Foundation models (FMs) learn from large volumes of unlabeled data to demonstrate superior performance across a wide range of tasks. However, FMs developed for biomedical domains have largely remained unimodal, i.e., independently trained and used for tasks on protein sequences alone, small molecule structures alone, or clinical data alone. To overcome this limitation, we present BioBRIDGE, a parameter-efficient learning framework, to bridge independently trained unimodal FMs to establish multimodal behavior. BioBRIDGE achieves it by utilizing Knowledge Graphs (KG) to learn transformations between one unimodal FM and another without fine-tuning any underlying unimodal FMs. Our results demonstrate that BioBRIDGE can beat the best baseline KG embedding methods (on average by 76.3%) in cross-modal retrieval tasks. We also identify BioBRIDGE demonstrates out-of-domain generalization ability by extrapolating to unseen modalities or relations. Additionally, we also show that BioBRIDGE presents itself as a general-purpose retriever that can aid biomedical multimodal question answering as well as enhance the guided generation of novel drugs. Foundation models (Bommasani et al., 2021) trained on large volumes of data can be leveraged and adapted for different domains. In biomedicine, FMs are trained to ingest text corpora (Gu et al., 2021) from scientific literature, protein data in sequences and 3D-structures (Jumper et al., 2021), molecule in graphs and SMILES strings (Fabian et al., 2020) and protein-interaction data in the form of relational graphs. These pre-trained biomedical FMs have achieved a significant gain in comparison to previous methods trained on smaller datasets (Qiu et al., 2023). Introducing multimodal data in training further boosts the performance of FMs, especially in few-shot/zero-shot prediction settings (Radford et al., 2021). In the biomedical domain, for drug-text (Edwards et al., 2022), protein-text (Liu et al., 2023), and drug-protein data (Huang et al., 2021; Ioannidis et al., 2020), multimodal data was leveraged by the joint optimization of unimodal encoders. However, this idea encounters key issues when scaling beyond two modalities: Computational Cost.

Compositional generalization is a key ability of humans that enables us to learn new concepts from only a handful examples. Neural machine learning models, including the now ubiquitous Transformers, struggle to generalize in this way, and typically require thousands of examples of a concept during training in order to generalize meaningfully. This difference in ability between humans and artificial neural architectures, motivates this study on a neuro-symbolic architecture called the Compositional Program Generator (CPG). CPG has three key features: \textit{modularity}, \textit{composition}, and \textit{abstraction}, in the form of grammar rules, that enable it to generalize both systematically to new concepts in a few-shot manner, as well as productively by length on various sequence-to-sequence language tasks. For each input, CPG uses a grammar of the input language and a parser to generate a parse in which each grammar rule is assigned its own unique semantic module, a probabilistic copy or substitution program. Instances with the same parse are always processed with the same composed modules, while those with different parses may be processed with different modules. CPG learns parameters for the modules and is able to learn the semantics for new rules and types incrementally, without forgetting or retraining on rules it's already seen. It achieves perfect generalization on both the SCAN and COGS benchmarks using just 14 examples for SCAN and 22 examples for COGS -- state-of-the-art accuracy with a 1000x improvement in sample efficiency.

Music streaming services heavily rely on their recommendation engines to continuously provide content to their consumers. Sequential recommendation consequently has seen considerable attention in current literature, where state of the art approaches focus on self-attentive models leveraging contextual information such as long and short-term user history and item features; however, most of these studies focus on long-form content domains (retail, movie, etc.) rather than short-form, such as music. Additionally, many do not explore incorporating negative session-level feedback during training. In this study, we investigate the use of transformer-based self-attentive architectures to learn implicit session-level information for sequential music recommendation. We additionally propose a contrastive learning task to incorporate negative feedback (e.g skipped tracks) to promote positive hits and penalize negative hits. This task is formulated as a simple loss term that can be incorporated into a variety of deep learning architectures for sequential recommendation. Our experiments show that this results in consistent performance gains over the baseline architectures ignoring negative user feedback.

Although diffusion models (DMs) have shown promising performances in a number of tasks (e.g., speech synthesis and image generation), they might suffer from error propagation because of their sequential structure. However, this is not certain because some sequential models, such as Conditional Random Field (CRF), are free from this problem. To address this issue, we develop a theoretical framework to mathematically formulate error propagation in the architecture of DMs, The framework contains three elements, including modular error, cumulative error, and propagation equation. The modular and cumulative errors are related by the equation, which interprets that DMs are indeed affected by error propagation. Our theoretical study also suggests that the cumulative error is closely related to the generation quality of DMs. Based on this finding, we apply the cumulative error as a regularization term to reduce error propagation. Because the term is computationally intractable, we derive its upper bound and design a bootstrap algorithm to efficiently estimate the bound for optimization. We have conducted extensive experiments on multiple image datasets, showing that our proposed regularization reduces error propagation, significantly improves vanilla DMs, and outperforms previous baselines.

We propose a learning-based framework for efficient power allocation in ad hoc interference networks under episodic constraints. The problem of optimal power allocation -- for maximizing a given network utility metric -- under instantaneous constraints has recently gained significant popularity. Several learnable algorithms have been proposed to obtain fast, effective, and near-optimal performance. However, a more realistic scenario arises when the utility metric has to be optimized for an entire episode under time-coupled constraints. In this case, the instantaneous power needs to be regulated so that the given utility can be optimized over an entire sequence of wireless network realizations while satisfying the constraint at all times. Solving each instance independently will be myopic as the long-term constraint cannot modulate such a solution. Instead, we frame this as a constrained and sequential decision-making problem, and employ an actor-critic algorithm to obtain the constraint-aware power allocation at each step. We present experimental analyses to illustrate the effectiveness of our method in terms of superior episodic network-utility performance and its efficiency in terms of time and computational complexity.

