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AI for Biomedicine in the Era of Large Language Models

arXiv.org Artificial Intelligence

The capabilities of AI for biomedicine span a wide spectrum, from the atomic level, where it solves partial differential equations for quantum systems, to the molecular level, predicting chemical or protein structures, and further extending to societal predictions like infectious disease outbreaks. Recent advancements in large language models, exemplified by models like ChatGPT, have showcased significant prowess in natural language tasks, such as translating languages, constructing chatbots, and answering questions. When we consider biomedical data, we observe a resemblance to natural language in terms of sequences: biomedical literature and health records presented as text, biological sequences or sequencing data arranged in sequences, or sensor data like brain signals as time series. The question arises: Can we harness the potential of recent large language models to drive biomedical knowledge discoveries? In this survey, we will explore the application of large language models to three crucial categories of biomedical data: 1) textual data, 2) biological sequences, and 3) brain signals. Furthermore, we will delve into large language model challenges in biomedical research, including ensuring trustworthiness, achieving personalization, and adapting to multi-modal data representation


Analyzing Male Domestic Violence through Exploratory Data Analysis and Explainable Machine Learning Insights

arXiv.org Artificial Intelligence

Domestic violence, which is often perceived as a gendered issue among female victims, has gained increasing attention in recent years. Despite this focus, male victims of domestic abuse remain primarily overlooked, particularly in Bangladesh. Our study represents a pioneering exploration of the underexplored realm of male domestic violence (MDV) within the Bangladeshi context, shedding light on its prevalence, patterns, and underlying factors. Existing literature predominantly emphasizes female victimization in domestic violence scenarios, leading to an absence of research on male victims. We collected data from the major cities of Bangladesh and conducted exploratory data analysis to understand the underlying dynamics. We implemented 11 traditional machine learning models with default and optimized hyperparameters, 2 deep learning, and 4 ensemble models. Despite various approaches, CatBoost has emerged as the top performer due to its native support for categorical features, efficient handling of missing values, and robust regularization techniques, achieving 76% accuracy. In contrast, other models achieved accuracy rates in the range of 58-75%. The eXplainable AI techniques, SHAP and LIME, were employed to gain insights into the decision-making of black-box machine learning models. By shedding light on this topic and identifying factors associated with domestic abuse, the study contributes to identifying groups of people vulnerable to MDV, raising awareness, and informing policies and interventions aimed at reducing MDV. Our findings challenge the prevailing notion that domestic abuse primarily affects women, thus emphasizing the need for tailored interventions and support systems for male victims. ML techniques enhance the analysis and understanding of the data, providing valuable insights for developing effective strategies to combat this pressing social issue.


A2DMN: Anatomy-Aware Dilated Multiscale Network for Breast Ultrasound Semantic Segmentation

arXiv.org Artificial Intelligence

In recent years, convolutional neural networks for semantic segmentation of breast ultrasound (BUS) images have shown great success; however, two major challenges still exist. 1) Most current approaches inherently lack the ability to utilize tissue anatomy, resulting in misclassified image regions. 2) They struggle to produce accurate boundaries due to the repeated down-sampling operations. To address these issues, we propose a novel breast anatomy-aware network for capturing fine image details and a new smoothness term that encodes breast anatomy. It incorporates context information across multiple spatial scales to generate more accurate semantic boundaries. Extensive experiments are conducted to compare the proposed method and eight state-of-the-art approaches using a BUS dataset with 325 images. The results demonstrate the proposed method significantly improves the segmentation of the muscle, mammary, and tumor classes and produces more accurate fine details of tissue boundaries.


Unifying Lane-Level Traffic Prediction from a Graph Structural Perspective: Benchmark and Baseline

arXiv.org Artificial Intelligence

Traffic prediction has long been a focal and pivotal area in research, witnessing both significant strides from city-level to road-level predictions in recent years. With the advancement of Vehicle-to-Everything (V2X) technologies, autonomous driving, and large-scale models in the traffic domain, lane-level traffic prediction has emerged as an indispensable direction. However, further progress in this field is hindered by the absence of comprehensive and unified evaluation standards, coupled with limited public availability of data and code. This paper extensively analyzes and categorizes existing research in lane-level traffic prediction, establishes a unified spatial topology structure and prediction tasks, and introduces a simple baseline model, GraphMLP, based on graph structure and MLP networks. We have replicated codes not publicly available in existing studies and, based on this, thoroughly and fairly assessed various models in terms of effectiveness, efficiency, and applicability, providing insights for practical applications. Additionally, we have released three new datasets and corresponding codes to accelerate progress in this field, all of which can be found on https://github.com/ShuhaoLii/TITS24LaneLevel-Traffic-Benchmark.


Towards Knowledge-Grounded Natural Language Understanding and Generation

arXiv.org Artificial Intelligence

This thesis investigates how natural language understanding and generation with transformer models can benefit from grounding the models with knowledge representations. Currently, the most prevailing paradigm for training language models is through pre-training on abundant raw text data and fine-tuning on downstream tasks. Although language models continue to advance, especially the recent trend of Large Language Models (LLMs) such as ChatGPT, there seem to be limits to what can be achieved with text data alone and it is desirable to study the impact of applying and integrating rich forms of knowledge representation to improve model performance. The most widely used form of knowledge for language modelling is structured knowledge in the form of triples consisting of entities and their relationships, often in English. This thesis explores beyond this conventional approach and aims to address several key questions: Can knowledge of entities extend its benefits beyond entity-centric tasks such as entity linking? How can we faithfully and effectively extract such structured knowledge from raw text, especially noisy web text? How do other types of knowledge, beyond structured knowledge, contribute to improving NLP tasks?


