Diffusion models have demonstrated exceptional efficacy in various generative applications. While existing models focus on minimizing a weighted sum of denoising score matching losses for data distribution modeling, their training primarily emphasizes instance-level optimization, overlooking valuable structural information within each mini-batch, indicative of pair-wise relationships among samples. To address this limitation, we introduce Structure-guided Adversarial training of Diffusion Models (SADM). In this pioneering approach, we compel the model to learn manifold structures between samples in each training batch. To ensure the model captures authentic manifold structures in the data distribution, we advocate adversarial training of the diffusion generator against a novel structure discriminator in a minimax game, distinguishing real manifold structures from the generated ones. SADM substantially improves existing diffusion transformers (DiT) and outperforms existing methods in image generation and cross-domain fine-tuning tasks across 12 datasets, establishing a new state-of-the-art FID of 1.58 and 2.11 on ImageNet for class-conditional image generation at resolutions of 256x256 and 512x512, respectively.

The significance of learning constraints from data is underscored by its potential applications in real-world problem-solving. While constraints are popular for modeling and solving, the approaches to learning constraints from data remain relatively scarce. Furthermore, the intricate task of modeling demands expertise and is prone to errors, thus constraint acquisition methods offer a solution by automating this process through learnt constraints from examples or behaviours of solutions and non-solutions. This work introduces a novel approach grounded in Deep Neural Network (DNN) based on Symbolic Regression that, by setting suitable loss functions, constraints can be extracted directly from datasets. Using the present approach, direct formulation of constraints was achieved. Furthermore, given the broad pre-developed architectures and functionalities of DNN, connections and extensions with other frameworks could be foreseen.

This paper presents a comprehensive overview of the Comparative Opinion Mining from Vietnamese Product Reviews shared task (ComOM), held as part of the 10$^{th}$ International Workshop on Vietnamese Language and Speech Processing (VLSP 2023). The primary objective of this shared task is to advance the field of natural language processing by developing techniques that proficiently extract comparative opinions from Vietnamese product reviews. Participants are challenged to propose models that adeptly extract a comparative "quintuple" from a comparative sentence, encompassing Subject, Object, Aspect, Predicate, and Comparison Type Label. We construct a human-annotated dataset comprising $120$ documents, encompassing $7427$ non-comparative sentences and $2468$ comparisons within $1798$ sentences. Participating models undergo evaluation and ranking based on the Exact match macro-averaged quintuple F1 score.

Machine learning models, while progressively advanced, rely heavily on the IID assumption, which is often unfulfilled in practice due to inevitable distribution shifts. This renders them susceptible and untrustworthy for deployment in risk-sensitive applications. Such a significant problem has consequently spawned various branches of works dedicated to developing algorithms capable of Out-of-Distribution (OOD) generalization. Despite these efforts, much less attention has been paid to the evaluation of OOD generalization, which is also a complex and fundamental problem. Its goal is not only to assess whether a model's OOD generalization capability is strong or not, but also to evaluate where a model generalizes well or poorly. This entails characterizing the types of distribution shifts that a model can effectively address, and identifying the safe and risky input regions given a model. This paper serves as the first effort to conduct a comprehensive review of OOD evaluation. We categorize existing research into three paradigms: OOD performance testing, OOD performance prediction, and OOD intrinsic property characterization, according to the availability of test data. Additionally, we briefly discuss OOD evaluation in the context of pretrained models. In closing, we propose several promising directions for future research in OOD evaluation.

Three-Dimensional (3D) chromatin interactions, such as enhancer-promoter interactions (EPIs), loops, Topologically Associating Domains (TADs), and A/B compartments play critical roles in a wide range of cellular processes by regulating gene expression. Recent development of chromatin conformation capture technologies has enabled genome-wide profiling of various 3D structures, even with single cells. However, current catalogs of 3D structures remain incomplete and unreliable due to differences in technology, tools, and low data resolution. Machine learning methods have emerged as an alternative to obtain missing 3D interactions and/or improve resolution. Such methods frequently use genome annotation data (ChIP-seq, DNAse-seq, etc.), DNA sequencing information (k-mers, Transcription Factor Binding Site (TFBS) motifs), and other genomic properties to learn the associations between genomic features and chromatin interactions. In this review, we discuss computational tools for predicting three types of 3D interactions (EPIs, chromatin interactions, TAD boundaries) and analyze their pros and cons. We also point out obstacles of computational prediction of 3D interactions and suggest future research directions.

This book aims to provide a working introduction to the emerging fusion of modern statistical inference - aka machine learning (ML) or artificial intelligence (AI) - and causal inference methods. The book is aimed at upper level undergraduates and master's-level students as well as doctoral students focusing on applied empirical research. A sufficient background for the core material is one semester of introductory econometrics and one semester of machine learning. We hope the book is also useful to empirical researchers looking to apply modern methods in their work. The book provides an overview of key ideas in both predictive inference and causal inference and shows how predictive tools are key ingredients to answering many causal questions.

