The diagnostic accuracy and subjectivity of existing Knee Osteoarthritis (OA) ordinal grading systems has been a subject of on-going debate and concern. Existing automated solutions are trained to emulate these imperfect systems, whilst also being reliant on large annotated databases for fully-supervised training. This work proposes a three stage approach for automated continuous grading of knee OA that is built upon the principles of Anomaly Detection (AD); learning a robust representation of healthy knee X-rays and grading disease severity based on its distance to the centre of normality. In the first stage, SS-FewSOME is proposed, a self-supervised AD technique that learns the 'normal' representation, requiring only examples of healthy subjects and <3% of the labels that existing methods require. In the second stage, this model is used to pseudo label a subset of unlabelled data as 'normal' or 'anomalous', followed by denoising of pseudo labels with CLIP. The final stage involves retraining on labelled and pseudo labelled data using the proposed Dual Centre Representation Learning (DCRL) which learns the centres of two representation spaces; normal and anomalous. Disease severity is then graded based on the distance to the learned centres. The proposed methodology outperforms existing techniques by margins of up to 24% in terms of OA detection and the disease severity scores correlate with the Kellgren-Lawrence grading system at the same level as human expert performance. Code available at https://github.com/niamhbelton/SS-FewSOME_Disease_Severity_Knee_Osteoarthritis.

With the advanced vision capabilities of GPT-4o and Gemini Flash, an important question arises regarding the accuracy of these functionalities in practical business applications. Our assumption was that multimodal models are good at reading and summarizing charts. When given an image of a slide deck, they do a good job of summarizing key insights from it, often including relevant data points. Existing research into this question has evaluated the efficacy of LLM's when parsing tables [3], concluding that the LLMs were highly sensitive to input prompts which drive performance. Other works also evaluate LLMs ability to reason and read mathematical graphs [2] and find that GPT models outperform alternatives. This paper aims to explore whether multimodal models perform well on a variant of this skill - answering straightforward questions that require the models to pick out a number from a slide deck.

The rapid growth in the use of Large Language Models (LLMs) and AI Agents as part of software development and deployment is revolutionizing the information technology landscape. While code generation receives significant attention, a higher-impact application lies in using AI agents for operational resilience of cloud services, which currently require significant human effort and domain knowledge. There is a growing interest in AI for IT Operations (AIOps) which aims to automate complex operational tasks, like fault localization and root cause analysis, thereby reducing human intervention and customer impact. However, achieving the vision of autonomous and self-healing clouds though AIOps is hampered by the lack of standardized frameworks for building, evaluating, and improving AIOps agents. This vision paper lays the groundwork for such a framework by first framing the requirements and then discussing design decisions that satisfy them. We also propose AIOpsLab, a prototype implementation leveraging agent-cloud-interface that orchestrates an application, injects real-time faults using chaos engineering, and interfaces with an agent to localize and resolve the faults. We report promising results and lay the groundwork to build a modular and robust framework for building, evaluating, and improving agents for autonomous clouds.

In the field of emotion analysis, much NLP research focuses on identifying a limited number of discrete emotion categories, often applied across languages. These basic sets, however, are rarely designed with textual data in mind, and culture, language, and dialect can influence how particular emotions are interpreted. In this work, we broaden our scope to a practically unbounded set of \textit{affective states}, which includes any terms that humans use to describe their experiences of feeling. We collect and publish MASIVE, a dataset of Reddit posts in English and Spanish containing over 1,000 unique affective states each. We then define the new problem of \textit{affective state identification} for language generation models framed as a masked span prediction task. On this task, we find that smaller finetuned multilingual models outperform much larger LLMs, even on region-specific Spanish affective states. Additionally, we show that pretraining on MASIVE improves model performance on existing emotion benchmarks. Finally, through machine translation experiments, we find that native speaker-written data is vital to good performance on this task.

We propose a comprehensive approach to increase the reliability and resilience of future power grids rich in distributed energy resources. Our distributed scheme combines federated learning-based attack detection with a local electricity market-based attack mitigation method. We validate the scheme by applying it to a real-world distribution grid rich in solar PV. Simulation results demonstrate that the approach is feasible and can successfully mitigate the grid impacts of cyber-physical attacks.