Categorical variables often appear in datasets for classification and regression tasks, and they need to be encoded into numerical values before training. Since many encoders have been developed and can significantly impact performance, choosing the appropriate encoder for a task becomes a time-consuming yet important practical issue. This study broadly classifies machine learning models into three categories: 1) ATI models that implicitly perform affine transformations on inputs, such as multi-layer perceptron neural network; 2) Tree-based models that are based on decision trees, such as random forest; and 3) the rest, such as kNN. Theoretically, we prove that the one-hot encoder is the best choice for ATI models in the sense that it can mimic any other encoders by learning suitable weights from the data. We also explain why the target encoder and its variants are the most suitable encoders for tree-based models. This study conducted comprehensive computational experiments to evaluate 14 encoders, including one-hot and target encoders, along with eight common machine-learning models on 28 datasets. The computational results agree with our theoretical analysis. The findings in this study shed light on how to select the suitable encoder for data scientists in fields such as fraud detection, disease diagnosis, etc.

This paper introduces ClimateGPT, a model family of domain-specific large language models that synthesize interdisciplinary research on climate change. We trained two 7B models from scratch on a science-oriented dataset of 300B tokens. For the first model, the 4.2B domain-specific tokens were included during pre-training and the second was adapted to the climate domain after pre-training. Additionally, ClimateGPT-7B, 13B and 70B are continuously pre-trained from Llama~2 on a domain-specific dataset of 4.2B tokens. Each model is instruction fine-tuned on a high-quality and human-generated domain-specific dataset that has been created in close cooperation with climate scientists. To reduce the number of hallucinations, we optimize the model for retrieval augmentation and propose a hierarchical retrieval strategy. To increase the accessibility of our model to non-English speakers, we propose to make use of cascaded machine translation and show that this approach can perform comparably to natively multilingual models while being easier to scale to a large number of languages. Further, to address the intrinsic interdisciplinary aspect of climate change we consider different research perspectives. Therefore, the model can produce in-depth answers focusing on different perspectives in addition to an overall answer. We propose a suite of automatic climate-specific benchmarks to evaluate LLMs. On these benchmarks, ClimateGPT-7B performs on par with the ten times larger Llama-2-70B Chat model while not degrading results on general domain benchmarks. Our human evaluation confirms the trends we saw in our benchmarks. All models were trained and evaluated using renewable energy and are released publicly.

In this work, we present Vlogger, a generic AI system for generating a minute-level video blog (i.e., vlog) of user descriptions. Different from short videos with a few seconds, vlog often contains a complex storyline with diversified scenes, which is challenging for most existing video generation approaches. To break through this bottleneck, our Vlogger smartly leverages Large Language Model (LLM) as Director and decomposes a long video generation task of vlog into four key stages, where we invoke various foundation models to play the critical roles of vlog professionals, including (1) Script, (2) Actor, (3) ShowMaker, and (4) Voicer. With such a design of mimicking human beings, our Vlogger can generate vlogs through explainable cooperation of top-down planning and bottom-up shooting. Moreover, we introduce a novel video diffusion model, ShowMaker, which serves as a videographer in our Vlogger for generating the video snippet of each shooting scene. By incorporating Script and Actor attentively as textual and visual prompts, it can effectively enhance spatial-temporal coherence in the snippet. Besides, we design a concise mixed training paradigm for ShowMaker, boosting its capacity for both T2V generation and prediction. Finally, the extensive experiments show that our method achieves state-of-the-art performance on zero-shot T2V generation and prediction tasks. More importantly, Vlogger can generate over 5-minute vlogs from open-world descriptions, without loss of video coherence on script and actor. The code and model is all available at https://github.com/zhuangshaobin/Vlogger.

Foley sound, audio content inserted synchronously with videos, plays a critical role in the user experience of multimedia content. Recently, there has been active research in Foley sound synthesis, leveraging the advancements in deep generative models. However, such works mainly focus on replicating a single sound class or a textual sound description, neglecting temporal information, which is crucial in the practical applications of Foley sound. We present T-Foley, a Temporal-event-guided waveform generation model for Foley sound synthesis. T-Foley generates high-quality audio using two conditions: the sound class and temporal event feature. For temporal conditioning, we devise a temporal event feature and a novel conditioning technique named Block-FiLM. T-Foley achieves superior performance in both objective and subjective evaluation metrics and generates Foley sound well-synchronized with the temporal events. Additionally, we showcase T-Foley's practical applications, particularly in scenarios involving vocal mimicry for temporal event control. We show the demo on our companion website.

Demystifying interactions between temporal patterns of different scales is fundamental to precise long-range time series forecasting. However, previous works lack the ability to model high-order interactions. To promote more comprehensive pattern interaction modeling for long-range time series forecasting, we propose a Multi-Scale Hypergraph Transformer (MSHyper) framework. Specifically, a multi-scale hypergraph is introduced to provide foundations for modeling high-order pattern interactions. Then by treating hyperedges as nodes, we also build a hyperedge graph to enhance hypergraph modeling. In addition, a tri-stage message passing mechanism is introduced to aggregate pattern information and learn the interaction strength between temporal patterns of different scales. Extensive experiments on five real-world datasets demonstrate that MSHyper achieves state-of-the-art performance, reducing prediction errors by an average of 8.73% and 7.15% over the best baseline in MSE and MAE, respectively.