Despite the advances in medicine, cancer has remained a formidable challenge. Particularly in the case of pancreatic tumors, characterized by their diversity and late diagnosis, early detection poses a significant challenge crucial for effective treatment. The advancement of deep learning techniques, particularly supervised algorithms, has significantly propelled pancreatic tumor detection in the medical field. However, supervised deep learning approaches necessitate extensive labeled medical images for training, yet acquiring such annotations is both limited and costly. Conversely, weakly supervised anomaly detection methods, requiring only image-level annotations, have garnered interest. Existing methodologies predominantly hinge on generative adversarial networks (GANs) or autoencoder models, which can pose complexity in training and, these models may face difficulties in accurately preserving fine image details. This research presents a novel approach to pancreatic tumor detection, employing weak supervision anomaly detection through denoising diffusion algorithms. By incorporating a deterministic iterative process of adding and removing noise along with classifier guidance, the method enables seamless translation of images between diseased and healthy subjects, resulting in detailed anomaly maps without requiring complex training protocols and segmentation masks. This study explores denoising diffusion models as a recent advancement over traditional generative models like GANs, contributing to the field of pancreatic tumor detection. Recognizing the low survival rates of pancreatic cancer, this study emphasizes the need for continued research to leverage diffusion models' efficiency in medical segmentation tasks.

To enable Large Language Models (LLMs) to function as conscious agents with generalizable reasoning capabilities, it is crucial that they possess the reasoning ability to comprehend situational changes (transitions) in distribution triggered by environmental factors or actions from other agents. Despite its fundamental significance, this ability remains underexplored due to the complexity of modeling infinite possible changes in an event and their associated distributions, coupled with the lack of benchmark data with situational transitions. Addressing these gaps, we propose a novel formulation of reasoning with distributional changes as a three-step discriminative process, termed as MetAphysical ReaSoning. We then introduce the first-ever benchmark, MARS, comprising three tasks corresponding to each step. These tasks systematically assess LLMs' capabilities in reasoning the plausibility of (i) changes in actions, (ii) states caused by changed actions, and (iii) situational transitions driven by changes in action. Extensive evaluations with 20 (L)LMs of varying sizes and methods indicate that all three tasks in this process pose significant challenges, even for state-of-the-art LLMs and LMs after fine-tuning. Further analyses reveal potential causes for the underperformance of LLMs and demonstrate that pre-training them on large-scale conceptualization taxonomies can potentially enhance their metaphysical reasoning capabilities. Our data and models are publicly accessible at https://github.com/HKUST-KnowComp/MARS.

Large-language Models (LLMs) have been extremely successful at tasks like complex dialogue understanding, reasoning and coding due to their emergent abilities. These emergent abilities have been extended with multi-modality to include image, audio, and video capabilities. Recommender systems, on the other hand, have been critical for information seeking and item discovery needs. Recently, there have been attempts to apply LLMs for recommendations. One difficulty of current attempts is that the underlying LLM is usually not trained on the recommender system data, which largely contains user interaction signals and is often not publicly available. Another difficulty is user interaction signals often have a different pattern from natural language text, and it is currently unclear if the LLM training setup can learn more non-trivial knowledge from interaction signals compared with traditional recommender system methods. Finally, it is difficult to train multiple LLMs for different use-cases, and to retain the original language and reasoning abilities when learning from recommender system data. To address these three limitations, we propose an Item-Language Model (ILM), which is composed of an item encoder to produce text-aligned item representations that encode user interaction signals, and a frozen LLM that can understand those item representations with preserved pretrained knowledge. We conduct extensive experiments which demonstrate both the importance of the language-alignment and of user interaction knowledge in the item encoder.

While Multi-view Graph Neural Networks (MVGNNs) excel at leveraging diverse modalities for learning object representation, existing methods assume identical local topology structures across modalities that overlook real-world discrepancies. This leads MVGNNs straggles in modality fusion and representations denoising. To address these issues, we propose adaptive modality-wise structure learning (AMoSL). To enable efficient end-to-end training, we employ an efficient solution for the resulting complex bilevel optimization problem. The effectiveness of AMoSL is demonstrated by its ability to train more accurate graph classifiers on six benchmark datasets. NTRODUCTION A large amount of data networks exhibits a unique structure known as graph-structured data. Irregular, non-Euclidean data characterize this data type and are frequently found in areas such as recommendation systems [1], social media networks [2], knowledge graphs [3], and molecular structures [4]. The analysis of graph-structured data has garnered substantial attention for its inherent inductive and transductive properties, which enable relational reasoning among entities (nodes) and their connections (edges). Graph Neural Networks (GNNs), through a series of advancements [5][6][7][8][9][10][11][12][13], have shown promising improvement in studying graph-structured data to conduct various downstream graph-related tasks.

The Generative Flow Network (GFlowNet) is a probabilistic framework in which an agent learns a stochastic policy and flow functions to sample objects with probability proportional to an unnormalized reward function. GFlowNets share a strong resemblance to reinforcement learning (RL), that typically aims to maximize reward, due to their sequential decision-making processes. Recent works have studied connections between GFlowNets and maximum entropy (MaxEnt) RL, which modifies the standard objective of RL agents by learning an entropy-regularized objective. However, a critical theoretical gap persists: despite the apparent similarities in their sequential decision-making nature, a direct link between GFlowNets and standard RL has yet to be discovered, while bridging this gap could further unlock the potential of both fields. In this paper, we establish a new connection between GFlowNets and policy evaluation for a uniform policy. Surprisingly, we find that the resulting value function for the uniform policy has a close relationship to the flows in GFlowNets. Leveraging these insights, we further propose a novel rectified policy evaluation (RPE) algorithm, which achieves the same reward-matching effect as GFlowNets, offering a new perspective. We compare RPE, MaxEnt RL, and GFlowNets in a number of benchmarks, and show that RPE achieves competitive results compared to previous approaches. This work sheds light on the previously unexplored connection between (non-MaxEnt) RL and GFlowNets, potentially opening new avenues for future research in both fields.

