Applications of Generative AI (Gen AI) are expected to revolutionize a number of different areas, ranging from science & medicine to education. The potential for these seismic changes has triggered a lively debate about the potential risks of the technology, and resulted in calls for tighter regulation, in particular from some of the major tech companies who are leading in AI development. This regulation is likely to put at risk the budding field of open-source generative AI. Using a three-stage framework for Gen AI development (near, mid and long-term), we analyze the risks and opportunities of open-source generative AI models with similar capabilities to the ones currently available (near to mid-term) and with greater capabilities (long-term). We argue that, overall, the benefits of open-source Gen AI outweigh its risks. As such, we encourage the open sourcing of models, training and evaluation data, and provide a set of recommendations and best practices for managing risks associated with open-source generative AI.

Effective evaluation of language models remains an open challenge in NLP. Researchers and engineers face methodological issues such as the sensitivity of models to evaluation setup, difficulty of proper comparisons across methods, and the lack of reproducibility and transparency. In this paper we draw on three years of experience in evaluating large language models to provide guidance and lessons for researchers. First, we provide an overview of common challenges faced in language model evaluation. Second, we delineate best practices for addressing or lessening the impact of these challenges on research. Third, we present the Language Model Evaluation Harness (lm-eval): an open source library for independent, reproducible, and extensible evaluation of language models that seeks to address these issues. We describe the features of the library as well as case studies in which the library has been used to alleviate these methodological concerns.

Since the inception of the Transformer architecture in 2017, Large Language Models (LLMs) such as GPT and BERT have evolved significantly, impacting various industries with their advanced capabilities in language understanding and generation. These models have shown potential to transform the medical field, highlighting the necessity for specialized evaluation frameworks to ensure their effective and ethical deployment. This comprehensive survey delineates the extensive application and requisite evaluation of LLMs within healthcare, emphasizing the critical need for empirical validation to fully exploit their capabilities in enhancing healthcare outcomes. Our survey is structured to provide an in-depth analysis of LLM applications across clinical settings, medical text data processing, research, education, and public health awareness. We begin by exploring the roles of LLMs in various medical applications, detailing their evaluation based on performance in tasks such as clinical diagnosis, medical text data processing, information retrieval, data analysis, and educational content generation. The subsequent sections offer a comprehensive discussion on the evaluation methods and metrics employed, including models, evaluators, and comparative experiments. We further examine the benchmarks and datasets utilized in these evaluations, providing a categorized description of benchmarks for tasks like question answering, summarization, information extraction, bioinformatics, information retrieval and general comprehensive benchmarks. This structure ensures a thorough understanding of how LLMs are assessed for their effectiveness, accuracy, usability, and ethical alignment in the medical domain. ...

Machine learning techniques are steadily becoming more important in modern biology, and are used to build predictive models, discover patterns, and investigate biological problems. However, models trained on one dataset are often not generalizable to other datasets from different cohorts or laboratories, due to differences in the statistical properties of these datasets. These could stem from technical differences, such as the measurement technique used, or from relevant biological differences between the populations studied. Domain adaptation, a type of transfer learning, can alleviate this problem by aligning the statistical distributions of features and samples among different datasets so that similar models can be applied across them. However, a majority of state-of-the-art domain adaptation methods are designed to work with large-scale data, mostly text and images, while biological datasets often suffer from small sample sizes, and possess complexities such as heterogeneity of the feature space. This Review aims to synthetically discuss domain adaptation methods in the context of small-scale and highly heterogeneous biological data. We describe the benefits and challenges of domain adaptation in biological research and critically discuss some of its objectives, strengths, and weaknesses through key representative methodologies. We argue for the incorporation of domain adaptation techniques to the computational biologist's toolkit, with further development of customized approaches. Keywords: Machine learning; biological-scale datasets; small datasets; neuroimaging; microbiome; domain adaptation; transfer learning.

Explanation generation frameworks aim to make AI systems' decisions transparent and understandable to human users. However, generating explanations in uncertain environments characterized by incomplete information and probabilistic models remains a significant challenge. In this paper, we propose a novel framework for generating probabilistic monolithic explanations and model reconciling explanations. Monolithic explanations provide self-contained reasons for an explanandum without considering the agent receiving the explanation, while model reconciling explanations account for the knowledge of the agent receiving the explanation. For monolithic explanations, our approach integrates uncertainty by utilizing probabilistic logic to increase the probability of the explanandum. For model reconciling explanations, we propose a framework that extends the logic-based variant of the model reconciliation problem to account for probabilistic human models, where the goal is to find explanations that increase the probability of the explanandum while minimizing conflicts between the explanation and the probabilistic human model. We introduce explanatory gain and explanatory power as quantitative metrics to assess the quality of these explanations. Further, we present algorithms that exploit the duality between minimal correction sets and minimal unsatisfiable sets to efficiently compute both types of explanations in probabilistic contexts. Extensive experimental evaluations on various benchmarks demonstrate the effectiveness and scalability of our approach in generating explanations under uncertainty.

