Diseases such as autism, cardiovascular disease, and the autoimmune disorders are difficult to treat because of the remarkable degree of variation among affected individuals. Subtyping research seeks to refine the definition of such complex, multi-organ diseases by identifying homogeneous patient subgroups. In this paper, we propose the Probabilistic Subtyping Model (PSM) to identify subgroups based on clustering individual clinical severity markers. This task is challenging due to the presence of nuisance variability — variations in measurements that are not due to disease subtype — which, if not accounted for, generate biased estimates for the group-level trajectories. Measurement sparsity and irregular sampling patterns pose additional challenges in clustering such data. PSM uses a hierarchical model to account for these different sources of variability. Our experiments demonstrate that by accounting for nuisance variability, PSM is able to more accurately model the marker data. We also discuss novel subtypes discovered using PSM and the resulting clinical hypotheses that are now the subject of follow up clinical experiments.

However, model calibration and the learning is critical for many prediction and decision-making of well-calibrated probabilistic models have not been tasks in artificial intelligence. In this paper we present a new studied in the machine learning literature as extensively as nonparametric calibration method called Bayesian Binning for example discriminative machine learning models that into Quantiles (BBQ) which addresses key limitations of existing are built to achieve the best possible discrimination among calibration methods. The method post processes the classes of objects. One way to achieve a high level of model output of a binary classification algorithm; thus, it can be calibration is to develop methods for learning probabilistic readily combined with many existing classification algorithms.

Current algorithms for the standard multi-armed bandit problem have good empirical performance and optimal regret bounds. However, real-world problems often differ from the standard formulation in several ways. First, feedback may be delayed instead of arriving immediately. Second, the real world often contains structure which suggests heuristics, which we wish to incorporate while retaining the best-known theoretical guarantees. Third, we may wish to make use of an arbitrary prior dataset without negatively impacting performance. Fourth, we may wish to efficiently evaluate algorithms using a previously collected dataset. Surprisingly, these seemingly-disparate problems can be addressed using algorithms inspired by a recently-developed queueing technique. We present the Stochastic Delayed Bandits (SDB) algorithm as a solution to these four problems, which takes black-box bandit algorithms (including heuristic approaches) as input while achieving good theoretical guarantees. We present empirical results from both synthetic simulations and real-world data drawn from an educational game. Our results show that SDB outperforms state-of-the-art approaches to handling delay, heuristics, prior data, and evaluation.

We derive a convex optimization problem for the task of segmenting sequential data, which explicitly treats presence of outliers. We describe two algorithms for solving this problem, one exact and one a top-down novel approach, and we derive a consistency results for the case of two segments and no outliers. Robustness to outliers is evaluated on two real-world tasks related to speech segmentation. Our algorithms outperform baseline segmentation algorithms.

Spectral clustering, a graph partitioning technique, has gained immense popularity in machine learning in the context of unsupervised learning. This is due to convincing empirical studies, elegant approaches involved and the theoretical guarantees provided in the literature. To tackle some challenging problems that arose in computer vision etc., recently, a need to develop spectral methods that incorporate multi-way similarity measures surfaced. This, in turn, leads to a hypergraph partitioning problem. In this paper, we formulate a criterion for partitioning uniform hypergraphs, and show that a relaxation of this problem is related to the multilinear singular value decomposition (SVD) of symmetric tensors. Using this, we provide a spectral technique for clustering based on higher order affinities, and derive a theoretical bound on the error incurred by this method. We also study the complexity of the algorithm and use Nystr ̈om’s method and column sampling techniques to develop approximate methods with significantly reduced complexity. Experiments on geometric grouping and motion segmentation demonstrate the practical significance of the proposed methods.

Multiple-Instance (MI) learning is an important supervised learning technique which deals with collections of instances called bags. While existing research in MI learning mainly focused on classification, in this paper we propose a new approach for MI retrieval to enable effective similarity retrieval of bags of instances, where training data is presented in the form of similar and dissimilar bag pairs. An embedded scheme is devised as encoding each bag into a single bag feature vector by exploiting a similarity-based transformation. In this way, the original MI problem is converted into a single-instance version. Furthermore, we develop a principled approach for optimizing bag features specific to similarity retrieval through leveraging pairwise label information at the bag level. The experimental results demonstrate the effectiveness of the proposed approach in comparison with the alternatives for MI retrieval.

In classification problem, we assume that the samples around the class boundary are more likely to be incorrectly annotated than others, and propose boundary-conditional class noise (BCN). Based on the BCN assumption, we use unnormalized Gaussian and Laplace distributions to directly model how class noise is generated, in symmetric and asymmetric cases. In addition, we demonstrate that Logistic regression and Probit regression can also be reinterpreted from this class noise perspective, and compare them with the proposed models. The empirical study shows that, the proposed asymmetric models overall outperform the benchmark linear models, and the asymmetric Laplace-noise model achieves the best performance among all.

Learning for maximizing AUC performance is an important research problem in machine learning. Unlike traditional batch learning methods for maximizing AUC which often suffer from poor scalability, recent years have witnessed some emerging studies that attempt to maximize AUC by single-pass online learning approaches. Despite their encouraging results reported, the existing online AUC maximization algorithms often adopt simple stochastic gradient descent approaches, which fail to exploit the geometry knowledge of the data observed in the online learning process, and thus could suffer from relatively slow convergence. To overcome the limitation of the existing studies, in this paper, we propose a novel algorithm of Adaptive Online AUC Maximization (AdaOAM), by applying an adaptive gradient method for exploiting the knowledge of historical gradients to perform more informative online learning. The new adaptive updating strategy by AdaOAM is less sensitive to parameter settings due to its natural effect of tuning the learning rate. In addition, the time complexity of the new algorithm remains the same as the previous non-adaptive algorithms. To demonstrate the effectiveness of the proposed algorithm, we analyze its theoretical bound, and further evaluate its empirical performance on both public benchmark datasets and anomaly detection datasets. The encouraging empirical results clearly show the effectiveness and efficiency of the proposed algorithm.

Social media platforms are often used by people to express their needs and desires. Such data offer great opportunities to identify users’ consumption intention from user-generated contents, so that better tailored products or services can be recommended. However, there have been few efforts on mining commercial intents from social media contents. In this paper, we investigate the use of social media data to identify consumption intentions for individuals. We develop a Consumption Intention Mining Model (CIMM) based on convolutional neural network (CNN), for identifying whether the user has a consumption intention. The task is domain-dependent, and learning CNN requires a large number of annotated instances, which can be available only in some domains. Hence, we investigate the possibility of transferring the CNN mid-level sentence representation learned from one domain to another by adding an adaptation layer. To demonstrate the effectiveness of CIMM, we conduct experiments on two domains. Our results show that CIMM offers a powerful paradigm for effectively identifying users’ consumption intention based on their social media data. Moreover, our results also confirm that the CNN learned in one domain can be effectively transferred to another domain. This suggests that a great potential for our model to significantly increase effectiveness of product recommendations and targeted advertising.

The n-gram model has been widely used to capture the local ordering of words, yet its exploding feature space often causes an estimation issue. This paper presents local context sparse coding (LCSC), a non-probabilistic topic model that effectively handles large feature spaces using sparse coding. In addition, it introduces a new concept of locality, local contexts, which provides a representation that can generate locally coherent topics and document representations. Our model efficiently finds topics and representations by applying greedy coordinate descent updates. The model is useful for discovering local topics and the semantic flow of a document, as well as constructing predictive models.