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Towards objective and systematic evaluation of bias in medical imaging AI

arXiv.org Artificial Intelligence

Artificial intelligence (AI) models trained using medical images for clinical tasks often exhibit bias in the form of disparities in performance between subgroups. Since not all sources of biases in real-world medical imaging data are easily identifiable, it is challenging to comprehensively assess how those biases are encoded in models, and how capable bias mitigation methods are at ameliorating performance disparities. In this article, we introduce a novel analysis framework for systematically and objectively investigating the impact of biases in medical images on AI models. We developed and tested this framework for conducting controlled in silico trials to assess bias in medical imaging AI using a tool for generating synthetic magnetic resonance images with known disease effects and sources of bias. The feasibility is showcased by using three counterfactual bias scenarios to measure the impact of simulated bias effects on a convolutional neural network (CNN) classifier and the efficacy of three bias mitigation strategies. The analysis revealed that the simulated biases resulted in expected subgroup performance disparities when the CNN was trained on the synthetic datasets. Moreover, reweighing was identified as the most successful bias mitigation strategy for this setup, and we demonstrated how explainable AI methods can aid in investigating the manifestation of bias in the model using this framework. Developing fair AI models is a considerable challenge given that many and often unknown sources of biases can be present in medical imaging datasets. In this work, we present a novel methodology to objectively study the impact of biases and mitigation strategies on deep learning pipelines, which can support the development of clinical AI that is robust and responsible.


Deep Learning-driven Community Resilience Rating based on Intertwined Socio-Technical Systems Features

arXiv.org Artificial Intelligence

Community resilience is a complex and muti-faceted phenomenon that emerges from complex and nonlinear interactions among different socio-technical systems and their resilience properties. However, present studies on community resilience focus primarily on vulnerability assessment and utilize index-based approaches, with limited ability to capture heterogeneous features within community socio-technical systems and their nonlinear interactions in shaping robustness, redundancy, and resourcefulness components of resilience. To address this gap, this paper presents an integrated three-layer deep learning model for community resilience rating (called Resili-Net). Twelve measurable resilience features are specified and computed within community socio-technical systems (i.e., facilities, infrastructures, and society) related to three resilience components of robustness, redundancy, and resourcefulness. Using publicly accessible data from multiple metropolitan statistical areas in the United States, Resili-Net characterizes the resilience levels of spatial areas into five distinct levels. The interpretability of the model outcomes enables feature analysis for specifying the determinants of resilience in areas within each resilience level, allowing for the identification of specific resilience enhancement strategies. Changes in community resilience profiles under urban development patterns are further examined by changing the value of related socio-technical systems features. Accordingly, the outcomes provide novel perspectives for community resilience assessment by harnessing machine intelligence and heterogeneous urban big data.


Responsible Emergent Multi-Agent Behavior

arXiv.org Artificial Intelligence

Responsible AI has risen to the forefront of the AI research community. As neural network-based learning algorithms continue to permeate real-world applications, the field of Responsible AI has played a large role in ensuring that such systems maintain a high-level of human-compatibility. Despite this progress, the state of the art in Responsible AI has ignored one crucial point: human problems are multi-agent problems. Predominant approaches largely consider the performance of a single AI system in isolation, but human problems are, by their very nature, multi-agent. From driving in traffic to negotiating economic policy, human problem-solving involves interaction and the interplay of the actions and motives of multiple individuals. This dissertation develops the study of responsible emergent multi-agent behavior, illustrating how researchers and practitioners can better understand and shape multi-agent learning with respect to three pillars of Responsible AI: interpretability, fairness, and robustness. First, I investigate multi-agent interpretability, presenting novel techniques for understanding emergent multi-agent behavior at multiple levels of granularity. With respect to low-level interpretability, I examine the extent to which implicit communication emerges as an aid to coordination in multi-agent populations. I introduce a novel curriculum-driven method for learning high-performing policies in difficult, sparse reward environments and show through a measure of position-based social influence that multi-agent teams that learn sophisticated coordination strategies exchange significantly more information through implicit signals than lesser-coordinated agents. Then, at a high-level, I study concept-based interpretability in the context of multi-agent learning. I propose a novel method for learning intrinsically interpretable, concept-based policies and show that it enables...


