Predicting external hand load from sensor data is essential for ergonomic exposure assessments, as obtaining this information typically requires direct observation or supplementary data. While machine learning methods have been used to estimate external hand load from worker postures or force exertion data, our findings reveal systematic bias in these predictions due to individual differences such as age and biological sex. To explore this issue, we examined bias in hand load prediction by varying the sex ratio in the training dataset. We found substantial sex disparity in predictive performance, especially when the training dataset is more sex-imbalanced. To address this bias, we developed and evaluated a fair predictive model for hand load estimation that leverages a Variational Autoencoder (VAE) with feature disentanglement. This approach is designed to separate sex-agnostic and sex-specific latent features, minimizing feature overlap. The disentanglement capability enables the model to make predictions based solely on sex-agnostic features of motion patterns, ensuring fair prediction for both biological sexes. Our proposed fair algorithm outperformed conventional machine learning methods (e.g., Random Forests) in both fairness and predictive accuracy, achieving a lower mean absolute error (MAE) difference across male and female sets and improved fairness metrics such as statistical parity (SP) and positive and negative residual differences (PRD and NRD), even when trained on imbalanced sex datasets. These findings emphasize the importance of fairness-aware machine learning algorithms to prevent potential disadvantages in workplace health and safety for certain worker populations.

While Large Language Models (LLMs) acquire vast knowledge during pre-training, they often lack domain-specific, new, or niche information. Continual pre-training (CPT) attempts to address this gap but suffers from catastrophic forgetting and inefficiencies in low-data regimes. We introduce Knowledge-Instruct, a novel approach to efficiently inject knowledge from limited corpora through pure instruction-tuning. By generating information-dense synthetic instruction data, it effectively integrates new knowledge while preserving general reasoning and instruction-following abilities. Knowledge-Instruct demonstrates superior factual memorization, minimizes catastrophic forgetting, and remains scalable by leveraging synthetic data from relatively small language models. Additionally, it enhances contextual understanding, including complex multi-hop reasoning, facilitating integration with retrieval systems. We validate its effectiveness across diverse benchmarks, including Companies, a new dataset that we release to measure knowledge injection capabilities.

We assess how the code reasoning abilities of large language models (LLMs) generalize to different kinds of programs. We present techniques for obtaining in- and out-of-distribution programs with different characteristics: code sampled from a domain-specific language, code automatically generated by an LLM, code collected from competitive programming contests, and mutated versions of these programs. We also present an experimental methodology for evaluating LLM generalization by comparing their performance on these programs. We perform an extensive evaluation across 10 state-of-the-art models from the past year, obtaining insights into their generalization capabilities over time and across different classes of programs. Our results highlight that while earlier models exhibit behavior consistent with pattern matching, the latest models exhibit strong generalization abilities on code reasoning.

Hypothesis generation is a fundamental step in scientific discovery, yet it is increasingly challenged by information overload and disciplinary fragmentation. Recent advances in Large Language Models (LLMs) have sparked growing interest in their potential to enhance and automate this process. This paper presents a comprehensive survey of hypothesis generation with LLMs by (i) reviewing existing methods, from simple prompting techniques to more complex frameworks, and proposing a taxonomy that categorizes these approaches; (ii) analyzing techniques for improving hypothesis quality, such as novelty boosting and structured reasoning; (iii) providing an overview of evaluation strategies; and (iv) discussing key challenges and future directions, including multimodal integration and human-AI collaboration. Our survey aims to serve as a reference for researchers exploring LLMs for hypothesis generation.

Text clustering holds significant value across various domains due to its ability to identify patterns and group related information. Current approaches which rely heavily on a computed similarity measure between documents are often limited in accuracy and interpretability. We present a novel approach to the problem based on a set of evolved search queries. Clusters are formed as the set of documents matched by a single search query in the set of queries. The queries are optimized to maximize the number of documents returned and to minimize the overlap between clusters (documents returned by more than one query). Where queries contain more than one word they are interpreted disjunctively. We have found it useful to assign one word to be the root and constrain the query construction such that the set of documents returned by any additional query words intersect with the set returned by the root word. Not all documents in a collection are returned by any of the search queries in a set, so once the search query evolution is completed a second stage is performed whereby a KNN algorithm is applied to assign all unassigned documents to their nearest cluster. We describe the method and present results using 8 text datasets comparing effectiveness with well-known existing algorithms. We note that as well as achieving the highest accuracy on these datasets the search query format provides the qualitative benefits of being interpretable and modifiable whilst providing a causal explanation of cluster construction.

