The recent advance in Large Language Models (LLMs) has shaped a new paradigm of AI agents, i.e., LLM-based agents. Compared to standalone LLMs, LLM-based agents substantially extend the versatility and expertise of LLMs by enhancing LLMs with the capabilities of perceiving and utilizing external resources and tools. To date, LLM-based agents have been applied and shown remarkable effectiveness in Software Engineering (SE). The synergy between multiple agents and human interaction brings further promise in tackling complex real-world SE problems. In this work, we present a comprehensive and systematic survey on LLM-based agents for SE. We collect 106 papers and categorize them from two perspectives, i.e., the SE and agent perspectives. In addition, we discuss open challenges and future directions in this critical domain. The repository of this survey is at https://github.com/FudanSELab/Agent4SE-Paper-List.

The routing results are playing an increasingly important role in transportation efficiency, but they could generate traffic congestion unintentionally. This is because the traffic condition and routing system are disconnected components in the current routing paradigm. In this paper, we propose a next-generation routing paradigm that could reduce traffic congestion by considering the influence of the routing results in real-time. Specifically, we regard the routing results as the root cause of the future traffic flow, which at the same time is identified as the root cause of traffic conditions. To implement such a system, we identify three essential components: 1) the traffic condition simulation that establishes the relation between traffic flow and traffic condition with guaranteed accuracy; 2) the future route management that supports efficient simulation with dynamic route update; 3) the global routing optimization that improves the overall transportation system efficiency. Preliminary design and experimental results will be presented, and the corresponding challenges and research directions will also be discussed.

Computer-aided cancer survival risk prediction plays an important role in the timely treatment of patients. This is a challenging weakly supervised ordinal regression task associated with multiple clinical factors involved such as pathological images, genomic data and etc. In this paper, we propose a new training method, multimodal object-level contrast learning, for cancer survival risk prediction. First, we construct contrast learning pairs based on the survival risk relationship among the samples in the training sample set. Then we introduce the object-level contrast learning method to train the survival risk predictor. We further extend it to the multimodal scenario by applying cross-modal constrast. Considering the heterogeneity of pathological images and genomics data, we construct a multimodal survival risk predictor employing attention-based and self-normalizing based nerural network respectively. Finally, the survival risk predictor trained by our proposed method outperforms state-of-the-art methods on two public multimodal cancer datasets for survival risk prediction.

When designing a public transportation network in a country, one may want to minimise the sum of travel duration of all inhabitants. This corresponds to a purely utilitarian view and does not involve any fairness consideration, as the resulting network will typically benefit the capital city and/or large central cities while leaving some peripheral cities behind. On the other hand, a more egalitarian view will allow some people to travel between peripheral cities without having to go through a central city. We define a model, propose algorithms for computing solution networks, and report on experiments based on real data.

Adverse conditions like snow, rain, nighttime, and fog, pose challenges for autonomous driving perception systems. Existing methods have limited effectiveness in improving essential computer vision tasks, such as semantic segmentation, and often focus on only one specific condition, such as removing rain or translating nighttime images into daytime ones. To address these limitations, we propose a method to improve the visual quality and clarity degraded by such adverse conditions. Our method, AllWeather-Net, utilizes a novel hierarchical architecture to enhance images across all adverse conditions. This architecture incorporates information at three semantic levels: scene, object, and texture, by discriminating patches at each level. Furthermore, we introduce a Scaled Illumination-aware Attention Mechanism (SIAM) that guides the learning towards road elements critical for autonomous driving perception. SIAM exhibits robustness, remaining unaffected by changes in weather conditions or environmental scenes. AllWeather-Net effectively transforms images into normal weather and daytime scenes, demonstrating superior image enhancement results and subsequently enhancing the performance of semantic segmentation, with up to a 5.3% improvement in mIoU in the trained domain. We also show our model's generalization ability by applying it to unseen domains without re-training, achieving up to 3.9% mIoU improvement. Code can be accessed at: https://github.com/Jumponthemoon/AllWeatherNet.

