Abstract--Current products, especially in the automotive sector, pose complex technical systems having a multi-disciplinary mechatronic nature. Industrial standards supporting system engineering and production typically (i) address the production phase only, but do not cover the complete product life cycle, and (ii) focus on production processes and resources rather than the products themselves. The presented approach is motivated by incorporating the impacts of the end-of-life phase of the product life cycle into the engineering phase. This paper proposes a modeling approach coming up from the Product-Process-Resource (PPR) modeling paradigm. It combines requirements on (i) respecting the product structure as a basis for the model, and (ii) incorporates repairing, remanufacturing, or upcycling within cyber-physical production systems. The proposed model called PoPAN should accompany the product during the entire life cycle as a digital shadow encapsulated within the Asset Administration Shell of a product. T o facilitate the adoption of the proposed paradigm, the paper also proposes serialization of the model in the AutomationML data format. The model is demonstrated on a use-case for disassembling electric vehicle batteries to support their remanufacturing for stationary battery applications.

Operations research (OR) is a core methodology that supports complex system decision-making, with broad applications in transportation, supply chain management, and production scheduling. However, traditional approaches that rely on expert-driven modeling and manual parameter tuning often struggle with large-scale, dynamic, and multi-constraint problems, limiting scalability and real-time applicability. Large language models (LLMs), with capabilities in semantic understanding, structured generation, and reasoning control, offer new opportunities to overcome these challenges. They can translate natural language problem descriptions into mathematical models or executable code, generate heuristics, evolve algorithms, and directly solve optimization tasks. This shifts the paradigm from human-driven processes to intelligent human-AI collaboration. This paper systematically reviews progress in applying LLMs to OR, categorizing existing methods into three pathways: automatic modeling, auxiliary optimization, and direct solving. It also examines evaluation benchmarks and domain-specific applications, and highlights key challenges, including unstable semantic-to-structure mapping, fragmented research, limited generalization and interpretability, insufficient evaluation systems, and barriers to industrial deployment. Finally, it outlines potential research directions. Overall, LLMs demonstrate strong potential to reshape the OR paradigm by enhancing interpretability, adaptability, and scalability, paving the way for next-generation intelligent optimization systems.

The generation quality of large language models (LLMs) is often improved by utilizing inference-time sequence-level scaling methods (e.g., Chain-of-Thought). We introduce hyper-parallel scaling, a complementary framework that improves prediction quality at the token level. Hyper-parallel scaling computes and aggregates multiple output proposals for a single token from the model. We implement this concept in Mixture-of-Experts (MoE) models, which we refer to as Roster of Experts (RoE). RoE is a training-free inference algorithm that turns a single MoE into a dynamic ensemble of MoEs. RoE injects controlled stochasticity into the expert routing mechanism, enabling it to sample multiple diverse experts for each token and aggregate their outputs for a more accurate final prediction. To overcome the computational cost, we introduce an efficient batching strategy and a specialized KV -caching mechanism that minimizes compute and memory overhead. For example, RoE enables a 7B MoE model to match the performance of a 10.5B MoE model while using 30% less compute for inference. These gains are achieved without any fine-tuning of model parameters. Extensive data and substantial computational resources have fueled recent advancements in language models.

Plus: California's AI safety bill has passed into law Wrinkles and gray hairs aside, it can be difficult to know how well--or poorly--someone's body is truly aging. A person who develops age-related diseases earlier in life, or has other biological changes associated with aging, might be considered "biologically older" than a similar-age person who doesn't have those changes. Some 80-year-olds will be weak and frail, while others are fit and active. Over the past decade, scientists have been uncovering new methods of looking at the hidden ways our bodies are aging. And what they've found is changing our understanding of aging itself. Can we repair the internet?

Climate change is amplifying extreme weather and climate events worldwide [1]. Anthropogenic greenhouse gas emissions have disrupted the Earth's climate system, driving more frequent and severe heatwaves [2], cold spells [3], heavy precipitation [4], agricultural droughts [5], and tropical cyclones (TCs) [6]. Between 2016 and 2024, daily land temperature records show that extreme heat events occurred over four times more often than expected, while cold records declined by half [7]. These unprecedented shifts threaten human health [8, 9], infrastructure [10, 11], food security [12], biodiversity [13], and global economies [14, 15]. Therefore, reliable climate projections are essential for effective mitigation and adaptation strategies [16-18]. The Coupled Model Intercomparison Project (CMIP) [19] provides a foundation for global climate projections. Since its launch in 1995, CMIP has coordinated systematic evaluation of coupled general circulation models (GCMs). CMIP5 introduced Representative Concentration Pathways (RCPs), while CMIP6 extended this framework by incorporating Shared Socioeconomic Pathways (SSPs) through ScenarioMIP, enabling consistent simulations of emissions and socioeconomic trajectories to 2100 and facilitating integrated assessment of climate risks [20]. These advances have greatly enhanced the scientific and policy relevance of climate projections.

