We propose a general matrix-valued multiple kernel learning framework for high-dimensional nonlinear multivariate regression problems. This framework allows a broad class of mixed norm regularizers, including those that induce sparsity, to be imposed on a dictionary of vector-valued Reproducing Kernel Hilbert Spaces. We develop a highly scalable and eigendecomposition-free algorithm that orchestrates two inexact solvers for simultaneously learning both the input and output components of separable matrix-valued kernels. As a key application enabled by our framework, we show how high-dimensional causal inference tasks can be naturally cast as sparse function estimation problems, leading to novel nonlinear extensions of a class of Graphical Granger Causality techniques. Our algorithmic developments and extensive empirical studies are complemented by theoretical analyses in terms of Rademacher generalization bounds.

Introduction. Case Based Reasoning (CBR) is an emerg- ing decision making paradigm in medical research where new cases are solved relying on previously solved similar cases. Usually, a database of solved cases is provided, and every case is described through a set of attributes (inputs) and a label (output). Extracting useful information from this database can help the CBR system providing more reliable results on the yet to be solved cases. Objective. For that purpose we suggest a general frame- work where a CBR system, viz. K-Nearest Neighbor (K-NN) algorithm, is combined with various information obtained from a Logistic Regression (LR) model. Methods. LR is applied, on the case database, to assign weights to the attributes as well as the solved cases. Thus, five possible decision making systems based on K-NN and/or LR were identified: a standalone K-NN, a standalone LR and three soft K-NN algorithms that rely on the weights based on the results of the LR. The evaluation of the described approaches is performed in the field of renal transplant access waiting list. Results and conclusion. The results show that our suggested approach, where the K-NN algorithm relies on both weighted attributes and cases, can efficiently deal with non relevant attributes, whereas the four other approaches suffer from this kind of noisy setups. The robustness of this approach suggests interesting perspectives for medical problem solving tools using CBR methodology.

Information-Geometric Optimization (IGO) is a unified framework of stochastic algorithms for optimization problems. Given a family of probability distributions, IGO turns the original optimization problem into a new maximization problem on the parameter space of the probability distributions. IGO updates the parameter of the probability distribution along the natural gradient, taken with respect to the Fisher metric on the parameter manifold, aiming at maximizing an adaptive transform of the objective function. IGO recovers several known algorithms as particular instances: for the family of Bernoulli distributions IGO recovers PBIL, for the family of Gaussian distributions the pure rank-mu CMA-ES update is recovered, and for exponential families in expectation parametrization the cross-entropy/ML method is recovered. This article provides a theoretical justification for the IGO framework, by proving that any step size not greater than 1 guarantees monotone improvement over the course of optimization, in terms of q-quantile values of the objective function f. The range of admissible step sizes is independent of f and its domain. We extend the result to cover the case of different step sizes for blocks of the parameters in the IGO algorithm. Moreover, we prove that expected fitness improves over time when fitness-proportional selection is applied, in which case the RPP algorithm is recovered.

This paper describes a normative system design that incorporates diagnosis, dynamic evolution, decision making, and information gathering. A single influence diagram demonstrates the design's coherence, yet each activity is more effectively modeled and evaluated separately. Application to offshore oil platforms illustrates the design. For this application, the normative system is embedded in a real-time expert system.

In previous work we developed a method of learning Bayesian Network models from raw data. This method relies on the well known minimal description length (MDL) principle. The MDL principle is particularly well suited to this task as it allows us to tradeoff, in a principled way, the accuracy of the learned network against its practical usefulness. In this paper we present some new results that have arisen from our work. In particular, we present a new local way of computing the description length. This allows us to make significant improvements in our search algorithm. In addition, we modify our algorithm so that it can take into account partial domain information that might be provided by a domain expert. The local computation of description length also opens the door for local refinement of an existent network. The feasibility of our approach is demonstrated by experiments involving networks of a practical size.

To determine the value of perfect information in an influence diagram, one needs first to modify the diagram to reflect the change in information availability, and then to compute the optimal expected values of both the original diagram and the modified diagram. The value of perfect information is the difference between the two optimal expected values. This paper is about how to speed up the computation of the optimal expected value of the modified diagram by making use of the intermediate computation results obtained when computing the optimal expected value of the original diagram.

We present an approach to propagation-based SAT encoding of combinatorial problems, Boolean equi-propagation, where constraints are modeled as Boolean functions which propagate information about equalities between Boolean literals. This information is then applied to simplify the CNF encoding of the constraints. A key factor is that considering only a small fragment of a constraint model at one time enables us to apply stronger, and even complete, reasoning to detect equivalent literals in that fragment. Once detected, equivalences apply to simplify the entire constraint model and facilitate further reasoning on other fragments. Equi-propagation in combination with partial evaluation and constraint simplification provide the foundation for a powerful approach to SAT-based finite domain constraint solving. We introduce a tool called BEE (Ben-Gurion Equi-propagation Encoder) based on these ideas and demonstrate for a variety of benchmarks that our approach leads to a considerable reduction in the size of CNF encodings and subsequent speed-ups in SAT solving times.

In order to find a causal explanation for data presented in the form of covariance and concentration matrices it is necessary to decide if the graph formed by such associations is a projection of a directed acyclic graph (dag). We show that the general problem of deciding whether such a dag exists is NP-complete.

In this paper, we present a Bayesian channel estimation algorithm for multicarrier receivers based on pilot symbol observations. The inherent sparse nature of wireless multipath channels is exploited by modeling the prior distribution of multipath components' gains with a hierarchical representation of the Bessel K probability density function; a highly efficient, fast iterative Bayesian inference method is then applied to the proposed model. The resulting estimator outperforms other state-of-the-art Bayesian and non-Bayesian estimators, either by yielding lower mean squared estimation error or by attaining the same accuracy with improved convergence rate, as shown in our numerical evaluation.

In this paper, we present a decision support system based on belief functions and the pignistic transformation. The system is an integration of an evidential system for belief function propagation and a valuation-based system for Bayesian decision analysis. The two subsystems are connected through the pignistic transformation. The system takes as inputs the user's "gut feelings" about a situation and suggests what, if any, are to be tested and in what order, and it does so with a user friendly interface.