Acetylcholine (ACh) has been implicated in a wide variety of tasks involving attentional processes and plasticity. Following extensive animal studies, it has previously been suggested that ACh reports on uncertainty and controls hippocampal, cortical and cortico-amygdalar plasticity. We extend this view and consider its effects on cortical representational inference, arguing that ACh controls the balance between bottom-up inference, influenced by input stimuli, and top-down inference, influenced by contextual information. We illustrate our proposal using a hierarchical hidden Markov model.

We introduce a new type of Self-Organizing Map (SOM) to navigate in the Semantic Space of large text collections. We propose a "hyperbolic SOM" (HSOM) based on a regular tesselation of the hyperbolic plane, which is a non-euclidean space characterized by constant negative gaussian curvature. The exponentially increasing size of a neighborhood around a point in hyperbolic space provides more freedom to map the complex information space arising from language into spatial relations. We describe experiments, showing that the HSOM can successfully be applied to text categorization tasks and yields results comparable to other state-of-the-art methods.

This paper presents reinforcement learning with a Long Short Term Memory recurrent neural network: RL-LSTM. Model-free RL-LSTM using Advantage(,x) learning and directed exploration can solve non-Markovian tasks with long-term dependencies between relevant events. This is demonstrated in a T-maze task, as well as in a difficult variation of the pole balancing task. 1 Introduction Reinforcement learning (RL) is a way of learning how to behave based on delayed reward signals [12]. Among the more important challenges for RL are tasks where part of the state of the environment is hidden from the agent. Such tasks are called non-Markovian tasks or Partially Observable Markov Decision Processes. Many real world tasks have this problem of hidden state. For instance, in a navigation task different positions in the environment may look the same, but one and the same action may lead to different next states or rewards. Thus, hidden state makes RL more realistic.

Motivated by our recent work on rooted tree matching, in this paper we provide a solution to the problem of matching two free (i.e., unrooted) trees by constructing an association graph whose maximal cliques are in one-to-one correspondence with maximal common subtrees. We then solve the problem using simple replicator dynamics from evolutionary game theory. Experiments on hundreds of uniformly random trees are presented. The results are impressive: despite the inherent inability of these simple dynamics to escape from local optima, they always returned a globally optimal solution.

We present a new approach to the supervised learning of lateral interactions for the competitive layer model (CLM) dynamic feature binding architecture. The method is based on consistency conditions, which were recently shown to characterize the attractor states of this linear threshold recurrent network. For a given set of training examples the learning problem is formulated as a convex quadratic optimization problem in the lateral interaction weights. An efficient dimension reduction of the learning problem can be achieved by using a linear superposition of basis interactions. We show the successful application of the method to a medical image segmentation problem of fluorescence microscope cell images.

We combine the replica approach from statistical physics with a variational approach to analyze learning curves analytically. We apply the method to Gaussian process regression. As a main result we derive approximative relations between empirical error measures, the generalization error and the posterior variance.

We propose a novel method for the analysis of sequential data that exhibits an inherent mode switching. In particular, the data might be a non-stationary time series from a dynamical system that switches between multiple operating modes. Unlike other approaches, our method processes the data incrementally and without any training of internal parameters. We use an HMM with a dynamically changing number of states and an online variant of the Viterbi algorithm that performs an unsupervised segmentation and classification of the data on-the-fly, i.e. the method is able to process incoming data in real-time. The main idea of the approach is to track and segment changes of the probability density of the data in a sliding window on the incoming data stream.

We provide a natural gradient method that represents the steepest descent direction based on the underlying structure of the parameter space. Although gradient methods cannot make large changes in the values of the parameters, we show that the natural gradient is moving toward choosing a greedy optimal action rather than just a better action. These greedy optimal actions are those that would be chosen under one improvement step of policy iteration with approximate, compatible value functions, as defined by Sutton et al. [9]. We then show drastic performance improvements in simple MDPs and in the more challenging MDP of Tetris. 1 Introduction There has been a growing interest in direct policy-gradient methods for approximate planning in large Markov decision problems (MDPs). Unfortunately, the standard gradient descent rule is noncovariant.

The adaptive TAP Gibbs free energy for a general densely connected probabilistic model with quadratic interactions and arbritary single site constraints is derived. We show how a specific sequential minimization of the free energy leads to a generalization of Minka's expectation propagation. Lastly, we derive a sparse representation version of the sequential algorithm. The usefulness of the approach is demonstrated on classification and density estimation with Gaussian processes and on an independent component analysis problem.

In this model, each training example is a set (or bag) of instances along with a single label equal to the maximum label among all instances in the bag. The individual instances within the bag are not given labels. The goal is to learn to accurately predict the label of previously unseen bags. Standard supervised learning can be viewed as a special case of MI learning where each bag holds a single instance. The MI learning model was originally motivated by the drug activity prediction problem where each instance is a possible conformation (or shape) of a molecule and each bag contains all likely low-energy conformations for the molecule.