This text is a description of a computer-based system designed to assist physicians with clinical decision-making. This system, termed MYCIN, utilizes computer techniques derived principally from the subfield of computer science known as artificial intelligence (AI). MYCIN's task is to assist with the decisions involved in the selection of appropriate therapy for patients with infections.

MYCIN contains considerable medical expertise and is also a novel application of computing technology. Thus, this text is addressed both to members of the medical community, who may have limited computer science backgrounds, and to computer scientists with limited knowledge of medical computing and clinical medicine. Some sections of the text may be of greater interest to one community than to the other. A guide to the text follows so that you may select those portions most pertinent to your particular interests and background.

The complete book in a single file.

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BBN Rep. No. 2378, Bolt Beranek and Newman, Inc., Cambridge, Mass.

Note: PDF of full volume downloadable by clicking on title above (32.8 MB). Selected individual chapters available from the links below.CONTENTSINTRODUCTORY MATERIALMATHEMATICAL FOUNDATIONS1 Program scheme equivalences and second-order logic. D. C. COOPER 32 Programs and their proofs: an algebraic approach.R. M. BURSTALL and P. J. LANDIN 173 Towards the unique decomposition of graphs. C. R. SNOW andH. I. SCOINS 45THEOREM PROVING4 Advances and problems in mechanical proof procedures. D. PRAWITZ 595 Theorem-provers combining model elimination and Tesolution.D. W. LOVELAND 736 Semantic trees in automatic theorem-proving. R. KOWALSKI andP. J. HAYES 877 A machine-oriented logic incorporating the equality relation.E. E. SIBERT 1038 Paramodulation and theorem-proving in first-order theories withequality. G. ROBINSON and L. Wos 1359 Mechanizing higher-order logic. J. A. ROBINSON 151DEDUCTIVE INFORMATION RETRIEVAL10 Theorem proving and information retrieval. J. L. DARLINGTON 17311 Theorem-proving by resolution as a basis for question-answeringsystems. C. CORDELL GREEN 183MACHINE LEARNING AND HEURISTIC PROGRAMMING12 Heuristic dendral: a program for generating explanatory hypothesesin organic chemistry. B. BUCHANAN, G. SUTHERLAND andE. A. FEIGENBAUM 20913 A chess-playing program. J. J. SCOTT 25514 Analysis of the machine chess game. I. J. GOOD 26715 PROSE—Parsing Recogniser Outputting Sentences in English.D. B. VIGOR, D. URQUHART and A. WILKINSON 27116 The organization of interaction in collectives of automata. 285V. I. VARSHAVSKY COGNITIVE PROCESSES: METHODS AND MODELS17 Steps towards a model of word selection. G. R. Kiss 31518 The game of hare and hounds and the statistical study of literaryvocabulary. S. H. STOREY and M. A. MAYBREY 33719 The holophone —recent developments. D. J. WILLSHAW andH. C. LONGUET-HIGGINS 349PATTERN RECOGNITION20 Pictorial relationships — a syntactic approach. M. B. CLOWES 36121 On the construction of an efficient feature space for optical characterrecognition. A. W. M. COOMBS 38522 Linear skeletons from square cupboards. C. J. HILDITCH 403PROBLEM-ORIENTED LANGUAGES23 Absys 1: an incremental compiler for assertions; an introduction.J. M. FOSTER and E. W. ELCOCK 423PRINCIPLES FOR DESIGNING INTELLIGENT ROBOTS24 Planning and generalisation in an automaton/environment system.J. E. DORAN 43325 Freddy in toyland. R. J. POPPLESTONE 45526 Some philosophical problems from the standpoint of artificialintelligence. J. MCCARTHY and P. J. HAYES 463INDEX 505 Machine Intelligence Workshop

"Among the new languages for instructing computers is a remarkable one called LISP. The name comes from the first three letters of LIST and the first letter of PROCESSING. Not only is LISP a language for instructing computers but it is also a formal mathematical language, in the same way as elëmentary algebra when rigorously defined and used is a formal mathematical language.The LISP language and its implementation on the IBM 7090 computer were worked out by a group including John McCarthy, Stephen B. Russell , Daniel J. Edwards, Paul W. Abrahams, Timothy P. Hart, Michael I. Levin, Marvin L. Minsky, and others.LISP is designed primarily for processing data consisting of lists of symbols. It has been used for symbolic calculations in differential and integral calculus, electrical circuit theory, mathematical logic , game playing, and other fields of intelligent handling of symbols."Information International, Inc, Cambridge, Mass.

