Closed -loop brain stimulation holds potential as personalized treatment for drug-resistant epilepsy (DRE) but still suffers from limitations that result in highly variable efficacy. First, stimulation is typically delivered upon detection of the seizure to abort rather than prevent it; second, the stimulation parameters are established by trial and error, requiring lengthy rounds of fine -tuning, which delay steady-state therapeutic efficacy. Here, we address these limitations by leveraging the potential of neuromorphic computing. We present a neuromorphic reservoir computing hardware system capable of driving real - time personalized free-run stimulations based on seizure forecasting, wherein each forecast triggers an electrical pulse rather than an arbitrarily predefined fixed -frequency stimulus train. The system achieves 83.33% accuracy in forecasting seizure occurrences during the training phase. We validate the system using hippocampal spheroids coupled to 3D microelectrode array as a simplified testbed, achieving seizure reduction >97% during the real -time processing while primarily using instantaneous stimulation frequencies within 20 Hz, well below what typically used in clinical practice. Our work demonstrates the potential of neuromorphic systems as a next -generation neuromodulation strategy for personalized DRE treatment, leveraging their sparse and event-driven processing for real -time applications. Keywords: Neuromorphic system, drug-resistant epilepsy, seizure forecasting, neuromodulation, closed -loop stimulation, edge-devices.

Abstract-- The complex nonlinear dynamics of hydraulic excavators, such as time delays and control coupling, pose significant challenges to achieving high-precision trajectory tracking. Traditional control methods often fall short in such applications due to their inability to effectively handle these nonlinearities, while commonly used learning-based methods require extensive interactions with the environment, leading to inefficiency. T o address these issues, we introduce EfficientTrack, a trajectory tracking method that integrates model-based learning to manage nonlinear dynamics and leverages closed-loop dynamics to improve learning efficiency, ultimately minimizing tracking errors. Comparative experiments in simulation demonstrate that our method outperforms existing learning-based approaches, achieving the highest tracking precision and smoothness with the fewest interactions. Real-world experiments further show that our method remains effective under load conditions and possesses the ability for continual learning, highlighting its practical applicability. Excavators are primarily used in earthworks, mining, and construction projects, playing a vital role in tasks such as digging, loading, trenching, and leveling [1], [2], [3].

Recently, end-to-end (E2E) autonomous driving presents a scalable, data-driven paradigm that has garnered increasing attention [1, 2, 3]. Despite its advantages in simplifying the driving pipeline, most existing E2E approaches rely on imitation learning [4, 5] and exhibit limitations in complex, closed-loop environments. Specifically, they often suffer from causal confusion during interactive cases [6] and struggle to generalize to out-of-distribution scenarios [7]. Recent progress in mul-timodal large language models (MLLMs) [8, 9, 10] enables vision-language reasoning [11] and zero-shot generalization [12] capabilities, offering new opportunities for E2E autonomous driving. Recent efforts have explored dual-system frameworks [13, 14, 15], LLM distillation for enhancing E2E driving [16, 17], and direct trajectory prediction in textual form [18, 19, 20]. While promising, these approaches predominantly operate in open-loop settings or exhibit suboptimal performance in closed-loop evaluations. This limitation stems from their inability to perform context-aware reasoning and robust planning in closed-loop scenarios, where continuous adaptation to dynamic environments is essential [21]. We conclude three key challenges that limit the full exploitation of MLLMs'

-- We consider the problem of traffic density estimation with sparse measurements from stationary roadside sensors. Our approach uses Fourier neural operators to learn macroscopic traffic flow dynamics from high-fidelity data. T o close the loop, we couple the open-loop operator with a correction operator that combines the predicted density with sparse measurements from the sensors. Simulations with the SUMO software indicate that, compared to open-loop observers, the proposed closed-loop observer exhibits classical closed-loop properties such as robustness to noise and ultimate boundedness of the error . This shows the advantages of combining learned physics with real-time corrections, and opens avenues for accurate, efficient, and interpretable data-driven observers.

Real-world adoption of closed-loop insulin delivery systems (CLIDS) in type 1 diabetes remains low, driven not by technical failure, but by diverse behavioral, psychosocial, and social barriers. We introduce ChatCLIDS, the first benchmark to rigorously evaluate LLM-driven persuasive dialogue for health behavior change. Our framework features a library of expert-validated virtual patients, each with clinically grounded, heterogeneous profiles and realistic adoption barriers, and simulates multi-turn interactions with nurse agents equipped with a diverse set of evidence-based persuasive strategies. ChatCLIDS uniquely supports longitudinal counseling and adversarial social influence scenarios, enabling robust, multi-dimensional evaluation. Our findings reveal that while larger and more reflective LLMs adapt strategies over time, all models struggle to overcome resistance, especially under realistic social pressure. These results highlight critical limitations of current LLMs for behavior change, and offer a high-fidelity, scalable testbed for advancing trustworthy persuasive AI in healthcare and beyond.