Stop location detection, within human mobility studies, has an impacts in multiple fields including urban planning, transport network design, epidemiological modeling, and socio-economic segregation analysis. However, it remains a challenging task because classical density clustering algorithms often struggle with noisy or incomplete GPS datasets. This study investigates the application of classification algorithms to enhance density-based methods for stop identification. Our approach incorporates multiple features, including individual routine behavior across various time scales and local characteristics of individual GPS points. The dataset comprises privacy-preserving and anonymized GPS points previously labeled as stops by a sequence-oriented, density-dependent algorithm. We simulated data gaps by removing point density from select stops to assess performance under sparse data conditions. The model classifies individual GPS points within trajectories as potential stops or non-stops. Given the highly imbalanced nature of the dataset, we prioritized recall over precision in performance evaluation. Results indicate that this method detects most stops, even in the presence of spatio-temporal gaps and that points classified as false positives often correspond to recurring locations for devices, typically near previous stops. While this research contributes to mobility analysis techniques, significant challenges persist. The lack of ground truth data limits definitive conclusions about the algorithm's accuracy. Further research is needed to validate the method across diverse datasets and to incorporate collective behavior inputs.

Generating as diverse molecules as possible with desired properties is crucial for drug discovery research, which invokes many approaches based on deep generative models today. Despite recent advancements in these models, particularly in variational autoencoders (VAEs), generative adversarial networks (GANs), Transformers, and diffusion models, a significant challenge known as \textit{the sample bias problem} remains. This problem occurs when generated molecules targeting the same protein tend to be structurally similar, reducing the diversity of generation. To address this, we propose leveraging multi-hop relationships among proteins and compounds. Our model, Repurformer, integrates bi-directional pretraining with Fast Fourier Transform (FFT) and low-pass filtering (LPF) to capture complex interactions and generate diverse molecules. A series of experiments on BindingDB dataset confirm that Repurformer successfully creates substitutes for anchor compounds that resemble positive compounds, increasing diversity between the anchor and generated compounds.

We introduce GoldFinch, a hybrid Linear Attention/Transformer sequence model that uses a new technique to efficiently generate a highly compressed and reusable KV-Cache in linear time and space with respect to sequence length. GoldFinch stacks our new GOLD transformer on top of an enhanced version of the Finch (RWKV-6) architecture. We train up to 1.5B parameter class models of the Finch, Llama, and GoldFinch architectures, and find dramatically improved modeling performance relative to both Finch and Llama. Our cache size savings increase linearly with model layer count, ranging from 756-2550 times smaller than the traditional transformer cache for common sizes, enabling inference of extremely large context lengths even on limited hardware. Although autoregressive generation has O(n) time complexity per token because of attention, pre-fill computation of the entire initial cache state for a submitted context costs only O(1) time per token due to the use of a recurrent neural network (RNN) to generate this cache. We release our trained weights and training code under the Apache 2.0 license for community use.

Farmers face various challenges when it comes to identifying diseases in rice leaves during their early stages of growth, which is a major reason for poor produce. Therefore, early and accurate disease identification is important in agriculture to avoid crop loss and improve cultivation. In this research, we propose a novel hybrid deep learning (DL) classifier designed by extending the Squeeze-and-Excitation network architecture with a channel attention mechanism and the Swish ReLU activation function. The channel attention mechanism in our proposed model identifies the most important feature channels required for classification during feature extraction and selection. The dying ReLU problem is mitigated by utilizing the Swish ReLU activation function, and the Squeeze-andExcitation blocks improve information propagation and cross-channel interaction. Upon evaluation, our model achieved a high F1-score of 99.76% and an accuracy of 99.74%, surpassing the performance of existing models. These outcomes demonstrate the potential of state-of-the-art DL techniques in agriculture, contributing to the advancement of more efficient and reliable disease detection systems.

We present an approach for generating differentially private synthetic text using large language models (LLMs), via private prediction. In the private prediction framework, we only require the output synthetic data to satisfy differential privacy guarantees. This is in contrast to approaches that train a generative model on potentially sensitive user-supplied source data and seek to ensure the model itself is safe to release. We prompt a pretrained LLM with source data, but ensure that next-token predictions are made with differential privacy guarantees. Previous work in this paradigm reported generating a small number of examples (<10) at reasonable privacy levels, an amount of data that is useful only for downstream in-context learning or prompting. In contrast, we make changes that allow us to generate thousands of high-quality synthetic data points, greatly expanding the set of potential applications. Our improvements come from an improved privacy analysis and a better private selection mechanism, which makes use of the equivalence between the softmax layer for sampling tokens in LLMs and the exponential mechanism. Furthermore, we introduce a novel use of public predictions via the sparse vector technique, in which we do not pay privacy costs for tokens that are predictable without sensitive data; we find this to be particularly effective for structured data.