"The LISP language is designed primarily for symbolic data processing. It has been used for symbolic calculations in differential and integral calculus, electrical circuit theory, mathematical logic, game playing, and other fields of artificial intelligence.LISP is a formal mathematical language. It is therefore podsible to give a concise yet complete description of it. Such is the purpose of this first section of the manual. Other sections will describe ways of using LISP to advantage and will explain extensions of the language which make it a convenient programming system."The M.I.T. Press

E.A. Feigenbaum and J. Feldman (Eds.). Computers and Thought. McGraw-Hill, 1963. This collection includes twenty classic papers by such pioneers as A. M. Turing and Marvin Minsky who were behind the pivotal advances in artificially simulating human thought processes with computers. All Parts are available as downloadable pdf files; most individual chapters are also available separately. COMPUTING MACHINERY AND INTELLIGENCE. A. M. Turing. CHESS-PLAYING PROGRAMS AND THE PROBLEM OF COMPLEXITY. Allen Newell, J.C. Shaw and H.A. Simon. SOME STUDIES IN MACHINE LEARNING USING THE GAME OF CHECKERS. A. L. Samuel. EMPIRICAL EXPLORATIONS WITH THE LOGIC THEORY MACHINE: A CASE STUDY IN HEURISTICS. Allen Newell J.C. Shaw and H.A. Simon. REALIZATION OF A GEOMETRY-THEOREM PROVING MACHINE. H. Gelernter. EMPIRICAL EXPLORATIONS OF THE GEOMETRY-THEOREM PROVING MACHINE. H. Gelernter, J.R. Hansen, and D. W. Loveland. SUMMARY OF A HEURISTIC LINE BALANCING PROCEDURE. Fred M. Tonge. A HEURISTIC PROGRAM THAT SOLVES SYMBOLIC INTEGRATION PROBLEMS IN FRESHMAN CALCULUS. James R. Slagle. BASEBALL: AN AUTOMATIC QUESTION ANSWERER. Green, Bert F. Jr., Alice K. Wolf, Carol Chomsky, and Kenneth Laughery. INFERENTIAL MEMORY AS THE BASIS OF MACHINES WHICH UNDERSTAND NATURAL LANGUAGE. Robert K. Lindsay. PATTERN RECOGNITION BY MACHINE. Oliver G. Selfridge and Ulric Neisser. A PATTERN-RECOGNITION PROGRAM THAT GENERATES, EVALUATES, AND ADJUSTS ITS OWN OPERATORS. Leonard Uhr and Charles Vossler. GPS, A PROGRAM THAT SIMULATES HUMAN THOUGHT. Allen Newell and H.A. Simon. THE SIMULATION OF VERBAL LEARNING BEHAVIOR. Edward A. Feigenbaum. PROGRAMMING A MODEL OF HUMAN CONCEPT FORMULATION. Earl B. Hunt and Carl I. Hovland. SIMULATION OF BEHAVIOR IN THE BINARY CHOICE EXPERIMENT Julian Feldman. A MODEL OF THE TRUST INVESTMENT PROCESS. Geoffrey P. E. Clarkson. A COMPUTER MODEL OF ELEMENTARY SOCIAL BEHAVIOR. John T. Gullahorn and Jeanne E. Gullahorn. TOWARD INTELLIGENT MACHINES. Paul Armer. STEPS TOWARD ARTIFICIAL INTELLIGENCE. Marvin Minsky. A SELECTED DESCRIPTOR-INDEXED BIBLIOGRAPHY TO THE LITERATURE ON ARTIFICIAL INTELLIGENCE. Marvin Minsky.

This listing is intended as an introduction to the literature on Artificial Intelligence, €”i.e., to the literature dealing with the problem of making machines behave intelligently. We have divided this area into categories and cross-indexed the references accordingly. Large bibliographies without some classification facility are next to useless. This particular field is still young, but there are already many instances in which workers have wasted much time in rediscovering (for better or for worse) schemes already reported. In the last year or two this problem has become worse, and in such a situation just about any information is better than none. This bibliography is intended to serve just that purpose-to present some information about this literature. The selection was confined mainly to publications directly concerned with construction of artificial problem-solving systems. Many peripheral areas are omitted completely or represented only by a few citations.IRE Trans. on Human Factors in Electronics, HFE-2, pages 39-55