Many large language models (LLMs) for medicine have largely been evaluated on short texts, and their ability to handle longer sequences such as a complete electronic health record (EHR) has not been systematically explored. Assessing these models on long sequences is crucial since prior work in the general domain has demonstrated performance degradation of LLMs on longer texts. Motivated by this, we introduce LongBoX, a collection of seven medical datasets in text-to-text format, designed to investigate model performance on long sequences. Preliminary experiments reveal that both medical LLMs (e.g., BioGPT) and strong general domain LLMs (e.g., FLAN-T5) struggle on this benchmark. We further evaluate two techniques designed for long-sequence handling: (i) local-global attention, and (ii) Fusion-in-Decoder (FiD). Our results demonstrate mixed results with long-sequence handling - while scores on some datasets increase, there is substantial room for improvement. We hope that LongBoX facilitates the development of more effective long-sequence techniques for the medical domain. Data and source code are available at https://github.com/Mihir3009/LongBoX.

Self-disclosure, while being common and rewarding in social media interaction, also poses privacy risks. In this paper, we take the initiative to protect the user-side privacy associated with online self-disclosure through identification and abstraction. We develop a taxonomy of 19 self-disclosure categories, and curate a large corpus consisting of 4.8K annotated disclosure spans. We then fine-tune a language model for identification, achieving over 75% in Token F$_1$. We further conduct a HCI user study, with 82\% of participants viewing the model positively, highlighting its real world applicability. Motivated by the user feedback, we introduce the task of self-disclosure abstraction. We experiment with both one-span abstraction and three-span abstraction settings, and explore multiple fine-tuning strategies. Our best model can generate diverse abstractions that moderately reduce privacy risks while maintaining high utility according to human evaluation.

Neural knowledge-to-text generation models often struggle to faithfully generate descriptions for the input facts: they may produce hallucinations that contradict the given facts, or describe facts not present in the input. To reduce hallucinations, we propose a novel decoding method, TWEAK (Think While Effectively Articulating Knowledge). TWEAK treats the generated sequences at each decoding step and its future sequences as hypotheses, and ranks each generation candidate based on how well their corresponding hypotheses support the input facts using a Hypothesis Verification Model (HVM). We first demonstrate the effectiveness of TWEAK by using a Natural Language Inference (NLI) model as the HVM and report improved faithfulness with minimal impact on the quality. We then replace the NLI model with our task-specific HVM trained with a first-of-a-kind dataset, FATE (Fact-Aligned Textual Entailment), which pairs input facts with their faithful and hallucinated descriptions with the hallucinated spans marked. The new HVM improves the faithfulness and the quality further and runs faster. Overall the best TWEAK variants improve on average 2.22/7.17 points on faithfulness measured by FactKB over WebNLG and TekGen/GenWiki, respectively, with only 0.14/0.32 points degradation on quality measured by BERTScore over the same datasets. Since TWEAK is a decoding-only approach, it can be integrated with any neural generative model without retraining.

Intrusion Tolerant Systems (ITSs) are a necessary component for cyber-services/infrastructures. Additionally, as cyberattacks follow a multi-domain attack surface, a similar defensive approach should be applied, namely, the use of an evolving multi-disciplinary solution that combines ITS, cybersecurity and Artificial Intelligence (AI). With the increased popularity of AI solutions, due to Big Data use-case scenarios and decision support and automation scenarios, new opportunities to apply Machine Learning (ML) algorithms have emerged, namely ITS empowerment. Using ML algorithms, an ITS can augment its intrusion tolerance capability, by learning from previous attacks and from known vulnerabilities. As such, this work's contribution is twofold: (1) an ITS architecture (Skynet) based on the state-of-the-art and incorporates new components to increase its intrusion tolerance capability and its adaptability to new adversaries; (2) an improved Risk Manager design that leverages AI to improve ITSs by automatically assessing OS risks to intrusions, and advise with safer configurations. One of the reasons that intrusions are successful is due to bad configurations or slow adaptability to new threats. This can be caused by the dependency that systems have for human intervention. One of the characteristics in Skynet and HAL 9000 design is the removal of human intervention. Being fully automatized lowers the chance of successful intrusions caused by human error. Our experiments using Skynet, shows that HAL is able to choose 15% safer configurations than the state-of-the-art risk manager.

Parameter-efficient fine-tuning (PEFT) using labeled task data can significantly improve the performance of large language models (LLMs) on the downstream task. However, there are 7000 languages in the world and many of these languages lack labeled data for real-world language generation tasks. In this paper, we propose to improve zero-shot cross-lingual transfer by composing language or task specialized parameters. Our method composes language and task PEFT modules via element-wise arithmetic operations to leverage unlabeled data and English labeled data. We extend our approach to cases where labeled data from more languages is available and propose to arithmetically compose PEFT modules trained on languages related to the target. Empirical results on summarization demonstrate that our method is an effective strategy that obtains consistent gains using minimal training of PEFT modules.

