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Distributed Control of Microscopic Robots in Biomedical Applications

arXiv.org Artificial Intelligence

Current developments in molecular electronics, motors and chemical sensors could enable constructing large numbers of devices able to sense, compute and act in micron-scale environments. Such microscopic machines, of sizes comparable to bacteria, could simultaneously monitor entire populations of cells individually in vivo. This paper reviews plausible capabilities for microscopic robots and the physical constraints due to operation in fluids at low Reynolds number, diffusion-limited sensing and thermal noise from Brownian motion. Simple distributed controls are then presented in the context of prototypical biomedical tasks, which require control decisions on millisecond time scales. The resulting behaviors illustrate trade-offs among speed, accuracy and resource use. A specific example is monitoring for patterns of chemicals in a flowing fluid released at chemically distinctive sites. Information collected from a large number of such devices allows estimating properties of cell-sized chemical sources in a macroscopic volume. The microscopic devices moving with the fluid flow in small blood vessels can detect chemicals released by tissues in response to localized injury or infection. We find the devices can readily discriminate a single cell-sized chemical source from the background chemical concentration, providing high-resolution sensing in both time and space. By contrast, such a source would be difficult to distinguish from background when diluted throughout the blood volume as obtained with a blood sample.


Properties and Applications of Programs with Monotone and Convex Constraints

Journal of Artificial Intelligence Research

We study properties of programs with monotone and convex constraints. We extend to these formalisms concepts and results from normal logic programming. They include the notions of strong and uniform equivalence with their characterizations, tight programs and Fages Lemma, program completion and loop formulas. Our results provide an abstract account of properties of some recent extensions of logic programming with aggregates, especially the formalism of lparse programs. They imply a method to compute stable models of lparse programs by means of off-the-shelf solvers of pseudo-boolean constraints, which is often much faster than the smodels system.


The Reaction RuleML Classification of the Event / Action / State Processing and Reasoning Space

arXiv.org Artificial Intelligence

Reaction RuleML is a general, practical, compact and user-friendly XML-serialized language for the family of reaction rules. In this white paper we give a review of the history of event / action /state processing and reaction rule approaches and systems in different domains, define basic concepts and give a classification of the event, action, state processing and reasoning space as well as a discussion of relevant / related work


Efficient constraint propagation engines

arXiv.org Artificial Intelligence

This paper presents a model and implementation techniques for speeding up constraint propagation. Three fundamental approaches to improving constraint propagation based on propagators as implementations of constraints are explored: keeping track of which propagators are at fixpoint, choosing which propagator to apply next, and how to combine several propagators for the same constraint. We show how idempotence reasoning and events help track fixpoints more accurately. We improve these methods by using them dynamically (taking into account current domains to improve accuracy). We define priority-based approaches to choosing a next propagator and show that dynamic priorities can improve propagation. We illustrate that the use of multiple propagators for the same constraint can be advantageous with priorities, and introduce staged propagators that combine the effects of multiple propagators with priorities for greater efficiency.


Modelling Mixed Discrete-Continuous Domains for Planning

Journal of Artificial Intelligence Research

In this paper we present pddl+, a planning domain description language for modelling mixed discrete-continuous planning domains. We describe the syntax and modelling style of pddl+, showing that the language makes convenient the modelling of complex time-dependent effects. We provide a formal semantics for pddl+ by mapping planning instances into constructs of hybrid automata. Using the syntax of HAs as our semantic model we construct a semantic mapping to labelled transition systems to complete the formal interpretation of pddl+ planning instances. An advantage of building a mapping from pddl+ to HA theory is that it forms a bridge between the Planning and Real Time Systems research communities. One consequence is that we can expect to make use of some of the theoretical properties of HAs. For example, for a restricted class of HAs the Reachability problem (which is equivalent to Plan Existence) is decidable. pddl+ provides an alternative to the continuous durative action model of pddl2.1, adding a more flexible and robust model of time-dependent behaviour.


