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Bayesian inference for hierarchical models can be very challenging. MCMC methods have difficulty scaling to large models with many observations and latent variables. While variational inference (VI) and reweighted wake-sleep (RWS) can be more scalable, they are gradient-based methods and so often require many iterations to converge. Our key insight was that modern massively parallel importance weighting methods (Bowyer et al., 2024) give fast and accurate posterior moment estimates, and we can use these moment estimates to rapidly learn an approximate posterior. Specifically, we propose using expectation maximization to fit the approximate posterior, which we call QEM. The expectation step involves computing the posterior moments using high-quality massively parallel estimates from Bowyer et al. (2024). The maximization step involves fitting the approximate posterior using these moments, which can be done straightforwardly for simple approximate posteriors such as Gaussian, Gamma, Beta, Dirichlet, Binomial, Multinomial, Categorical, etc. (or combinations thereof). We show that QEM is faster than state-of-the-art, massively parallel variants of RWS and VI, and is invariant to reparameterizations of the model that dramatically slow down gradient based methods.

The Knowledge Graph Completion~(KGC) task aims to infer the missing entity from an incomplete triple. Existing embedding-based methods rely solely on triples in the KG, which is vulnerable to specious relation patterns and long-tail entities. On the other hand, text-based methods struggle with the semantic gap between KG triples and natural language. Apart from triples, entity contexts (e.g., labels, descriptions, aliases) also play a significant role in augmenting KGs. To address these limitations, we propose KGR3, a context-enriched framework for KGC. KGR3 is composed of three modules. Firstly, the Retrieval module gathers supporting triples from the KG, collects plausible candidate answers from a base embedding model, and retrieves context for each related entity. Then, the Reasoning module employs a large language model to generate potential answers for each query triple. Finally, the Re-ranking module combines candidate answers from the two modules mentioned above, and fine-tunes an LLM to provide the best answer. Extensive experiments on widely used datasets demonstrate that KGR3 consistently improves various KGC methods. Specifically, the best variant of KGR3 achieves absolute Hits@1 improvements of 12.3% and 5.6% on the FB15k237 and WN18RR datasets.

Enabling robots to autonomously navigate unknown, complex, dynamic environments and perform diverse tasks remains a fundamental challenge in developing robust autonomous physical agents. These agents must effectively perceive their surroundings while leveraging world knowledge for decision-making. Although recent approaches utilize vision-language and large language models for scene understanding and planning, they often rely on offline processing, offboard compute, make simplifying assumptions about the environment and perception, limiting real-world applicability. We present a novel framework for real-time onboard autonomous navigation in unknown environments that change over time by integrating multi-level abstraction in both perception and planning pipelines. Our system fuses data from multiple onboard sensors for localization and mapping and integrates it with open-vocabulary semantics to generate hierarchical scene graphs from continuously updated semantic object map. The LLM-based planner uses these graphs to create multi-step plans that guide low-level controllers in executing navigation tasks specified in natural language. The system's real-time operation enables the LLM to adjust its plans based on updates to the scene graph and task execution status, ensuring continuous adaptation to new situations or when the current plan cannot accomplish the task, a key advantage over static or rule-based systems. We demonstrate our system's efficacy on a quadruped navigating dynamic environments, showcasing its adaptability and robustness in diverse scenarios.

Knowledge Graphs (KGs) are foundational structures in many AI applications, representing entities and their interrelations through triples. However, triple-based KGs lack the contextual information of relational knowledge, like temporal dynamics and provenance details, which are crucial for comprehensive knowledge representation and effective reasoning. Instead, \textbf{Context Graphs} (CGs) expand upon the conventional structure by incorporating additional information such as time validity, geographic location, and source provenance. This integration provides a more nuanced and accurate understanding of knowledge, enabling KGs to offer richer insights and support more sophisticated reasoning processes. In this work, we first discuss the inherent limitations of triple-based KGs and introduce the concept of CGs, highlighting their advantages in knowledge representation and reasoning. We then present a context graph reasoning \textbf{CGR$^3$} paradigm that leverages large language models (LLMs) to retrieve candidate entities and related contexts, rank them based on the retrieved information, and reason whether sufficient information has been obtained to answer a query. Our experimental results demonstrate that CGR$^3$ significantly improves performance on KG completion (KGC) and KG question answering (KGQA) tasks, validating the effectiveness of incorporating contextual information on KG representation and reasoning.

