Takeda's psoriasis pill developed with AI assistance succeeds in trials Psoriasis is a chronic autoimmune disorder that causes rashes marked by itchy, scaly rashes and afflicts more than 125 million people worldwide. Takeda Pharmaceutical announced that its oral psoriasis drug zasocitinib proved safe and effective in late-stage trials, marking a milestone in its effort to treat the incurable skin condition and offset looming revenue pressure. Patients with moderate-to-severe plaque psoriasis who took the once-daily pill showed significantly clearer skin compared with those on placebo or the existing therapy apremilast, the company said in a statement Thursday. Takeda plans to submit data to the U.S. Food and Drug Administration and other regulators beginning in fiscal year 2026. If approved, zasocitinib would join the small but growing oral psoriasis treatments -- long a market dominated by ointments and injectable antibody therapies -- and stand out as one of the first drugs discovered with the help of artificial intelligence.

Expect big announcements from the likes of Samsung, Sony, NVIDIA and many more. CES doesn't start until January, but whispers of the products and announcements that could be in store for tech's biggest annual conference have already started to take shape. The CES 2026 show floor is officially open from January 6 through 9, although the show kicks off with events on Sunday January 4 and a host of press conferences on Monday. As always, product demos, announcements and networking will be happening at the Las Vegas Convention Center and surrounding hotels all over the city. As usual, Engadget will be covering the event in-person and remotely, bringing you news and hands-ons straight from the show floor.

As OpenAI scrambles to improve ChatGPT, it's ditching a feature in its free tier that contributed to last summer's user revolt. OpenAI has quietly reversed a major change to how hundreds of millions of people use ChatGPT . On a low-profile blog that tracks product changes, the company said that it rolled back ChatGPT's model router--an automated system that sends complicated user questions to more advanced "reasoning" models--for users on its Free and $5-a-month Go tiers. Instead, those users will now default to GPT-5.2 Instant, the fastest and cheapest-to-serve version of OpenAI's new model series. Free and Go users will still be able to access reasoning models, but they will have to select them manually.

In October, the company announced plans to fire 14,000 employees globally amid its deepening embrace of AI. Amazon's logo on the side of a logistics center. Amazon is set to fire 370 people at its European headquarters in Luxembourg in the coming weeks, as reports. Amazon initially planned to reduce its headcount there by 470, but under European Union law, companies have to negotiate layoffs with employee reps and, in some cases, governments. Amazon reportedly told employees at the European HQ in a memo the layoffs are adjustments that reflect business needs and local strategies.

OpenAI releases GPT-5.2 to take on Google and Anthropic The new model is all about professional work. OpenAI's code red response to Google's Gemini 3 Pro has arrived . On the same day the company announced a Sora licensing pact with Disney, it took the wraps off GPT-5.2 . OpenAI is touting the new model as its best yet for real-world, professional use. "It's better at creating spreadsheets, building presentations, writing code, perceiving images, understanding long contexts, using tools, and handling complex, multi-step projects," said OpenAI.

Disney and OpenAI have made a surprise deal - what happens next? Disney's famous Mickey Mouse character will soon be available for use in AI-generated videos The world's best-known AI company and the world's best-known entertainment firm have come to a surprise agreement to allow AI versions of some of the most iconic characters in film, TV and cartoons to be used in generative AI videos and images. Social media is dead - here's what comes next The Walt Disney Company has signed a deal with OpenAI that will allow the AI firm's Sora video generation tool and ChatGPT image creator to use more than 200 of Disney's most iconic characters. Meanwhile, Disney remains in dispute with another AI firm, Midjourney, over alleged infringement of their intellectual property (IP), claiming Midjourney aims to "blatantly incorporate and copy Disney's and Universal's famous characters" into their image generating tool. The characters now deemed fair game for OpenAI users include the likes of Mickey and Minnie Mouse, Simba and Mufasa from and Moana, as well as Marvel and Lucasfilm characters, including some of's most well-known names.

Official court press releases from Germany's highest courts present and explain judicial rulings to the public, as well as to expert audiences. Prior NLP efforts emphasize technical headnotes, ignoring citizen-oriented communication needs. We introduce CourtPressGER, a 6.4k dataset of triples: rulings, human-drafted press releases, and synthetic prompts for LLMs to generate comparable releases. This benchmark trains and evaluates LLMs in generating accurate, readable summaries from long judicial texts. We benchmark small and large LLMs using reference-based metrics, factual-consistency checks, LLM-as-judge, and expert ranking. Large LLMs produce high-quality drafts with minimal hierarchical performance loss; smaller models require hierarchical setups for long judgments. Initial benchmarks show varying model performance, with human-drafted releases ranking highest.

GPU prices could follow RAM's big rise Slack's CEO is joining OpenAI to find the money to pay for all those data centers Slack CEO Denise Dresser is OpenAI's new Chief Revenue Officer. OpenAI has announced that Denise Dresser, the current CEO of Slack, will be the company's new Chief Revenue Officer. Dresser will oversee the company's revenue strategy across enterprise and customer success, according to OpenAI's announcement, and will presumably play a key role in leading the company towards profitability now that it's reorganized as a public benefit corporation . We're on a path to put AI tools into the hands of millions of workers, across every industry, Fidji Simo, OpenAI's CEO of Products said in the announcement. Denise has led that kind of shift before, and her experience will help us make AI useful, reliable, and accessible for businesses everywhere.

When you purchase through links in our articles, we may earn a small commission. Everything is free, though the AI will eventually charge a fee. While the iFixit app for both Android and iOS will be free, the new FixBot may not be. The company's plan is to make it free for now, then split it off into a free tier with access limits and then a paid Enthusiast tier with voice and document upload, according to the company. That tier will cost $4.99 per month or $50 per year, the company said.

When you purchase through links in our articles, we may earn a small commission. I hope Crucial's death isn't a canary in a PC memory coal mine I'm now wondering what comes next. I did not have "Micron kills its consumer business" on my 2025 bingo card. The company announced the shuttering of its Crucial brand on Wednesday morning in unexpectedly simple, transparent language . The short version: Micron is concentrating on their business customers, where the demand has "surged" for memory and storage--thanks to data centers and their scaling up for AI.