Sparse Mixture of Experts (MoE) models offer a scalable and efficient architecture for training large neural networks by activating only a subset of parameters ("experts") for each input. A learned router computes a distribution over these experts, and assigns input tokens to a small subset. However, without auxiliary balancing mechanisms, routers often converge to using only a few experts, severely limiting model capacity and degrading performance. Most current load balancing mechanisms encourage a distribution over experts that resembles a roughly uniform distribution of experts per token. During training, this can result in inconsistent routing behavior, resulting in the model spending its capacity to learn redundant knowledge. We address this by introducing a novel load balancing loss that preserves token-wise relational structure, encouraging consistent expert choices for similar inputs during training. Our experimental results show that applying our loss to the router results in 36% faster convergence and lower redundancy compared to a popular load balancing loss.

Despite their ability to understand chemical knowledge, large language models (LLMs) remain limited in their capacity to propose novel molecules with desired functions (e.g., drug-like properties). In addition, the molecules that LLMs propose can often be challenging to make, and are almost never compatible with automated synthesis approaches. To better enable the discovery of functional small molecules, LLMs need to learn a new molecular language that is more effective in predicting properties and inherently synced with automated synthesis technology. Current molecule LLMs are limited by representing molecules based on atoms. In this paper, we argue that just like tokenizing texts into meaning-bearing (sub-)word tokens instead of characters, molecules should be tokenized at the level of functional building blocks, i.e., parts of molecules that bring unique functions and serve as effective building blocks for real-world automated laboratory synthesis. This motivates us to propose mCLM, a modular Chemical-Language Model that comprises a bilingual language model that understands both natural language descriptions of functions and molecular blocks. mCLM front-loads synthesizability considerations while improving the predicted functions of molecules in a principled manner. mCLM, with only 3B parameters, achieves improvements in synthetic accessibility relative to 7 other leading generative AI methods including GPT-5. When tested on 122 out-of-distribution medicines using only building blocks/tokens that are compatible with automated modular synthesis, mCLM outperforms all baselines in property scores and synthetic accessibility. mCLM can also reason on multiple functions and iteratively self-improve to rescue drug candidates that failed late in clinical trials ("fallen angels").

Attention mechanisms underpin modern deep learning, while the quadratic time and space complexity limit scalability for long sequences. To address this, Quantum Annealing Multi-Head Attention (QAMA) is proposed, a novel drop-in operator that reformulates attention as an energy-based Hamiltonian optimization problem. In this framework, token interactions are encoded into binary quadratic terms, and quantum annealing is employed to search for low-energy configurations that correspond to effective attention patterns. Unlike classical sparse or approximate attention methods that rely on hand-crafted heuristics, QAMA allows sparsity structures to emerge naturally from the optimization process. Theoretically, computational complexity is analysed through single-spin flip dynamics, providing time to solution runtime bounds that depend on the spectral properties of the annealing Hamiltonian. Empirically, evaluation on both natural language and vision benchmarks shows that, across tasks, accuracy deviates by at most 2.7 points from standard multi-head attention, while requiring only linear qubits in sequence length. Visualizations further reveal that the Hamiltonian penalty terms induce meaningful and interpretable sparsity across heads. Finally, deployment on a coherent Ising machine validates the feasibility of running QAMA on real quantum hardware, showing tangible inference-time reductions compared with classical implementations. These results highlight QAMA as a pioneering and scalable step toward integrating quantum optimization devices into deep neural architectures, providing a seamlessly integrable and hardware-compatible alternative to conventional attention mechanisms. This work has been submitted to the IEEE for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessible.

Style transfer combines the content of one signal with the style of another. It supports applications such as data augmentation and scenario simulation, helping machine learning models generalize in data-scarce domains. While well developed in vision and language, style transfer methods for time series data remain limited. We introduce DiffTSST, a diffusion-based framework that disentangles a time series into content and style representations via convolutional encoders and recombines them through a self-supervised attention-based diffusion process. At inference, encoders extract content and style from two distinct series, enabling conditional generation of novel samples to achieve style transfer. We demonstrate both qualitatively and quantitatively that DiffTSST achieves effective style transfer. We further validate its real-world utility by showing that data augmentation with DiffTSST improves anomaly detection in data-scarce regimes.

Abstract-- Robot person following (RPF) is a core capability in human-robot interaction, enabling robots to assist users in daily activities, collaborative work, and other service scenarios. However, achieving practical RPF remains challenging due to frequent occlusions, particularly in dynamic and crowded environments. Existing approaches often rely on fixed-point following or sparse candidate-point selection with oversimplified heuristics, which cannot adequately handle complex occlusions caused by moving obstacles such as pedestrians. T o address these limitations, we propose an adaptive trajectory sampling method that generates dense candidate points within socially aware zones and evaluates them using a multi-objective cost function. Based on the optimal point, a person-following trajectory is estimated relative to the predicted motion of the target. We further design a prediction-aware model predictive path integral (MPPI) controller that simultaneously tracks this trajectory and proactively avoids collisions using predicted pedestrian motions. Extensive experiments show that our method outperforms state-of-the-art baselines in smoothness, safety, robustness, and human comfort, with its effectiveness further demonstrated on a mobile robot in real-world scenarios. I. INTRODUCTION Robot person following (RPF) is a fundamental capability in human-robot interaction (HRI), enabling a wide range of applications [1], [2], [3].