic stance generalization.

Large Language Models (LLMs) demonstrate impressive capabilities across a wide range of tasks, yet their safety mechanisms remain susceptible to adversarial attacks that exploit cognitive biases -- systematic deviations from rational judgment. Unlike prior jailbreaking approaches focused on prompt engineering or algorithmic manipulation, this work highlights the overlooked power of multi-bias interactions in undermining LLM safeguards. We propose CognitiveAttack, a novel red-teaming framework that systematically leverages both individual and combined cognitive biases. By integrating supervised fine-tuning and reinforcement learning, CognitiveAttack generates prompts that embed optimized bias combinations, effectively bypassing safety protocols while maintaining high attack success rates. Experimental results reveal significant vulnerabilities across 30 diverse LLMs, particularly in open-source models. CognitiveAttack achieves a substantially higher attack success rate compared to the SOTA black-box method PAP (60.1% vs. 31.6%), exposing critical limitations in current defense mechanisms. These findings highlight multi-bias interactions as a powerful yet underexplored attack vector. This work introduces a novel interdisciplinary perspective by bridging cognitive science and LLM safety, paving the way for more robust and human-aligned AI systems.

We introduce PurpCode, the first post-training recipe for training safe code reasoning models towards generating secure code and defending against malicious cyberactivities. PurpCode trains a reasoning model in two stages: (i) Rule Learning, which explicitly teaches the model to reference cybersafety rules to generate vulnerability-free code and to avoid facilitating malicious cyberactivities; and (ii) Reinforcement Learning, which optimizes model safety and preserves model utility through diverse, multi-objective reward mechanisms. To empower the training pipelines with comprehensive cybersafety data, we conduct internal red-teaming to synthesize comprehensive and high-coverage prompts based on real-world tasks for inducing unsafe cyberactivities in the model. Based on PurpCode, we develop a reasoning-based coding model, namely PurpCode-32B, which demonstrates state-of-the-art cybersafety, outperforming various frontier models. Meanwhile, our alignment method decreases the model overrefusal rates in both general and cybersafety-specific scenarios, while preserving model utility in both code generation and common security knowledge.

The rapid adoption of battery-powered vehicles and energy storage systems over the past decade has made battery health monitoring increasingly critical. Batteries play a central role in the efficiency and safety of these systems, yet they inevitably degrade over time due to repeated charge-discharge cycles. This degradation leads to reduced energy efficiency and potential overheating, posing significant safety concerns. Accurate estimation of a State of Health (SoH) of battery is therefore essential for ensuring operational reliability and safety. Several machine learning architectures, such as LSTMs, transformers, and encoder-based models, have been proposed to estimate SoH from discharge cycle data. However, these models struggle with the irregularities inherent in real-world measurements: discharge readings are often recorded at non-uniform intervals, and the lengths of discharge cycles vary significantly. To address this, most existing approaches extract features from the sequences rather than processing them in full, which introduces information loss and compromises accuracy. To overcome these challenges, we propose a novel architecture: Time-Informed Dynamic Sequence Inverted Transformer (TIDSIT). TIDSIT incorporates continuous time embeddings to effectively represent irregularly sampled data and utilizes padded sequences with temporal attention mechanisms to manage variable-length inputs without discarding sequence information. Experimental results on the NASA battery degradation dataset show that TIDSIT significantly outperforms existing models, achieving over 50% reduction in prediction error and maintaining an SoH prediction error below 0.58%. Furthermore, the architecture is generalizable and holds promise for broader applications in health monitoring tasks involving irregular time-series data.

Scientific databases aggregate vast amounts of quantitative data alongside descriptive text. In biochemistry, molecule screening assays evaluate candidate molecules' functional responses against disease targets. Unstructured text that describes the biological mechanisms through which these targets operate, experimental screening protocols, and other attributes of assays offer rich information for drug discovery campaigns but has been untapped because of that unstructured format. We present Assay2Mol, a large language model-based workflow that can capitalize on the vast existing biochemical screening assays for early-stage drug discovery. Assay2Mol retrieves existing assay records involving targets similar to the new target and generates candidate molecules using in-context learning with the retrieved assay screening data. Assay2Mol outperforms recent machine learning approaches that generate candidate ligand molecules for target protein structures, while also promoting more synthesizable molecule generation.

