We introduce the notion of Morton-style factorial coding and illustrate how it may help understand information integration and perceptual coding in the brain. We show that by focusing on average responses one may miss the existence of factorial coding mechanisms that become only apparent when analyzing spike count histograms. We show evidence suggesting that the classical/nonclassical receptive field organization in the cortex effectively enforces the development of Morton-style factorial codes. This may provide some cues to help understand perceptual coding in the brain and to develop new unsupervised learning algorithms. While methods like ICA (Bell & Sejnowski, 1997) develop independent codes, in Morton-style coding the goal is to make two or more external aspects of the world become independent when conditioning on internal representations.

In these types of synapses, the short-term dynamics of the synaptic efficacies are governed by the relative timing of the pre-and post-synaptic spikes, while on long time scales the efficacies tend asymptotically to either a potentiated state or to a depressed one. We fabricated a prototype VLSI chip containing a network of integrate and fire neurons interconnected via bistable STDP synapses. Test results from this chip demonstrate the synapse's STDP learning properties, and its long-term bistable characteristics.

We consider loopy belief propagation for approximate inference in probabilistic graphical models. A limitation of the standard algorithm is that clique marginals are computed as if there were no loops in the graph. To overcome this limitation, we introduce fractional belief propagation. Fractional belief propagation is formulated in terms of a family of approximate free energies, which includes the Bethe free energy and the naive mean-field free as special cases. Using the linear response correction of the clique marginals, the scale parameters can be tuned. Simulation results illustrate the potential merits of the approach.

Monaural speech separation has been studied in previous systems that incorporate auditory scene analysis principles. A major problem for these systems is their inability to deal with speech in the highfrequency range. Psychoacoustic evidence suggests that different perceptual mechanisms are involved in handling resolved and unresolved harmonics. Motivated by this, we propose a model for monaural separation that deals with low-frequency and highfrequency signals differently. For resolved harmonics, our model generates segments based on temporal continuity and cross-channel correlation, and groups them according to periodicity. For unresolved harmonics, the model generates segments based on amplitude modulation (AM) in addition to temporal continuity and groups them according to AM repetition rates derived from sinusoidal modeling. Underlying the separation process is a pitch contour obtained according to psychoacoustic constraints. Our model is systematically evaluated, and it yields substantially better performance than previous systems, especially in the high-frequency range.

In recent years variational methods have become a popular tool for approximate inference and learning in a wide variety of probabilistic models. For each new application, however, it is currently necessary first to derive the variational update equations, and then to implement them in application-specific code. Each of these steps is both time consuming and error prone. In this paper we describe a general purpose inference engine called VIBES ('Variational Inference for Bayesian Networks') which allows a wide variety of probabilistic models to be implemented and solved variationally without recourse to coding. New models are specified either through a simple script or via a graphical interface analogous to a drawing package. VIBES then automatically generates and solves the variational equations. We illustrate the power and flexibility of VIBES using examples from Bayesian mixture modelling.

Classification trees are one of the most popular types of classifiers, with ease of implementation and interpretation being among their attractive features. Despite the widespread use of classification trees, theoretical analysis of their performance is scarce. In this paper, we show that a new family of classification trees, called dyadic classification trees (DCTs), are near optimal (in a minimax sense) for a very broad range of classification problems. This demonstrates that other schemes (e.g., neural networks, support vector machines) cannot perform significantly better than DCTs in many cases. We also show that this near optimal performance is attained with linear (in the number of training data) complexity growing and pruning algorithms. Moreover, the performance of DCTs on benchmark datasets compares favorably to that of standard CART, which is generally more computationally intensive and which does not possess similar near optimality properties. Our analysis stems from theoretical results on structural risk minimization, on which the pruning rule for DCTs is based.

The extraction of a single high-quality image from a set of lowresolution images is an important problem which arises in fields such as remote sensing, surveillance, medical imaging and the extraction of still images from video. Typical approaches are based on the use of cross-correlation to register the images followed by the inversion of the transformation from the unknown high resolution image to the observed low resolution images, using regularization to resolve the ill-posed nature of the inversion process. In this paper we develop a Bayesian treatment of the super-resolution problem in which the likelihood function for the image registration parameters is based on a marginalization over the unknown high-resolution image. This approach allows us to estimate the unknown point spread function, and is rendered tractable through the introduction of a Gaussian process prior over images. Results indicate a significant improvement over techniques based on MAP (maximum a-posteriori) point optimization of the high resolution image and associated registration parameters. 1 Introduction The task in super-resolution is to combine a set of low resolution images of the same scene in order to obtain a single image of higher resolution. Provided the individual low resolution images have sub-pixel displacements relative to each other, it is possible to extract high frequency details of the scene well beyond the Nyquist limit of the individual source images.

We apply the replica method of Statistical Physics combined with a variational method to the approximate analytical computation of bootstrap averages for estimating the generalization error. We demonstrate our approach on regression with Gaussian processes and compare our results with averages obtained by Monte-Carlo sampling.

Recently, interest is growing to develop an effective communication interface connecting the human brain to a computer, the'Brain-Computer Interface' (BCI). One motivation of BCI research is to provide a new communication channel substituting normal motor output in patients with severe neuromuscular disabilities. In the last decade, various neurophysiological cortical processes, such as slow potential shifts, movement related potentials (MRPs) or event-related desynchronization (ERD) of spontaneous EEG rhythms, were shown to be suitable for BCI, and, consequently, different independent approaches of extracting BCI-relevant EEGfeatures for single-trial analysis are under investigation. Here, we present and systematically compare several concepts for combining such EEGfeatures to improve the single-trial classification. Feature combinations are evaluated on movement imagination experiments with 3 subjects where EEGfeatures are based on either MRPs or ERD, or both. Those combination methods that incorporate the assumption that the single EEGfeatures are physiologically mutually independent outperform the plain method of'adding' evidence where the single-feature vectors are simply concatenated. These results strengthen the hypothesis that MRP and ERD reflect at least partially independent aspects of cortical processes and open a new perspective to boost BCI effectiveness.

A standard view of memory consolidation is that episodes are stored temporarily in the hippocampus, and are transferred to the neocortex through replay. Various recent experimental challenges to the idea of transfer, particularly for human memory, are forcing its reevaluation. However, although there is independent neurophysiological evidence for replay, short of transfer, there are few theoretical ideas for what it might be doing. We suggest and demonstrate two important computational roles associated with neocortical indices.