An Exploratory Investigation into Code License Infringements in Large Language Model Training Datasets

arXiv.org Artificial Intelligence

Does the training of large language models potentially infringe upon code licenses? Furthermore, are there any datasets available that can be safely used for training these models without violating such licenses? In our study, we assess the current trends in the field and the importance of incorporating code into the training of large language models. Additionally, we examine publicly available datasets to see whether these models can be trained on them without the risk of legal issues in the future. To accomplish this, we compiled a list of 53 large language models trained on file-level code. We then extracted their datasets and analyzed how much they overlap with a dataset we created, consisting exclusively of strong copyleft code. Our analysis revealed that every dataset we examined contained license inconsistencies, despite being selected based on their associated repository licenses. We analyzed a total of 514 million code files, discovering 38 million exact duplicates present in our strong copyleft dataset. Additionally, we examined 171 million file-leading comments, identifying 16 million with strong copyleft licenses and another 11 million comments that discouraged copying without explicitly mentioning a license. Based on the findings of our study, which highlights the pervasive issue of license inconsistencies in large language models trained on code, our recommendation for both researchers and the community is to prioritize the development and adoption of best practices for dataset creation and management.


KoCoSa: Korean Context-aware Sarcasm Detection Dataset

arXiv.org Artificial Intelligence

Sarcasm is a way of verbal irony where someone says the opposite of what they mean, often to ridicule a person, situation, or idea. It is often difficult to detect sarcasm in the dialogue since detecting sarcasm should reflect the context (i.e., dialogue history). In this paper, we introduce a new dataset for the Korean dialogue sarcasm detection task, KoCoSa (Korean Context-aware Sarcasm Detection Dataset), which consists of 12.8K daily Korean dialogues and the labels for this task on the last response. To build the dataset, we propose an efficient sarcasm detection dataset generation pipeline: 1) generating new sarcastic dialogues from source dialogues with large language models, 2) automatic and manual filtering of abnormal and toxic dialogues, and 3) human annotation for the sarcasm detection task. We also provide a simple but effective baseline for the Korean sarcasm detection task trained on our dataset. Experimental results on the dataset show that our baseline system outperforms strong baselines like large language models, such as GPT-3.5, in the Korean sarcasm detection task. We show that the sarcasm detection task relies deeply on the existence of sufficient context.


ChatGPT Alternative Solutions: Large Language Models Survey

arXiv.org Artificial Intelligence

In recent times, the grandeur of Large Language Models (LLMs) has not only shone in the realm of natural language processing but has also cast its brilliance across a vast array of applications. This remarkable display of LLM capabilities has ignited a surge in research contributions within this domain, spanning a diverse spectrum of topics. These contributions encompass advancements in neural network architecture, context length enhancements, model alignment, training datasets, benchmarking, efficiency improvements, and more. Recent years have witnessed a dynamic synergy between academia and industry, propelling the field of LLM research to new heights. A notable milestone in this journey is the introduction of ChatGPT, a powerful AI chatbot grounded in LLMs, which has garnered widespread societal attention. The evolving technology of LLMs has begun to reshape the landscape of the entire AI community, promising a revolutionary shift in the way we create and employ AI algorithms. Given this swift-paced technical evolution, our survey embarks on a journey to encapsulate the recent strides made in the world of LLMs. Through an exploration of the background, key discoveries, and prevailing methodologies, we offer an up-to-the-minute review of the literature. By examining multiple LLM models, our paper not only presents a comprehensive overview but also charts a course that identifies existing challenges and points toward potential future research trajectories.


A Comparative Study of Real-Time Implementable Cooperative Aerial Manipulation Systems

arXiv.org Artificial Intelligence

Research and development in Unmanned Aerial Vehicles (UAVs) or Unmanned Aircraft Systems (UAS) has witnessed unprecedented scientific and commercial interest and growth, particularly during the last two decades. Although military applications dominated the global market for years, interest in using UAVs in civil and public domains increases exponentially, worldwide, albeit challenges related to integrating unmanned aviation into the national airspace. Sample applications include, but are not limited to, surveillance [1], search and rescue [2], aerial photography [3], fire monitoring [4], agriculture [5], and aerial delivery [6]. The listed applications refer to solely passive tasks, that is, tasks in which no UAV interaction with the environment is needed. However, contact with the environment is required in industrial and maintenance applications like bridge inspection, water damn inspection, high-voltage transmission line inspection [7], assembly tasks [8] or construction [9].


Advancing Frontiers in SLAM: A Survey of Symbolic Representation and Human-Machine Teaming in Environmental Mapping

arXiv.org Artificial Intelligence

This survey paper presents a comprehensive overview of the latest advancements in the field of Simultaneous Localization and Mapping (SLAM) with a focus on the integration of symbolic representation of environment features. The paper synthesizes research trends in multi-agent systems (MAS) and human-machine teaming, highlighting their applications in both symbolic and sub-symbolic SLAM tasks. The survey emphasizes the evolution and significance of ontological designs and symbolic reasoning in creating sophisticated 2D and 3D maps of various environments. Central to this review is the exploration of different architectural approaches in SLAM, with a particular interest in the functionalities and applications of edge and control agent architectures in MAS settings. This study acknowledges the growing demand for enhanced human-machine collaboration in mapping tasks and examines how these collaborative efforts improve the accuracy and efficiency of environmental mapping