Future robotic systems operating in real-world environments will require on-board embodied intelligence without continuous cloud connection, balancing capabilities with constraints on computational power and memory. This work presents an extension of the R1-zero approach, which enables the usage of low parameter-count Large Language Models (LLMs) in the robotic domain. The R1-Zero approach was originally developed to enable mathematical reasoning in LLMs using static datasets. We extend it to the robotics domain through integration in a closed-loop Reinforcement Learning (RL) framework. This extension enhances reasoning in Embodied Artificial Intelligence (Embodied AI) settings without relying solely on distillation of large models through Supervised Fine-Tuning (SFT). We show that small-scale LLMs can achieve effective reasoning performance by learning through closed-loop interaction with their environment, which enables tasks that previously required significantly larger models. In an autonomous driving setting, a performance gain of 20.2%-points over the SFT-based baseline is observed with a Qwen2.5-1.5B model. Using the proposed training procedure, Qwen2.5-3B achieves a 63.3% control adaptability score, surpassing the 58.5% obtained by the much larger, cloud-bound GPT-4o. These results highlight that practical, on-board deployment of small LLMs is not only feasible but can outperform larger models if trained through environmental feedback, underscoring the importance of an interactive learning framework for robotic Embodied AI, one grounded in practical experience rather than static supervision.

Humanoid teleoperation plays a vital role in demonstrating and collecting data for complex humanoid-scene interactions. However, current teleoperation systems face critical limitations: they decouple upper- and lower-body control to maintain stability, restricting natural coordination, and operate open-loop without real-time position feedback, leading to accumulated drift. The fundamental challenge is achieving precise, coordinated whole-body teleoperation over extended durations while maintaining accurate global positioning. Here we show that an MoE-based teleoperation system, CLONE, with closed-loop error correction enables unprecedented whole-body teleoperation fidelity, maintaining minimal positional drift over long-range trajectories using only head and hand tracking from an MR headset. Unlike previous methods that either sacrifice coordination for stability or suffer from unbounded drift, CLONE learns diverse motion skills while preventing tracking error accumulation through real-time feedback, enabling complex coordinated movements such as ``picking up objects from the ground.'' These results establish a new milestone for whole-body humanoid teleoperation for long-horizon humanoid-scene interaction tasks.

We present a new application of model checking which achieves real-time multi-step planning and obstacle avoidance on a real autonomous robot. We have developed a small, purpose-built model checking algorithm which generates plans in situ based on "core" knowledge and attention as found in biological agents. This is achieved in real-time using no pre-computed data on a low-powered device. Our approach is based on chaining temporary control systems which are spawned to counteract disturbances in the local environment that disrupt an autonomous agent from its preferred action (or resting state). A novel discretization of 2D LiDAR data sensitive to bounded variations in the local environment is used. Multi-step planning using model checking by forward depth-first search is applied to cul-de-sac and playground scenarios. Both empirical results and informal proofs of two fundamental properties of our approach demonstrate that model checking can be used to create efficient multi-step plans for local obstacle avoidance, improving on the performance of a reactive agent which can only plan one step. Our approach is an instructional case study for the development of safe, reliable and explainable planning in the context of autonomous vehicles.

Many control problems require repeated tuning and adaptation of controllers across distinct closed-loop tasks, where data efficiency and adaptability are critical. We propose a hierarchical Bayesian optimization (BO) framework that is tailored to efficient controller parameter learning in sequential decision-making and control scenarios for distinct tasks. Instead of treating the closed-loop cost as a black-box, our method exploits structural knowledge of the underlying problem, consisting of a dynamical system, a control law, and an associated closed-loop cost function. We construct a hierarchical surrogate model using Gaussian processes that capture the closed-loop state evolution under different parameterizations, while the task-specific weighting and accumulation into the closed-loop cost are computed exactly via known closed-form expressions. This allows knowledge transfer and enhanced data efficiency between different closed-loop tasks. The proposed framework retains sublinear regret guarantees on par with standard black-box BO, while enabling multi-task or transfer learning. Simulation experiments with model predictive control demonstrate substantial benefits in both sample efficiency and adaptability when compared to purely black-box BO approaches.

The advancement of embodied intelligence is accelerating the integration of robots into daily life as human assistants. This evolution requires robots to not only interpret high-level instructions and plan tasks but also perceive and adapt within dynamic environments. Vision-Language Models (VLMs) present a promising solution by combining visual understanding and language reasoning. However, existing VLM-based methods struggle with interactive exploration, accurate perception, and real-time plan adaptation. To address these challenges, we propose ExploreVLM, a novel closed-loop task planning framework powered by Vision-Language Models (VLMs). The framework is built around a step-wise feedback mechanism that enables real-time plan adjustment and supports interactive exploration. At its core is a dual-stage task planner with self-reflection, enhanced by an object-centric spatial relation graph that provides structured, language-grounded scene representations to guide perception and planning. An execution validator supports the closed loop by verifying each action and triggering re-planning. Extensive real-world experiments demonstrate that ExploreVLM significantly outperforms state-of-the-art baselines, particularly in exploration-centric tasks. Ablation studies further validate the critical role of the reflective planner and structured perception in achieving robust and efficient task execution.