Positive-Unlabelled (PU) learning is a growing field of machine learning that aims to learn classifiers from data consisting of labelled positive and unlabelled instances, which can be in reality positive or negative, but whose label is unknown. An extensive number of methods have been proposed to address PU learning over the last two decades, so many so that selecting an optimal method for a given PU learning task presents a challenge. Our previous work has addressed this by proposing GA-Auto-PU, the first Automated Machine Learning (Auto-ML) system for PU learning. In this work, we propose two new Auto-ML systems for PU learning: BO-Auto-PU, based on a Bayesian Optimisation approach, and EBO-Auto-PU, based on a novel evolutionary/Bayesian optimisation approach. We also present an extensive evaluation of the three Auto-ML systems, comparing them to each other and to well-established PU learning methods across 60 datasets (20 real-world datasets, each with 3 versions in terms of PU learning characteristics).

The increasing use of transformer-based large language models brings forward the challenge of processing long sequences. In document visual question answering (DocVQA), leading methods focus on the single-page setting, while documents can span hundreds of pages. We present GRAM, a method that seamlessly extends pre-trained single-page models to the multi-page setting, without requiring computationally-heavy pretraining. To do so, we leverage a single-page encoder for local page-level understanding, and enhance it with document-level designated layers and learnable tokens, facilitating the flow of information across pages for global reasoning. To enforce our model to utilize the newly introduced document-level tokens, we propose a tailored bias adaptation method. For additional computational savings during decoding, we introduce an optional compression stage using our C-Former model, which reduces the encoded sequence length, thereby allowing a tradeoff between quality and latency. Extensive experiments showcase GRAM's state-of-the-art performance on the benchmarks for multi-page DocVQA, demonstrating the effectiveness of our approach.

Pfizer Inc. is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. Pfizer develops and produces medicines and vaccines for immunology, oncology, cardiology, endocrinology, and neurology. The company has several blockbuster drugs or products that each generate more than US$1 billion in annual revenues.

A Long Island artificial intelligence startup has built software aimed at pinpointing U.S. counties where the COVID-19 outbreak is likely to be most deadly. In a June report, the data-mining company, Akai Kaeru LLC, forecast spiking COVID-19 mortality with the heaviest concentrations in counties of the Southeast, including Mississippi, Georgia and Louisiana, said co-founder and chief executive Klaus Mueller. Nationwide, the software found 985 out of all 3,007 U.S. counties are at risk. "These patterns identify groups of counties that have a steeper increase in the death-rate trajectory," he said. Closer to home, the software found Nassau and Suffolk counties are likely to be relatively stable, but Westchester and Rockland counties are potential tinderboxes that could tip into crisis, said Mueller, a computer science professor on leave from Stony Brook University.

Measles, once thought to have been eliminated in the U.S., is popping up in isolated outbreaks as a result of skipped well-child visits and parents' fears that the measles-mumps-rubella (MMR) vaccine is linked to autism. Though some 350 measles cases occurred in 15 states in the first three months of 2019, more than half were in Brooklyn, N.Y., and nearby Rockland County, N.Y., where large religious communities have adopted anti-vaccine positions. Rockland County responded by pulling 6,000 unvaccinated children out of schools and barring them from public places. The county's actions were effective; in just a few months, 17,500 doses of MMR were administered to area children. Yet, wouldn't it have been better to contain the outbreak before it got started?