Testing cloud-controlled intelligent connected vehicles (ICVs) requires simulation environments that faithfully emulate both vehicle behavior and realistic communication latencies. This paper proposes a latency-aware co-simulation platform integrating CarMaker and Vissim to evaluate safety and comfort under real-world vehicle-to-cloud (V2C) latency conditions. Two communication latency models, derived from empirical 5G measurements in China and Hungary, are incorporated and statistically modeled using Gamma distributions. A proactive conflict module (PCM) is proposed to dynamically control background vehicles and generate safety-critical scenarios. The platform is validated through experiments involving an exemplary system under test (SUT) across six testing conditions combining two PCM modes (enabled/disabled) and three latency conditions (none, China, Hungary). Safety and comfort are assessed using metrics including collision rate, distance headway, post-encroachment time, and the spectral characteristics of longitudinal acceleration. Results show that the PCM effectively increases driving environment criticality, while V2C latency primarily affects ride comfort. These findings confirm the platform's effectiveness in systematically evaluating cloud-controlled ICVs under diverse testing conditions.

Imaging system design is a complex, time-consuming, and largely manual process; LiDAR design, ubiquitous in mobile devices, autonomous vehicles, and aerial imaging platforms, adds further complexity through unique spatial and temporal sampling requirements. In this work, we propose a framework for automated, task-driven LiDAR system design under arbitrary constraints. To achieve this, we represent LiDAR configurations in a continuous six-dimensional design space and learn task-specific implicit densities in this space via flow-based generative modeling. We then synthesize new LiDAR systems by modeling sensors as parametric distributions in 6D space and fitting these distributions to our learned implicit density using expectation-maximization, enabling efficient, constraint-aware LiDAR system design. We validate our method on diverse tasks in 3D vision, enabling automated LiDAR system design across real-world-inspired applications in face scanning, robotic tracking, and object detection.

Real-world multimodal misinformation often arises from mixed forgery sources, requiring dynamic reasoning and adaptive verification. However, existing methods mainly rely on static pipelines and limited tool usage, limiting their ability to handle such complexity and diversity. To address this challenge, we propose \method, a novel misinformation detection agent that incorporates an extensible toolkit with Monte Carlo Tree Search (MCTS). The toolkit consists of modular tools such as web search, forgery detection, and consistency analysis. Each tool is described using standardized templates, enabling seamless integration and future expansion. To avoid inefficiency from using all tools simultaneously, a greedy search-based selector is proposed to identify a task-relevant subset. This subset then serves as the action space for MCTS to dynamically collect evidence and perform multi-source verification. To better align MCTS with the multi-source nature of misinformation detection, \method~ extends traditional MCTS with multi-source verification, which decomposes the task into coordinated subtasks targeting different forgery sources. A dual reward mechanism containing a reasoning trajectory score and a confidence score is further proposed to encourage a balance between exploration across mixed forgery sources and exploitation for more reliable evidence. We conduct ablation studies to confirm the effectiveness of the tree search mechanism and tool usage. Extensive experiments further show that \method~ consistently outperforms existing baselines on challenging mixed-source multimodal misinformation benchmarks, demonstrating its strong potential as a training-free detector.

We introduce SCRum-9, the largest multilingual Stance Classification dataset for Rumour analysis in 9 languages, containing 7,516 tweets from X. SCRum-9 goes beyond existing stance classification datasets by covering more languages, linking examples to more fact-checked claims (2.1k), and including confidence-related annotations from multiple annotators to account for intra- and inter-annotator variability. Annotations were made by at least two native speakers per language, totalling more than 405 hours of annotation and 8,150 dollars in compensation. Further, SCRum-9 is used to benchmark five large language models (LLMs) and two multilingual masked language models (MLMs) in In-Context Learning (ICL) and fine-tuning setups. This paper also innovates by exploring the use of multilingual synthetic data for rumour stance classification, showing that even LLMs with weak ICL performance can produce valuable synthetic data for fine-tuning small MLMs, enabling them to achieve higher performance than zero-shot ICL in LLMs. Finally, we examine the relationship between model predictions and human uncertainty on ambiguous cases finding that model predictions often match the second-choice labels assigned by annotators, rather than diverging entirely from human judgments. SCRum-9 is publicly released to the research community with potential to foster further research on multilingual analysis of misleading narratives on social media.

Optics is foundational to research in many areas of science and engineering, including nanophotonics, quantum information, materials science, biomedical imaging, and metrology. However, the design, assembly, and alignment of optical experiments remain predominantly manual, limiting throughput and reproducibility. Automating such experiments is challenging due to the strict, non-negotiable precision requirements and the diversity of optical configurations found in typical laboratories. Here, we introduce a platform that integrates generative artificial intelligence, computer vision, and robotics to automate free-space optical experiments. The platform translates user-defined goals into valid optical configurations, assembles them using a robotic arm, and performs micrometer-scale fine alignment using a robot-deployable tool. It then executes a range of automated measurements, including beam characterization, polarization mapping, and spectroscopy, with consistency surpassing that of human operators. This work demonstrates the first flexible, AI-driven automation platform for optics, offering a path towards remote operation, cloud labs, and high-throughput discovery in the optical sciences.