Generative models guided by text prompts are increasingly becoming more popular. However, no text-to-MIDI models currently exist, mostly due to the lack of a captioned MIDI dataset. This work aims to enable research that combines LLMs with symbolic music by presenting the first large-scale MIDI dataset with text captions that is openly available: MidiCaps. MIDI (Musical Instrument Digital Interface) files are a widely used format for encoding musical information. Their structured format captures the nuances of musical composition and has practical applications by music producers, composers, musicologists, as well as performers. Inspired by recent advancements in captioning techniques applied to various domains, we present a large-scale curated dataset of over 168k MIDI files accompanied by textual descriptions. Each MIDI caption succinctly describes the musical content, encompassing tempo, chord progression, time signature, instruments present, genre and mood; thereby facilitating multi-modal exploration and analysis. The dataset contains a mix of various genres, styles, and complexities, offering a rich source for training and evaluating models for tasks such as music information retrieval, music understanding and cross-modal translation. We provide detailed statistics about the dataset and have assessed the quality of the captions in an extensive listening study. We anticipate that this resource will stimulate further research in the intersection of music and natural language processing, fostering advancements in both fields.

Educational resource understanding is vital to online learning platforms, which have demonstrated growing applications recently. However, researchers and developers always struggle with using existing general natural language toolkits or domain-specific models. The issue raises a need to develop an effective and easy-to-use one that benefits AI education-related research and applications. To bridge this gap, we present a unified, modularized, and extensive library, EduNLP, focusing on educational resource understanding. In the library, we decouple the whole workflow to four key modules with consistent interfaces including data configuration, processing, model implementation, and model evaluation. We also provide a configurable pipeline to unify the data usage and model usage in standard ways, where users can customize their own needs. For the current version, we primarily provide 10 typical models from four categories, and 5 common downstream-evaluation tasks in the education domain on 8 subjects for users' usage. The project is released at: https://github.com/bigdata-ustc/EduNLP.

Large language models (LLMs) like ChatGPT show excellent capabilities in various natural language processing tasks, especially for text generation. The effectiveness of LLMs in summarizing radiology report impressions remains unclear. In this study, we explore the capability of eight LLMs on the radiology report impression summarization. Three types of radiology reports, i.e., CT, PET-CT, and Ultrasound reports, are collected from Peking University Cancer Hospital and Institute. We use the report findings to construct the zero-shot, one-shot, and three-shot prompts with complete example reports to generate the impressions. Besides the automatic quantitative evaluation metrics, we define five human evaluation metrics, i.e., completeness, correctness, conciseness, verisimilitude, and replaceability, to evaluate the semantics of the generated impressions. Two thoracic surgeons (ZSY and LB) and one radiologist (LQ) compare the generated impressions with the reference impressions and score each impression under the five human evaluation metrics. Experimental results show that there is a gap between the generated impressions and reference impressions. Although the LLMs achieve comparable performance in completeness and correctness, the conciseness and verisimilitude scores are not very high. Using few-shot prompts can improve the LLMs' performance in conciseness and verisimilitude, but the clinicians still think the LLMs can not replace the radiologists in summarizing the radiology impressions.

Telling stories is an integral part of human communication which can evoke emotions and influence the affective states of the audience. Automatically modeling emotional trajectories in stories has thus attracted considerable scholarly interest. However, as most existing works have been limited to unsupervised dictionary-based approaches, there is no benchmark for this task. We address this gap by introducing continuous valence and arousal labels for an existing dataset of children's stories originally annotated with discrete emotion categories. We collect additional annotations for this data and map the categorical labels to the continuous valence and arousal space. For predicting the thus obtained emotionality signals, we fine-tune a DeBERTa model and improve upon this baseline via a weakly supervised learning approach. The best configuration achieves a Concordance Correlation Coefficient (CCC) of $.8221$ for valence and $.7125$ for arousal on the test set, demonstrating the efficacy of our proposed approach. A detailed analysis shows the extent to which the results vary depending on factors such as the author, the individual story, or the section within the story. In addition, we uncover the weaknesses of our approach by investigating examples that prove to be difficult to predict.

The Univer sity of Texas at Arlington, 2015 Sup ervising Professor: Michael Manry There is always an ambiguity in deciding the number of learning factors that is really required for training a Multi - Layer Perceptron. This thesis solves this problem by introducing a new method of adaptively changing the number of learning factors computed based on the error change created per multiply. A new method is introduced for computing learning factors for weights grouped based on the curvature of the objective function. A method for linearly compressing large ill - conditioned Newton's Hessian matrices to smaller well - conditioned ones is shown. This thesis also shows that the proposed training algorithm adapts itself between two other algorithms in order to produce a better error decrease per multiply. The performanc e of the proposed algorithm is shown to be better than OWO - MOLF and Levenberg Marquardt for most of the data sets.