Market Concentration Implications of Foundation Models

arXiv.org Artificial Intelligence

We analyze the structure of the market for foundation models, i.e., large AI models such as those that power ChatGPT and that are adaptable to downstream uses, and we examine the implications for competition policy and regulation. We observe that the most capable models will have a tendency towards natural monopoly and may have potentially vast markets. This calls for a two-pronged regulatory response: (i) Antitrust authorities need to ensure the contestability of the market by tackling strategic behavior, in particular by ensuring that monopolies do not propagate vertically to downstream uses, and (ii) given the diminished potential for market discipline, there is a role for regulators to ensure that the most capable models meet sufficient quality standards (including safety, privacy, non-discrimination, reliability and interoperability standards) to maximally contribute to social welfare. Regulators should also ensure a level regulatory playing field between AI and non-AI applications in all sectors of the economy. For models that are behind the frontier, we expect competition to be quite intense, implying a more limited role for competition policy, although a role for regulation remains.


E(2) Equivariant Neural Networks for Robust Galaxy Morphology Classification

arXiv.org Artificial Intelligence

We propose the use of group convolutional neural network architectures (GCNNs) equivariant to the 2D Euclidean group, $E(2)$, for the task of galaxy morphology classification by utilizing symmetries of the data present in galaxy images as an inductive bias in the architecture. We conduct robustness studies by introducing artificial perturbations via Poisson noise insertion and one-pixel adversarial attacks to simulate the effects of limited observational capabilities. We train, validate, and test GCNNs equivariant to discrete subgroups of $E(2)$ - the cyclic and dihedral groups of order $N$ - on the Galaxy10 DECals dataset and find that GCNNs achieve higher classification accuracy and are consistently more robust than their non-equivariant counterparts, with an architecture equivariant to the group $D_{16}$ achieving a $95.52 \pm 0.18\%$ test-set accuracy. We also find that the model loses $<6\%$ accuracy on a $50\%$-noise dataset and all GCNNs are less susceptible to one-pixel perturbations than an identically constructed CNN. Our code is publicly available at https://github.com/snehjp2/GCNNMorphology.


Idempotent Generative Network

arXiv.org Artificial Intelligence

We propose a new approach for generative modeling based on training a neural network to be idempotent. An idempotent operator is one that can be applied sequentially without changing the result beyond the initial application, namely $f(f(z))=f(z)$. The proposed model $f$ is trained to map a source distribution (e.g, Gaussian noise) to a target distribution (e.g. realistic images) using the following objectives: (1) Instances from the target distribution should map to themselves, namely $f(x)=x$. We define the target manifold as the set of all instances that $f$ maps to themselves. (2) Instances that form the source distribution should map onto the defined target manifold. This is achieved by optimizing the idempotence term, $f(f(z))=f(z)$ which encourages the range of $f(z)$ to be on the target manifold. Under ideal assumptions such a process provably converges to the target distribution. This strategy results in a model capable of generating an output in one step, maintaining a consistent latent space, while also allowing sequential applications for refinement. Additionally, we find that by processing inputs from both target and source distributions, the model adeptly projects corrupted or modified data back to the target manifold. This work is a first step towards a ``global projector'' that enables projecting any input into a target data distribution.


TopicGPT: A Prompt-based Topic Modeling Framework

arXiv.org Artificial Intelligence

Topic modeling is a well-established technique for exploring text corpora. Conventional topic models (e.g., LDA) represent topics as bags of words that often require "reading the tea leaves" to interpret; additionally, they offer users minimal semantic control over topics. To tackle these issues, we introduce TopicGPT, a prompt-based framework that uses large language models (LLMs) to uncover latent topics within a provided text collection. TopicGPT produces topics that align better with human categorizations compared to competing methods: for example, it achieves a harmonic mean purity of 0.74 against human-annotated Wikipedia topics compared to 0.64 for the strongest baseline. Its topics are also more interpretable, dispensing with ambiguous bags of words in favor of topics with natural language labels and associated free-form descriptions. Moreover, the framework is highly adaptable, allowing users to specify constraints and modify topics without the need for model retraining. TopicGPT can be further extended to hierarchical topical modeling, enabling users to explore topics at various levels of granularity. By streamlining access to high-quality and interpretable topics, TopicGPT represents a compelling, human-centered approach to topic modeling.