Active Learning with Multiple Views

Journal of Artificial Intelligence Research

Active learners alleviate the burden of labeling large amounts of data by detecting and asking the user to label only the most informative examples in the domain. We focus here on active learning for multi-view domains, in which there are several disjoint subsets of features (views), each of which is sufficient to learn the target concept. In this paper we make several contributions. First, we introduce Co-Testing, which is the first approach to multi-view active learning. Second, we extend the multi-view learning framework by also exploiting weak views, which are adequate only for learning a concept that is more general/specific than the target concept. Finally, we empirically show that Co-Testing outperforms existing active learners on a variety of real world domains such as wrapper induction, Web page classification, advertisement removal, and discourse tree parsing.


Decentralized Failure Diagnosis of Stochastic Discrete Event Systems

arXiv.org Artificial Intelligence

Recently, the diagnosability of {\it stochastic discrete event systems} (SDESs) was investigated in the literature, and, the failure diagnosis considered was {\it centralized}. In this paper, we propose an approach to {\it decentralized} failure diagnosis of SDESs, where the stochastic system uses multiple local diagnosers to detect failures and each local diagnoser possesses its own information. In a way, the centralized failure diagnosis of SDESs can be viewed as a special case of the decentralized failure diagnosis presented in this paper with only one projection. The main contributions are as follows: (1) We formalize the notion of codiagnosability for stochastic automata, which means that a failure can be detected by at least one local stochastic diagnoser within a finite delay. (2) We construct a codiagnoser from a given stochastic automaton with multiple projections, and the codiagnoser associated with the local diagnosers is used to test codiagnosability condition of SDESs. (3) We deal with a number of basic properties of the codiagnoser. In particular, a necessary and sufficient condition for the codiagnosability of SDESs is presented. (4) We give a computing method in detail to check whether codiagnosability is violated. And (5) some examples are described to illustrate the applications of the codiagnosability and its computing method.


Solving Factored MDPs with Hybrid State and Action Variables

Journal of Artificial Intelligence Research

Efficient representations and solutions for large decision problems with continuous and discrete variables are among the most important challenges faced by the designers of automated decision support systems. In this paper, we describe a novel hybrid factored Markov decision process (MDP) model that allows for a compact representation of these problems, and a new hybrid approximate linear programming (HALP) framework that permits their efficient solutions. The central idea of HALP is to approximate the optimal value function by a linear combination of basis functions and optimize its weights by linear programming. We analyze both theoretical and computational aspects of this approach, and demonstrate its scale-up potential on several hybrid optimization problems.


A Comparison of Different Machine Transliteration Models

Journal of Artificial Intelligence Research

Machine transliteration is a method for automatically converting words in one language into phonetically equivalent ones in another language. Machine transliteration plays an important role in natural language applications such as information retrieval and machine translation, especially for handling proper nouns and technical terms. Four machine transliteration models -- grapheme-based transliteration model, phoneme-based transliteration model, hybrid transliteration model, and correspondence-based transliteration model -- have been proposed by several researchers. To date, however, there has been little research on a framework in which multiple transliteration models can operate simultaneously. Furthermore, there has been no comparison of the four models within the same framework and using the same data. We addressed these problems by 1) modeling the four models within the same framework, 2) comparing them under the same conditions, and 3) developing a way to improve machine transliteration through this comparison. Our comparison showed that the hybrid and correspondence-based models were the most effective and that the four models can be used in a complementary manner to improve machine transliteration performance.


Language, logic and ontology: uncovering the structure of commonsense knowledge

arXiv.org Artificial Intelligence

In Logic and Ontology Cocchiarella (2001) convincingly argues for a view of "logic as a language" in contrast with the (now dominant) view of "logic as a calculus". In the latter, logic is viewed as an "abstract calculus that has no content of its own, and which depends on set theory as a background framework by which such a calculus might be syntactically described and semantically interpreted." In the view of "logic as a language", however, logic has content, and "ontological content in particular." Moreover, and according to Cocchiarella, a logic with ontological content necessitates the use of type theory (and predication), as opposed to set theory (and set membership), as the background framework. An obvious question that immediately comes to mind here is the following: what exactly is the nature of this strongly-typed ontological structure that will form the background framework for a new logic that has content?