Sequential recommendation is an advanced recommendation technique that utilizes the sequence of user behaviors to generate personalized suggestions by modeling the temporal dependencies and patterns in user preferences. However, it requires a server to centrally collect users' data, which poses a threat to the data privacy of different users. In recent years, federated learning has emerged as a distributed architecture that allows participants to train a global model while keeping their private data locally. This survey pioneers Federated Sequential Recommendation (FedSR), where each user joins as a participant in federated training to achieve a recommendation service that balances data privacy and model performance. We begin with an introduction to the background and unique challenges of FedSR. Then, we review existing solutions from two levels, each of which includes two specific techniques. Additionally, we discuss the critical challenges and future research directions in FedSR.

Spatio-temporal point processes (STPPs) model discrete events distributed in time and space, with important applications in areas such as criminology, seismology, epidemiology, and social networks. Traditional models often rely on parametric kernels, limiting their ability to capture heterogeneous, nonstationary dynamics. Recent innovations integrate deep neural architectures -- either by modeling the conditional intensity function directly or by learning flexible, data-driven influence kernels, substantially broadening their expressive power. This article reviews the development of the deep influence kernel approach, which enjoys statistical explainability, since the influence kernel remains in the model to capture the spatiotemporal propagation of event influence and its impact on future events, while also possessing strong expressive power, thereby benefiting from both worlds. We explain the main components in developing deep kernel point processes, leveraging tools such as functional basis decomposition and graph neural networks to encode complex spatial or network structures, as well as estimation using both likelihood-based and likelihood-free methods, and address computational scalability for large-scale data. We also discuss the theoretical foundation of kernel identifiability. Simulated and real-data examples highlight applications to crime analysis, earthquake aftershock prediction, and sepsis prediction modeling, and we conclude by discussing promising directions for the field.

Computational phenotyping is essential for biomedical research but often requires significant time and resources, especially since traditional methods typically involve extensive manual data review. While machine learning and natural language processing advancements have helped, further improvements are needed. Few studies have explored using Large Language Models (LLMs) for these tasks despite known advantages of LLMs for text-based tasks. T o facilitate further research in this area, we developed an evaluation framework, Evaluation of PHEnotyping for Observational Health Data (PHEONA), that outlines context-specific considerations. W e applied and demonstrated PHEONA on concept classification, a specific task within a broader phenotyping process for Acute Respiratory Failure (ARF) respiratory support therapies. From the sample concepts tested, we achieved high classification accuracy, suggesting the potential for LLM-based methods to improve computational phenotyping processes.

Given two boundary distributions, the Schr\"odinger Bridge (SB) problem seeks the ``most likely`` random evolution between them with respect to a reference process. It has revealed rich connections to recent machine learning methods for generative modeling and distribution matching. While these methods perform well in Euclidean domains, they are not directly applicable to topological domains such as graphs and simplicial complexes, which are crucial for data defined over network entities, such as node signals and edge flows. In this work, we propose the Topological Schr\"odinger Bridge problem (TSBP) for matching signal distributions on a topological domain. We set the reference process to follow some linear tractable topology-aware stochastic dynamics such as topological heat diffusion. For the case of Gaussian boundary distributions, we derive a closed-form topological SB (TSB) in terms of its time-marginal and stochastic differential. In the general case, leveraging the well-known result, we show that the optimal process follows the forward-backward topological dynamics governed by some unknowns. Building on these results, we develop TSB-based models for matching topological signals by parameterizing the unknowns in the optimal process as (topological) neural networks and learning them through likelihood training. We validate the theoretical results and demonstrate the practical applications of TSB-based models on both synthetic and real-world networks, emphasizing the role of topology. Additionally, we discuss the connections of TSB-based models to other emerging models, and outline future directions for topological signal matching.

The Model Context Protocol (MCP) is a standardized interface designed to enable seamless interaction between AI models and external tools and resources, breaking down data silos and facilitating interoperability across diverse systems. This paper provides a comprehensive overview of MCP, focusing on its core components, workflow, and the lifecycle of MCP servers, which consists of three key phases: creation, operation, and update. We analyze the security and privacy risks associated with each phase and propose strategies to mitigate potential threats. The paper also examines the current MCP landscape, including its adoption by industry leaders and various use cases, as well as the tools and platforms supporting its integration. We explore future directions for MCP, highlighting the challenges and opportunities that will influence its adoption and evolution within the broader AI ecosystem. Finally, we offer recommendations for MCP stakeholders to ensure its secure and sustainable development as the AI landscape continues to evolve.