In recent years, artificial intelligence (AI) has made significant progress in the field of music generation, driving innovation in music creation and applications. This paper provides a systematic review of the latest research advancements in AI music generation, covering key technologies, models, datasets, evaluation methods, and their practical applications across various fields. The main contributions of this review include: (1) presenting a comprehensive summary framework that systematically categorizes and compares different technological approaches, including symbolic generation, audio generation, and hybrid models, helping readers better understand the full spectrum of technologies in the field; (2) offering an extensive survey of current literature, covering emerging topics such as multimodal datasets and emotion expression evaluation, providing a broad reference for related research; (3) conducting a detailed analysis of the practical impact of AI music generation in various application domains, particularly in real-time interaction and interdisciplinary applications, offering new perspectives and insights; (4) summarizing the existing challenges and limitations of music quality evaluation methods and proposing potential future research directions, aiming to promote the standardization and broader adoption of evaluation techniques. Through these innovative summaries and analyses, this paper serves as a comprehensive reference tool for researchers and practitioners in AI music generation, while also outlining future directions for the field.

Computer system creativity is a key step on the pathway to artificial general intelligence (AGI). It is elusive, however, due to the fact that human creativity is not fully understood and, thus, it is difficult to develop this capability in software. Large language models (LLMs) provide a facsimile of creativity and the appearance of sentience, while not actually being either creative or sentient. While LLMs have created bona fide new content, in some cases - such as with harmful hallucinations - inadvertently, their deliberate creativity is seen by some to not match that of humans. In response to this challenge, this paper proposes a technique for enhancing LLM output creativity via an iterative process of concept injection and refinement. Initial work on the development of the Creative Artificial Intelligence through Recurring Developments and Determinations (CAIRDD) system is presented and the efficacy of key system components is evaluated.

Biopharmaceutical products, particularly monoclonal antibodies (mAbs), have gained prominence in the pharmaceutical market due to their high specificity and efficacy. As these products are projected to constitute a substantial portion of global pharmaceutical sales, the application of machine learning models in mAb development and manufacturing is gaining momentum. This paper addresses the critical need for uncertainty quantification in machine learning predictions, particularly in scenarios with limited training data. Leveraging ensemble learning and Monte Carlo simulations, our proposed method generates additional input samples to enhance the robustness of the model in small training datasets. We evaluate the efficacy of our approach through two case studies: predicting antibody concentrations in advance and real-time monitoring of glucose concentrations during bioreactor runs using Raman spectra data. Our findings demonstrate the effectiveness of the proposed method in estimating the uncertainty levels associated with process performance predictions and facilitating real-time decision-making in biopharmaceutical manufacturing. This contribution not only introduces a novel approach for uncertainty quantification but also provides insights into overcoming challenges posed by small training datasets in bioprocess development. The evaluation demonstrates the effectiveness of our method in addressing key challenges related to uncertainty estimation within upstream cell cultivation, illustrating its potential impact on enhancing process control and product quality in the dynamic field of biopharmaceuticals.

The amount of training compute used by frontier large language models (LLMs) increased by 5000x between the release of GPT-2 in 2019 and GPT-4 in 2023 and estimates from Epoch AI suggest a similar increase over the next six years. How does this massive increase in model training compute map onto performance? The empirical machine learning literature has derived remarkably consistent'scaling laws' suggesting a strong relationship between a model's training compute and model perplexity, a measure of model loss, across more than seven orders of magnitude. But there is so far a very limited understanding of how this reduction in perplexity affects key economic and social outcomes. This paper aims to offer the first experimental evidence on this question by conducting a randomized controlled trial(RCT) involving 300 professional translators conducting 1800 tasks of varying complexities. The participants were randomly assigned to either treatment groups where they could utilize one of thirteen LLMs of differing model training compute to help them complete their task or to a control group where they completed tasks without any AI assistance. Participants face high-powered incentives with significant bonus payments for high-quality tasks as evaluated by three experienced professionals in the field. The key outcome variables, therefore, were how translator's time taken, quality of tasks completed, and earnings per minute (inclusive of bonuses) varied by model training compute.

Building high-quality datasets for specialized tasks is a time-consuming and resource-intensive process that often requires specialized domain knowledge. We propose Corpus Retrieval and Augmentation for Fine-Tuning (CRAFT), a method for generating synthetic datasets, given a small number of user-written few-shots that demonstrate the task to be performed. Given the few-shot examples, we use large-scale public web-crawled corpora and similarity-based document retrieval to find other relevant human-written documents. Lastly, instruction-tuned large language models (LLMs) augment the retrieved documents into custom-formatted task samples, which then can be used for fine-tuning. We demonstrate that CRAFT can efficiently generate large-scale task-specific training datasets for four diverse tasks: biology question-answering (QA), medicine QA and commonsense QA as well as summarization. Our experiments show that CRAFT-based models outperform or achieve comparable performance to general LLMs for QA tasks, while CRAFT-based summarization models outperform models trained on human-curated data by 46 preference points.