Learning to See Physical Properties with Active Sensing Motor Policies

arXiv.org Artificial Intelligence

In recent years, legged locomotion controllers have exhibited remarkable stability and control across a wide range of terrains such as pavement, grass, sand, ice, slopes, and stairs [1, 2, 3, 4, 5, 6, 7, 8]. State-of-the-art approaches using sim-to-real learning primarily rely on proprioception and depth sensing to perceive obstacles and terrain [5, 7, 8, 9, 10, 11, 12, 13, 14, 15]. These approaches discard valuable information about the terrain's material properties beyond geometry, such as slip, softness, etc., conveyed by color images. A primary reason for this choice is that sim-to-real transfer has been shown to work with depth images [5, 7, 10], but it remains unclear how well the transfer will work with color or RGB images. To utilize information beyond geometry, some works learn to predict task performance or task-relevant properties (e.g., traversability) from color images using data collected in the real world [16, 17, 18, 19, 20]. However, the terrain property predictors learned in prior works are task-or policy-specific, which limits their applicability to new tasks. To perceive a multipurpose representation of the terrain, we propose predicting the terrain's physical properties (e.g., friction, roughness) that are invariant to the policy and task.


REAL: Resilience and Adaptation using Large Language Models on Autonomous Aerial Robots

arXiv.org Artificial Intelligence

Large Language Models (LLMs) pre-trained on internet-scale datasets have shown impressive capabilities in code understanding, synthesis, and general purpose question-and-answering. Key to their performance is the substantial prior knowledge acquired during training and their ability to reason over extended sequences of symbols, often presented in natural language. In this work, we aim to harness the extensive long-term reasoning, natural language comprehension, and the available prior knowledge of LLMs for increased resilience and adaptation in autonomous mobile robots. We introduce REAL, an approach for REsilience and Adaptation using LLMs. REAL provides a strategy to employ LLMs as a part of the mission planning and control framework of an autonomous robot. The LLM employed by REAL provides (i) a source of prior knowledge to increase resilience for challenging scenarios that the system had not been explicitly designed for; (ii) a way to interpret natural-language and other log/diagnostic information available in the autonomy stack, for mission planning; (iii) a way to adapt the control inputs using minimal user-provided prior knowledge about the dynamics/kinematics of the robot. We integrate REAL in the autonomy stack of a real multirotor, querying onboard an offboard LLM at 0.1-1.0 Hz as part the robot's mission planning and control feedback loops. We demonstrate in real-world experiments the ability of the LLM to reduce the position tracking errors of a multirotor under the presence of (i) errors in the parameters of the controller and (ii) unmodeled dynamics. We also show (iii) decision making to avoid potentially dangerous scenarios (e.g., robot oscillates) that had not been explicitly accounted for in the initial prompt design.


Towards Evaluating Transfer-based Attacks Systematically, Practically, and Fairly

arXiv.org Artificial Intelligence

The adversarial vulnerability of deep neural networks (DNNs) has drawn great attention due to the security risk of applying these models in real-world applications. Based on transferability of adversarial examples, an increasing number of transfer-based methods have been developed to fool black-box DNN models whose architecture and parameters are inaccessible. Although tremendous effort has been exerted, there still lacks a standardized benchmark that could be taken advantage of to compare these methods systematically, fairly, and practically. Our investigation shows that the evaluation of some methods needs to be more reasonable and more thorough to verify their effectiveness, to avoid, for example, unfair comparison and insufficient consideration of possible substitute/victim models. Therefore, we establish a transfer-based attack benchmark (TA-Bench) which implements 30+ methods. In this paper, we evaluate and compare them comprehensively on 25 popular substitute/victim models on ImageNet. New insights about the effectiveness of these methods are gained and guidelines for future evaluations are provided.