While 3D MLLMs have achieved significant progress, they are restricted to object and scene understanding and struggle to understand 3D spatial structures at the part level. In this paper, we introduce Kestrel, representing a novel approach that empowers 3D MLLMs with part-aware understanding, enabling better interpretation and segmentation grounding of 3D objects at the part level. Despite its significance, the current landscape lacks tasks and datasets that endow and assess this capability. Therefore, we propose two novel tasks: (1) Part-Aware Point Grounding, the model is tasked with directly predicting a part-level segmentation mask based on user instructions, and (2) Part-Aware Point Grounded Captioning, the model provides a detailed caption that includes part-level descriptions and their corresponding masks. To support learning and evaluating for these tasks, we introduce 3DCoMPaT Grounded Instructions Dataset (3DCoMPaT-GRIN). 3DCoMPaT-GRIN Vanilla, comprising 789k part-aware point cloud-instruction-segmentation mask triplets, is used to evaluate MLLMs' ability of part-aware segmentation grounding. 3DCoMPaT-GRIN Grounded Caption, containing 107k part-aware point cloud-instruction-grounded caption triplets, assesses both MLLMs' part-aware language comprehension and segmentation grounding capabilities. Our introduced tasks, dataset, and Kestrel represent a preliminary effort to bridge the gap between human cognition and 3D MLLMs, i.e., the ability to perceive and engage with the environment at both global and part levels. Extensive experiments on the 3DCoMPaT-GRIN show that Kestrel can generate user-specified segmentation masks, a capability not present in any existing 3D MLLM. Kestrel thus established a benchmark for evaluating the part-aware language comprehension and segmentation grounding of 3D objects. Project page at https://feielysia.github.io/Kestrel.github.io/

The digital transformation of modern cities by integrating advanced information, communication, and computing technologies has marked the epoch of data-driven smart city applications for efficient and sustainable urban management. Despite their effectiveness, these applications often rely on massive amounts of high-dimensional and multi-domain data for monitoring and characterizing different urban sub-systems, presenting challenges in application areas that are limited by data quality and availability, as well as costly efforts for generating urban scenarios and design alternatives. As an emerging research area in deep learning, Generative Artificial Intelligence (AI) models have demonstrated their unique values in data and code generation. This survey paper aims to explore the innovative integration of generative AI techniques and urban digital twins to address challenges in the realm of smart cities in various urban sectors, such as transportation and mobility management, energy system operations, building and infrastructure management, and urban design. The survey starts with the introduction of popular generative AI models with their application areas, followed by a structured review of the existing urban science applications that leverage the autonomous capability of the generative AI techniques to facilitate (a) data augmentation for promoting urban monitoring and predictive analytics, (b) synthetic data and scenario generation, (c) automated 3D city modeling, and (d) generative urban design and optimization. Based on the review, this survey discusses potential opportunities and technical strategies that integrate generative AI models into the next-generation urban digital twins for more reliable, scalable, and automated management of smart cities.

Recent advances in text-to-music editing, which employ text queries to modify music (e.g. by changing its style or adjusting instrumental components), present unique challenges and opportunities for AI-assisted music creation. Previous approaches in this domain have been constrained by the necessity to train specific editing models from scratch, which is both resource-intensive and inefficient; other research uses large language models to predict edited music, resulting in imprecise audio reconstruction. To Combine the strengths and address these limitations, we introduce Instruct-MusicGen, a novel approach that finetunes a pretrained MusicGen model to efficiently follow editing instructions such as adding, removing, or separating stems. Our approach involves a modification of the original MusicGen architecture by incorporating a text fusion module and an audio fusion module, which allow the model to process instruction texts and audio inputs concurrently and yield the desired edited music. Remarkably, Instruct-MusicGen only introduces 8% new parameters to the original MusicGen model and only trains for 5K steps, yet it achieves superior performance across all tasks compared to existing baselines, and demonstrates performance comparable to the models trained for specific tasks. This advancement not only enhances the efficiency of text-to-music editing but also broadens the applicability of music language models in dynamic music production environments.

We derive a novel, provably robust, and closed-form Bayesian update rule for online filtering in state-space models in the presence of outliers and misspecified measurement models. Our method combines generalised Bayesian inference with filtering methods such as the extended and ensemble Kalman filter. We use the former to show robustness and the latter to ensure computational efficiency in the case of nonlinear models. Our method matches or outperforms other robust filtering methods (such as those based on variational Bayes) at a much lower computational cost. We show this empirically on a range of filtering problems with outlier measurements, such as object tracking, state estimation in high-dimensional chaotic systems, and online learning of neural networks.

Safety limitations in service robotics across various industries have raised significant concerns about the need for robust mechanisms ensuring that robots adhere to safe practices, thereby preventing actions that might harm humans or cause property damage. Despite advances, including the integration of Knowledge Graphs (KGs) with Large Language Models (LLMs), challenges in ensuring consistent safety in autonomous robot actions persist. In this paper, we propose a novel integration of Large Language Models with Embodied Robotic Control Prompts (ERCPs) and Embodied Knowledge Graphs (EKGs) to enhance the safety framework for service robots. ERCPs are designed as predefined instructions that ensure LLMs generate safe and precise responses. These responses are subsequently validated by EKGs, which provide a comprehensive knowledge base ensuring that the actions of the robot are continuously aligned with safety protocols, thereby promoting safer operational practices in varied contexts. Our experimental setup involved diverse real-world tasks, where robots equipped with our framework demonstrated significantly higher compliance with safety standards compared to traditional methods. This integration fosters secure human-robot interactions and positions our methodology at the forefront of AI-driven safety innovations in service robotics.