In the era of Large Language Models (LLMs), human-computer interaction has evolved towards natural language, offering unprecedented flexibility. Despite this, LLMs are heavily reliant on well-structured prompts to function efficiently within the realm of In-Context Learning. Vanilla In-Context Learning relies on human-provided contexts, such as labeled examples, explicit instructions, or other guiding mechanisms that shape the model's outputs. To address this challenge, our study presents a universal framework named Automatic In-Context Learning. Upon receiving a user's request, we ask the model to independently generate examples, including labels, instructions, or reasoning pathways. The model then leverages this self-produced context to tackle the given problem. Our approach is universally adaptable and can be implemented in any setting where vanilla In-Context Learning is applicable. We demonstrate that our method yields strong performance across a range of tasks, standing up well when compared to existing methods.

Accurately predicting drug-drug interactions (DDI) for emerging drugs, which offer possibilities for treating and alleviating diseases, with computational methods can improve patient care and contribute to efficient drug development. However, many existing computational methods require large amounts of known DDI information, which is scarce for emerging drugs. In this paper, we propose EmerGNN, a graph neural network (GNN) that can effectively predict interactions for emerging drugs by leveraging the rich information in biomedical networks. EmerGNN learns pairwise representations of drugs by extracting the paths between drug pairs, propagating information from one drug to the other, and incorporating the relevant biomedical concepts on the paths. The different edges on the biomedical network are weighted to indicate the relevance for the target DDI prediction. Overall, EmerGNN has higher accuracy than existing approaches in predicting interactions for emerging drugs and can identify the most relevant information on the biomedical network.

Multilingual language models are widely used to extend NLP systems to lowresource languages. However, concrete evidence for the effects of multilinguality on language modeling performance in individual languages remains scarce. Here, we pre-train over 10,000 monolingual and multilingual language models for over 250 languages, including multiple language families that are understudied in NLP. We assess how language modeling performance in each language varies as a function of (1) monolingual dataset size, (2) added multilingual dataset size, (3) linguistic similarity of the added languages, and (4) model size (up to 45M parameters). We find that in moderation, adding multilingual data improves low-resource language modeling performance, similar to increasing low-resource dataset sizes by up to 33%. Improvements depend on the syntactic similarity of the added multilingual data, with marginal additional effects of vocabulary overlap. However, high-resource languages consistently perform worse in multilingual pre-training scenarios. As dataset sizes increase, adding multilingual data begins to hurt performance for both low-resource and high-resource languages, likely due to limited model capacity (the "curse of multilinguality"). These results suggest that massively multilingual pre-training may not be optimal for any languages involved, but that more targeted models can significantly improve performance. Multilingual language models have been a fixture of natural language processing (NLP) research nearly since the introduction of Transformer language models (Devlin et al., 2019; Conneau et al., 2020a). However, while multilingual language models produce strong results across many languages, multilingual pre-training work almost exclusively focuses on pre-training a small number of models with some fixed distribution over languages (e.g. Thus, it is largely unknown how different pre-training language distributions, such as different quantities of multilingual data or different selections of languages, affect multilingual language model performance. Fujinuma et al. (2022) vary the set of pre-training languages, but they consider only 14 variations of 14 languages, and they focus on cross-lingual transfer after English fine-tuning. Figure 1: Left: Map of the 252 languages used in our study.

Powerful large language models have facilitated the development of writing assistants that promise to significantly improve the quality and efficiency of composition and communication. However, a barrier to effective assistance is the lack of personalization in LLM outputs to the author's communication style and specialized knowledge. In this paper, we address this challenge by proposing PEARL, a retrieval-augmented LLM writing assistant personalized with a generation-calibrated retriever. Our retriever is trained to select historic user-authored documents for prompt augmentation, such that they are likely to best personalize LLM generations for a user request. We propose two key novelties for training our retriever: 1) A training data selection method that identifies user requests likely to benefit from personalization and documents that provide that benefit; and 2) A scale-calibrating KL-divergence objective that ensures that our retriever closely tracks the benefit of a document for personalized generation. We demonstrate the effectiveness of PEARL in generating personalized workplace social media posts and Reddit comments. Finally, we showcase the potential of a generation-calibrated retriever to double as a performance predictor and further improve low-quality generations via LLM chaining.

In this paper, we tackle the significant challenge of temporal knowledge reasoning in Large Language Models (LLMs), an area where such models frequently encounter difficulties. These difficulties often result in the generation of misleading or incorrect information, primarily due to their limited capacity to process evolving factual knowledge and complex temporal logic. In response, we propose a novel, constructivism-based approach that advocates for a paradigm shift in LLM learning towards an active, ongoing process of knowledge synthesis and customization. At the heart of our proposal is the Abstract Reasoning Induction ARI framework, which divides temporal reasoning into two distinct phases: Knowledge-agnostic and Knowledge-based. This division aims to reduce instances of hallucinations and improve LLMs' capacity for integrating abstract methodologies derived from historical data. Our approach achieves remarkable improvements, with relative gains of 29.7\% and 9.27\% on two temporal QA datasets, underscoring its efficacy in advancing temporal reasoning in LLMs. The code will be released at https://github.com/czy1999/ARI.