Time-series modeling in process industries faces the challenge of dealing with complex, multi-faceted, and evolving data characteristics. Conventional single model approaches often struggle to capture the interplay of diverse dynamics, resulting in suboptimal forecasts. Addressing this, we introduce the Recency-Weighted Temporally-Segmented (ReWTS, pronounced `roots') ensemble model, a novel chunk-based approach for multi-step forecasting. The key characteristics of the ReWTS model are twofold: 1) It facilitates specialization of models into different dynamics by segmenting the training data into `chunks' of data and training one model per chunk. 2) During inference, an optimization procedure assesses each model on the recent past and selects the active models, such that the appropriate mixture of previously learned dynamics can be recalled to forecast the future. This method not only captures the nuances of each period, but also adapts more effectively to changes over time compared to conventional `global' models trained on all data in one go. We present a comparative analysis, utilizing two years of data from a wastewater treatment plant and a drinking water treatment plant in Norway, demonstrating the ReWTS ensemble's superiority. It consistently outperforms the global model in terms of mean squared forecasting error across various model architectures by 10-70\% on both datasets, notably exhibiting greater resilience to outliers. This approach shows promise in developing automatic, adaptable forecasting models for decision-making and control systems in process industries and other complex systems.

Music-based reminiscence has the potential to positively impact the psychological well-being of older adults. However, the aging process and physiological changes, such as memory decline and limited verbal communication, may impede the ability of older adults to recall their memories and life experiences. Given the advanced capabilities of generative artificial intelligence (AI) systems, such as generated conversations and images, and their potential to facilitate the reminiscing process, this study aims to explore the design of generative AI to support music-based reminiscence in older adults. This study follows a user-centered design approach incorporating various stages, including detailed interviews with two social workers and two design workshops (involving ten older adults). Our work contributes to an in-depth understanding of older adults' attitudes toward utilizing generative AI for supporting music-based reminiscence and identifies concrete design considerations for the future design of generative AI to enhance the reminiscence experience of older adults.

In the current machine translation (MT) landscape, the Transformer architecture stands out as the gold standard, especially for high-resource language pairs. This research delves into its efficacy for low-resource language pairs including both the English$\leftrightarrow$Irish and English$\leftrightarrow$Marathi language pairs. Notably, the study identifies the optimal hyperparameters and subword model type to significantly improve the translation quality of Transformer models for low-resource language pairs. The scarcity of parallel datasets for low-resource languages can hinder MT development. To address this, gaHealth was developed, the first bilingual corpus of health data for the Irish language. Focusing on the health domain, models developed using this in-domain dataset exhibited very significant improvements in BLEU score when compared with models from the LoResMT2021 Shared Task. A subsequent human evaluation using the multidimensional quality metrics error taxonomy showcased the superior performance of the Transformer system in reducing both accuracy and fluency errors compared to an RNN-based counterpart. Furthermore, this thesis introduces adaptNMT and adaptMLLM, two open-source applications streamlined for the development, fine-tuning, and deployment of neural machine translation models. These tools considerably simplify the setup and evaluation process, making MT more accessible to both developers and translators. Notably, adaptNMT, grounded in the OpenNMT ecosystem, promotes eco-friendly natural language processing research by highlighting the environmental footprint of model development. Fine-tuning of MLLMs by adaptMLLM demonstrated advancements in translation performance for two low-resource language pairs: English$\leftrightarrow$Irish and English$\leftrightarrow$Marathi, compared to baselines from the LoResMT2021 Shared Task.

Knowledge graphs have garnered significant research attention and are widely used to enhance downstream applications. However, most current studies mainly focus on static knowledge graphs, whose facts do not change with time, and disregard their dynamic evolution over time. As a result, temporal knowledge graphs have attracted more attention because a large amount of structured knowledge exists only within a specific period. Knowledge graph representation learning aims to learn low-dimensional vector embeddings for entities and relations in a knowledge graph. The representation learning of temporal knowledge graphs incorporates time information into the standard knowledge graph framework and can model the dynamics of entities and relations over time. In this paper, we conduct a comprehensive survey of temporal knowledge graph representation learning and its applications. We begin with an introduction to the definitions, datasets, and evaluation metrics for temporal knowledge graph representation learning. Next, we propose a taxonomy based on the core technologies of temporal knowledge graph representation learning methods, and provide an in-depth analysis of different methods in each category. Finally, we present various downstream applications related to the temporal knowledge graphs. In the end, we conclude the paper and have an outlook on the future research directions in this area.